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Is Diabetes Mellitus a Blessing in Disguise for Primary Open-angle Glaucoma?
Hou, Huiyuan MD, PhD*; Moghimi, Sasan MD*; Baxter, Sally L. MD, MSc*,†; Weinreb, Robert N. MD
doi : 10.1097/IJG.0000000000001719
January 2021 - Volume 30 - Issue 1 - p 1-4
Although numbers of studies have addressed this question, the relationship between diabetes mellitus and primary open-angle glaucoma is still unclear. This article discusses progress in understanding the complex relationship between these 2 entities and recent shifts in perspective that challenge the traditional dogma regarding diabetes mellitus and primary open-angle glaucoma. There are still many unanswered questions.
Conversion of Flow-restrictive Ahmed Glaucoma Valve to a Nonrestrictive Drainage Implant by Slicing the Valve Leaflets: An In Vitro Study
Senthil, Sirisha FRCS*; Kumar, Gaddam Manoj BTech†; Sri Harsha Chittajallu, Sai Naga MTech†; Choudhari, Nikhil S. DNB*; Garudadri, Chandrasekar FRCS*; Richhariya, Ashutosh PhD†
doi : 10.1097/IJG.0000000000001671
January 2021 - Volume 30 - Issue 1 - p 5-9
With a newly designed blade, slicing of the Ahmed glaucoma valve (AGV) leaflets helped to convert the flow-restrictive AGV into a non–flow-restrictive device. Flow characteristics by our in-vitro study confirmed the loss of resistance of AGV valve leaflets.
Clinical Use of PanoMap for Glaucoma: Frequently Damaged Areas in Early Glaucoma
Lee, Won June MD, PhD*,†; Shin, Yong Un MD, PhD*,‡; Lim, Han Woong MD, PhD*,†; Cho, Heeyoon MD, PhD*,‡; Park, Ki Ho MD, PhD§,?; Seong, Mincheol MD, PhD*,‡
doi : 10.1097/IJG.0000000000001690
January 2021 - Volume 30 - Issue 1 - p 10-16
Recognizing the shortcomings of poor consistency of the fovea-disc relationship at different time points and comparing PanoMaps may well facilitate the understanding of the spatial relationship between parapapillary and macular areas in glaucoma.
Preliminary Report on a Novel Virtual Reality Perimeter Compared With Standard Automated Perimetry
Razeghinejad, Reza MD*; Gonzalez-Garcia, Alberto MD†; Myers, Jonathan S. MD*; Katz, L. Jay MD*
doi : 10.1097/IJG.0000000000001670
January 2021 - Volume 30 - Issue 1 - p 17-23
The VisuALL head-mounted perimetry in normal subjects and glaucoma patients had a moderate to strong correlation with the Humphrey Field Analyzer (HFA).
The Association of Intraocular Pressure With Obesity and Cardiometabolic Risk in a Young Farmworker Population
Reddy, Aditya BS*; Halenda, Kevin MD†; Cromer, Pamela DNP, FNP-BC‡; Chen, Li PhD*; Butler, Julian BS*; Raed, Anas MD*,§; Bhagatwala, Jigar MBBS, MPH*,§; Sponseller, Tracie OD†; Bollinger, Kathryn MD, PhD†; Zhu, Haidong MD, PhD*; Young, Lufei PhD‡; Layman, Debbie RN, BSN?; Dong, Yanbin MD, PhD*
doi : 10.1097/IJG.0000000000001673
January 2021 - Volume 30 - Issue 1 - p 24-31
Intraocular pressure (IOP) was found to be significantly correlated with body mass index (BMI), waist circumference, and diastolic blood pressure (DBP) in a farmworker population located in the southeast Georgia, USA. BMI was correlated with IOP, independent of systemic blood pressures.
Effect of Nylon Wick Technique on Early Intraocular Pressure Control in Nonvalved Aqueous Shunt Surgery
Swaminathan, Swarup S. MD*; Quist, Michael S. MD†; Dawson, Lindsay E. MD†; Rothman, Adam L. MD*; Herndon, Leon W. MD†
doi : 10.1097/IJG.0000000000001674
January 2021 - Volume 30 - Issue 1 - p 32-36
The use of nylon wicks with fenestrations in nonvalved aqueous shunt surgery significantly reduces intraocular pressure (IOP) and glaucoma medication usage in the immediate postoperative period compared with the use of fenestrations alone.
Effect of Sensitivity Disparity Between the Two Eyes on Pointwise Monocular Sensitivity Under Binocular Viewing in Patients With Glaucoma
Wakayama, Akemi PhD, CO*; Nomoto, Hiroki MD, PhD*; Chiba, Yasutaka PhD†; Matsumoto, Chota MD, PhD*; Kusaka, Shunji MD, PhD*
doi : 10.1097/IJG.0000000000001675
January 2021 - Volume 30 - Issue 1 - p 37-43
A difference between monocular sensitivities measured with and without occlusion was observed in glaucoma. Monocular sensitivity without occlusion could have been affected differently by binocular interaction due to the sensitivity disparity between both eyes.
Assessment of Corneal Epithelium Thickness in Glaucomatous Patients Undergoing Medical Treatment
Halkiadakis, Ioannis MD, PhD; Vernikou, Anna MD; Tzimis, Vasilis MD; Markopoulos, Ioannis MD, PhD; Popeskou, Korina MD; Konstadinidou, Vasiliki MD, PhD
doi : 10.1097/IJG.0000000000001677
January 2021 - Volume 30 - Issue 1 - p 44-49
Patients with glaucoma have reduced and irregular corneal epithelial thickness (CET) even if they do not report symptoms of dry eyes. The reduction of corneal epithelium affects equally the superior and inferior areas of the cornea.
Association of Nailfold Capillary Abnormalities With Primary Open-angle Glaucoma and Glaucomatous Visual Field Loss
Goh, Hilary MBChB*; Kersten, Hannah M. PhD†; Yoon, Jinny J. PhD*; Gossage, Lisa MA (Econ)‡; Danesh-Meyer, Helen V. MD, PhD*
doi : 10.1097/IJG.0000000000001678
January 2021 - Volume 30 - Issue 1 - p 50-57
Nailfold capillary abnormalities are associated with primary open-angle glaucoma (POAG) and increased severity of global and central glaucomatous visual field (VF) loss.
Remote Screening for Optic Nerve Cupping Using Smartphone-based Nonmydriatic Fundus Photography
LaMonica, Lauren C. MPH*; Bhardwaj, Mahesh K. OD†; Hawley, Nicola L. PhD*; Naseri, Take MBBS, MPH‡; Reupena, Muagatutia S. MS§; Cooper, Michael L. MD, PhD†; Cotran, Paul R. MD†; Roh, Shiyoung MD†,?; Ramsey, David J. MD, PhD, MPH†
doi : 10.1097/IJG.0000000000001680
January 2021 - Volume 30 - Issue 1 - p 58-60
Evaluation of nonmydriatic fundus photographs captured with a low-cost, smartphone-based camera facilitated remote screening of patients for enlarged optic nerve cup-to-disc ratio in the Independent Nation of Samoa, an underserved setting with one full-time ophthalmologist in the entire country.
Changes in Intraocular Pressure and Anterior Chamber Angle After Congenital Cataract Extraction
Gouda, Jylan MD; Tomairek, Reham H. MD; Elhusseiny, Abdelrahman M. MD; El-Fayoumi, Dina MD; Awadein, Ahmed MD; Gawdat, Ghada MD; Elhilali, Hala MD
doi : 10.1097/IJG.0000000000001681
January 2021 - Volume 30 - Issue 1 - p 61-64
Anterior chamber angle (ACA) narrowing continues to occur for at least 2 years after congenital cataract surgery. Risk factors for intraocular pressure (IOP) elevation after congenital cataract surgery were higher central corneal thickness (CCT) and surgery at <2 months.
Ophthalmic Artery and Superior Ophthalmic Vein Blood Flow Dynamics in Glaucoma Investigated by Phase Contrast Magnetic Resonance Imaging
Promelle, Veronique MD*,†,‡; Bouzerar, Roger PhD§; Daouk, Joel PhD§,?; Iscar, Claire MD*; Milazzo, Solange MD*,¶; Balédent, Olivier PhD
doi : 10.1097/IJG.0000000000001684
January 2021 - Volume 30 - Issue 1 - p 65-70
Ophthalmic artery (OA) and superior ophthalmic vein (SOV) blood flow were quantified by phase contrast magnetic resonance imaging (PC MRI) and seemed lower in glaucoma. Venous flow dynamics was different in glaucoma patients with a significantly decreased pulsatility.
Peripapillary and Macular Vessel Density Measurement With Optical Coherence Tomography Angiography in Exfoliation Syndrome
Gür Güng?r, Sirel MD; Sarigül Sezen?z, Almila MD, FEBO; ?ztürk, Caner MD; G?kg?z, Gül?ah MD; Akman, Ahmet MD
doi : 10.1097/IJG.0000000000001685
January 2021 - Volume 30 - Issue 1 - p 71-77
Although peripapillary retinal nerve fiber layer thickness (RNFLTs) and vessel density (VD) values were similar to healthy group, eyes with exfoliation syndrome had significantly lower superficial macular VDs and minimum ganglion cell analysis values.
Clinical Outcomes After Ahmed Glaucoma Valve Implantation for Pediatric Glaucoma After Congenital Cataract Surgery
Geyer, Orna MD; Segal, Adi MD; Melamud, Alina MD; Wolf, Alvit MDAuthor Information
doi : 10.1097/IJG.0000000000001689
January 2021 - Volume 30 - Issue 1 - p 78-82
Ahmed valve success for glaucoma following congenital cataract surgery lasts at least 5 years in most eyes, and >10 years in some cases. The procedure is a valuable option for these patients.
How Does Cataract Surgery Rate Affect Angle-closure Prevalence
Jin, Guangming MD, PhD*; Wang, Lanhua MD, PhD*; Scheetz, Jane PhD†; Zhang, Jian MSc*; He, Mingguang MD, PhD
doi : 10.1097/IJG.0000000000001691
January 2021 - Volume 30 - Issue 1 - p 83-88
A data simulation study suggests that prevalence of occludable angle will decrease when the cataract surgical rate increases in particularly when the surgery focuses on 70+ years old.
Trabecular Microbypass Stent and Phacoemulsification in African American Patients With Open-angle Glaucoma: Outcomes and Effect of Prior Laser Trabeculoplasty
Bargoud, Albert R. BA*; Lira, Jennifer MD†; An, Selena MD†; Walsman, Scott M. MD*; Herndon, Leon W. MD†; Khouri, Albert S. MD*
doi : 10.1097/IJG.0000000000001692
January 2021 - Volume 30 - Issue 1 - p 89-93
In African American patients with glaucoma, iStent/phacoemulsification lowered intraocular pressure and reduced glaucoma medication usage for up to 1 year, even in patients with prior selective laser trabeculoplasty (SLT).
Effect of Toric Intraocular Lens Implantation on Visual Acuity and Astigmatism Status in Eyes Treated With Microhook Ab Interno Trabeculotomy
Ichioka, Sho MD; Manabe, Kaoru MD; Tsutsui, Aika MD; Takai, Yasuyuki MD, PhD; Tanito, Masaki MD, PhD
doi : 10.1097/IJG.0000000000001705
January 2021 - Volume 30 - Issue 1 - p 94-100
Use of toric intraocular lenses is a reasonable option for better visual outcomes when a combined minimally invasive glaucoma surgery (MIGS) and cataract surgery is performed in eyes with corneal astigmatism.
Comparison of Gonioscopy-assisted Transluminal Trabeculotomy Versus Trabeculectomy With Mitomycin C in Patients With Open-angle Glaucoma
Fontana, Luigi MD, PhD*; De Maria, Michele MD*,†; Caristia, Alice MD*; Mastrofilippo, Valentina MS*; Braglia, Luca MS‡; Iannetta, Danilo MD*; Scarale, Giuliano Pio MD*
doi : 10.1097/IJG.0000000000001696
January 2021 - Volume 30 - Issue 1 - p 101-108
Trabeculectomy (TRAB) lowers the intraocular pressure (IOP) more than gonioscopy-assisted transluminal trabeculotomy (GATT) at 18 months, with a reduction in IOP of 30% or more and a significant reduction in the number of glaucoma medications compared with baseline.
Tube-Shunt Bleb Pathophysiology, the Cytokine Story
Freedman, Jeffrey MBBCh, PhD, FRCS(Edin), FCS(SA)
doi : 10.1097/IJG.0000000000001683
January 2021 - Volume 30 - Issue 1 - p 109-113
To define tube bleb-pathophysiology, outlining factors that may play a major role in the ultimate success or failure of the bleb. Methods that may be used to advance success of these blebs are discussed.
Juvenile Open-angle Glaucoma With Waardenburg Syndrome: A Case Report
AbdelRahman, Ahmed M. MD, FRCSEd; Amin, Rana H. MD, FRCS(gl)
doi : 10.1097/IJG.0000000000001676
January 2021 - Volume 30 - Issue 1 - p e1-e4
Waardenburg syndrome (WS) is a genetic disorder resulting in anomalies of derivatives of neural crest cells during development. Patients tend to have variable degrees of pigmentary defects affecting skin, hair, and irides in addition to hearing loss and possible systemic neurological associations. Elevation of the intraocular pressure has been reported in several adult patients with WS. We report the first case of WS to be associated with juvenile open-angle glaucoma in a 20-year-old Egyptian man thus expanding the spectrum of the types of glaucoma that can coexist with the syndrome.
Management Patterns and Visual Outcomes of Endophthalmitis After Glaucoma Drainage Device Placement: A Case Series
Robbins, Cason B. BS*; Feng, Henry L. MD†; Fekrat, Sharon MD, FACS†
doi : 10.1097/IJG.0000000000001679
January 2021 - Volume 30 - Issue 1 - p e5-e7
To describe clinical presentation, management, and outcomes of eyes with endophthalmitis related to glaucoma drainage device (GDD) placement.
Progression of Parapapillary Choroidal Microvascular Dropout After Disc Hemorrhage in Glaucoma Patients: 2 Case Reports
Lee, Jong Sub MD*,†; Lee, Won June MD, PhD*,†; Lim, Han Woong MD, PhD*,†; Seong, Mincheol MD, PhD*
doi : 10.1097/IJG.0000000000001688
January 2021 - Volume 30 - Issue 1 - p e8-e12
Microvasculature dropout (MvD) is a novel finding seen in optical coherence tomography angiography (OCTA), which is characterized by a localized dehiscence of the choriocapillaris in the parapapillary atrophy area. Disc hemorrhage (DH) is an important factor often associated with the development and especially progression of glaucoma. Here, we present 2 cases of MvD progression with DH.
Long-term Follow-up of 14 Eyes With Bilateral and Multiple Ciliary Body Cysts: Prognosis of this Rare Entity
Hugo, Juliette MD*,†; Feumi, Charles MD*,‡; Morin, Adèle MD*; Nguyen, Michelle MD*; Lachkar, Yves MD
doi : 10.1097/IJG.0000000000001693
January 2021 - Volume 30 - Issue 1 - p e13-e17
To describe the long-term outcomes of eyes with bilateral and multiple ciliary body cysts (CBC).
Can Breathing Exercise or Pranayama Affect the Intraocular Pressure in the Short-term?
Paidimarri, Suharsha MOpt*; Bhardwaj, Rishi PhD*; Pathak-Ray, Vanita FRCS (Ed), FRCOphth†
doi : 10.1097/IJG.0000000000001682
January 2021 - Volume 30 - Issue 1 - p e18-e20
To demonstrate any transient short-term effect of a particular type of breathing exercise (alternate nostril breathing of Nadi Shuddhi type of pranayama exercise) on the intraocular pressure (IOP) in glaucomatous as well as healthy eyes.
Glaucomatous Optic Neuropathy: Associated With Cognitive Impairment?
Norouzpour, Amir MD
doi : 10.1097/IJG.0000000000001668
January 2021 - Volume 30 - Issue 1 - p e21
Utility of the Modified Isolated-check Visual Evoked Potential Technique in Functional Glaucoma Assessment
Kolomeyer, Natasha N. MD*,†; Drinkwater, Owen J. BS, BA‡; Drivas, Eleni BA§; Zakik, Amir BS*; Zemon, Vance PhD?; Sidoti, Paul A. MD*,§; Tsai, James C. MD, MBA*,§; Panarelli, Joseph F. MD*
doi : 10.1097/IJG.0000000000001667
January 2021 - Volume 30 - Issue 1 - p e21-e22
Phacoemulsification Versus Phacotrabeculectomy in Primary Angle-closure Glaucoma With Cataract: Long-term Clinical Outcomes
Jain, Mugdha DNB; Dubey, Suneeta MS
doi : 10.1097/IJG.0000000000001687
January 2021 - Volume 30 - Issue 1 - p e22-e23
Responses to: Phacoemulsification Versus Phacotrabeculectomy in Primary Angle-closure Glaucoma With Cataract: Long-term Clinical Outcomes
Hansapinyo, Linda MD*,†,‡,§; Choy, Bonnie N.K. FRCS, FCOphthHK?; Lai, Jimmy S.M. MD, FRCS?; Tham, Clement C. FRCS, FCOphthHK*
doi : 10.1097/IJG.0000000000001686
January 2021 - Volume 30 - Issue 1 - p e23-e24
COVID-19 Pandemic: Are We Back to Normal?
Siesky, Brent PhD*; Harris, Alon MS, PhD, FARVO*; Verticchio Vercellin, Alice C. MD*,†,‡; Kalafatis, Nicholas BS§; Tsai, James C. MD, MBA
doi : 10.1097/IJG.0000000000001699
January 2021 - Volume 30 - Issue 1 - p e24-e25
