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Various aspects of the relationship between vitiligo and the COVID-19 pandemic or SARS-CoV-2 vaccines: Clinical pearls for dermatologists
Zeinab Aryanian MD, Kamran Balighi MD, Parvaneh Hatami MD, Azadeh Goodarzi MD, Alireza Janbakhsh MD, Zeinab Mohseni Afshar MD
doi : 10.1111/jocd.15550
Coronavirus disease 2019 (COVID-19) has given rise to several new onset or exacerbated dermatologic disorders including vitiligo.
Oral tranexamic acid in the treatment of hyperpigmentation disorder beyond melasma: A review
Taghreed Tariq Mahjoub MD, Heba Hamza Milibary MD
doi : 10.1111/jocd.15561
Tranexamic acid, a synthetic derivative of the amino acid lysine, is an antifibrinolytic, procoagulant agent approved by the Food and Drug Administration for the treatment of cyclic heavy menstrual bleeding and prevention of bleeding in patients with hemophilia undergoing tooth extraction.
Artificial intelligence in Dermatopathology
Shishira R. Jartarkar MD, Clay J. Cockerell MD, Anant Patil MD, Martin Kassir MD, Mahsa Babaei MD, Beate Weidenthaler-Barth MD, Stephan Grabbe MD, Mohamad Goldust MD
doi : 10.1111/jocd.15565
Ever evolving research in medical field has reached an exciting stage with advent of newer technologies. With the introduction of digital microscopy, pathology has transitioned to become more digitally oriented speciality.
Efficacy and safety of topical agents in the treatment of melasma: What's evidence? A systematic review and meta-analysis
Yu-Feng Chang MD, Tai Lin Lee MD, Oyetewa Oyerinde MD, Seemal R. Desai MD, Ali Aljabban MD, Camden P. Bay PhD, Paul A. Bain PhD, Hye Jin Chung MD, MMSc
doi : 10.1111/jocd.15566
Various topical agents have been used to treat melasma; however, a large-scale evaluation among the currently available treatment is lacking.
Energy-based devices in the treatment of acne scars in skin of color
Shereen Teymour DO, Barbara Kania BS, Karan Lal DO, David Goldberg MD
doi : 10.1111/jocd.15572
Acne scarring is disfiguring and psychologically taxing on patients. Many energy-based modalities have emerged and been studied for the treatment of acne scarring; however, there is a paucity of these studies in skin phototypes IV–VI.
The impact of blue light and digital screens on the skin
Jyoti Kumari MBBS, MD, Kinnor Das MD, Mahsa Babaei MD, Ghasem Rahmatpour Rokni MD, Mohamad Goldust MD
doi : 10.1111/jocd.15576
The skin is frequently subjected to a variety of environmental trauma and stress. It is unavoidably subjected to blue light due to the increased use of electronic equipment, including indoor lighting and digital gadgets like smartphones and laptops, which have a range of detrimental effects. The method of action and numerous harmful consequences of blue light on the skin are the main subjects of this review.
Topical management of acne scars: The uncharted terrain
Chingshubam Bikash MD Dermatology, Rashmi Sarkar MD Dermatology
doi : 10.1111/jocd.15584
Scarring is a common but difficult to manage consequence of acne vulgaris. The intricate balance between the degradation of collagen and its inhibition is disturbed during the formation of acne scars.
Tranexamic acid in melasma: A focused review on drug administration routes
Hailey Konisky BS, Eliza Balazic BS, Jose A. Jaller MD, Urmi Khanna MD, Kseniya Kobets MD, MHS
doi : 10.1111/jocd.15589
Melasma is a disorder of hyperpigmentation and vascularization often found in women between the ages of 20 and 40. The pathogenesis is unknown, but melasma often occurs in sun-exposed areas of the face, forearms, and back.
Skin and soft tissue infection of Nontuberculous mycobacterium after injection lipolysis
Yi Yang PhD, Shiyi Li PhD, Lixia Zhang PhD, Huijuan Fu MD, Guiwen Zhou MD, Minliang Chen PhD
doi : 10.1111/jocd.15591
Injection lipolysis is used for body and face contouring due to its minimal invasiveness and cost-effectiveness, but related complications such as nontuberculous mycobacterium infection significantly affect its clinical application.
Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway
Wenqing Zhu MM, Chengzhi Dong MM
doi : 10.1111/jocd.15571
Poly-L-Lactic Acid (PLLA) is a synthetic polymer which possesses biocompatible and biodegradable properties, and is widely used in the clinical filler material. This study focuses on the potential role of PLLA on the collagen production of dermal fibroblasts and its mechanism.
Topical gel containing Polysiloxanes and hyaluronic acid for skin scar: Formulation design, characterization, and In vivo activity
Md. Shoaib Alam, Arif Ansari, Iftikhar Ahsan, Sheikh Shafiq-un-Nabi, Shadab Md, Rasheed A. Shaik, Basma G. Eid, Mohammad Zaki Ahmad, Javed Ahmad
doi : 10.1111/jocd.15574
Scar formation is undesirable both cosmetically and functionally. It shows that silicone gel is effective in preventing and improving scars formed due to a wound formation after injury.
Novel management of granuloma formation secondary to dermal filler: A multi-modality approach
Alexandra Bowles DO, Sabrina Ghalili BS, Oben B. Ojong DO, Gabriella F. Vasile DO, Yumeng M. Li MD, MS, Shino Bay Aguilera DO
doi : 10.1111/jocd.15579
Dermal fillers for soft tissue augmentation have become increasingly popular among patients of all ages and ethnicities. With more widespread use, there has been an increased incidence of adverse reactions, one of which is the granulomatous foreign body reaction (GFBR).
Tranexamic acid microinjections versus tranexamic acid mesoneedling in the treatment of facial melasma: A randomized assessor-blind split-face controlled trial
Nazila Poostiyan MD, Maryam Alizadeh MD, Zabihollah Shahmoradi MD, Farahnaz Fatemi Naeini MD
doi : 10.1111/jocd.15580
Melasma is a hyperpigmentary disorder causing cosmetic disfigurement. We aimed to compare the efficacy and safety of tranexamic acid (TXA) microinjections with TXA mesoneedling for facial melasma.
Infraorbital mass long after dermal filler injection: A report of two cases
Ceyhun Arici MD, Zeynep Tosuner MD
doi : 10.1111/jocd.15583
Hyaluronic acid fillers have been increasingly used throughout the world in the management of aging skin in the periocular region and other areas.
Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study
Rehab Mohammed Salem MD, Sarah Abd Elmordy Salah MBBcH, Samah Ezzat Ibrahim MD
doi : 10.1111/jocd.15590
Enlarged facial pores and seborrhea are common cosmetic problems. Mesobotox has been proved to be effective safe therapeutic option.
Evaluation of botulinum toxin type A for treating post burn hypertrophic scars and keloid in children: An intra-patient randomized controlled study
Abeer Attia Tawfik MD, PhD, Rama Ahmad Ali MD
doi : 10.1111/jocd.15634
Consequently, the management of post burn hypertrophic scars and keloid in children are a great challenge for the physicians, parents, and children themselves.
Novel laser hair removal in all skin types
Michael H. Gold MD, Eduardo Weiss MD, Julie Biron BSc
doi : 10.1111/jocd.15674
Laser has been long accepted as a solution for excess or unwanted hair growth yet traditional lasers are not always ideal for safe and effective outcome for all skin types and hair characteristics
Electromagnetic field for supramaximal muscle stimulation: A retrospective study of safety, efficacy, and patient satisfaction in Brazil
Estela Sant'Ana PhD, Michelle Meleck BSc, Priscila Ferrari PT, Rogerio Padovan MD, Carla Camargo BSc, Silvana Godoi BSc, LÃvia de Assis PhD
doi : 10.1111/jocd.15606
Currently, even individuals who do physical activity regularly have some degree of dissatisfaction with their own bodies. The electromagnetic field for supramaximal muscle contraction has been the subject of research.
Blue light-emitting diodes for the treatment of localized vitiligo: A retrospective study
Giuseppe Lodi MD, Chiara Del Re MD, Steven Paul Nisticò MD, PhD, Luigi Bennardo MD, Giovanni Cannarozzo MD, Mario Sannino MD
doi : 10.1111/jocd.15567
Vitiligo is an autoimmune dermatological disease characterized by hypopigmented macules.
A comparative study of pain perception during the microfocused ultrasound procedure between topical anesthesia and combined topical anesthesia with forced air cooling
Vasanop Vachiramon MD, Pasita Palakornkitti MD, Tanaporn Anuntrangsee MD, Suthinee Rutnin MD, Yingluck Visessiri MD, Sabrina Fabi MD
doi : 10.1111/jocd.15568
The experience of pain during microfocused ultrasound with visualization (MFU-V) treatment is common and crucial for dictating patient satisfaction and retention.
Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized trial
Mona S. Ali MD, Hala S. A. Hafiz MD, Naglaa A. Ahmed MD, Sara Ahmed Galal MD
doi : 10.1111/jocd.15569
Alopecia areata (AA) is a challenging disease with variable treatment outcomes. Hair follicles express vitamin D receptors. Therefore, vitamin D3 may be promising for AA treatment through immunomodulatory mechanisms. The efficacy of bimatoprost in scalp AA treatment was reported by few studies.
Comparative evaluation of the efficacy of topical tacrolimus 0.03% and topical calcipotriol 0.005% mixed with betamethasone dipropionate versus topical clobetasol 0.05% in treatment of alopecia areata: A clinical and trichoscopic study
Amany Nassar MD, Mona Elradi MD, Mona Radwan MSc, Waleed Albalat MD
doi : 10.1111/jocd.15558
Alopecia areata (AA) is a common non-scarring hair loss disorder that affects children and adults with a great psychological burden because of its recurrent and sometimes treatment-refractory nature.
Contour first�retrospective study of an algorithmic approach of auricular keloids
Huanhuan Wu MD, Guoxuan Dong MD, Jintian Hu MD, Meng Wang MD, Yue Liu MD, Chunan Qu MD, Qian Jin MD, Lianzhao Wang MD
doi : 10.1111/jocd.15554
Novel conformation of hyaluronic acid with improved cosmetic efficacy
Geewoo Nam PhD, Hye Won Lee Highschool Diploma, JiSung Jang MS, Chul Hwan Kim PhD, Kyoung-Hee Kim PhD
doi : 10.1111/jocd.15555
Hyaluronic acid presents a valuable cosmetic ingredient that occurs naturally. Its direct links to skin aging has led to its broad application. The aim of this study was to improve the cosmetic efficacy of high molecular weight hyaluronic acid (HMWHA) without chemical modifications and evaluate such improvements through clinical and in vitro studies.
Ultra-minimal pinhole blepharoplasty: A minimally invasive technique for the correction of eyelid bags
Haicheng Yu BA, Liming Ren BA, Yi Zou MD, Ying Guo BA, Haijun Zhu MD, Weiming Qiu PhD, Kai Xu MD
doi : 10.1111/jocd.15557
The aim of the study was to investigate the efficacy and complications of ultra-minimal pinhole blepharoplasty in the treatment of eyelid bags.
Platelet-rich plasma protects human keratinocytes from UVB-induced apoptosis by attenuating inflammatory responses and endoplasmic reticulum stress
Guang-Hua Duan BS, Zhao-Qi Ren MD, Bin Du BS, Wen Shao BS, Hai-Jiao Dong BS, Ai-Cui Du BS
doi : 10.1111/jocd.15559
Although the role of platelet-rich plasma (PRP) in ultraviolet light B (UVB)-induced photoaging has been confirmed in many studies, the specific mechanism is still not clear. Therefore, we attempted to investigate the effect and mechanism of PRP on UVB-induced human keratinocyte (HaCaT cells) apoptosis.
Analysis of images supplied by Skincam® can record the changes of some scar features that occur over time. Comparisons with the assessments of dermatologist and patients' perception
Aurelie Maudet BSc, Jessica Le Bec BSc, Frederic Flament PhD, Laureen Mirassou BSc, Johanna Caron BSc, Caroline Negre BSc, Caroline Delaunay BSc, Guive Balooch PhD, Eunjoo Jang MD
doi : 10.1111/jocd.15575
The objective of the study was to assess in vivo the validity of a new imaging device in quantifying the scarring process over time and to compare its data with the expertise of dermatologist and patients' self-appraisals.
A comparative clinico-dermoscopic study of intralesional injection of combined digoxin and furosemide, Candida antigen, and vitamin D3 for multiple warts
Mohamed Nasr MD, Sara Abdelaty Msc, Basma M. Elkholy MD
doi : 10.1111/jocd.15581
Immunostimulatory and antiproliferative therapies have been widely used for the treatment of multiple warts. Recently, anti-HPV activity of ionic contra viral therapy (ICVT) which is comprised of combined digoxin and furosemide has been demonstrated.
Serum and salivary adipsin levels and its association with insulin resistance in acne vulgaris patients
Kawther Albalwa MSc, Mohammed Kenawy MD, Asmaa Adel El-fallah MD, Rehab Mohammed Salem MD
doi : 10.1111/jocd.15545
There is scarcity in literature about the reliability of salivary markers in acne vulgaris.
Lactoferrin regulates sebogenesis and inflammation in SZ95 human sebocytes and mouse model of acne
Yuan-Ting Su MS, Christos C. Zouboulis PhD, Wei Cui BA, An-Ping Zhang MD
doi : 10.1111/jocd.15577
The aim of this study was to explore the anti-inflammatory and anti-lipid effects of lactoferrin on SZ95 human sebaceous gland cells and mouse model of acne.
Modulation of TRPV1 function by Citrus reticulata (tangerine) fruit extract for the treatment of sensitive skin
Li-dan Zhou MSc, Yi-na Lu MSc, Qing Liu PhD, Xue-mei Shi BSc, Jun Tian MSc
doi : 10.1111/jocd.15578
Claudin-3 is a novel intestinal integrity marker in patients with alopecia areata: Correlation with the disease severity
Dina Rafik MBBCh, Ihab Younis MD, Rana Atef MD, Hanaa Eid MD
doi : 10.1111/jocd.15582
The development of alopecia areata is suggested to be influenced by intestinal permeability and gut dysbiosis. Claudin-3, an essential component of tight junctions which may act as an indicator of intestinal barrier integrity.
EGCG inhibits hypertrophic scar formation in a rabbit ear model
Yajuan Song MD, Tong Wang MD, Liu Yang MD, Junzheng Wu MD, Lin Chen MD, Xiao Fan MD, Zhe Zhang MD, Qing Yang MD, Zhou Yu PhD, Baoqiang Song PhD
doi : 10.1111/jocd.15587
Hypertrophic scarring is a common skin fibro-proliferative disease, but currently there has no satisfactory drugs for anti-scar treatments. Previous study showed that epigallocatechin gallate (EGCG), the main catechin in green tea, improved wound healing and tissue fibrosis in both rats and mice.
Biochemical and hormonal abnormalities in adult female acne
Amit Kumar Meena MD, Vibhu Mendiratta MD, Rajeev Goyal MD, Kavita Bisherwal MD, Vidya Yadav MD, Vivin Prasadh MD
doi : 10.1111/jocd.15588
Prevalence of adult patients with acne is increasing and women comprise majority of the cases. There is lack of data on biochemical and hormonal abnormalities in adult female acne (AFA).
A prospective randomized controlled study of Mycobacterium Indicus Pranii vaccine, Measles Mumps Rubella vaccine and Vitamin D3 in extragenital cutaneous warts
Utkrist Lahoria MD, Saurabh Singh MD, DNB, Abhishek Bhardwaj MD, Anil Budania MD, Neelam Chhajed MD, Srinivasan Varun Rajagopal MD, Surjit Singh MD, DM
doi : 10.1111/jocd.15564
Outpatient department, Department of Dermatology, Venereology and Leprology, AIIMS Jodhpur (Rajasthan), India.
Adult-onset Still's disease presenting with “pencil sketch-like� arrangement of papules and geographic pigmentation
Farzana Ansari MD, DNB, Utkrist Lahoria MD, Mohammad Nadeem MD, Sudeep Khera MD, Saurabh Singh MD, DNB
doi : 10.1111/jocd.15547
Cosmetic dermatology services in metaverse
Mahsa Babaei MD, Hassan Galadari MD, Michael H. Gold MD, Mohamad Goldust MD
doi : 10.1111/jocd.15670
Response of chronic refractory psoriasis vulgaris with urticaria to combined secukinumab and omalizumab: A case report and review of the literature
Ayman Abdelmaksoud MSc, Selami Aykut Temiz MD, Munise Daye MD, Sibel Yavuz MD, Uwe Wollina MD, Torello Lotti MD, Recep Dursun MD
doi : 10.1111/jocd.15551
A novel subcision technique for effective treatment of depressed facial scars
Zehui Li MM, Jintian Hu MD, Xueshang Su MM, Ximeng Jia MM, Yueheng Zhu BM
doi : 10.1111/jocd.15552
Dermoscopy guided thermolysis�A modification to improve ease of procedure
Tejas Vishwanath MD, Satish Udare MD, Shweta Rajput MD, Vishalakshi Viswanath MD
doi : 10.1111/jocd.15553
Assessing the risk of anxiety in patients with pemphigus vulgaris using Beck Anxiety Inventory
Zeinab Aryanian MD, Keyhan Omidi MD, Hamidreza Mahmoudi MD, Yousef Fakour MD, Ifa Etesami MD, Azadeh Goodarzi MD, Parvaneh Hatami MD
doi : 10.1111/jocd.15585
“Chemical Peel Recipe��An easy and quick method of peel preparation in resource-limited settings
Siddhi B. Chikhalkar MD, Tejas Vishwanath MBBS, MD, DVL, Aditi Ajay Shende MD
doi : 10.1111/jocd.15592
Erratum to “Cutaneous manifestations of coronavirus disease 2019â€Â� by Ghafoor, Ali, and Goldust (2022)â€Â
doi : 10.1111/jocd.15656
