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Association of Left Atrial Strain With Ischemic Stroke Risk in Older Adults
Carlo Mannina, MD1,2; Kazato Ito, MD1; Zhezhen Jin, PhD3; Yuriko Yoshida, MD1; Kenji Matsumoto, MD1; Sofia Shames, MD1; Cesare Russo, MD1,4; Mitchell S. V. Elkind, MS, MD5,6; Tatjana Rundek, MS, MD, PhD7,8,9; Mitsuhiro Yoshita, MD10; Charles DeCarli, MD11; Clinton B. Wright, MD12; Shunichi Homma, MD1; Ralph L. Sacco, MS, MD7,8,9; Marco R. Di Tullio, MD1,13
doi : 10.1001/jamacardio.2022.5449
April 2023, Vol 8, No. 4, Pages 305-408
Importance The risk of ischemic stroke is higher among patients with left atrial (LA) enlargement. Left atrial strain (LAε) and LA strain rate (LASR) may indicate LA dysfunction when LA volumes are still normal. The association of LAε with incident ischemic stroke in the general population is not well established.
Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual CarePost Hoc Analysis of the LOOP Randomized Clinical Trial
Søren Zöga Diederichsen, MD, PhD1; Lucas Yixi Xing, MD1; Diana My Frodi, MD1; Emilie Katrine Kongebro, MD1; Ketil Jørgen Haugan, MD, PhD2; Claus Graff, PhD3; Søren Højberg, MD, PhD4; Derk Krieger, MD, PhD5; Axel Brandes, MD, DMSc6,7,8; Lars Køber, MD, DMSc1,9; Jesper Hastrup Svendsen, MD, DMSc1,9
doi : 10.1001/jamacardio.2022.5526
Importance There is increasing interest in heart rhythm monitoring and technologies to detect subclinical atrial fibrillation (AF), which may lead to incidental diagnosis of bradyarrhythmias.
Differences in Ideal Cardiovascular Health Between Sexual Minority and Heterosexual Adults
Billy A. Caceres, PhD, RN1; Yashika Sharma, MPhil, MSN, RN1; Rohith Ravindranath, BS1; Ipek Ensari, PhD2; Nicole Rosendale, MD3; Danny Doan, MPH1; Carl G. Streed, MD, MPH4,5
doi : 10.1001/jamacardio.2022.5660
Importance Research on the cardiovascular health (CVH) of sexual minority adults has primarily examined differences in the prevalence of individual CVH metrics rather than comprehensive measures, which has limited development of behavioral interventions.
Performance of the European Society of Cardiology 0/1-Hour Algorithm With High-Sensitivity Cardiac Troponin T Among Patients With Known Coronary Artery Disease
Nicklaus P. Ashburn, MD, MS1,2; Anna C. Snavely, PhD1,3; James C. O’Neill, MD1; Brandon R. Allen, MD4; Robert H. Christenson, PhD5; Troy Madsen, MD6; Michael R. Massoomi, MD7; James K. McCord, MD8; Bryn E. Mumma, MD, MAS9; Richard Nowak, MD10; Jason P. Stopyra, MD, MS1; Maite Huis in’t Veld, MD11; R. Gentry Wilkerson, MD11; Simon A. Mahler, MD, MS1,12,13
doi : 10.1001/jamacardio.2023.0031
Importance The European Society of Cardiology (ESC) 0/1-hour algorithm is a validated high-sensitivity cardiac troponin (hs-cTn) protocol for emergency department patients with possible acute coronary syndrome. However, limited data exist regarding its performance in patients with known coronary artery disease (CAD; prior myocardial infarction [MI], coronary revascularization, or ≥70% coronary stenosis).
Associations Between Kidney Histopathologic Lesions and Incident Cardiovascular Disease in Adults With Chronic Kidney Disease
Leo F. Buckley, PharmD1; Insa M. Schmidt, MD, MPH2; Ashish Verma, MD2; Ragnar Palsson, MD3; Debbie Adam, BS4; Amil M. Shah, MD, MPH5; Anand Srivastava, MD, MPH6; Sushrut S. Waikar, MD, MPH2
doi : 10.1001/jamacardio.2023.0056
Importance Histologic lesions in the kidney may reflect or contribute to systemic processes that may lead to adverse cardiovascular events.
Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre–Heart Failure With Preserved Ejection FractionThe PARABLE Randomized Clinical Trial
Mark Ledwidge, PhD1,2; Jonathan D. Dodd, MD2,3; Fiona Ryan, PhD1; Claire Sweeney, PhD1; Katherine McDonald, MB1; Rebecca Fox, BSc1; Elizabeth Shorten, BSc1; Shuaiwei Zhou, PhD1; Chris Watson, PhD1,2,4; Joseph Gallagher, MD2; Niall McVeigh, MD2,3; David J. Murphy, MD2,3; Kenneth McDonald, MD1,2
doi : 10.1001/jamacardio.2023.0065
Importance Pre–heart failure with preserved ejection fraction (pre-HFpEF) is common and has no specific therapy aside from cardiovascular risk factor management.
Quality of Care and Outcomes Among Patients Hospitalized for Heart Failure in Rural vs Urban US HospitalsThe Get With The Guidelines–Heart Failure Registry
Jacob B. Pierce, MD, MPH1; Uchechukwu Ikeaba, MS2; Anthony E. Peters, MD2,3; Adam D. DeVore, MD, MHS2,3; Karen Chiswell, PhD2; Larry A. Allen, MD, MHS4; Nancy M. Albert, PhD5; Clyde W. Yancy, MD, MSc6,7; Gregg C. Fonarow, MD8,9; Stephen J. Greene, MD2,3
doi : 10.1001/jamacardio.2023.0241
Importance Prior studies have suggested patients with heart failure (HF) from rural areas have worse clinical outcomes. Contemporary differences between rural and urban hospitals in quality of care and clinical outcomes for patients hospitalized for HF remain poorly understood.
Association of Dapagliflozin Use With Clinical Outcomes and the Introduction of Uric Acid–Lowering Therapy and Colchicine in Patients With Heart Failure With and Without GoutA Patient-Level Pooled Meta-analysis of DAPA-HF and DELIVER
Jawad H. Butt, MD1,2; Kieran F. Docherty, MBChB, PhD1; Brian L. Claggett, PhD3; Akshay S. Desai, MD, MPH3; Magnus Petersson, MD, PhD4; Anna Maria Langkilde, MD, PhD4; Rudolf A. de Boer, MD, PhD5; Adrian F. Hernandez, MD6; Silvio E. Inzucchi, MD7; Mikhail N. Kosiborod, MD8; Lars Køber, MD, DMSc2; Carolyn S. P. Lam, MD9; Felipe A. Martinez, MD10; Piotr Ponikowski, MD, PhD11; Marc S. Sabatine, MD, MPH12; Sanjiv J. Shah, MD13; Muthiah Vaduganathan, MD, MPH3; Pardeep S. Jhund, MBChB, MSc, PhD1; Scott D. Solomon, MD3; John J. V. McMurray, MD1
doi : 10.1001/jamacardio.2022.5608
Importance Gout is common in patients with heart failure (HF), and sodium-glucose cotransporter 2 inhibitors, a foundational treatment for HF, reduce uric acid levels.
Effect of Brief Counseling by Allied Health Professionals on Step Count of People With Peripheral Artery DiseaseA Randomized Clinical Trial
Jonathan Golledge, MChir1,2,3; Lisan Yip, MSc1; Alkira Venn, BExPHys(Clin)1; Anthony S. Leicht, PhD3,4; Jason S. Jenkins, MBBS5; Maria A. Fiatarone Singh, PhD6,7; Christopher M. Reid, PhD8,9; Zanfina Ademi, PhD9,10; Belinda J. Parmenter, PhD11; Joseph V. Moxon, PhD1,3; Nicola W. Burton, PhD12,13,14; for the BIP Investigators
doi : 10.1001/jamacardio.2022.5437
Importance It is unclear how to effectively promote walking in people with peripheral artery disease (PAD).
High-Sensitivity Troponin T and I Among Pregnant Women in the US—The National Health and Nutrition Examination Survey, 1999-2004
Anum S. Minhas, MD, MHS1,2; Justin B. Echouffo-Tcheugui, MD, PhD3; Sui Zhang, MS4; Chiadi E. Ndumele, MD, PhD, MHS1,2,4; J. William McEvoy, MB, BCH, MHS, PhD2,5; Robert Christenson, PhD6; Elizabeth Selvin, PhD, MPH4
A Universal Programmer for Cardiac Implantable Electrical Devices—Clinical, Technical, and Ethical Considerations
Daniel B. Kramer, MD, MPH1,2; Marie E. G. Moe, PhD3; Nicholas S. Peters, MD4,5
Walking Exercise for Peripheral Artery Disease
Mary M. McDermott, MD1
Incidental Detection of Bradycardia by Implantable Loop Recorders—Unintended Consequences
Mark H. Schoenfeld, MD1; Kristen K. Patton, MD2,3
Critical Appraisal of the Negative Predictive Performance of the European Society of Cardiology 0/1-Hour Algorithm for Evaluating Patients With Chest Pain in the US
Júlia Karády, MD1,2; David A. Morrow, MD, MPH3
A Woman With Recurrent Torsade de Pointes
Cody McCoy, MD1; John M. Miller, MD1; Tanyanan Tanawuttiwat, MD, MPH1
A Young Woman With Dyspnea During Cardiac Catheterization
Praveen Gupta, DM1
A Man in His 50s With an Unusual Network of Small Veins in the Left Infraclavicular Region—Paget-Schroetter Syndrome
Elnur Tahirović, MD, PhD1,2; Nermir Granov, MD, PhD1
Native Bypass of the Left Coronary Artery in a Male Patient Aged 63 Years
Vishal K. Narang, MD1; Matthew Budoff, MD, MSSCT2
