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Randomized Trials Fit for the 21st Century: A Joint Opinion From the European Society of Cardiology, American Heart Association, American College of Cardiology, and the World Heart Federation.
Bowman, Louise; Weidinger, Franz; Albert, Michelle A.; Fry, Edward T.A.; Pinto, Fausto J.; for the Clinical Trial Expert Group; and for the ESC Patient Forum; Achenbach, Stephan; Bowman, Louise; Casadei, Barbara; Collins, Rory; Devereaux, Philip J.; Douglas, Pamela S.; Frobert, Ole; Goto, Shinya; Grines, Cindy; Harrington, Robert A.; Haynes, Richard; Hochman, Judith S.; James, Stefan; Kirchhof, Paulus; Komajda, Michel; Lam, Carolyn S.P.; Landray, Martin; Maggioni, Aldo; McMurray, John; Medhurst, Nick; Neal, Bruce; Ryden, Lars; Thiele, Holger; Van Gelder, Isabelle; Wallentin, Lars; Yusuf, Salim; Zannad, Faiez
doi : 10.1161/CIRCULATIONAHA.122.063378
Volume 147(12) pgs. 925-989 March 21, 2023
Adults With Congenital Heart Disease: Trends in Event-Free Survival Past Middle Age.
Dellborg, Mikael MD, PhD; Giang, Kok Wai PhD; Eriksson, Peter MD, PhD; Liden, Hans MD, PhD; Fedchenko, Maria MD, PhD; Ahnfelt, Anders MD; Rosengren, Annika MD, PhD; Mandalenakis, Zacharias MD, PhD
doi : 10.1161/CIRCULATIONAHA.122.060834
The survival of children with congenital heart disease has increased substantially over the past decades, with 97% currently reaching adulthood. The total effect of advanced treatment on future mortality and morbidity in adult survivors with congenital heart disease (CHD) is less well described.
Adult Congenital Heart Disease: A Specialty With Ever-Expanding Challenges.
Rosenthal, Eric MD; Qureshi, Shakeel A. MBChB
Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program.
Small, Aeron M. MD, MTR *,,; Peloso, Gina M. PhD *,,; Linefsky, Jason MD; Aragam, Jayashri MD; Galloway, Ashley MPH; Tanukonda, Vidisha MD; Wang, Lu-Chen PhD; Yu, Zhi MB, PhD; Sunitha Selvaraj, Margaret PhD; Farber-Eger, Eric H. BS; Baker, Michael T. MD; Setia-Verma, Shefali MS; Lee, Simon S.K. MS; Preuss, Michael PhD; Ritchie, Marylyn D. PhD; Damrauer, Scott M. MD; Rader, Daniel J. MD; Wells, Quinn S. MD; Loos, Ruth PhD; Lubitz, Steven A. MD, MPH; Thanassoulis, George MD; Cho, Kelly PhD, MPH; Wilson, Peter W.F. MD; The VA Million Veteran Program; Natarajan, Pradeep MD, MMSc +,,,,; O'Donnell, Christopher J. MD, MPH +,,
doi : 10.1161/CIRCULATIONAHA.122.061451
Calcific aortic stenosis (CAS) is the most common valvular heart disease in older adults and has no effective preventive therapies. Genome-wide association studies (GWAS) can identify genes influencing disease and may help prioritize therapeutic targets for CAS.
Placental Inflammation Leads to Abnormal Embryonic Heart Development.
Ward, Eleanor J. PhD; Bert, Serena MSc; Fanti, Silvia MSc; Malone, Kerri M. PhD; Maughan, Robert T. PhD; Gkantsinikoudi, Christina MSc; Prin, Fabrice PhD; Volpato, Lia Karina MD, PhD; Piovezan, Anna Paula PhD; Graham, Gerard J. PhD; Dufton, Neil P. PhD; Perretti, Mauro PhD *,; Marelli-Berg, Federica M. MD, PhD *,; Nadkarni, Suchita PhD
doi : 10.1161/CIRCULATIONAHA.122.061934
Placental heart development and embryonic heart development occur in parallel, and these organs have been proposed to exert reciprocal regulation during gestation
Don't Break the Axis: Placental Inflammation Leads to Congenital Heart Disease.
de la Pompa, Jose Luis PhD
Risk of Heart Failure in Congenital Heart Disease: A Nationwide Register-Based Cohort Study.
Bergh, Niklas MD, PhD; Skoglund, Kristofer MD, PhD; Fedchenko, Maria MD, PhD; Bollano, Entela MD, PhD; Eriksson, Peter MD, PhD; Dellborg, Mikael MD, PhD; Wai Giang, Kok MD, PhD; Mandalenakis, Zacharias MD, PhD
Letter by Deng et al Regarding Article, "Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study".
Deng, Liling MD *,; Chen, Yan MD *,; Deng, Wuquan MD, PhD
Letter by Schmidt et al Regarding Article, "Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study".
Schmidt, Maria Ines MD, PhD; Bracco, Paula A.; Duncan, Bruce B.
Response by Tabak et al to Letters Regarding Article, "Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study".
Tabak, Adam G. MD, PhD; Sattar, Naveed MD, PhD; Kivimaki, Mika PhD
