Jessica McHughÂÂ
doi : 10.1038/s41584-023-00938-0
Volume 19 Issue 4, April 2023
Sarah OnuoraÂÂ
Jessica McHughÂÂ
Robert PhillipsÂÂ
Robert PhillipsÂÂ
Robert PhillipsÂÂ
Jessica McHughÂÂ
Robert PhillipsÂÂ
Giacomo Emmi & Augusto VaglioÂ
Antonio Pezone, Fabiola Olivieri, Maria Vittoria Napoli, Antonio Procopio, Enrico Vittorio Avvedimento & Armando GabrielliÂ
doi : 10.1038/s41584-022-00905-1
Inflammation is a biological response involving immune cells, blood vessels and mediators induced by endogenous and exogenous stimuli, such as pathogens, damaged cells or chemicals. Unresolved (chronic) inflammation is characterized by the secretion of cytokines that maintain inflammation and redox stress.
Janet E. Pope, Christopher P. Denton, Sindhu R. Johnson, Andreu Fernandez-Codina, Marie Hudson & Tatiana NevskayaÂ
doi : 10.1038/s41584-023-00909-5
Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease with multi-organ involvement, fibrosis and vasculopathy.
Chi Chiu Mok, Y. K. Onno Teng, Ramesh Saxena & Yoshiya TanakaÂ
doi : 10.1038/s41584-023-00925-5
Despite the continuing development of immunomodulatory agents and supportive care, the prognosis associated with lupus nephritis (LN) has not improved substantially in the past decade, with end-stage kidney disease still developing in 5–30% of patients within 10 years of LN diagnosis.
Joshua L. Bennett, Arthur G. Pratt, Richard Dodds, Avan A. Sayer & John D. IsaacsÂ
doi : 10.1038/s41584-023-00921-9
Sarcopenia, a disorder that involves the generalized loss of skeletal muscle strength and mass, was formally recognized as a disease by its inclusion in the International Classification of Diseases in 2016. Sarcopenia typically affects older people, but younger individuals with chronic disease are also at risk.
Theresa Kissel, René E. M. Toes, Thomas W. J. Huizinga & Manfred WuhrerÂ
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