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Anti–Vascular Endothelial Growth Factor Therapy for Complications of Diabetic Retinopathy—From Treatment to Prevention?
Tien-En Tan, MBBS(Hons)1,2; Sobha Sivaprasad, DM3; Tien Yin Wong, MBBS, PhD1,2,4
doi : 10.1001/jamaophthalmol.2023.0496
March 2023, Vol 141, No. 3, Pages 222-293
An Outbreak of Fungal Endophthalmitis After Cataract Surgery in South Korea
Seong Woo Kim, MD, PhD1; Jae Hui Kim, MD2; Mihyun Choi, MD, PhD1; Sang Joon Lee, MD, PhD3; Jae Pil Shin, MD, PhD4; June Gone Kim, MD, PhD5; Se Woong Kang, MD, PhD6; Kyu Hyung Park, MD, PhD7; for the Korean Retina Society members
doi : 10.1001/jamaophthalmol.2022.5927
Importance Fungal endophthalmitis caused by contaminated medical products is extremely rare; it follows an intractable clinical course with a poor visual prognosis.
Neurologic Dysfunction Assessment in Parkinson Disease Based on Fundus Photographs Using Deep Learning
Sangil Ahn, BS1; Jitae Shin, PhD1; Su Jeong Song, MD, PhD2; Won Tae Yoon, MD, PhD3; Min Sagong, MD, PhD4; Areum Jeong, MD, PhD4; Joon Hyung Kim, MD5,6; Hyeong Gon Yu, MD, PhD6,7
doi : 10.1001/jamaophthalmol.2022.5928
Importance Until now, other than complex neurologic tests, there have been no readily accessible and reliable indicators of neurologic dysfunction among patients with Parkinson disease (PD).
Access to Pediatric Ophthalmological Care by Geographic Distribution and US Population Demographic Characteristics in 2022
Hannah L. Walsh, BS1; Abraham Parrish, MA, MILS2; Lauren Hucko, BA1; Jayanth Sridhar, MD3; Kara M. Cavuoto, MD3
doi : 10.1001/jamaophthalmol.2022.6010
Importance The geographic distribution of pediatric ophthalmological care has not been reported on since 2007; understanding this distribution could shed light on potential avenues to increase access, which is a necessary first step in addressing the pediatric ophthalmological needs of underserved areas.
Association of Blood Pressure With Rates of Macular Ganglion Cell Complex Thinning in Patients With Glaucoma
Vahid Mohammadzadeh, MD1; Erica Su, MS2; Massood Mohammadi, MD1; Simon K. Law, MD, PharmD1; Anne L. Coleman, MD, PhD1; Joseph Caprioli, MD1; Robert E. Weiss, PhD2; Kouros Nouri-Mahdavi, MD, MS1
doi : 10.1001/jamaophthalmol.2022.6092
Importance There are scarce data on the association of blood pressure measures with subsequent macular structural rates of change in patients with glaucoma.
Two-Year Outcomes After Variable Duration of Drug Cessation in Patients With Maculopathy Associated With Pentosan Polysulfate Use
Emily H. Jung, AB1; Aaron Lindeke-Myers, MD2; Nieraj Jain, MD3
doi : 10.1001/jamaophthalmol.2022.6093
Importance Prior retrospective studies have provided limited evidence on disease progression following drug cessation in patients with maculopathy associated with pentosan polysulfate (PPS).
Cost-effectiveness of Aflibercept Monotherapy vs Bevacizumab First Followed by Aflibercept If Needed for Diabetic Macular Edema
David W. Hutton, PhD1; Adam R. Glassman, MS2; Danni Liu, MSPH2; Jennifer K. Sun, MD, MPH3; for the DRCR Retina Network
doi : 10.1001/jamaophthalmol.2022.6142
Importance The DRCR Retina Network Protocol AC showed no significant difference in visual acuity outcomes over 2 years between treatment with aflibercept monotherapy and bevacizumab first with switching to aflibercept for suboptimal response in treating diabetic macular edema (DME).
Changes in Retinal Sensitivity Associated With Cotoretigene Toliparvovec in X-Linked Retinitis Pigmentosa With RPGR Gene Variations
Lenore von Krusenstiern, MD, PhD1,2; Jiajun Liu, PhD1,3; Eileen Liao, PhD1,4; James A. Gow, MD1; Guo Chen, PhD1,5; Tuyen Ong, MD1,6; Andrew J. Lotery, MD7,8; Assad Jalil, MBBS9; Byron L. Lam, MD10; Robert E. MacLaren, MB, ChB, DPhil11,12; for the XIRIUS Part 1 Study GroupXOLARIS Study Group
doi : 10.1001/jamaophthalmol.2022.6254
Importance X-linked retinitis pigmentosa (XLRP) is a severe cause of early-onset RP in male individuals, characterized by degeneration of photoreceptors, an extinguished electroretinogram, and vision loss.
Necrotizing Blepharoconjunctivitis and Keratitis in Human Monkeypox
Alfonso Vasquez-Perez, MD1; Tejal Magan, MD1; Giulio Volpe, MD, MPhil1; Sarah F. Osborne, MD1; Katie McFaul, MD, PhD2; Kaveh Vahdani, MD1
doi : 10.1001/jamaophthalmol.2022.6253
Importance Ophthalmic manifestations occur in less than 5% of patients with human mpox (monkeypox), most commonly presenting with self-limiting conjunctivitis and keratitis. Cases with severe ophthalmic complication are uncommon.
Deep Learning Using Images of the Retina for Assessment of Severity of Neurological Dysfunction in Parkinson Disease
Janan Arslan, MSc, MBiostat, PhD1; Daniel Racoceanu, PhD1; Kurt K. Benke, PhD2
Where Have All the Pediatric Ophthalmologists Gone?—Pediatric Eye Care Scarcity and the Challenge of Creating Equitable Health Care Access
Julius T. Oatts, MD1; Maanasa Indaram, MD1; Alejandra G. de Alba Campomanes, MD, MPH1
Blood Pressure and Glaucoma—A Complex Relationship
Angelo P. Tanna, MD1
Pentosan Polysulfate Maculopathy—We Need to Know More
Maureen G. Maguire, PhD1,2
Perspectives on Evolving Gene Therapy for X-Linked Retinitis Pigmentosa
Sabyasachi Sengupta, DNB1
Pigmented Corneal Lesions After Cataract Surgery
Sarah Schimansky, MB BCh BAO1; Omar El Haddad, MB BCh1,2
Bilateral Purtscher-Like Retinopathy Associated With COVID-19 Infection
Mitchell D. Thatcher, BSc1; Laura Z. Wu1; Renatta Varma, MD2
Necrotic Eruption of an Inflammatory Melanoma
Thamanna Nishath, MSPH1; K. Matthew McKay, MD1; Andrew W. Stacey, MD1
Annoying Conjunctival Thelaziasis in a Patient Aged 81 Years
Lusheng Ma, MD1; Jingyi Zhang, MD1; Lei Gao, MD2,3
