New England Journal of Medicine




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On Consolidation and Competition — The Trials and Triumphs of Health Care Antitrust Law

Jaime S. King, J.D., Ph.D.

doi : 10.1056/NEJMp2201629

Vol. 388 No. 12

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Unwinding Continuous Medicaid Enrollment

Sara Rosenbaum, J.D., Sara R. Collins, Ph.D., MaryBeth Musumeci, J.D., and Alex Somodevilla, J.D.

doi : 10.1056/NEJMp2301021

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My Rosalind Franklin Benchmark

Sara C. LaHue, M.D.

doi : 10.1056/NEJMp2214922

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Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression

Eric J. Lenze, M.D., Benoit H. Mulsant, M.D., Steven P. Roose, M.D., Helen Lavretsky, M.D., Charles F. Reynolds, III, M.D., Daniel M. Blumberger, M.D., Patrick J. Brown, Ph.D., Pilar Cristancho, M.D., Alastair J. Flint, M.B., Marie A. Gebara, M.D., Torie R. Gettinger, Ph.D., Emily Lenard, M.S.W., J. Philip Miller, A.B., Ginger E. Nicol, M.D., Hanadi A. Oughli, M.D., Vy T. Pham, M.D., M.P.H., Bruce L. Rollman, M.D., M.P.H., Lei Yang, M.P.H., M.S.I.S., and Jordan F. Karp, M.D.

doi : 10.1056/NEJMoa2204462

The benefits and risks of augmenting or switching antidepressants in older adults with treatment-resistant depression have not been extensively studied.

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Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis

Jonathan I. Silverberg, M.D., Ph.D., M.P.H, Emma Guttman-Yassky, M.D., Ph.D., Diamant Thaçi, M.D., Alan D. Irvine, M.D., Linda Stein Gold, M.D., Andrew Blauvelt, M.D., Eric L. Simpson, M.D., Chia-Yu Chu, M.D., Ph.D., Zhuqing Liu, Ph.D., Renata Gontijo Lima, M.D., Sreekumar G. Pillai, Ph.D., and Julien Seneschal, M.D., Ph.D. for the ADvocate1 and ADvocate2 Investigators*

doi : 10.1056/NEJMoa2206714

Lebrikizumab, a high-affinity IgG4 monoclonal antibody targeting interleukin-13, prevents the formation of the interleukin-4Rα–interleukin-13Rα1 heterodimer receptor signaling complex.

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Acute Effects of Coffee Consumption on Health among Ambulatory Adults

Gregory M. Marcus, M.D., David G. Rosenthal, M.D., Gregory Nah, M.S., Eric Vittinghoff, Ph.D., Christina Fang, B.A., Kelsey Ogomori, B.S., Sean Joyce, Sc.B., Defne Yilmaz, M.S., Vivian Yang, B.A., Tara Kessedjian, Emily Wilson, B.S., Michelle Yang, B.S., Kathleen Chang, B.S., Grace Wall, B.A., and Jeffrey E. Olgin, M.D.

doi : 10.1056/NEJMoa2204737

Coffee is one of the most commonly consumed beverages in the world, but the acute health effects of coffee consumption remain uncertain.

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Covid-19 Surveillance Testing and Resident Outcomes in Nursing Homes

Brian E. McGarry, P.T., Ph.D., Ashvin D. Gandhi, Ph.D., and Michael L. Barnett, M.D.

doi : 10.1056/NEJMoa2210063

Despite widespread adoption of surveillance testing for coronavirus disease 2019 (Covid-19) among staff members in skilled nursing facilities, evidence is limited regarding its relationship with outcomes among facility residents.

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Right Ventricular Failure

Brian A. Houston, M.D., Evan L. Brittain, M.D., and Ryan J. Tedford, M.D.

doi : 10.1056/NEJMra2207410

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Paget’s Disease of the Breast

Rojita Akham, M.B., B.S., and Neirita Hazarika, M.D.

doi : 10.1056/NEJMicm2210124

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Slipped Capital Femoral Epiphysis

Chin-Chean Wong, M.D., Ph.D., and Bing-Kuan Chen, M.D.

doi : 10.1056/NEJMicm2209948

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Case 9-2023: A 20-Year-Old Man with Shortness of Breath and Proteinuria

Shaun F. Fitzgerald, M.D., M.P.H., Teresa Victoria, M.D., Ph.D., Weizhen Tan, M.D., and Cynthia K. Harris, M.D.

doi : 10.1056/NEJMcpc2211356

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Aripiprazole Augmentation in Older Persons with Treatment-Resistant Depression

Gemma Lewis, Ph.D., and Glyn Lewis, Ph.D.

doi : 10.1056/NEJMe2301045

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An mRNA Influenza Vaccine — Could It Deliver?

Kathleen M. Neuzil, M.D., M.P.H.

doi : 10.1056/NEJMcibr2215281

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Neutralization of BQ.1, BQ.1.1, and XBB with RBD-Dimer Vaccines

doi : 10.1056/NEJMc2216233

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Once-Weekly Semaglutide in Adolescents with Obesity

doi : 10.1056/NEJMc2300510

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Efficacy and Safety of Bepirovirsen in Hepatitis B

doi : 10.1056/NEJMc2216469

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New Approaches to Chronic Hepatitis B

doi : 10.1056/NEJMc2301248

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Focused Cardiac Ultrasonography for Right Ventricular Size and Systolic Function

doi : 10.1056/NEJMc2300338

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