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Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions
Alexis Ceecee Britten-Jones a, Jennifer P. Craig b, Laura E. Downie
doi : 10.1016/j.jtos.2022.10.006
Volume 27, January 2023, Pages 1-12
Corneal nerves play a key role in maintaining ocular surface integrity. Corneal nerve damage, from local or systemic conditions, can lead to ocular discomfort, pain, and, if poorly managed, neurotrophic keratopathy.
A systematic review on the effects of ROCK inhibitors on proliferation and/or differentiation in human somatic stem cells: A hypothesis that ROCK inhibitors support corneal endothelial healing via acting on the limbal stem cell niche
Lloyd R. Kopecny a,*, Brendon W.H. Lee b, Minas T. Coroneo
doi : 10.1016/j.jtos.2022.12.008
Volume 27, January 2023, Pages 16-29
Rho kinase inhibitors (ROCKi) have attracted growing multidisciplinary interest, particularly in Ophthalmology where the question as to how they promote corneal endothelial healing remains unresolved.
Urea and ocular surface: Synthesis, secretion and its role in tear film homeostasis
Swati Singh a,b,c,*, Christian M. Hammer a,d, Friedrich Paulsen
doi : 10.1016/j.jtos.2022.11.003
Volume 27, January 2023, Pages 41-47
Urea has been detected in the tear film, aqueous humor, and vitreous of the eye. While most of the urea in the aqueous humor and vitreous is considered to be an ultrafiltrate from the blood vessels, the presence of urea transporters and urea-synthesizing enzymes in the lacrimal gland, meibomian glands, conjunctiva, and cornea suggests ureagenesis occurring at the ocular surface.
Face mask use and effects on the ocular surface health: A comprehensive review
Barbara Burgos-Blasco a,*, Pedro Arriola-Villalobos a,b, Jose Ignacio Fernandez-Vigo a, Carlos Oribio-Quinto a, Mayte Ari ̃no-Gutierrez a, David Diaz-Valle a,b, Jose Manuel Benitez-del-Castillo
doi : 10.1016/j.jtos.2022.12.006
Volume 27, January 2023, Pages 56-66
In the COVID-19 period, face masks increased exponentially. Several studies suggest that the rise in ocular discomfort symptoms during the pandemic is mostly part of dry eye disease and that these are due to the effect of face masks, resulting in the newly described term MADE, for “mask-associated dry eye�.
Management of scleral melt
Bennett E. Ahearn, Kathryn E. Lewis, Blair E. Reynolds, Ahmad Kheirkhah
doi : 10.1016/j.jtos.2022.12.005
Volume 27, January 2023, Pages 92-99
Scleral melting, while rare, can lead to significant ocular morbidity. Several possible risk factors for scleral melt have been identified, such as infection, autoimmune disease, trauma, and post-surgical state, and these may act in combination with each other.
Monkeypox and ocular implications in humans
Faye Yu Ci Ng a, Steven Yeh b,c,d, Derrick Smit e, Oon Tek Ng f,g,h, Shawn Vasoo f,g,h, Andre Luiz Land Curi i, Rupesh Agrawal
doi : 10.1016/j.jtos.2022.10.005
Volume 27, January 2023, Pages 13-15
Modulation of ocular surface desiccation in a murine model by histatin-5 application
Marwan Ali a, Dhara Shah a, Terry G. Coursey b, Sang Min Lee a, Arun Balasubramaniam a, Tejabhiram Yadavalli a, Deepak Edward a, Kyung-No Son a, Deepak Shukla c, Vinay Kumar Aakalu
doi : 10.1016/j.jtos.2022.12.004
Volume 27, January 2023, Pages 30-37
To determine the efficacy of Histatin-5 (Hst5) peptide treatment in ameliorating dry eye disease (DED) phenotype in an in-vivo mouse model of scopolamine and desiccating stress (SDS) dry eye.
Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency
Michael Mimouni a,b, Edward Cole c, S. Joseph Kim c, Jeffrey Schiff c, Carl Cardella c, Kathryn J. Tinckam c, Allan R. Slomovic a, Clara C. Chan
doi : 10.1016/j.jtos.2022.11.002
Volume 27, January 2023, Pages 48-53
To report outcomes of keratolimbal allograft (KLAL) compatible for both human leukocyte (HLA) and/or blood type using oral prednisone, mycophenolate, and tacrolimus, with basiliximab if panel reactive antibodies (PRA) are present. Intravenous immunoglobulin (IVIG) was used post-operatively if donor-specific anti-HLA antibodies (DSA) were present.
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study
Adam Wylegala a,b, Wathanee Sripawadkul a,c, Mike Zein a, Osmel P. Alvarez a, Ghada Al Bayyat a, Anat Galor a,d, Carol L. Karp
doi : 10.1016/j.jtos.2022.12.002
Volume 27, January 2023, Pages 67-74
To determine the efficacy and safety of topical 1% 5-fluorouracil (5FU) eye drops as primary treatment of ocular surface squamous neoplasia (OSSN).
Maximal tear secretion evoked by controlled stimulation of corneal sensory nerves in healthy individuals and dry eye subjects
MarÃa L. Merino a,b, Javier Belmonte c, Jos Ì�e Rosas d, M. Carmen Acosta a, Juana Gallar a,e, Carlos Belmonte a
doi : 10.1016/j.jtos.2022.11.005
Volume 27, January 2023, Pages 80-88
To measure, the tear flow changes evoked in healthy subjects and dry eye disease (DED) patients by controlled sensory stimulation of the eye surface with i-Onionâ„¢, a new stimulation device.
Apolipoprotein A1 is associated with meibomian gland dropout
Haozhe YuWeizhen ZengWenyan ZhouYun Feng
doi : 10.1016/j.jtos.2022.12.003
Volume 27, January 2023, Pages 38-40
Seeing the unseen: Use of a modified OSDI questionnaire to accurately detect chronic ocular GVHD in a hematology clinic
E. GreenanE. Vandenberghe, E. ConneallyC.C. Murphy
doi : 10.1016/j.jtos.2022.12.001
Volume 27, January 2023, Pages 75-76
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining☆
Matias SoiferNadim S. AzarRicardo BlancoHazem M. MousaArianna TovarPriyatham S. MettuMichael J. AllinghamScott W. CousinsAlfonso L. SabaterVictor L. Perez
doi : 10.1016/j.jtos.2022.11.010
Volume 27, January 2023, Pages 77-79
Association of trachoma with vision-related quality of life in children
Taher K. Eleiwa, Ibrahim A. ElsaadaniAbdelrahman M. Elhusseiny
doi : 10.1016/j.jtos.2022.11.001
Volume 27, January 2023, Pages 89-91
Readership awareness series - Paper 2: Conflict of interest
Mohammad Javed AliAli Djalilian
doi : 10.1016/j.jtos.2022.11.004
Volume 27, January 2023, Pages 54-55
Tools of the cornea specialist
Gary D. Novack a,b,*, Mark J. Mannis
doi : 10.1016/j.jtos.2022.11.006
Volume 27, January 2023, Pages 100-101
Psychological distress in patients with ocular graft-versus-host disease after hematopoietic stem cell transplantation
Yinglin Liao, Jing Li, Wenxin Zhao, Jing Yang, Ziyan Chen,Fen HuangLingyi Liang
doi : 10.1016/j.jtos.2022.11.009
Volume 27, January 2023, Pages 102-104
