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Using the BigMouth repository for periodontal medicine: Breaking the chains?
Muhammad H. A. Saleh, Ann Decker, Hom-Lay Wang
doi : 10.1002/JPER.22-0475
To achieve the ultimate therapeutic reality of disease prevention, we must first conduct a thorough review of periodontal and peri-implant diseases concomitant with their mechanistic, predisposing, and precipitating factors to address the present oral/systemic needs of our patients.
Periodontitis prevalence and severity in inflammatory bowel disease: A case–control study
Giacomo Baima, Mamdouh Muwalla, Giulia Testa, Francesca Mazza, Ahmad Bebars, Stefano Perotto, Marta Vernero, Alessandro Massano, Federica Romano, Davide Giuseppe Ribaldone, Mario Aimetti
doi : 10.1002/JPER.22-0322
Recent evidence is supporting the notion of a microbiological and immunological continuum on the gum–gut axis in health and disease. Therefore, the purpose of this study was to assess the prevalence and risk indicators of periodontitis in patients with Crohn's disease (CD) or ulcerative colitis (UC) compared to age- and sex-matched controls without inflammatory bowel disease (IBD).
Significance of barrier membrane on the reconstructive therapy of peri-implantitis: A randomized controlled trial
Alberto Monje, Ramón Pons, Javi Vilarrasa, José Nart, Hom-Lay Wang
doi : 10.1002/JPER.22-0511
The objective of this trial was to investigate the clinical and radiographic significance of using a mixture of mineralized and demineralized allografts in combination (M) or not (NM) with a resorbable cross-linked barrier membrane in the reconstructive therapy of peri-implantitis defects.
Effect of non-surgical therapy on plasma C-reactive protein levels in patients with periodontitis: A single arm prospective clinical trial
Bansari Shah, Monali Shah, Maria Geisinger, Muhammad H. A. Saleh, Mohamed Meghil, Hom-Lay Wang
doi : 10.1002/JPER.22-0231
This study aimed to evaluate the effect of scaling and root planing (SRP) on levels of plasma C-reactive protein (CRP).
The effect of Er:YAG laser treatment on biofilm formation on titanium and zirconia disc surfaces
Nasser Assery, Nora Alomeir, Yan Zeng, Jin Xiao, Alexandra Tsigarida
doi : 10.1002/JPER.22-0243
Lasers represent a promising method for implant decontamination, but evidence on implant surface changes and subsequent biofilm formation is limited. This study aimed to assess the effect of erbium-doped yttrium aluminum garnet (Er:YAG) laser treatment on zirconia and titanium discs, and the differences in biofilm formation as a result of surface alterations.
Clinical effects of the adjunctive use of polynucleotide and hyaluronic acid-based gel in the subgingival re-instrumentation of residual periodontal pockets: A randomized, split-mouth clinical trial
Andrea Pilloni, Mariana A. Rojas, Cinzia Trezza, Mauro Carere, Alessandro De Filippis, Rosalia L. Marsala, Lorenzo Marini
doi : 10.1002/JPER.22-0225
Polynucleotides (PN) and hyaluronic acid (HA) have been effective in stimulating the growth of primary gingival fibroblasts and promoting wound healing. The aim of this study was to investigate the clinical efficacy of a gel containing PN and HA used in association with subgingival re-instrumentation in the treatment of residual periodontal pockets.
Racial and ethnic disparities in periodontal health among adults seeking dental care in rural North Carolina communities: A retrospective study
Alex Gillone, Acela A. Martinez Luna, Qiang Wu, Gerard Camargo, Mark E. Moss, Ramiro Mendonca Murata, Vanessa Pardi, David W. Paquette
doi : 10.1002/JPER.22-0137
Population studies consistently demonstrate a greater prevalence of chronic diseases, including oral diseases, among underrepresented minorities. This retrospective study aimed to measure and describe the prevalence and extent of periodontitis among adults seeking dental care within an academic practice-based network in rural North Carolina.
Probiotic Lactobacillus rhamnosus EM1107 prevents hyperglycemia, alveolar bone loss, and inflammation in a rat model of diabetes and periodontitis
Davi N. A. Silva, Natália T. S. Cruz, Agnes A. Martins, Régia C. M. Silva, Hursula C. Almeida, HeloÃsa E. S. Costa, Karina M. O. Santos, BasÃlio R. Vieira, Frederico B. Sousa, Francisco S. Junior, Raimundo F. A. Júnior, Gerlane C. B. Guerra, Flavia Q. Pirih, Aurigena A. Araújo, Ana R. L. A. Martins
doi : 10.1002/JPER.22-0262
This study evaluated the antihyperglycemic, anti–bone-resorptive, and anti-inflammatory efficacy of the probiotic Lactobacillus rhamnosus EM1107 in an experimental model of ligature-induced periodontitis in diabetic rats treated with metformin (Met).
Impact of Bifidobacterium animalis subsp. lactis HN019 probiotic in the prevention of periodontitis associated with immunosuppression
Luciana Prado Maia, Yara Loyanne de Almeida Silva Levi, Pedro Henrique Félix Silva, Luana Carla Wons, Livia Pizzo Pitelli, Jéssica Goulart de Castro, Eder da Silva Dólens, Danielle Gregorio, Fabiana Gouveia Straioto, Carolina dos Santos Santinoni, Renato Casarin, Edilson Ervolino, Flávia Aparecida Chaves Furlaneto, Michel Reis Messora
doi : 10.1002/JPER.22-0146
This study evaluated the effects of the probiotic Bifidobacterium animalis subsp. lactis HN019 (HN019) in the development of experimental periodontitis (EP) in rats submitted to chemotherapy (5-fluorouracil [5FU]).
Fusobacterium nucleatum aggravates ulcerative colitis through promoting gut microbiota dysbiosis and dysmetabolism
Shulan Lin, Xiaoyue Zhang, Xuanzhi Zhu, Junwei Jiao, Yafei Wu, Yan Li, Lei Zhao
doi : 10.1002/JPER.22-0205
The correlation between periodontitis and ulcerative colitis (UC) has drawn widespread attention recently. Fusobacterium nucleatum (F. nucleatum) as a periodontal pathogen also has reservoirs in gut and may play a role in intestinal diseases. However, its role in the pathogenesis of UC is unclear.
Biofilm formation, its removal, and consequent effect on the osteoblast response to titanium surfaces: A model for re-osseointegration
Tali Chackartchi, Liana Zaydel, Lior Shapira, Sharon Shany-Kdoshim, David Polak
doi : 10.1002/JPER.22-0142
The aim of the study was to characterize pathogenic biofilm formation on titanium surfaces, the ability to remove the biofilm and the osteoblast response to infected and cleaned titanium surfaces as a model for re-osseointegration.
Immune response characterization of primary gingival fibroblasts from Grade C periodontitis patients
Camila S. Stolf, Catharina M. Sacramento, Carolina A. P. G. Alvarenga, Jonathan R. Vieira, Cássia F. Araújo, Mabelle F. Monteiro, Hélvis E. S. Paz, Mauro P. Santamaria, Karina G. S. Ruiz, Renato C. V. Casarin
doi : 10.1002/JPER.22-0356
Grade C, Stage 3–4 Periodontitis (Perio4C) is a rapidly destructive disease caused by an unequilibrated immune response that starts after the primary contact of the periodontopathogens with the gingival tissue.
Characteristics of mesenchymal stem cells from supracrestal gingival connective tissue
Supreda S. Srithanyarat, Manutsanun Choosiri, Noppadol Sa-Ard-Iam, Pijitra Petcharat, Thanaphum Osathanon
doi : 10.1002/JPER.22-0306
Although periodontal ligament-derived mesenchymal stem cells (PDL-MSCs) have been recognized as the best MSC choice for periodontal regeneration, using PDL-MSCs requires tooth extraction for cell isolation.
