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Can We Prevent or Delay the Onset of Myopia?
David C. Musch, PhD, MPH1,2,3; Steven M. Archer, MD1
doi : 10.1001/jamaophthalmol.2023.0446
April 2023, Vol 141, No. 4, Pages 302-410
Estimation of Visual Function Using Deep Learning From Ultra-Widefield Fundus Images of Eyes With Retinitis Pigmentosa
Daisuke Nagasato, MD, PhD1,2,3; Takahiro Sogawa, MD1; Mao Tanabe, MD1; Hitoshi Tabuchi, MD, PhD, EMBA1,2,3; Shogo Numa, MD, PhD4; Akio Oishi, MD, PhD4,5; Hanako Ohashi Ikeda, MD, PhD4; Akitaka Tsujikawa, MD, PhD4; Tadao Maeda, MD, PhD6,7; Masayo Takahashi, MD, PhD6,7,8; Nana Ito, MD, PhD9; Gen Miura, MD, PhD9; Terumi Shinohara, MD2; Mariko Egawa, MD, PhD2; Yoshinori Mitamura, MD, PhD2
doi : 10.1001/jamaophthalmol.2022.6393
Importance There is no widespread effective treatment to halt the progression of retinitis pigmentosa. Consequently, adequate assessment and estimation of residual visual function are important clinically.
Diagnostic Accuracy of the Amsler Grid Test for Detecting Neovascular Age-Related Macular DegenerationA Systematic Review and Meta-analysis
Jakob Bjerager, MD1; Miklos Schneider, MD, PhD1,2; Ivan Potapenko, MD, PhD1; Elon H. C. van Dijk, MD, PhD3,4; Carsten Faber, MD, PhD1,5; Jakob Grauslund, MD, PhD, DMSc6,7,8; Kristina Pfau, MD9,10; Josef Huemer, MD11; Danson V. Muttuvelu, MD1,12; Marie L. R. Rasmussen, MD, PhD1,5; M. Cem Sabaner, MD13; Yousif Subhi, MD, PhD1,7
doi : 10.1001/jamaophthalmol.2022.6396
Importance Patients with nonneovascular age-related macular degeneration (AMD) are encouraged to use the Amsler grid test for self-assessment to facilitate early diagnosis. The test is widely recommended, suggesting a belief that it signals worsening AMD, warranting its use in home monitoring.
Incidence of Glaucoma-Related Adverse Events in the First 5 Years After Pediatric Lensectomy
Erick D. Bothun, MD1; Michael X. Repka, MD, MBA2; Raymond T. Kraker, MSPH3; Rui Wu, MS3; David A. Leske, MS1; Sarah R. Hatt, DBO1; Zhuokai Li, PhD3; Sharon F. Freedman, MD4; William F. Astle, MD5; Susan A. Cotter, OD, MS6; Jonathan M. Holmes, BM, BCh7; for the Pediatric Eye Disease Investigator Group
doi : 10.1001/jamaophthalmol.2022.6413
Importance Glaucoma can develop following cataract removal in children.
Evaluation and Follow-up of Myopia Prevalence Among School-Aged Children Subsequent to the COVID-19 Home Confinement in Feicheng, China
Jiaxing Wang, MD, PhD1; Yujie Han, BS2; David C. Musch, PhD, MPH3; Ying Li, MD, PhD1; Nan Wei, MD4; Xiaoli Qi, MD4; Gang Ding, MD4; Xue Li, MD4; Jing Li, MD4; Linlin Song, MD4; Ying Zhang, MD4; Yuxian Ning, MD4; Xiaoyu Zeng, MD4; Yaoling Li, MD4; Ling Sun, BS2; Ning Hua, MD4; Shuo Li, MD, PhD5; Sandra Jardines, BS1; Xuehan Qian, MD, PhD4
doi : 10.1001/jamaophthalmol.2022.6506
Importance Progression of myopia in a school-aged population due to home confinement (January to May 2021) during the COVID-19 pandemic has been previously reported. A key remaining question was whether the myopia spike in children aged 6 to 8 years persisted.
Factors Associated With Nasolacrimal Duct Probing Failure Among Children in the Intelligent Research in Sight Registry
Isdin Oke, MD1,2; Tobias Elze, PhD2; Joan W. Miller, MD2; Alice C. Lorch, MD, MPH2; David G. Hunter, MD, PhD1,2; Alexandra T. Elliott, MD1,2; for the IRIS Registry Analytic Center Consortium
doi : 10.1001/jamaophthalmol.2023.0004
Importance Understanding the factors associated with nasolacrimal duct probing failure in young children may help inform practice patterns.
Association of Rates of Ganglion Cell and Inner Plexiform Thinning With Development of Glaucoma in Eyes With Suspected Glaucoma
Vahid Mohammadzadeh, MD1; Sasan Moghimi, MD1; Takashi Nishida, MD1; Evan Walker, MS1; Alireza Kamalipour, MD, MPH1; Eleonora Micheletti, MD1; Golnoush Mahmoudinezhad, MD, MPH1; Jo-Hsuan Wu, MD1; Jeffrey M. Liebmann, MD2; Christopher A. Girkin, MD, MSPH3; Massimo Fazio, PhD1,3; Linda M. Zangwill, PhD1; Robert N. Weinreb, MD1
doi : 10.1001/jamaophthalmol.2023.0005
Importance In eyes with suspected glaucoma, it is clinically relevant to find diagnostic tests for the risk of development of perimetric glaucoma.
Comparison of Incremental Costs and Medicare Reimbursement for Simple vs Complex Cataract Surgery Using Time-Driven Activity-Based Costing
David S. Portney, MD1; Sean T. Berkowitz, MD, MBA2; Desmond C. Garner, BA2; Adel Qalieh, MD3; Vikram Tiwari, PhD4; Scott Friedman, MD5; Shriji Patel, MD, MBA2,8; Ravi Parikh, MD, MPH6,7; Shahzad I. Mian, MD1
doi : 10.1001/jamaophthalmol.2023.0091
Importance Cataract surgery is one of the most commonly performed surgeries across medicine and an integral part of ophthalmologic care. Complex cataract surgery requires more time and resources than simple cataract surgery, yet it remains unclear whether the incremental reimbursement for complex cataract surgery, compared with simple cataract surgery, offsets the increased costs.
Incidence and Progression of Diabetic Retinopathy in American Indian and Alaska Native Individuals Served by the Indian Health Service, 2015-2019
Stephanie J. Fonda, PhD1; Sven-Erik Bursell, PhD1; Drew G. Lewis, BA1; Dawn Clary, OD2; Dara Shahon, MD2; Jerry Cavallerano, OD, PhD3,4
doi : 10.1001/jamaophthalmol.2023.0167
Importance Estimates of diabetic retinopathy (DR) incidence and progression in American Indian and Alaska Native individuals are based on data from before 1992 and may not be informative for strategizing resources and practice patterns.
Financial Disclosures Reported by Industry Among Authors of the American Academy of Ophthalmology Clinical Practice Guidelines
Anne Xuan-Lan Nguyen1; Maxine Joly-Chevrier2; David-Dan Nguyen, MDCM, MPH3; Albert Y. Wu, MD, PhD4
doi : 10.1001/jamaophthalmol.2023.0267
Importance Recommendations of clinical guidelines affect physicians’ care delivery. Potential bias and undeclared conflicts of interests (COIs) among guideline authors can impact clinical practice decisions.
Perfluorohexyloctane Eye Drops for Dry Eye Disease Associated With Meibomian Gland Dysfunction in Chinese PatientsA Randomized Clinical Trial
Lei Tian, MD1; Zuojun Gao, MM2; Lei Zhu, MD3; Xiaoru Shi, MD4; Shaozhen Zhao, MD5; Hao Gu, MM6; Guoxing Xu, MM7; Linnong Wang, MM8; Hong Dai, MB9; Hong Zhang, MD10; Xiuming Jin, MD11; Ke Ma, MD12; Yonggen Xu, MD13; Lixiao Ma, MB14; Cheng Pei, MD15; Bilian Ke, MD16; Sonja Krösser, PhD17; Yunxia Zhang, MM2; Ying Jie, MD1
doi : 10.1001/jamaophthalmol.2023.0270
Importance Meibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye disease (DED). Medical and surgical management for DED is limited; therefore, new treatment options are sought.
Eyeing a Role for Artificial Intelligence in Clinical Trials
Mandeep S. Singh, MD, PhD1,2
Glaucoma Considerations in Pediatric Cataract Surgery
Eric Crouch, MD1,2
When 2 Epidemics Collide—COVID-19 and Myopia
David A. Mackey, MD1,2; Samantha S.Y. Lee, PhD1,2
Macular Optical Coherence Tomography—From Diagnosis to Prognostication
Joel S. Schuman, MD1,2,3,4,5
Time Is Long Past for Vision Scientists to Make Cataract Surgery More Efficient
Steven M. Kymes, PhD, MHA1
Use of Teleophthalmology to Evaluate the Incidence and Progression of Diabetic Retinopathy
Aleksandra Rachitskaya, MD1
Challenges of Assessing Disclosure Accuracy—All We Have Is Our Integrity
Will the Long-Named Perfluorohexyloctane Produce Long-lasting Improvements in Patients With Meibomian Gland Disease?
Gerami D. Seitzman, MD1,2; Thomas M. Lietman, MD1,2
Acute-Onset Orbital Inflammation in a Patient With Multiple Myeloma
George Villatoro, MD1; Nicole Topilow, MD1; Catherine Y. Liu, MD, PhD1
Monocular Vision Loss in a Patient With Earache and Night Sweats
Sarah Schimansky, MB BAO BCh, MEd1; Gary Cross, MBBS2; Ben Mulhearn, MBBS, PhD3,4
A Case of Acute Chest Pain After Acetazolamide to Treat Uncontrolled Increased Intraocular Pressure
Oladipupo Anibire, BS1; Hasenin Al-Khersan, MD2; Basil K. Williams Jr, MD2,3
Structural Changes in Acute Macular Neuroretinopathy Revealed With Adaptive Optics Optical Coherence Tomography
Shin Kadomoto, MD, PhD1; Yuki Muraoka, MD, PhD1; Sotaro Ooto, MD, PhD1; Akitaka Tsujikawa, MD, PhD1
Severe Corneal Involvement Associated With Mpox Infection
Serge Doan, MD1,2; Renan Houry, MD1,2; Ioana Cristea, MD3; Boualem Boughar, MD1; Isabelle Cochereau, MD, PhD1,2,4; Eric E. Gabison, MD, PhD1,2,4; Damien Guindolet, MD, PhD1,2
Visualization of Short Posterior Ciliary Artery Insertion Due to Posterior Staphyloma and Myopic Chorioretinal Atrophy
Giovanna Vieira Moreira, MD1; Eduardo Ferrari Marback, PhD2; Ricardo Luz Leitão Guerra, MSc1
Primary Iris Stromal Cyst in a Female Patient Aged 26 Years
Nawras Alhalabi, MD1; Diana Alia, MD1; Ahmad Alhasan, MD, PhD1
Retinal Aneurysms in Myopic Traction Maculopathy
Michael Nguyen, BS1; Glenn Yiu, MD, PhD1
Morgagnian Cataract With Liquified Nuclear Cleft
Jason Fan, MD, PhD1,2; Brian Evan Goldhagen, MD1,2
Optical Coherence Tomography Angiography and Corresponding Histology
Leonardo Bottazzi, MD1,2; Andrea Montesel, MD3; Giuseppe Querques, MD, PhD1,2
Optical Coherence Tomography Angiography and Corresponding Histology—Reply
Andreas Berlin, MD, MS1,2; K. Bailey Freund, MD3,4; Christine A. Curcio, PhD1
Diabetes Medication to Reduce Age-Related Eye Disorders Beyond Glucose Control
Sylvie Feldman-Billard, MD1
Diabetes Medication to Reduce Age-Related Eye Disorders Beyond Glucose Control—Reply
Joëlle E. Vergroesen, MSc1,2; Caroline C.W. Klaver, MD, PhD1,2,3,4,5; Wishal D. Ramdas, MD, PhD1
Is Anti–Vascular Growth Factor Therapy for Retinopathy of Prematurity Associated With Pulmonary Hypertension?
Talkad S. Raghuveer, MD1,2; Rosey E. Zackula, MA2,3; Hayrettin Okut, PhD2,3
Is Anti–Vascular Growth Factor Therapy for Retinopathy of Prematurity Associated With Pulmonary Hypertension?
Ping-Hao Chiang, MS1,2; Ching-Chieh Lin, MS1,2
Is Anti–Vascular Growth Factor Therapy for Retinopathy of Prematurity Associated With Pulmonary Hypertension?
Vasantha H. S. Kumar, MD1
Is Anti–Vascular Growth Factor Therapy for Retinopathy of Prematurity Associated With Pulmonary Hypertension?—Reply
Christopher R. Nitkin, MD1; Troy Richardson, PhD2; Tamorah Lewis, MD, PhD3
Factors Associated With Optic Disc Edema Development During Spaceflight
Ethan Waisberg, MD1; Joshua Ong, MD2; Andrew G. Lee, MD3,4,5,6,7,8,9,10
Factors Associated With Optic Disc Edema Development During Spaceflight—Reply
Laura P. Pardon, OD, PhD1; Brandon R. Macias, PhD2
