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Integrated Pathologic Score Effectively Stratifies Patients With Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant Therapy and Pancreaticoduodenectomy.
Sohn, Aaron J. MD *; Taherian, Mehran MD *; Katz, Matthew H.G. MD +; Prakash, Laura R. MD +; Chatterjee, Deyali MD *; Wang, Hua MD, PhD ++; Kim, Michael MD +; Tzeng, Ching-Wei D. MD +; Lee, Jeffrey E. MD +; Ikoma, Naruhiko MD +; Rashid, Asif MD, PhD *; Wolff, Robert A. MD ++; Zhao, Dan MD ++; Koay, Eugene J. MD, PhD [S]; Sun, Ryan PhD [//]; Maitra, Anirban MD *; Wang, Huamin MD, PhD *
doi : 10.1097/PAS.0000000000002013
Volume 47(4) pgs. 421-523 April 2023
AB Neoadjuvant therapy is increasingly used to treat patients with pancreatic ductal adenocarcinoma (PDAC). Pathologic parameters of treated PDAC, including tumor (ypT) and lymph node (ypN) stage, and tumor response grading (TRG) are important prognostic factors in this group of patients.
Clinicopathologic Features and Frozen Diagnostic Pitfalls of Bronchiolar Adenoma/Ciliated Muconodular Papillary Tumors (BA/CMPTs).
Ding, Bowen MM; Shang, Zhanxian MM; Xiang, Zhenzhen MM; Han, Yuchen MD, PhD
doi : 10.1097/PAS.0000000000002016
AB To describe the histologic features of bronchiolar adenoma/ciliated muconodular papillary tumors (BA/CMPTs) and analyze the pitfalls in diagnosis from frozen sections.
Strong Annexin A10 Expression Supports a Pancreatic Primary and Combined Annexin A10, Claudin 18, and SOX2 Expression Supports an Esophagogastric Origin in Carcinomas of Unknown Primary.
Isidro, Raymond A. MD, PhD *; Abukhiran, Ibrahim MD +; Dunseth, Craig D. MD ++; Gosse, Matthew D. MD [S]; Humble, Robert M. MD [S]; Pelletier, Daniel J. MD [//]; Varshney, Neha MD [P]; Bellizzi, Andrew M. MD [S]; Hornick, Jason L. MD, PhD *
doi : 10.1097/PAS.0000000000001994
AB Primary tumor site determination for gastrointestinal (GI) tract and pancreaticobiliary (PB) tree carcinomas that present as metastasis of unknown primary can be problematic.
GLI1 Immunohistochemistry Distinguishes Mesenchymal Neoplasms With GLI1 Alterations From Morphologic Mimics.
Parrack, Paige H. MD; Marino-Enriquez, Adrian MD, PhD; Fletcher, Christopher D.M. MD, FRC.Path; Hornick, Jason L. MD, PhD; Papke, David J. Jr MD, PhD
doi : 10.1097/PAS.0000000000002018
AB Glioma-associated oncogene 1 (GLI1) alterations have been described in pericytoma with t(7;12), gastroblastoma, plexiform fibromyxoma, and an emerging class of GLI1-rearranged or amplified mesenchymal neoplasms including "nested glomoid neoplasm".
Nested Subtype of Urothelial Carcinoma in the Upper Urinary Tract: A Series of 15 Cases.
Fatima, Aisha MD *; Russell, Daniel H. MD *; Epstein, Jonathan I. MD *,+,++
doi : 10.1097/PAS.0000000000002008
AB Nested subtype of urothelial carcinoma (NVUC) of the upper urinary tract is rare. While this subtype has an aggressive behavior in the urinary bladder, little is known about this subtype in the renal pelvis and ureter.
Cauda Equina Neuroendocrine Tumors: Distinct Epithelial Neuroendocrine Neoplasms of Spinal Origin.
Asa, Sylvia L. MD, PhD *; Mete, Ozgur MD +; Schuller, Ulrich MD ++; Ramani, Biswarathan MD, PhD [S]; Mirchia, Kanish MD, PhD [S]; Perry, Arie MD [S]
doi : 10.1097/PAS.0000000000002009
AB The tumor formerly known as "cauda equina paraganglioma" was recently renamed as cauda equina neuroendocrine tumor (CENET) based on distinct biological and genetic properties. Nevertheless, it remains insufficiently understood.
Challenges in the Diagnosis of Epstein-Barr Virus-positive Inflammatory Follicular Dendritic Cell Sarcoma: Extremely Wide Morphologic Spectrum and Immunophenotype.
Li, Yan PhD *,+; Yang, Xia MD *,+; Tao, Lili MD, PhD ++; Zeng, Weimei BS [S]; Zuo, Min MD [//]; Li, Shuo MD *,+; Wu, Liyan BS *,+; Lin, Yanshong MD *,+; Zhang, Ziying MD, PhD *,+; Yun, Jingping MD, PhD *,+; Huang, Yuhua MD, PhD *,+
doi : 10.1097/PAS.0000000000002011
AB Epstein-Barr virus (EBV)-positive inflammatory follicular dendritic cell (FDC) sarcoma (EBV+ IFDCS) is a rare entity, and its histopathological characteristics have not been fully described.
Well-differentiated Sertoli-Leydig Cell Tumors (SLCTs) Are Not Associated With DICER1 Pathogenic Variants and Represent a Different Tumor Type to Moderately and Poorly Differentiated SLCTs.
McCluggage, W. Glenn FRCPath *; Rivera, Barbara PhD +,++; Chong, Anne-Sophie PhD +; Clarke, Blaise A. MD [S]; Schultz, Kris Ann P. MD [//]; Dehner, Louis P. MD [P]; Tchrakian, Nairi FRCPath #; Apellaniz-Ruiz, Maria PhD **; Gilks, C. Blake MD ++; Kommoss, Friedrich MD ++++; Stewart, Colin J.R. FRCPA [S][S]; Foulkes, William D. MBBS, PhD [//][//]
doi : 10.1097/PAS.0000000000002010
AB Sertoli-Leydig cell tumors (SLCTs) are uncommon ovarian sex cord-stromal neoplasms which are currently classified into well, moderately, and poorly differentiated and retiform types.
Adenoid Cystic Carcinoma With Striking Tubular Hypereosinophilia: A Unique Pattern Associated With Nonparotid Location and Both Canonical and Novel EWSR1: MYB and FUS: MYB Fusions.
Weinreb, Ilan MD, FRCPC *,+; Rooper, Lisa M. MD ++; Dickson, Brendan C. MD, FRCPC +,[S]; Hahn, Elan MD, FRCPC *,+; Perez-Ordonez, Bayardo MD, FRCPC *,+; Smith, Stephen M. MD *,+; Lewis, James S. Jr MD [//]; Skalova, Alena MD, PhD [P]; Baneckova, Martina MD [P]; Wakely, Paul E. Jr MD #; Thompson, Lester D.R. MD **; Rupp, Niels J. MD ++; Freiberger, Sandra N. MD ++; Koduru, Prasad PhD ++++; Gagan, Jeffrey MD, PhD ++++; Bishop, Justin A. MD ++++
doi : 10.1097/PAS.0000000000002023
AB The classification of salivary gland tumors is ever-evolving with new variants of tumors being described every year. Next-generation sequencing panels have helped to prove and disprove prior assumptions about tumors' relationships to one another, and have helped refine this classification.
Inflammatory and Nested Testicular Sex Cord Tumor: A Novel Neoplasm With Aggressive Clinical Behavior and Frequent EWSR1: ATF1 Gene Fusions.
Acosta, Andres M. MD *; Bridge, Julia A. MD +,++; Dal Cin, Paola S. PhD *; Sholl, Lynette M. MD *; Cornejo, Kristine M. MD [S]; Fletcher, Christopher D.M. MD *; Ulbright, Thomas M. MD [//]
doi : 10.1097/PAS.0000000000002022
AB A subset of malignant testicular sex cord tumors (TSCTs), heretofore interpreted as Sertoli cell tumors, not otherwise specified, exhibits distinctive morphologic features that partially overlap with those of seminoma.
TSC/MTOR-associated Eosinophilic Renal Tumors Exhibit a Heterogeneous Clinicopathologic Spectrum: Several Distinct Entities or a Tumor Family?.
Trpkov, Kiril MD
In Reply: TSC/MTOR-associated Eosinophilic Renal Tumors Exhibit a Heterogeneous Clinicopathologic Spectrum: Several Distinct Entities or a Tumor Family?.
Xia, Qiu-yuan MD, PhD *; Wang, Xiao-tong MD, PhD *; Zhao, Ming MD, PhD +; Rao, Qiu MD, PhD *
Intraductal Adenocarcinoma of the Prostate With Cribriform or Papillary Ductal Morphology: Rare Biopsy Cases Lacking Associated Invasive High-grade Carcinoma.
Kryvenko, Oleksandr N. MD
KLF4 c.A1322C Mutation Is a Consistent and Specific Genetic Feature of Raspberry-like Foveolar-type Adenoma of the Stomach.
Naka, Tomoaki MD, PhD *; Hashimoto, Taiki MD, PhD *; Yoshida, Teruhiko MD, PhD +; Yatabe, Yasushi MD, PhD *,++; Sekine, Shigeki MD, PhD *,++
