American Journal of Gastroenterology




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Management of the Incidental Liver Lesion

Yataco, Maria L. MD1; Bowman, Andrew W. MD, PhD2; Keaveny, Andrew P. MD, FRCPI, FAASLD1

doi : 10.14309/ajg.0000000000001089

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 855-861

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Endoscopic Traction Techniques

Zheng, Shimeng MD1; Ali, Faisal S. MD2; Zhang, Jiyu MD1; Zhao, Lixia MD1; Liu, Bingrong MD, PhD1

doi : 10.14309/ajg.0000000000001100

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 862-866

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Intraductal Tubulopapillary Neoplasm of the Pancreas Presenting as Sausage

Lu, Zhong-fei MD1; Kang, Bing PhD2; Li, Jia-mei PhD3; Sun, Cong MD4

doi : 10.14309/ajg.0000000000000774

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 867

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Early Malignant Gastric Adenomyoma: A Rare Case

Yang, Xin MD1; Fan, Chaoqiang MD1; Sun, Ling MD1; Yang, Shiming MD1; Bai, Jianying MD1

doi : 10.14309/ajg.0000000000000815

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 868

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Gastrohepatic Fistula After Y-90 Embolization of Hepatocellular Carcinoma

Samoylova, Mariya L. MD, MAS1; Kapila, Nikhil MD2; McElroy, Lisa MD, MS1; Suhocki, Paul MD1; Segovia, M. Cristina MD1

doi : 10.14309/ajg.0000000000000793

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 869

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Chronic Mesenteric Ischemia With Peristaltic Blanching

Tsay, Cynthia J. MD, MPhil1; Protiva, Petr MD, MPH1,2

doi : 10.14309/ajg.0000000000000796

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 870

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Endoscopic Treatment for a Major Anastomotic Leakage After Colorectal Surgery: Transanal Fecal Diversion Approach

Liu, Yang MD1; Sun, Ling MD2; Zhang, Jianhong MD1; Li, Chuanfei MD3; Yang, Xin MD2

doi : 10.14309/ajg.0000000000000835

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 871

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Enhanced Suction During Esophagogastroduodenoscopy

Sobani, Zain A. MD1; Paleti, Swathi MD1; Malesich, Taylor CMA1; Rustagi, Tarun MD1

doi : 10.14309/ajg.0000000000001025

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 872

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CME Information

doi : 10.14309/ajg.0000000000001123

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 873-874

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Continuing Medical Education Questions: May 2021

Lui, Felix H. T. MD

doi : 10.14309/ajg.0000000000001284

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 875

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Continuing Medical Education Questions: May 2021

Davila, Raquel E. MD, FACG

doi : 10.14309/ajg.0000000000001277

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 876

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Continuing Medical Education Questions: May 2021

Cohen, Stanley M. MD, FACG

doi : 10.14309/ajg.0000000000001297

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 877

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ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

Chalasani, Naga P. MD, FACG1; Maddur, Haripriya MD2; Russo, Mark W. MD, MPH, FACG3; Wong, Robert J. MD, MS, FACG (GRADE Methodologist)4; Reddy, K. Rajender MD, FACG5, on behalf of the Practice Parameters Committee of the American College of Gastroenterology

doi : 10.14309/ajg.0000000000001259

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 878-898

Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology practices, and it can have multiple presentations, ranging from asymptomatic elevations in liver biochemistries to hepatocellular or cholestatic jaundice, liver failure, or chronic hepatitis. Antimicrobials, herbal and dietary supplements, and anticancer therapeutics (e.g., tyrosine kinase inhibitors or immune-checkpoint inhibitors) are the most common classes of agents to cause DILI in the Western world. DILI is a diagnosis of exclusion, and thus, careful assessment for other etiologies of liver disease should be undertaken before establishing a diagnosis of DILI. Model for end-stage liver disease score and comorbidity burden are important determinants of mortality in patients presenting with suspected DILI. DILI carries a mortality rate up to 10% when hepatocellular jaundice is present. Patients with DILI who develop progressive jaundice with or without coagulopathy should be referred to a tertiary care center for specialized care, including consideration for potential liver transplantation. The role of systemic corticosteroids is controversial, but they may be administered when a liver injury event cannot be distinguished between autoimmune hepatitis or DILI or when a DILI event presents with prominent autoimmune hepatitis features.

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ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding

Laine, Loren MD, FACG1,2; Barkun, Alan N. MD, FACG3; Saltzman, John R. MD, FACG4; Martel, Myriam MSc2; Leontiadis, Grigorios I. MD, PhD5

doi : 10.14309/ajg.0000000000001245

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 899-917

We performed systematic reviews addressing predefined clinical questions to develop recommendations with the GRADE approach regarding management of patients with overt upper gastrointestinal bleeding. We suggest risk assessment in the emergency department to identify very-low-risk patients (e.g., Glasgow-Blatchford score = 0–1) who may be discharged with outpatient follow-up. For patients hospitalized with upper gastrointestinal bleeding, we suggest red blood cell transfusion at a threshold of 7 g/dL. Erythromycin infusion is suggested before endoscopy, and endoscopy is suggested within 24 hours after presentation. Endoscopic therapy is recommended for ulcers with active spurting or oozing and for nonbleeding visible vessels. Endoscopic therapy with bipolar electrocoagulation, heater probe, and absolute ethanol injection is recommended, and low- to very-low-quality evidence also supports clips, argon plasma coagulation, and soft monopolar electrocoagulation; hemostatic powder spray TC-325 is suggested for actively bleeding ulcers and over-the-scope clips for recurrent ulcer bleeding after previous successful hemostasis. After endoscopic hemostasis, high-dose proton pump inhibitor therapy is recommended continuously or intermittently for 3 days, followed by twice-daily oral proton pump inhibitor for the first 2 weeks of therapy after endoscopy. Repeat endoscopy is suggested for recurrent bleeding, and if endoscopic therapy fails, transcatheter embolization is suggested.

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Obesity Primer for the Practicing Gastroenterologist

Jirapinyo, Pichamol MD, MPH1,2; Thompson, Christopher C. MD, MSc1,2

doi : 10.14309/ajg.0000000000001200

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 918-934

With worsening of the obesity pandemic, gastroenterologists will see more patients with this chronic disease. Given the association between obesity and several gastrointestinal conditions and the interplay between obesity pathophysiology and gut hormones, gastroenterologists can play an important role in the management of this disease. Furthermore, because more patients undergo bariatric surgery, an understanding of postsurgical anatomy and medical and endoscopic management of bariatric surgical complications is essential. This article provides clinical tools for the assessment and management of obesity for the general gastroenterologist. Tables containing high-yield practical information are also provided for quick reference.

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Small Intestinal Bacterial Overgrowth in Functional Dyspepsia: A Systematic Review and Meta-Analysis

Gurusamy, Saravana Ruban MBBS1,2; Shah, Ayesha MBBS, PhD, FRACP1,2,*; Talley, Nicholas J. MD, PhD, FRACP, FAHMS3,*; Koloski, Natasha PhD1,2,3,*; Jones, Michael P. BSc (Hons), PhD, ASTAT, CSTAT4,*; Walker, Marjorie M. BMedSci, BMBS, FRCPath, FRCPA, AGAF3,*; Morrison, Mark PhD1,5,*; Holtmann, Gerald MD, PhD, MBA, FRACP, FAHMS1,2,*

doi : 10.14309/ajg.0000000000001197

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 935-942

This systematic review and meta-analysis aimed to determine the role of small intestinal bacterial overgrowth (SIBO) in patients with functional dyspepsia (FD).

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Persisting Villous Atrophy and Adherence in Celiac Disease: What Does the Patient Want? What Should a Clinician Advise?

Rej, Anupam MBChB, BMedSci, MRCP1; Elli, Luca MD, PhD2; Sanders, David Surendran MBChB, MRCP, MD, FACG, FRCP1,3

doi : 10.14309/ajg.0000000000001244

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 946-948

Adherence to a gluten-free diet in celiac disease remains challenging. Clinicians may view mucosal healing as crucial. From the patient's perspective, avoidance of an invasive upper endoscopy may be desirable. A fundamental misconception is that noninvasive tools including symptoms, serology, dietary adherence questionnaires, and novel gluten immunogenic peptides may detect ongoing villous atrophy rather than assess adherence. Duodenal biopsies are the only reliable method for assessment of mucosal healing—however, we as clinicians should provide patients with the uncertainties of this approach allowing them to make an informed decision on an individual basis.

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A Riddle, Wrapped in a Mystery, Inside an Enigma: Another Key to Wheat Sensitivity?

Galipeau, Heather J. PhD1; Verdu, Elena F. MD, PhD1

doi : 10.14309/ajg.0000000000001241

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 943-945

Nonceliac gluten sensitivity, or the more preferred term, nonceliac wheat sensitivity (NCWS), is a heterogenous condition that is diagnosed purely on the basis of symptoms and without an understanding of disease mechanisms and triggers. Biomarkers to identify patients and implementation of dietary treatment in a personalized manner are needed. Mansueto et al. identified a population of NCWS patients with associated autoimmune markers and immune activation. The presence of these markers could be used, in combination with other serological tests, to help develop better diagnostic strategies for NCWS.

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Validation of Tools for Predicting Incident Adenocarcinoma of the Esophagus or Esophagogastric Junction

Rubenstein, Joel H. MD, MSc1,2; Raghunathan, Trivellore PhD3,4; Doan, Cecilia MPH5; Schneider, Jennifer MPH5; Zhao, Wei MPH5; Metko, Valbona MD2; Nofz, Kimberly BSN, RN1; Khodadost, Maryam MS1; Corley, Douglas A. MD, PhD5

doi : 10.14309/ajg.0000000000001255

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 949-957

Guidelines suggest screening of individuals who are at increased risk of esophageal adenocarcinoma (EAC). Tools for identifying patients at risk of Barrett's esophagus have been validated. Here, we aimed to compare and validate the tools for the primary outcomes of interest: EAC and esophagogastric junction adenocarcinoma (EGJAC).

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Previously Attempted Large Nonpedunculated Colorectal Polyps Are Effectively Managed by Endoscopic Mucosal Resection

Shahidi, Neal MD1,2,3; Vosko, Sergei MD1; Gupta, Sunil MBBS1,2; van Hattem, W. Arnout MD, PhD1; Sidhu, Mayenaaz MD1,2; Tate, David J. MBBS, PhD4; Williams, Stephen J. MBBS1,2; Lee, Eric Y.T. MBBS1,2; Burgess, Nicholas MBChB, PhD1,2; Bourke, Michael J. MBBS1,2

doi : 10.14309/ajg.0000000000001096

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 958-966

Endoscopic mucosal resection (EMR) is an effective therapy for naive large nonpedunculated colorectal polyps (N-LNPCPs). The best approach for the treatment of previously attempted LNPCPs (PA-LNPCPs) is undetermined.

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Strong Reduction of Colorectal Cancer Incidence and Mortality After Screening Colonoscopy: Prospective Cohort Study From Germany

Guo, Feng MSc1,2; Chen, Chen PhD1; Holleczek, Bernd PhD3; Sch?ttker, Ben PhD1,4; Hoffmeister, Michael PhD1; Brenner, Hermann MD, MPH1,5,6

doi : 10.14309/ajg.0000000000001146

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 967-975

A claimed advantage of colonoscopy over sigmoidoscopy in colorectal cancer (CRC) screening is prevention of CRC not only in the distal colon and rectum but also in the proximal colon. We aimed to assess the association of screening colonoscopy use with overall and site-specific CRC incidence and associated mortality.

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Randomized Clinical Trial of Inreach With or Without Mailed Outreach to Promote Hepatitis C Screening in a Difficult-to-Reach Patient Population

Desai, Nirali MD1; Rich, Nicole E. MD1,2; Jain, Mamta K. MD, MPH1,2; Blackwell, James-Michael MPH3; Murphy, Caitlin C. PhD3; Perryman, Patrice MPH3; McBryde, Jennifer PA-C2; Quirk, Lisa MS3; Clark, Christopher BS2; Villarreal, Deyaun PhD3; Waljee, Akbar K. MD MS4,5; Gopal, Purva MD6; Singal, Amit G. MD, MS1,2,3,7

doi : 10.14309/ajg.0000000000001085

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 976-983

Hepatitis C virus (HCV) treatment can significantly reduce the risk of liver-related mortality; however, many patients remain unaware of their infection in clinical practice. The aim of this study is to compare the effectiveness of inreach, with and without mailed outreach, to increase HCV screening and follow-up in a large, difficult-to-reach patient population.

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A Sequential Algorithm Combining ADAPT and Liver Stiffness Can Stage Metabolic-Associated Fatty Liver Disease in Hospital-Based and Primary Care Patients

Eslam, Mohammed MD, PhD1; Wong, Grace Lai-Hung MD2,3; Hashem, Ahmed M. PhD4; Chan, Henry Lik-Yuen MD2,3; Nielsen, Mette Juul PhD5; Leeming, Diana Julie PhD5; Chan, Anthony Wing-Hung MD6; Chen, Yu PhD7; Duffin, Kevin L. PhD7; Karsdal, Morten PhD5; Schattenberg, J?rn M. MD8; George, Jacob MD, PhD1; Wong, Vincent Wai-Sun MD2,3

doi : 10.14309/ajg.0000000000001059

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 984-993

Metabolic-associated fatty liver disease is common, with fibrosis the major determinant of adverse outcomes. Population-based screening tools with high diagnostic accuracy for the staging of fibrosis are lacking.

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Impact of the Association Between PNPLA3 Genetic Variation and Dietary Intake on the Risk of Significant Fibrosis in Patients With NAFLD

Vilar-Gomez, Eduardo MD1; Pirola, Carlos Jose PhD2; Sookoian, Silvia MD3; Wilson, Laura A. ScM4; Belt, Patricia PhD4; Liang, Tiebing PhD1; Liu, Wanqing PhD5,6,7; Chalasani, Naga MD1

doi : 10.14309/ajg.0000000000001072

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 994-1006

This study explored the relationship between patatin-like phospholipase domain-containing 3 gene (PNPLA3 rs738409), nutrient intake, and liver histology severity in patients with nonalcoholic fatty liver disease (NAFLD).

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Higher Postinduction Infliximab Concentrations Are Associated With Improved Clinical Outcomes in Fistulizing Crohn's Disease: An ACCENT-II Post Hoc Analysis

Papamichael, Konstantinos MD, PhD1; Vande Casteele, Niels PharmaD, PhD2,3; Jeyarajah, Jenny PhD3; Jairath, Vipul MD, PhD3,4; Osterman, Mark T. MD, MS5; Cheifetz, Adam S. MD1

doi : 10.14309/ajg.0000000000001111

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1007-1014

There are only limited data regarding the role of therapeutic drug monitoring in fistulizing Crohn's disease (CD). We investigated the association between both induction and maintenance serum infliximab concentrations and favorable therapeutic outcomes in patients with fistulizing CD.

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Autoimmunity Features in Patients With Non-Celiac Wheat Sensitivity

Mansueto, Pasquale MD1; Soresi, Maurizio MD1; Candore, Giuseppina PhD2,3; Garlisi, Chiara MD1; Fayer, Francesca PhD1; Gambino, Caterina Maria PhD2; La Blasca, Francesco MD1; Seidita, Aurelio MD1; D'Alcamo, Alberto MD1; Lo Sasso, Bruna PhD2,3; Florena, Ada Maria MD4; Geraci, Girolamo MD5; Caio, Giacomo MD6; Volta, Umberto MD7; De Giorgio, Roberto MD6; Ciaccio, Marcello MD, PhD2,3; Carroccio, Antonio MD8

doi : 10.14309/ajg.0000000000000919

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1015-1023

Nonceliac wheat sensitivity (NCWS) is characterized by intestinal and extraintestinal manifestations consequent to wheat ingestion in subjects without celiac disease and wheat allergy. Few studies investigated the relationship between NCWS and autoimmunity. The aim of this study is to evaluate the frequency of autoimmune diseases (ADs) and autoantibodies in patients with NCWS.

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Electroacupuncture vs Prucalopride for Severe Chronic Constipation: A Multicenter, Randomized, Controlled, Noninferiority Trial

Liu, Baoyan MD1; Wu, Jiani MD, PhD1; Yan, Shiyan PhD2; Zhou, Kehua MD, DPT3; He, Liyun MD, PhD2; Fang, Jianqiao MD, PhD4; Fu, Wenbin MD5; Li, Ning MD6; Su, Tongsheng MD7; Sun, Jianhua MD, PhD8; Zhang, Wei MD, PhD9; Yue, Zenghui MD10; Zhang, Hongxing MD, PhD11; Zhao, Jiping MD12; Zhou, Zhongyu MD13; Song, Hujie MD14; Wang, Jian MD, PhD15; Liu, Li'an MD, PhD16; Wang, Linpeng MD17; Lv, Xiaoying MD2; Yang, Xiaofang MD, PhD18; Liu, Yan MD19; Sun, Yuanjie MD1; Wang, Yang MD, PhD1; Qin, Zongshi MD1; Zhou, Jing MD, PhD1; Liu, Zhishun MD, PhD1

doi : 10.14309/ajg.0000000000001050

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1024-1035

This multicenter, randomized, noninferiority trial compared electroacupuncture with prucalopride for the treatment of severe chronic constipation (SCC).

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Persistent Villous Atrophy in De Novo Adult Patients With Celiac Disease and Strict Control of Gluten-Free Diet Adherence: A Multicenter Prospective Study (CADER Study)

Fern?ndez-Ba?ares, Fernando MD, PhD1,2; Beltr?n, Belén MD, PhD2,3; Salas, Antonio MD, PhD4; Comino, Isabel PhD5; Ballester-Clau, Raquel MD, PhD6; Ferrer, Carme MD4; Molina-Infante, Javier MD, PhD2,7; Rosinach, Mercé MD1; Modolell, Inés MD, PhD8; Rodr?guez-Moranta, Francisco MD, PhD9; Arau, Beatriz MD1,2; Segura, Ver?nica BSc5; Fern?ndez-Salazar, Luis MD, PhD10; Santolaria, Santos MD, PhD11; Esteve, Maria MD, PhD1,2; Sousa, Carolina PhD5, on behalf of the CADER study group

doi : 10.14309/ajg.0000000000001139

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1036-1043

no abstract

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Efficacy and Safety of Sirolimus for Blue Rubber Bleb Nevus Syndrome: A Prospective Study

Zhou, Jiaolin MD1; Zhao, Zichen MDc2; Sun, Tao MD, PhD3; Liu, Wei MD4; Yu, Zhongxun MD5; Liu, Jingjuan MD4; Yu, Yiqi MDc2; Ning, Shoubin MD, PhD3; Zhang, Hongbing MD, PhD6,7

doi : 10.14309/ajg.0000000000001117

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1044-1052

Blue rubber bleb nevus syndrome (BRBNS) is a rare systemic venous malformation (VM) disease. The characteristic gastrointestinal (GI) bleeding from multiple VM lesions causes severe chronic anemia which renders most patients depend on lifelong blood transfusion and frequent endoscopic treatment with dismayed outcomes. Although recent case reports suggest that oral sirolimus (rapamycin) is effective, a comprehensive evaluation of its efficacy and safety is in need.

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Trends in the Mortality of Biliary Tract Cancers Based on Their Anatomical Site in the United States From 2009 to 2018

Kim, Donghee MD, PhD1; Konyn, Peter MD2; Cholankeril, George MD1; Bonham, Clark Andrew MD3; Ahmed, Aijaz MD1

doi : 10.14309/ajg.0000000000001151

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1053-1062

Recent trends in the incidence and mortality of biliary tract cancers are unknown. We estimated the trends in biliary tract cancers–related incidence and mortality stratified by anatomical site, age, sex, and race/ethnicity in the US adults.

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Subsequent Primary Cancers of the Digestive System Among Childhood and Adolescent Cancer Survivors From 1975 to 2015 in the United States

Liu, Jason J. ScD1; Chen, Chuan-Yu PhD1; Giovannucci, Edward MD2; Wu, Chun-Ying MD, PhD3

doi : 10.14309/ajg.0000000000001133

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1063-1071

Among survivors from first primary cancers that occurred during childhood and adolescence, their risks of developing subsequent primary digestive system cancers are not well understood. Therefore, we conducted the largest and most comprehensive analysis examining risks for diverse types of digestive system cancers after survival from a wide variety of first primary childhood and adolescent cancers.

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International Trends in Esophageal Squamous Cell Carcinoma and Adenocarcinoma Incidence

Rumgay, Harriet BSc1; Arnold, Melina PhD1; Laversanne, Mathieu MSc1; Whiteman, David C. MBBS, PhD2; Thrift, Aaron P. PhD3,4; Wei, Wenqiang PhD5; Lemmens, Valery E. P. P. PhD6,7; Soerjomataram, Isabelle PhD1

doi : 10.14309/ajg.0000000000001121

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1072-1076

We aimed to improve our understanding of the epidemiology of squamous cell carcinoma and adenocarcinoma of the esophagus.

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Heavy Alcohol Use Is Associated With Gastric Cancer: Analysis of the National Health and Nutrition Examination Survey From 1999 to 2010

Laszkowska, Monika MD, MS1,2; Rodriguez, Steven MD3; Kim, Judith MD1; Hur, Chin MD MPH1,3,4

doi : 10.14309/ajg.0000000000001166

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1083-1086

Evidence regarding the association between alcohol use and gastric cancer (GC) has been inconsistent.

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Post–COVID-19 Cholangiopathy: A Novel Entity

Roth, Nitzan C. MD, PhD1; Kim, Angela MD2; Vitkovski, Taisia DO3; Xia, Jianxiang MD4; Ramirez, Guillermo MD2; Bernstein, David MD1; Crawford, James M. MD, PhD3

doi : 10.14309/ajg.0000000000001154

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1077-1082

Liver chemistry abnormalities are a frequent manifestation of coronavirus disease 2019 (COVID-19) but are usually transient and resolve with disease resolution.

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Online Video Clinic Satisfies the Medical Requirements of Patients with IBD During the COVID-19 Outbreak

Tang, Jian MM1; Huang, Zicheng MM1; Guo, Huili MM1; Ding, Ni MM1; Gao, Xiang PhD1

doi : 10.14309/ajg.0000000000001033

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1087

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Response to Tang, et al.

Shah, Eric D. MD, MBA, FACG1; Amann, Stephen T. MD, FACG2; Karlitz, Jordan J. MD, FACG3

doi : 10.14309/ajg.0000000000001070

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1087-1088

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Telemedicine in the Time of COVID-19: Better Late Than Never

Koulaouzidis, George MD, PhD1; Marlicz, Wojciech MD, PhD2; Koulaouzidis, Anastasios MD, DM, PhD3

doi : 10.14309/ajg.0000000000001035

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1088-1089

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Response to Koulaouzidis, et al.

Shah, Eric D. MD, MBA, FACG1; Amann, Stephen T. MD, FACG2; Karlitz, Jordan J. MD, FACG3

doi : 10.14309/ajg.0000000000001071

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1089

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Nonvitamin K Antagonist Oral Anticoagulants Reduced the Risk of Liver Injury in Atrial Fibrillation Patients

Liu, Rongqiang MD1; Ye, Linsen PhD2; Shao, Yi PhD3

doi : 10.14309/ajg.0000000000000930

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1090

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Database Studies on Drug-Induced Liver Injury: The Importance of Causality Assessment

Bj?rnsson, Helgi K. MD1,2; Bj?rnsson, Einar S. MD, PhD1,2

doi : 10.14309/ajg.0000000000001015

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1090-1091

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Response to Liu et al., and Bj?rnsson and Bj?rnsson

Zhao, Jiaxi MSc1,2; Blais, Joseph E. BScPharm1; Seto, Wai-Kay MD3,4,5; Wong, Ian C.K. PhD1,6; Chan, Esther W. PhD1,2

doi : 10.14309/ajg.0000000000001055

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1091-1092

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Smoking Is Consistently Associated With Major Molecular Subtypes of Colorectal Cancer

Hoffmeister, Michael PhD, MSc1; Brenner, Hermann MD, MPH1,2,3; Amitay, Efrat L. PhD, MPH1

doi : 10.14309/ajg.0000000000001051

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1092-1093

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Response to Hoffmeister et al.

Botteri, Edoardo PhD1,2; Gallus, Silvano ScD3; Lugo, Alessandra PhD3

doi : 10.14309/ajg.0000000000001152

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1093-1094

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Response to Anand and Sharma

Benmassaoud, Amine MD1; Tsochatzis, Emmanuel MD2,3

doi : 10.14309/ajg.0000000000001108

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1094-1095

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Sarcopenia Does Not Worsen Outcomes in Patients With Refractory Ascites Under Transjugular Intrahepatic Portosystemic Shunt Placement—Preliminary Evidence?

Anand, Abhinav MD1; Sharma, Sanchit MD1

doi : 10.14309/ajg.0000000000001053

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1095-1096

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Possible Endoscopic Exposure to COVID Despite Negative Pre-Endoscopic Testing

Nordstrom, Carl MD1

doi : 10.14309/ajg.0000000000001060

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1096

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Noninvasive Diagnosis of Clinically Significant Portal Hypertension in Patients With Compensated Liver Disease: Whom and How to Screen?

Sharma, Sanchit MD1; Agarwal, Samagra MD1; Anand, Abhinav MD1

doi : 10.14309/ajg.0000000000001078

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1096-1097

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A Tip of the Iceberg on the Mechanism of SARS-CoV-2–Induced Liver Injury

Wang, Runsheng MS1; Yang, Lijing MD, PhD2; Hu, Chao MS1; Yan, Junhong MD3; Hu, Peng MS1; Li, Hongxia MD1; Xu, Guogang MD, PhD4; Pan, Lei MD, PhD5; Tu, Lei MD, PhD6

doi : 10.14309/ajg.0000000000001103

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1097-1098

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Lopinavir-Ritonavir and Liver Involvement in Patients With COVID-19

Lv, Xiu-He MD1,2; Yang, Jin-Lin MD1,2; Deng, Kai MD1,2,3,4

doi : 10.14309/ajg.0000000000001043

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1099

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Correction to: Characteristics Associated With Clinically Important Treatment Responses in Women Undergoing Non-Surgical Therapy for Fecal Incontinence

Richter, Holly E. PhD, MD1; Jelovsek, J.E. MD, MMeD2; Iyer, P. BSPH3; Rogers, R.G. MD4,5; Meyer, I. MD, MSPH1; Newman, D.K. DNP, FAAN, BCB-PMD6; Bradley, M.S. MD7; Harm-Ernandes, I. PT8; Dyer, K.Y. MD9; Wohlrab, K. MD10; Mazloomdoost, D. MD11; Gantz, M.G. PhD3

doi : 10.14309/ajg.0000000000001232

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1100

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Calendar of Courses, Symposiums and Conferences

doi : 10.14309/ajg.0000000000001279

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1101

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Reviewer Recognition

doi : 10.14309/ajg.0000000000001258

The American Journal of Gastroenterology: May 2021 - Volume 116 - Issue 5 - p 1102-1105

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