Pediatric Allergy and Immunology




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Issue Information

doi : 10.1111/pai.13793

Volume 34, Issue 4

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Editorial comment on: Diet-associated vertically transferred metabolites and risk of asthma, allergy, eczema, and infections in early childhood

Beatriz Moya, Carmen Riggioni, Ã–mer Kalayci, Philippe Eigenmann

doi : 10.1111/pai.13947

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Early-life environment and the risk of eczema at 2 years�Meta-analyses of six Finnish birth cohorts

Minna Lukkarinen, Pirkka V. Kirjavainen, Katri Backman, Carlos Gonzales-Inca, Brandon Hickman, Sampo Kallio, Hasse Karlsson, Linnea Karlsson, Leea Keski-Nisula, Laura S. Korhonen, Katri Korpela, Mikael Kuitunen, Anna Kaarina Kukkonen, Niina Käyhkö, Hanna Lagström, Heikki Lukkarinen, Ville Peltola, Jaana Pentti, Anne Salonen, Erkki Savilahti, Pauli Tuoresmäki, Martin Täubel, Jussi Vahtera, Willem M. de Vos, Juha Pekkanen, Anne M. Karvonen

doi : 10.1111/pai.13945

Urban-related nature exposures are suggested to contribute to the rising prevalence of allergic diseases despite little supporting evidence. Our aim was to evaluate the impact of 12 land cover classes and two greenness indices around homes at birth on the development of doctor-diagnosed eczema by the age of 2 years, and the influence of birth season.

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Cost-effectiveness of omalizumab for the treatment of severe pediatric allergic asthma�Results of a real-life study in Spain

María Nieto-Cid, Teresa Garriga-Baraut, Ana Mª. Plaza-Martín, Miguel Tortajada-Girbés, Javier Torres-Borrego, Jaime Lozano-Blasco, Laura Moreno-Galarraga, Mª. del Mar Folqué-Giménez, Montse Bosque-García, Mirella Gaboli, Alejandro López-Neyra, Cristina Rivas-Juesas, Mª. Araceli Caballero-Rabasco, Andrea Freixa-Benavente, Laura Valdesoiro-Navarrete, Inés de Mir-Messa, Esther Ballester-Asensio, María Penín-Antón, Raquel Romero-García, Juan Navarro-Morón, Alfredo Valenzuela-Soria, Mercedes Sánchez-Mateos, José Batlles-Garrido, Verónica Sanz-Santiago, Ã�lvaro Gimeno-Díaz de Atauri, Anselmo Andrés-Martín, Elena Campos-Alonso, David Gómez-Pastrana, Elena Vázquez-Rodríguez, Luz Martínez-Pardo, Genoveva del Río-Camacho, Ã�ngel Mazón-Ramos, Antonio Nieto-García

doi : 10.1111/pai.13942

Severe pediatric allergic asthma (SPAA) induces a huge economic burden in terms of direct, indirect, and intangible costs. The use of omalizumab for the treatment of these patients has produced a significant improvement in several clinical outcomes, but at the same time, the cost for the management of the disease has also increased.

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Clinical and genetic characterization of Netherton syndrome due to SPINK5 founder variant in Latvian population

Inga Nartisa, Rasa Kirsteina, Katrina Daila Neiburga, Sanita Zigure, Lota Ozola, Ineta Grantina, Ieva Micule, Daiga Murmane, Baiba Slisere, Linda Gailite, Baiba Vilne, Dmitrijs Rots, Gita Taurina, Natalja Kurjane

doi : 10.1111/pai.13937

Netherton syndrome (NS) (OMIM:256500) is a very rare autosomal recessive multisystem disorder mostly affecting ectodermal derivatives (skin and hair) and immune system. It is caused by biallelic loss-of-function variants in the SPINK5 gene, encoding the protease inhibitor lymphoepithelial Kazal-type-related inhibitor (LEKTI).

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Hyper-IgE syndrome presenting with early life craniosynostosis in monozygotic twin sisters

Anna Peirolo, Charlotte Verolet, Emmanuelle Ranza, Marie Rohr, Meryle Laurent, Isabelle Ruchonnet-Metrailler, Austen J. J. Worth, Geraldine Blanchard-Rohner

doi : 10.1111/pai.13944

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Experiences of caregivers of children with food allergy during the COVID-19 pandemic

Caroline M. Roberts, Taylor M. Dattilo, Shahan Stutes, Dean Atkinson, Carrick Carter, Jessica MacDougall, Yamini V. Virkud, Larry L. Mullins, Alayna P. Tackett

doi : 10.1111/pai.13946

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Early childhood allergy prevention behaviors: Trends in Germany from 2015 to 2020

Maja Pawellek, Angela Köninger, Michael Melter, Michael Kabesch, Christian Apfelbacher, Susanne Brandstetter, KUNO-Kids study group

doi : 10.1111/pai.13948

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