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Bimekizumab effective across the axSpA spectrum
Sarah OnuoraÂÂ
doi : 10.1038/s41584-023-00927-3
Volume 19 Issue 3, March 2023
Are the origins of adult arthritis seeded during embryonic development?
Annie Hackland & Adam P. CroftÂ
ERAP1 and the return of the UPR in ankylosing spondylitis
Nigil Haroon & Robert D. InmanÂ
Intervertebral disc degeneration and osteoarthritis: a common molecular disease spectrum
Noah Fine, Starlee Lively, Cheryle Ann Séguin, Anthony V. Perruccio, Mohit Kapoor & Raja RampersaudÂ
doi : 10.1038/s41584-022-00888-z
Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the spine are biomechanically interdependent, typically occur in tandem, and have considerable epidemiological and pathophysiological overlap.
Phenotypic heterogeneity in psoriatic arthritis: towards tissue pathology-based therapy
Aurelie Najm, Carl S. Goodyear, Iain B. McInnes & Stefan SiebertÂ
doi : 10.1038/s41584-022-00874-5
Psoriatic arthritis (PsA) is a heterogeneous disease involving multiple potential tissue domains. Most outcome measures used so far in randomized clinical trials do not sufficiently reflect this domain heterogeneity.
Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management
Zsuzsanna H. McMahan, Subhash Kulkarni, Joan Chen, Jiande Z. Chen, Ramnik J. Xavier, P. Jay Pasricha & Dinesh KhannaÂ
doi : 10.1038/s41584-022-00900-6
Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the gastrointestinal tract, and the severity of gastrointestinal disease in SSc correlates with high mortality.
A path towards personalized medicine for autoinflammatory and related diseases
Jonathan J. Miner & Katherine A. FitzgeraldÂ
doi : 10.1038/s41584-022-00904-2
The human genome project led to the advancement of genetic technologies and genomic medicine for a variety of human diseases, including monogenic autoimmune and autoinflammatory diseases.
Author Correction: Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management
Zsuzsanna H. McMahan, Subhash Kulkarni, Joan Chen, Jiande Z. Chen, Ramnik J. Xavier, P. Jay Pasricha & Dinesh KhannaÂ
