One-year access to more than 500 world journals available in the system
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The American Academy of Neurology at 75: Inclusivity and Evolution.
Avitzur, Orly MD, MBA; Streeter, Timothy S. MA
doi : 10.1212/WNL.0000000000206997
The American Academy of Neurology at 75: Inclusivity and Evolution.
Blood Pressure and Risk of Dementia in Parkinson Disease and Multiple System Atrophy: Should You Buy the Dip in Such a Volatile Market?.
Palma, Jose-Alberto MD, PhD, FAAN; Cortelli, Pietro MD, PhD
Climate Change and Air Pollution: Neurologists Should Educate Themselves and Get Involved.
Junck, Larry MD; Malow, Beth A. MD, MS
Association Between Orthostatic Hypotension and Dementia in Patients With Parkinson Disease and Multiple System Atrophy.
Ruiz Barrio, Inigo MD; Miki, Yasuo MD, PhD; Jaunmuktane, Zane T. MD; Warner, Thomas PhD, FRCP; De Pablo-Fernandez, Eduardo MD, PhD
doi : 10.1212/WNL.0000000000201659
Orthostatic hypotension (OH) increases dementia risk in patients with Parkinson disease (PD), although the underlying mechanisms and whether a similar association between OH and cognitive impairment exists in other synucleinopathies remain unknown.
CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease.
Kurihara, Masanori MD, PhD; Komatsu, Hiroki MD; Sengoku, Renpei MD, PhD; Shibukawa, Mari MD; Morimoto, Satoru MD, PhD; Matsubara, Tomoyasu MD; Arakawa, Akira MD; Orita, Makoto DDS; Ishibashi, Kenji MD, PhD; Mitsutake, Akihiko MD; Shibata, Shota MD, PhD; Ishiura, Hiroyuki MD, PhD; Adachi, Kaori PhD; Ohse, Kensuke PhD; Hatano, Keiko MD, PhD; Ihara, Ryoko MD, PhD; Higashihara, Mana MD, PhD; Nishina, Yasushi MD; Tokumaru, Aya Midori MD, PhD; Ishii, Kenji MD; Saito, Yuko MD, PhD; Murayama, Shigeo MD, PhD; Kanemaru, Kazutomi MD, PhD; Iwata, Atsushi MD, PhD
doi : 10.1212/WNL.0000000000201647
CSF tau phosphorylated at threonine 181 (p-tau181) is a widely used biomarker for Alzheimer disease (AD) and has recently been regarded to reflect [beta]-amyloid and/or p-tau deposition in the AD brain.
Association of Subjective Cognitive Decline With Progression to Dementia in a Cognitively Unimpaired Multiracial Community Sample.
Chapman, Silvia PhD; Renteria, Miguel Arce PhD; Dworkin, Jordan D. PhD; Garriga, Stella M. BS; Barker, Megan S. PhD; Avila-Rieger, Justina PhD; Gonzalez, Christopher MS; Joyce, Jillian L. MS; Vonk, Jet M.J. PhD; Soto, Elizabeth BS; Manly, Jennifer J. PhD; Brickman, Adam M. PhD; Mayeux, Richard P. MD; Cosentino, Stephanie A. PhD
doi : 10.1212/WNL.0000000000201658
This prospective study seeks to examine the utility of subjective cognitive decline (SCD) as a marker of future progression to dementia in a community-based cohort of non-Latinx White, non-Latinx Black, and Latinx individuals.
Economic Evaluation of the Community Benefit of the Australian Pregnancy Register of Antiseizure Medications.
Ademi, Zanfina MPharm, MPH, PhD; Marquina, Clara PhD; Perucca, Piero MD, PhD; Hitchcock, Alison BSN; Graham, Janet BSN; Eadie, Mervyn J. PhD; Liew, Danny PhD; O'Brien, Terence J. MD; Vajda, Frank J. MD
doi : 10.1212/WNL.0000000000201655
The Raoul Wallenberg Australian Pregnancy Register (APR) was established to collect, analyze, and publish data on the risks to babies exposed to antiseizure medications (ASMs) and to facilitate quality improvements in management care over time.
Neurologic Improvement in Acute Cerebral Ischemia: Frequency, Magnitude, Predictors, and Clinical Outcomes.
Balucani, Clotilde MD, PhD; Levine, Steven R. MD; Sanossian, Nerses MD; Starkman, Sidney MD; Liebeskind, David MD; Gornbein, Jeffrey A. DrPH; Shkirkova, Kristina BS; Stratton, Samuel MD; Eckstein, Marc MD; Hamilton, Scott PhD; Conwit, Robin MD; Sharma, Latisha K. MD; Saver, Jeffrey L. MD
doi : 10.1212/WNL.0000000000201656
Investigations of rapid neurologic improvement (RNI) in patients with acute cerebral ischemia (ACI) have focused on RNI occurring after hospital arrival. However, with stroke routing decisions and interventions increasingly migrating to the prehospital setting, there is a need to delineate the frequency, magnitude, predictors, and clinical outcomes of patients with ACI with ultra-early RNI (U-RNI) in the prehospital and early postarrival period.
Association Between Statin Use and Intracerebral Hemorrhage Location: A Nested Case-Control Registry Study.
Boe, Nils Jensen MD; Hald, Stine Munk MD; Jensen, Mie Micheelsen MD; Bojsen, Jonas Asgaard MD; Elhakim, Mohammad Talal MD; Florisson, Sandra MD; Saleh, Alisa; Clausen, Anne MSc; Moller, Soren PhD; Harbo, Frederik Severin Grae MD; Graumann, Ole PhD; Hallas, Jesper DrMedSci; Garcia Rodriguez, Luis Alberto MD; Al-Shahi Salman, Rustam MD, PhD; Goldstein, Larry B. MD; Gaist, David PhD
doi : 10.1212/WNL.0000000000201664
A causal relationship between statin use and intracerebral hemorrhage (ICH) is uncertain. We hypothesized that an association between long-term statin exposure and ICH risk might vary for different ICH locations
Association Between Serum Lipids and Survival in Patients With Amyotrophic Lateral Sclerosis: A Meta-analysis and Population-Based Study.
Janse van Mantgem, Mark R. MD; van Rheenen, Wouter MD, PhD; Hackeng, Anemone V. BSc; van Es, Michael A. MD, PhD; Veldink, Jan H. MD, PhD; van den Berg, Leonard H. MD, PhD *; van Eijk, Ruben P.A. MD, PhD *
Efficacy and Safety of N-Acetyl-L-Leucine in Children and Adults With GM2 Gangliosidoses.
Martakis, Kyriakos MD; Claassen, Jens MD; Gascon-Bayari, Jordi MD; Goldschagg, Nicolina MD; Hahn, Andreas MD; Hassan, Anhar MBBCh; Hennig, Anita MD; Jones, Simon MD; Kay, Richard PhD; Lau, Heather MD; Perlman, Susan MD; Sharma, Reena MD; Schneider, Susanne MD; Bremova-Ertl, Tatiana MD, PhD
doi : 10.1212/WNL.0000000000201660
GM2 gangliosidoses (Tay-Sachs and Sandhoff diseases) are rare, autosomal recessive, neurodegenerative diseases with no available symptomatic or disease-modifying treatments.
Multimorbidity and Sickness Absence/Disability Pension in Patients With Cluster Headache and Matched References: A Swedish Register-Based Study.
Ran, Caroline MSc, PhD; Alexanderson, Kristina PhD; Belin, Andrea C. MSc, PhD; Almondo, Gino MSc; Steinberg, Anna MD, PhD; Sjostrand, Christina MD, PhD
doi : 10.1212/WNL.0000000000201685
Multimorbidity among patients with cluster headache (CH) is considered to be high, but large studies are lacking. The aims were to explore the occurrence of diagnosis-specific multimorbidity among patients with CH and matched references and possible associations of this with their sickness absence and disability pension.
Impacts of Climate Change and Air Pollution on Neurologic Health, Disease, and Practice: A Scoping Review.
Louis, Shreya MD, MS; Carlson, Alise K. MD; Suresh, Abhilash BS; Rim, Joshua MD; Mays, MaryAnn MD; Ontaneda, Daniel MD, PhD; Dhawan, Andrew MD, DPhil
doi : 10.1212/WNL.0000000000201630
Although the international community collectively seeks to reduce global temperature rise to less than 1.5[degrees]C before 2100, irreversible environmental changes have already occurred, and as the planet warms, these changes will continue to occur.
Cathodal Transcranial Direct Current Stimulation for Treatment of Rasmussen Encephalitis.
Bangel, Katrin A.; Pang, Ki PhD, FRCPCH; Baker, Mark R. PhD, FRCP
Pearls & Oy-sters: Late-Onset Cobalamin C Deficiency Presenting With Subacute Combined Degeneration.
Goyne, Christopher MD; Kansal, Leena MD
doi : 10.1212/WNL.0000000000201695
AB Cobalamin C (CblC) deficiency is a rare inborn error in cobalamin (vitamin B12) metabolism which results in impaired intracellular processing of dietary vitamin B12. This leads to a wide range of clinical manifestations including cognitive impairment, psychiatric symptoms, myelopathy, thrombotic events, glomerulonephritis, and pulmonary arterial hypertension.
Teaching NeuroImage: Reinhold Hemimedullary Syndrome.
Kesav, Praveen MD, DM, PDF; Hussain, Syed Irteza MD; John, Seby MD; Sajjad, Zafar MD; Jacob, Anu MD, DM, FRCP
Teaching Video NeuroImage: Stop-Motion Chorea in PURA Syndrome.
Franklin, Gustavo Leite MD, PhD; Bacheladenski, Eli Paula MD; Rodrigues, Danielle C. B. MD; Crippa, Ana C.S. MD, PhD
Editors' Note: Infratentorial Brain Injury Among Patients Suspected of Death by Neurologic Criteria: A Systematic Review and Meta-analysis.
Lewis, Ariane MD; Galetta, Steven MD
Reader Response: Infratentorial Brain Injury Among Patients Suspected of Death by Neurologic Criteria: A Systematic Review and Meta-analysis.
Machado, Calixto
Author Response: Infratentorial Brain Injury Among Patients Suspected of Death by Neurologic Criteria: A Systematic Review and Meta-analysis.
Briard, Joel Neves; Chasse, Michael
Initial High-Efficacy Disease-Modifying Therapy in Multiple Sclerosis: A Nationwide Cohort Study.
Revise the Uniform Determination of Death Act to Align the Law With Practice Through Neurorespiratory Criteria.
