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Editorial. Pitfalls in the practice of neurosurgery: identifying those at greatest risk
William T. Couldwell MD, PhD , Robert E. Harbaugh MD , and James T. Rutka MD, PhD
doi : 10.3171/2022.12.JNS222826
Volume 138: Issue 5 (May 2023)
Imaging-defined necrosis after treatment with single-fraction stereotactic radiosurgery and immune checkpoint inhibitors and its potential association with improved outcomes in patients with brain metastases: an international multicenter study of 697 patients
Eric J. Lehrer MD, MS , Manmeet S. Ahluwalia MD, MBA , Jason Gurewitz DO , Kenneth Bernstein MS , Douglas Kondziolka MD , Ajay Niranjan MD, MBA , Zhishuo Wei MSc , L. Dade Lunsford MD , Kareem R. Fakhoury MD , Chad G. Rusthoven MD , David Mathieu MD , Claire Trudel MD , Timothy D. Malouff MD , Henry Ruiz-Garcia MD , Phillip Bonney MD , Lindsay Hwang MD , Cheng Yu PhD , Gabriel Zada MD , Samir Patel MD , Christopher P. Deibert MD , Piero Picozzi MD , Andrea Franzini MD , Luca Attuati MD , Rahul N. Prasad MD , Raju R. Raval MD, DPhil , Joshua D. Palmer MD , Cheng-Chia Lee MD, PhD , Huai-Che Yang MD , Brianna M. Jones MD , Sheryl Green MBBCh , Jason P. Sheehan MD, PhD , and Daniel M. Trifiletti MD
doi : 10.3171/2022.7.JNS22752
Postoperative surveillance in cranial and spinal tumor neurosurgery: when is this warranted?
Stephanie Schipmann MD, PhD , Dorothee Cäcilia Spille MD , Marco Gallus MD , Sebastian Lohmann MPhil , Michael Schwake MD , Nils Warneke MD , Eric Suero Molina Dr med, MBA , Walter Stummer MD , and Markus Holling MD
doi : 10.3171/2022.7.JNS22691
The outbreak of COVID-19 and the sudden increase in the number of patients requiring mechanical ventilation significantly affected the management of neurooncological patients.
Surgery for glioblastomas in the elderly: an Association des Neuro-oncologues d’Expression Française (ANOCEF) trial
Florence Laigle-Donadey  MD , Philippe Metellus  MD, PhD , Jacques Guyotat  MD, PhD , Philippe Menei  MD, PhD , François Proust  MD, PhD , Henry Dufour  MD, PhD , Olivier Chinot  MD , Jérôme Honnorat  MD, PhD , Thierry Faillot  MD, MSc , Philippe Paquis  MD , Philippe Peruzzi  MD, PhD , Evelyne Emery  MD, PhD , Jean-Sébastien Guillamo  MD, PhD , Alexandre Carpentier  MD, PhD , Michel Wager  MD, PhD , Said Lebbah  MD , David Hajage  MD, PhD , Jean-Yves Delattre  MD , and Philippe Cornu  MD, PhD , on behalf of ANOCEF-IGCNO
doi : 10.3171/2022.8.JNS221068
The role of surgery in the treatment of malignant gliomas in the elderly is not settled. The authors conducted a randomized trial that compared tumor resection with biopsy only—both followed by standard therapy—in such patients.
Association of homotopic areas in the right hemisphere with language deficits in the short term after tumor resection
Shengyu Fang MD , Shimeng Weng MD , Lianwang Li MD , Yuhao Guo MD , Xing Fan MD , Zhong Zhang MD , Tao Jiang MD, , and Yinyan Wang MD
doi : 10.3171/2022.9.JNS221475
It is important to identify language deficit and recovery in the week following a tumor resection procedure. The homotopic Broca’s area and the superior longitudinal fasciculus in the right hemisphere participate in language functional compensation. However, the nodes in these structures, as well as their contributions to language rehabilitation, remain unknown. In this study, the authors investigated the association of homotopic areas in the right hemisphere with language deficit.
Recurrent insular low-grade gliomas: factors guiding the decision to reoperate
Lucas Ribeiro MD , Sam Ng MD , and Hugues Duffau MD, PhD
doi : 10.3171/2022.9.JNS221286
Reoperation has been established as an effective therapeutic strategy in recurrent diffuse low-grade gliomas (LGGs). Insular gliomas represent a specific surgical challenge because of the surrounding vascular and functional structures. The aim of this study was to investigate the main clinicoradiological factors guiding the decision to reoperate on recurrent insular LGGs (ILGGs).
Predictors of surgical site infection in glioblastoma patients undergoing craniotomy for tumor resection
Sumil K. Nair BA , David Botros MD , Sachiv Chakravarti , Yuncong Mao , Esther Wu , Brian Lu , Sophie Liu , Mazin Elshareif , Christopher M. Jackson MD , Gary L. Gallia MD, PhD , Chetan Bettegowda MD, PhD , Jon Weingart MD , Henry Brem MD , and Debraj Mukherjee MD, MPH
doi : 10.3171/2022.8.JNS212799
Surgical site infections (SSIs) burden patients and healthcare systems, often requiring additional intervention. The objective of this study was to identify the relationship between preoperative predictors inclusive of scalp incision type and postoperative SSI following glioblastoma resection.
Growth risk classification and typical growth speed of convexity, parasagittal, and falx meningiomas: a retrospective cohort study
Shuhei Yamada MD , Ryuichi Hirayama MD, PhD , Takamitsu Iwata MD , Hideki Kuroda MD , Tomoyoshi Nakagawa MD , Tomofumi Takenaka MD , Noriyuki Kijima MD, PhD , Yoshiko Okita MD, PhD , Naoki Kagawa MD, PhD , and Haruhiko Kishima MD, PhD
doi : 10.3171/2022.8.JNS221290
Meningiomas are the most common primary intracranial tumors, and their clinical and biological characteristics vary by location. Convexity, parasagittal, and falx meningiomas account for approximately 50%–65% of intracranial meningiomas.
Seizure outcome after resection of insular glioma: a systematic review, meta-analysis, and institutional experience
John J. Y. Zhang MBBS , Keng Siang Lee , Doris D. Wang MD, PhD , Shawn L. Hervey-Jumper MD , and Mitchel S. Berger MD
doi : 10.3171/2022.8.JNS221067
Gliomas arising from the insular cortex can be epileptogenic, with a significant proportion of patients having medically refractory epilepsy.
Association of preoperative glucose concentration with mortality in patients undergoing craniotomy for brain tumor
*Yu Zhang MD , Huiwen Tan MD , Lu Jia MD , Jialing He MD , Pengfei Hao MD , Tiangui Li MD , Yangchun Xiao MD , Liyuan Peng MD , Yuning Feng MD , Xin Cheng MD , Haidong Deng MD , Peng Wang MD , Weelic Chong MD , Yang Hai MD , Lvlin Chen MD , Chao You MD , and Fang Fang MD
doi : 10.3171/2022.9.JNS221251
Hyperglycemia is associated with worse outcomes in ambulatory settings and specialized hospital settings, but there are sparse data on the importance of preoperative blood glucose measurement before brain tumor craniotomy. The authors sought to investigate the association between preoperative glucose level and 30-day mortality rate in patients undergoing brain tumor resection.
Feasibility of bevacizumab-IRDye800CW as a tracer for fluorescence-guided meningioma surgery
*Bianca M. Dijkstra MD , Julie Nonnekens PhD , Wouter Nagengast MD, PhD , Schelto Kruijff MD, PhD , Gert Jan Meersma BASc , Wilfred F. A. den Dunnen MD, PhD , Frank A. E. Kruyt PhD , and Rob J. M. Groen MD, PhD
doi : 10.3171/2022.9.JNS221036
Meningiomas are frequently occurring, often benign intracranial tumors. Molecular fluorescence can be used to intraoperatively identify residual meningioma tissue and optimize safe resection; however, currently no clinically approved agent is available for this specific tumor type.
The longitudinal volumetric response of vestibular schwannomas after Gamma Knife radiosurgery
Luigi Albano MD , Hansen Deng MD , Zhishuo Wei BS , Lena Vodovotz BS , Ajay Niranjan MD, MBA , and L. Dade Lunsford MD
doi : 10.3171/2022.7.JNS22812
Gamma Knife radiosurgery (GKRS) is an effective treatment for vestibular schwannomas (VSs) and has been used in > 100,000 cases worldwide. In the present study the authors sought to define the serial volumetric tumor response of Koos grade I–IV VS after radiosurgery.
CD34 microvascularity in low-grade glioma: correlation with 5-aminolevulinic acid fluorescence and patient prognosis in a multicenter study at three specialized centers
Arthur Hosmann MD, PhD , Mohammed Jaber MD , Thomas Roetzer-Pejrimovsky MD , Gerald Timelthaler MSc , Martin Borkovec MSc , Barbara Kiesel MD , Lisa I. Wadiura MD, PhD , Matthias Millesi MD, PhD , Petra A. Mercea MD , Joanna Phillips MD , Shawn Hervey-Jumper MD , Anna S. Berghoff MD , Johannes A. Hainfellner MD , Mitchel S. Berger MD , Walter Stummer MD , and Georg Widhalm MD, PhD
doi : 10.3171/2022.7.JNS22921
Early markers are urgently needed in low-grade glioma (LGG) evaluation to rapidly estimate the individual patient’s prognosis and to determine the optimal postoperative management.
Use of heparin to rescue immunosuppressive monocyte reprogramming by glioblastoma-derived extracellular vesicles
Benjamin T. Himes MD, PhD , Cori E. Fain BS , Zachariah P. Tritz BA , Cody L. Nesvick MD , Helen J. Jin-Lee , Philipp A. Geiger MD , Timothy E. Peterson MS , Mi-Yeon Jung PhD , and Ian F. Parney MD, PhD
doi : 10.3171/2022.6.JNS2274
The profound immunosuppression found in glioblastoma (GBM) patients is a critical barrier to effective immunotherapy. Multiple mechanisms of tumor-mediated immune suppression exist, and the induction of immunosuppressive monocytes such as myeloid-derived suppressor cells (MDSCs) is increasingly appreciated as a key part of this pathology.
Gene expression analysis during progression of malignant meningioma compared to benign meningioma
Andrea D. Maier MD, PhD , Alessandra Meddis PhD , Christian Mirian MD , Jeppe Haslund-Vinding MD , Jiri Bartek Jr. MD, PhD , Sebastian M. Krog MD , Thi Uyen Phuong Nguyen BMLS , Aušrinė Areškevi�iūtė PhD , Linea C. Melchior PhD , Steffen Heegaard MD, PhD , Bjarne W. Kristensen MD, PhD , Tina N. Munch MD , Kåre Fugleholm MD, PhD , Morten Ziebell MD, PhD , David R. Raleigh MD, PhD , Frantz R. Poulsen MD, PhD , Thomas A. Gerds Dr rer nat , Thomas Litman PhD , David Scheie MD, PhD , and Tiit Mathiesen MD, PhD
doi : 10.3171/2022.7.JNS22585
Meningioma is the most common primary intracranial neoplasm. Only 1%–3% of meningiomas are malignant according to the 2016 WHO criteria (WHO grade III).
ZEB1 loss increases glioma stem cell tumorigenicity and resistance to chemoradiation
George K. Hanna MD , Mecca Madany PhD , Angelique Sao-Mai Sy Tay MD , Lincoln A. Edwards PhD , Sungjin Kim MS , Justin S. Michael MD , Miriam Nuno PhD , Tom Thomas PhD , Aiguo Li PhD , Dror Berel , Keith L. Black MD , Xuemo Fan MD, PhD , Wei Zhang PhD , Jeremy D. Rudnick MD , Rongfu Wang PhD , and John S. Yu MD
doi : 10.3171/2022.7.JNS22259
Glioblastoma has been known to be resistant to chemotherapy and radiation, whereas the underlying mechanisms of resistance have not been fully elucidated.
Prognostic value of an APOBEC3 deletion polymorphism for glioma patients in Taiwan
Chia-Hua Chen PhD , Kuo-Chen Wei MD , Wei-Chao Liao PhD , You-Yu Lin PhD , Hsiu-Chi Chen MSc , Li-Ying Feng BS , Chiung-Hui Liu PhD , Chiung-Yin Huang PhD , Ko-Ting Chen MD, PhD , Chi-Sheng Wu PhD , Yu-Sun Chang PhD , Jau-Song Yu PhD , and Ian Yi-Feng Chang PhD
doi : 10.3171/2022.7.JNS2250
The molecular pathogenesis of malignant gliomas, characterized by diverse tumor histology with differential prognosis, remains largely unelucidated.
Endonasal transsphenoidal surgery for planum sphenoidale versus tuberculum sellae meningiomas
Fraser Henderson Jr. MD , Brett E. Youngerman MD, MS , Sumit N. Niogi MD, PhD , Tyler Alexander BS , Abtin Tabaee MD , Ashutosh Kacker MD , Vijay K. Anand MD , and Theodore H. Schwartz MD
doi : 10.3171/2022.8.JNS22632
The aim of this study was to determine if the distinction between planum sphenoidale (PS) and tuberculum sellae (TS) meningiomas is clinically meaningful and impacts the results of the endoscopic endonasal approach (EEA).
A flow self-regulating superficial temporal artery–middle cerebral artery bypass based on side-to-side anastomosis for adult patients with moyamoya disease
Jianjian Zhang  MD, PhD , Jin Yu  MD, PhD , Can Xin  MD, PhD , Miki Fujimura  MD, PhD , Tsz Yeung Lau  MD, PhD , Miao Hu  MD , Xiao Tian  MM , Mingrui Luo  MM , Tianshu Tao  MM , Ling Li  MD, PhD , Changyin Wang  MD, PhD , Wei Wei  PhD , Xiang Li  PhD , and Jincao Chen  MD, PhD
doi : 10.3171/2022.8.JNS221379
Side-to-side (S-S) superficial temporal artery–middle cerebral artery (STA-MCA) bypass was reportedly used to treat a special moyamoya disease (MMD) patient with collaterals arising from the donor STA.
Predicting the growth of middle cerebral artery bifurcation aneurysms using differences in the bifurcation angle and inflow coefficient
Takeshi Miyata MD, PhD , Hiroharu Kataoka MD, PhD , Kampei Shimizu MD, PhD , Akihiro Okada MD , Takanobu Yagi PhD , Hirotoshi Imamura MD, PhD , Masaomi Koyanagi MD, PhD , Ryota Ishibashi MD , Masanori Goto MD, PhD , Nobuyuki Sakai MD, PhD , Taketo Hatano MD, PhD , Masaki Chin MD , Koichi Iwasaki MD, PhD , and Susumu Miyamoto MD, PhD
doi : 10.3171/2022.8.JNS22597
Growing intracranial aneurysms (IAs) are prone to rupture. Previous cross-sectional studies using postrupture morphology have shown the morphological or hemodynamic features related to IA rupture.
Use of heparin to rescue immunosuppressive monocyte reprogramming by glioblastoma-derived extracellular vesicles
Benjamin T. Himes MD, PhD , Cori E. Fain BS , Zachariah P. Tritz BA , Cody L. Nesvick MD , Helen J. Jin-Lee , Philipp A. Geiger MD , Timothy E. Peterson MS , Mi-Yeon Jung PhD , and Ian F. Parney MD, PhD
doi : 10.3171/2022.6.JNS2274
The profound immunosuppression found in glioblastoma (GBM) patients is a critical barrier to effective immunotherapy. Multiple mechanisms of tumor-mediated immune suppression exist, and the induction of immunosuppressive monocytes such as myeloid-derived suppressor cells (MDSCs) is increasingly appreciated as a key part of this pathology.
Gene expression analysis during progression of malignant meningioma compared to benign meningioma
Andrea D. Maier MD, PhD , Alessandra Meddis PhD , Christian Mirian MD , Jeppe Haslund-Vinding MD , Jiri Bartek Jr. MD, PhD , Sebastian M. Krog MD , Thi Uyen Phuong Nguyen BMLS , Aušrinė Areškevi�iūtė PhD , Linea C. Melchior PhD , Steffen Heegaard MD, PhD , Bjarne W. Kristensen MD, PhD , Tina N. Munch MD , Kåre Fugleholm MD, PhD , Morten Ziebell MD, PhD , David R. Raleigh MD, PhD , Frantz R. Poulsen MD, PhD , Thomas A. Gerds Dr rer nat , Thomas Litman PhD , David Scheie MD, PhD , and Tiit Mathiesen MD, PhD
doi : 10.3171/2022.7.JNS22585
Meningioma is the most common primary intracranial neoplasm. Only 1%–3% of meningiomas are malignant according to the 2016 WHO criteria (WHO grade III).
ZEB1 loss increases glioma stem cell tumorigenicity and resistance to chemoradiation
George K. Hanna MD , Mecca Madany PhD , Angelique Sao-Mai Sy Tay MD , Lincoln A. Edwards PhD , Sungjin Kim MS , Justin S. Michael MD , Miriam Nuno PhD , Tom Thomas PhD , Aiguo Li PhD , Dror Berel , Keith L. Black MD , Xuemo Fan MD, PhD , Wei Zhang PhD , Jeremy D. Rudnick MD , Rongfu Wang PhD , and John S. Yu MD
doi : 10.3171/2022.7.JNS22259
Glioblastoma has been known to be resistant to chemotherapy and radiation, whereas the underlying mechanisms of resistance have not been fully elucidated.
Prognostic value of an APOBEC3 deletion polymorphism for glioma patients in Taiwan
Chia-Hua Chen PhD , Kuo-Chen Wei MD , Wei-Chao Liao PhD , You-Yu Lin PhD , Hsiu-Chi Chen MSc , Li-Ying Feng BS , Chiung-Hui Liu PhD , Chiung-Yin Huang PhD , Ko-Ting Chen MD, PhD , Chi-Sheng Wu PhD , Yu-Sun Chang PhD , Jau-Song Yu PhD , and Ian Yi-Feng Chang PhD
doi : 10.3171/2022.7.JNS2250
The molecular pathogenesis of malignant gliomas, characterized by diverse tumor histology with differential prognosis, remains largely unelucidated.
Endonasal transsphenoidal surgery for planum sphenoidale versus tuberculum sellae meningiomas
Fraser Henderson Jr. MD , Brett E. Youngerman MD, MS , Sumit N. Niogi MD, PhD , Tyler Alexander BS , Abtin Tabaee MD , Ashutosh Kacker MD , Vijay K. Anand MD , and Theodore H. Schwartz MD
doi : 10.3171/2022.8.JNS22632
The aim of this study was to determine if the distinction between planum sphenoidale (PS) and tuberculum sellae (TS) meningiomas is clinically meaningful and impacts the results of the endoscopic endonasal approach (EEA).
A flow self-regulating superficial temporal artery–middle cerebral artery bypass based on side-to-side anastomosis for adult patients with moyamoya disease
Jianjian Zhang  MD, PhD , Jin Yu  MD, PhD , Can Xin  MD, PhD , Miki Fujimura  MD, PhD , Tsz Yeung Lau  MD, PhD , Miao Hu  MD , Xiao Tian  MM , Mingrui Luo  MM , Tianshu Tao  MM , Ling Li  MD, PhD , Changyin Wang  MD, PhD , Wei Wei  PhD , Xiang Li  PhD , and Jincao Chen  MD, PhD
doi : 10.3171/2022.8.JNS221379
Side-to-side (S-S) superficial temporal artery–middle cerebral artery (STA-MCA) bypass was reportedly used to treat a special moyamoya disease (MMD) patient with collaterals arising from the donor STA.
Predicting the growth of middle cerebral artery bifurcation aneurysms using differences in the bifurcation angle and inflow coefficient
Takeshi Miyata MD, PhD , Hiroharu Kataoka MD, PhD , Kampei Shimizu MD, PhD , Akihiro Okada MD , Takanobu Yagi PhD , Hirotoshi Imamura MD, PhD , Masaomi Koyanagi MD, PhD , Ryota Ishibashi MD , Masanori Goto MD, PhD , Nobuyuki Sakai MD, PhD , Taketo Hatano MD, PhD , Masaki Chin MD , Koichi Iwasaki MD, PhD , and Susumu Miyamoto MD, PhD
doi : 10.3171/2022.8.JNS22597
Growing intracranial aneurysms (IAs) are prone to rupture. Previous cross-sectional studies using postrupture morphology have shown the morphological or hemodynamic features related to IA rupture.
Cost-effectiveness analysis on small (< 5 mm) unruptured intracranial aneurysm follow-up strategies
Mira Salih MD , Mohamed Salem MD, MPH , Justin Moore MD, PhD , Ajith J. Thomas MD , and Christopher S. Ogilvy MD
doi : 10.3171/2022.8.JNS221053
Unruptured intracranial aneurysms are frequently detected during routine clinical diagnostic processes. A significant portion are small aneurysms less than 5 mm in diameter.
Short- and long-term outcomes of moyamoya patients post-revascularization
Mario Teo MD, FRCS(SN) , Kumar Abhinav MD, FRCS(SN) , Teresa E. Bell-Stephens BSN, RN, CNRN , Venkatesh S. Madhugiri MBBS, MCh , Eric S. Sussman MD , Tej Deepak Azad MD , Rohaid Ali MD , Rogelio Esparza MD , Michael Zhang MD , and Gary K. Steinberg MD, PhD
doi : 10.3171/2022.8.JNS22336
The post-bypass stroke risk factors and long-term outcomes of moyamoya patients are not well documented. Therefore, the authors studied 30-day stroke risks and patients’ long-term physical, functional, and social well-being.
Relationship between phenotypic features in Loeys-Dietz syndrome and the presence of intracranial aneurysms
*Anna L. Huguenard MD , Gabrielle W. Johnson BA , Rupen R. Desai MD , Joshua W. Osbun MD , Ralph G. Dacey MD , and Alan C. Braverman MD
doi : 10.3171/2022.9.JNS221373
Loeys-Dietz syndrome (LDS) is a rare autosomal dominant condition characterized by aneurysms of the aorta, aortic branches, and intracranial arteries; skeletal and cutaneous abnormalities; and craniofacial malformations.
Endovascular treatment of brain arteriovenous malformations: clinical outcomes of patients included in the registry of a pragmatic randomized trial
Jean Raymond MD , Jean-Christophe Gentric MD , Elsa Magro MD , Lorena Nico MD , Emma Bacchus BSc , Ruby Klink PhD , Christophe Cognard MD , Anne-Christine Januel MD , Jean-François Sabatier MD , Daniela Iancu MD , Alain Weill MD , Daniel Roy MD , Michel W. Bojanowski MD , Chiraz Chaalala MD , Xavier Barreau MD , Vincent Jecko MD , Chrysanthi Papagiannaki MD , Stéphane Derrey MD, PhD , Eimad Shotar MD , Philippe Cornu MD , Omer F. Eker MD, PhD , Isabelle Pelissou-Guyotat MD , Michel Piotin MD , Sorin Aldea MD , Rémy Beaujeux MD , François Proust MD , René Anxionnat MD , Vincent Costalat MD , Marine Le Corre MD , Jean-Yves Gauvrit MD , Xavier Morandi MD , Hervé Brunel MD , Pierre-Hugues Roche MD , Thomas Graillon MD , Emmanuel Chabert MD , Denis Herbreteau MD , Hubert Desal MD , Denis Trystram MD , Charlotte Barbier MD , Thomas Gaberel MD , Thanh N. Nguyen MD , Geraldine Viard RN , Guylaine Gevry BSc , Tim E. Darsaut MD , and the TOBAS Collaborative Group
doi : 10.3171/2022.9.JNS22987
The role of endovascular treatment in the management of patients with brain arteriovenous malformations (AVMs) remains uncertain.
Evaluating syntactic comprehension during awake intraoperative cortical stimulation mapping
Marco Riva MD , Stephen M. Wilson PhD , Ruofan Cai BA , Antonella Castellano MD, PhD , Kesshi M. Jordan PhD , Roland G. Henry PhD , Maria Luisa Gorno Tempini MD, PhD , Mitchel S. Berger MD , and Edward F. Chang MD
doi : 10.3171/2022.8.JNS221335
Electrocortical stimulation mapping (ECS) is widely used to identify essential language areas, but sentence-level processing has rarely been investigated.
Assessment of outcomes in consecutive patients undergoing dorsal scapular nerve decompression
Einar Ottestad MD and Thomas J. Wilson MD, MPH
doi : 10.3171/2022.7.JNS221223
Periscapular pain has a broad differential diagnosis. Dorsal scapular neuropathy is part of that differential diagnosis but is often forgotten by clinicians, leading to delayed diagnosis, chronic pain, and potentially worse outcomes.
Nerve transfers for brachial plexus injuries: grading of volitional control
Mariano Socolovsky MD, PhD , Karina Barillaro BSN , Gonzalo Bonilla MD , Gilda Di Masi MD , and Martijn Malessy MD, PhD
doi : 10.3171/2022.7.JNS22887
After brachial plexus injuries (BPIs), nerve transfers are used to restore lost muscle function. Brain plasticity underlies the process of regaining volitional control, which encompasses disconnection of the original donor nerve–related programs and reconnection to acceptor nerve programs.
Natural course of Rathke’s cleft cysts and risk factors for progression
Yasuyuki Kinoshita  MD, PhD , Akira Taguchi  MD , Fumiyuki Yamasaki  MD, PhD , Atsushi Tominaga  MD, PhD , Kazunori Arita  MD, PhD , and Nobutaka Horie  MD, PhD
doi : 10.3171/2022.7.JNS22716
Rathke’s cleft cysts (RCCs) are relatively common and often detected incidentally. They are usually asymptomatic and managed conservatively. However, little is known about their natural history. Thus, the authors aimed to examine the natural course of RCCs and identify the risk factors for their progression.
Evidence for a critical role of the left inferior parietal lobule and underlying white matter connectivity in proficient text reading
Sébastien Boissonneau MD, MSc , Anne-Laure Lemaître PhD , Guillaume Herbet PhD , Sam Ng MD, MSc , Hugues Duffau MD, PhD , and Sylvie Moritz-Gasser PhD
doi : 10.3171/2022.7.JNS22236
Microsurgical anatomy of the auditory radiations: revealing the enigmatic acoustic pathway from a surgical viewpoint
Aysegul Esen Aydin MD , Seckin Aydin MD , Berra Bilgin MD , Muyassar Mirkhasilova MD , Nicat Bayramli MD , and Necmettin Tanriover MD
doi : 10.3171/2022.7.JNS22247
The thalamocortical projections of the auditory system have not been detailed via microanatomical fiber dissections from a surgical viewpoint.
The Pierre Wertheimer Neurological and Neurosurgical Hospital in Lyon: history of its development and contributions to neurosurgery
Andrei Brînzeu MD, PhD and Marc Sindou MD, DSc, DHC
doi : 10.3171/2022.7.JNS212946
A modern history of neurosurgery and neurology in India: lessons for the world
Anurag Modak BA , Bharath Raju MBBS, MCh , Fareed Jumah MD , Margaret Pain MD , Gaurav Gupta MD , and Anil Nanda MD, MPH
doi : 10.3171/2022.7.JNS22456
The compendia of medical knowledge of the great ancient Indian physicians SuÅ›ruta, Caraka, JÄ«vaka, and VÄ�gbhaá¹a all attest to the practice of neurosurgery and neurology starting in the 1st millennium bce.
Obituary. Lynda Jun-San Yang, MD, PhD, 1967–2022
Cheerag D. Upadhyaya  MD, MBA, MSc , Miriana G. Popadich  NP-C, MSN , and John E. McGillicuddy  MD
Stimulating neurosurgery department research via goal-directed research training of residents
William J. Mack MD , Kavon P. Rezai-Zadeh PhD , and Stephen J. Korn PhD
Letter to the Editor. Challenges of immortal time biases in observational research
Letter to the Editor. ANOCEF trial: GBMs in elderly patients
Binghao Zhao MD , Hao Xing MD , and Wenbin Ma MD
