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Trajectories of self-reported hearing and their associations with cognition: evidence from the United Kingdom and United States of America
Katey Matthews, Piers Dawes, Rebecca Elliot, Neil Pendleton, Gindo Tampubolon, Asri Maharani
doi : 10.1093/ageing/afad017
Age and Ageing, Volume 52, Issue 2, February 2023, afad017
This study aimed to investigate the relationships between trajectories of change in self-reported hearing over eight years with subsequent effects on cognition, measured using episodic memory.
Long-term fine particular exposure and incidence of frailty in older adults: findings from the Chinese Longitudinal Healthy Longevity Survey
Yuebin Lv, Ze Yang, Lihong Ye, Meijie Jiang, Jinhui Zhou, Yanbo Guo, Yidan Qiu, Xinwei Li, Chen Chen, Aipeng Ju, Jun Wang, Chenfeng Li, Yang Li, Jiaonan Wang, Juan Zhang, John S Ji, Tiantian Li, Andrea A Baccarelli, Xu Gao, Xiaoming Shi
doi : 10.1093/ageing/afad009
Age and Ageing, Volume 52, Issue 2, February 2023, afad009
The association between fine particular matter (PM2.5) and frailty is less studied, and the national burden of PM2.5-related frailty in China is unknown.
Higher dietary protein intake is associated with sarcopenia in older British twins
Mary Ni Lochlainn, Ruth C E Bowyer, Ailsa A Welch, Kevin Whelan, Claire J Steves
doi : 10.1093/ageing/afad018
Age and Ageing, Volume 52, Issue 2, February 2023, afad018
Sarcopenia, characterised by an accelerated loss of skeletal muscle mass and function, is associated with negative outcomes. This study aimed to evaluate factors associated with skeletal muscle strength, mass and sarcopenia, particularly protein intake, and to assess whether shared twin characteristics are important.
Adverse Childhood Experiences and frailty in later life: a prospective population-based cohort study
Menelaos M Dimitriadis, Hans W Jeuring, Radboud M Marijnissen, Thomas H Wieringa, Emiel O Hoogendijk, Richard C Oude Voshaar
doi : 10.1093/ageing/afad010
Age and Ageing, Volume 52, Issue 2, February 2023, afad010,
The deficit accumulation method considers the ageing process underlying frailty as a random accumulation of health deficits.
The impact of study factors in the association of periodontal disease and cognitive disorders: systematic review and meta-analysis
Harriet Larvin, Chenyi Gao, Jing Kang, Vishal R Aggarwal, Susan Pavitt, Jianhua Wu
doi : 10.1093/ageing/afad015
Age and Ageing, Volume 52, Issue 2, February 2023, afad015
The aim was to assess study factors that impact the association of cognitive disorders in people with periodontal disease (PD).
New horizons in understanding oral health and swallowing function within the context of frailty
Raele Robison, Kendrea L (Focht) Garand, Rebecca Affoo, Chih-Ko Yeh, Nathaniel Chin, Caitlin McArthur, Michael Pulia, Nicole Rogus-Pulia
doi : 10.1093/ageing/afac276
Age and Ageing, Volume 52, Issue 2, February 2023, afac276
Frailty is a complex and multidimensional condition wherein declines in physiologic reserve and function place individuals in a state of heightened vulnerability and decreased resiliency.
New horizons in managing older cancer survivors: complexities and opportunities
Anna R A Mislang, Arduino A Mangoni, Angela Molga, Swatee Jena, Bogda Koczwara
doi : 10.1093/ageing/afad008
Age and Ageing, Volume 52, Issue 2, February 2023, afad008
Older adults represent a growing population amongst cancer survivors who require specific consideration given the complex and largely unknown interactions between cancer-related concerns and age-related conditions.
Inflammaging as a target for healthy ageing
Ben Dugan, Jessica Conway, Niharika A Duggal
doi : 10.1093/ageing/afac328
Age and Ageing, Volume 52, Issue 2, February 2023, afac328
Life expectancy has been on the rise for the past few decades, but healthy life expectancy has not kept pace, leading to a global burden of age-associated disorders.
Comparative effectiveness of non-pharmacological interventions for frailty: a systematic review and network meta-analysis
Xuemei Sun, Wenqi Liu, Yinyan Gao, Lang Qin, Hui Feng, Hongzhuan Tan, Qiong Chen, Linlin Peng, Irene X Y Wu
doi : 10.1093/ageing/afad004
Age and Ageing, Volume 52, Issue 2, February 2023, afad004
Frailty endangers the health of older adults. Furthermore, the prevalence of frailty continues to increase as the global population ageing.
Late-life depression and multimorbidity trajectories: the role of symptom complexity and severity
Federico Triolo, Linnea Sjöberg, Amaia Calderón-Larrañaga, Martino Belvederi Murri, Davide Liborio Vetrano, Laura Fratiglioni, Serhiy Dekhtyar
doi : 10.1093/ageing/afac315
Age and Ageing, Volume 52, Issue 2, February 2023, afac315
as late-life depression is associated with poor somatic health, we aimed to investigate the role of depression severity and symptom phenotypes in the progression of somatic multimorbidity.
External validation of the hospital frailty risk score among hospitalised home care clients in Canada: a retrospective cohort study
Luke Andrew Turcotte, George Heckman, Kenneth Rockwood, Davide Liborio Vetrano, Paul Hébert, Daniel I McIsaac, Elizabeth Rhynold, Lori Mitchell, Fabrice Immanuel Mowbray, Rasmus T Larsen, John P Hirdes
doi : 10.1093/ageing/afac334
Age and Ageing, Volume 52, Issue 2, February 2023, afac334
The Hospital Frailty Risk Score (HFRS) is scored using ICD-10 diagnostic codes in administrative hospital records. Home care clients in Canada are routinely assessed with Resident Assessment Instrument-Home Care (RAI-HC) which can calculate the Clinical Frailty Scale (CFS) and the Frailty Index (FI).
The ‘Bermuda Triangle’ of orthostatic hypotension, cognitive impairment and reduced mobility: prospective associations with falls and fractures in The Irish Longitudinal Study on Ageing
Desmond O Donnell, Roman Romero-Ortuno, Sean P Kennelly, Desmond O’Neill, Patrick O Donoghue, Amanda Lavan, Conal Cunningham, Paul McElwaine, Rose Anne Kenny, Robert Briggs
doi : 10.1093/ageing/afad005
Age and Ageing, Volume 52, Issue 2, February 2023, afad005
Orthostatic hypotension (OH), cognitive impairment (Cog) and mobility impairment (MI) frequently co-occur in older adults who fall. This study examines clustering of these three geriatric syndromes and ascertains their relationship with future falls/fractures in a large cohort of community-dwelling people ≥ 65 years during 8-year follow-up.
Serum sodium, cognition and incident dementia in the general population
Anna C van der Burgh, Anissa Pelouto, Sanne S Mooldijk, Adrienne A M Zandbergen, M Arfan Ikram, Layal Chaker, Ewout J Hoorn
doi : 10.1093/ageing/afad007
Age and Ageing, Volume 52, Issue 2, February 2023, afad007
Low serum sodium may be associated with cognitive impairment and dementia in the general population, but the data remain inconclusive. Therefore, we aimed to determine the association of low serum sodium with cognitive function and incident dementia in the general population.
Updating the British Geriatrics Society recommended undergraduate curriculum in geriatric medicine: a curriculum mapping and nominal group technique study
Grace M E Pearson, Rebecca Winter, Adrian Blundell, Tahir Masud, Joanna Gough, Adam L Gordon, BGS Undergraduate Curriculum Nominal Group , Emily J Henderson
doi : 10.1093/ageing/afac325
Age and Ageing, Volume 52, Issue 2, February 2023, afac325
medical education must adapt to meet the challenges and demands of an ageing population, ensuring that graduates are equipped to look after older patients with complex health and social care needs.
Adverse Childhood Experiences and frailty in later life: a prospective population-based cohort study
Menelaos M Dimitriadis, Hans W Jeuring, Radboud M Marijnissen, Thomas H Wieringa, Emiel O Hoogendijk, Richard C Oude Voshaar
doi : 10.1093/ageing/afad010
Age and Ageing, Volume 52, Issue 2, February 2023, afad010
The deficit accumulation method considers the ageing process underlying frailty as a random accumulation of health deficits.
Trajectories of self-reported hearing and their associations with cognition: evidence from the United Kingdom and United States of America
Katey Matthews, Piers Dawes, Rebecca Elliot, Neil Pendleton, Gindo Tampubolon, Asri Maharani
doi : 10.1093/ageing/afad017
Age and Ageing, Volume 52, Issue 2, February 2023, afad017
This study aimed to investigate the relationships between trajectories of change in self-reported hearing over eight years with subsequent effects on cognition, measured using episodic memory.
Higher dietary protein intake is associated with sarcopenia in older British twins
Mary Ni Lochlainn, Ruth C E Bowyer, Ailsa A Welch, Kevin Whelan, Claire J Steves
doi : 10.1093/ageing/afad018
Age and Ageing, Volume 52, Issue 2, February 2023, afad018
Sarcopenia, characterised by an accelerated loss of skeletal muscle mass and function, is associated with negative outcomes. This study aimed to evaluate factors associated with skeletal muscle strength, mass and sarcopenia, particularly protein intake, and to assess whether shared twin characteristics are important.
A prospective analysis examining frailty remission and the association with future falls risk in older adults in England
Katie Davies, Asri Maharani, Tarani Chandola, Terence W O’Neill, Chris Todd, Neil Pendleton
doi : 10.1093/ageing/afad003
Age and Ageing, Volume 52, Issue 2, February 2023, afad003
Previous research has shown older adults experience dynamic changes in frailty status. This study aimed to determine the occurrence of sustained frailty remission and how remission is associated with falls risk.
Comparison of sex differences in cognitive function in older adults between high- and middle-income countries and the role of education: a population-based multicohort study
Mikaela Bloomberg, Aline Dugravot, Andrew Sommerlad, Mika Kivimäki, Archana Singh-Manoux, Séverine Sabia
doi : 10.1093/ageing/afad019
Age and Ageing, Volume 52, Issue 2, February 2023, afad019
The extent to which education explains variations in sex differences in cognitive function between countries at different levels of economic development is unknown. We examined the role of education in sex differences in four cognitive domains in high- and middle-income countries.
Potential therapeutic targets for sarcopenia identified by Mendelian randomisation
Wei Jiang, Wenli Zhan, Luoqi Zhou, Minghao Dong, Liang Liu, Xiangshang Xu, Zhixin Cao
doi : 10.1093/ageing/afad024
Age and Ageing, Volume 52, Issue 2, February 2023, afad024
Identifying sarcopenia’s causally associated plasma proteins would provide potential therapeutic targets.
Building resilience and reversing frailty: a randomised controlled trial of a primary care intervention for older adults
John Travers, Roman Romero-Ortuno, John Langan, Fergal MacNamara, Darren McCormack, Christopher McDermott, Jude McEntire, Joanne McKiernan, Seán Lacey, Peter Doran, Dermot Power, Marie-Therese Cooney
doi : 10.1093/ageing/afad012
Age and Ageing, Volume 52, Issue 2, February 2023, afad012
There is a need for effective primary care interventions that help older people combat frailty and build resilience.
Long-term fine particular exposure and incidence of frailty in older adults: findings from the Chinese Longitudinal Healthy Longevity Survey
Yuebin Lv, Ze Yang, Lihong Ye, Meijie Jiang, Jinhui Zhou, Yanbo Guo, Yidan Qiu, Xinwei Li, Chen Chen, Aipeng Ju, Jun Wang, Chenfeng Li, Yang Li, Jiaonan Wang, Juan Zhang, John S Ji, Tiantian Li, Andrea A Baccarelli, Xu Gao, Xiaoming Shi
doi : 10.1093/ageing/afad009
Age and Ageing, Volume 52, Issue 2, February 2023, afad009
The association between fine particular matter (PM2.5) and frailty is less studied, and the national burden of PM2.5-related frailty in China is unknown.
Trends of polypharmacy among older people in Asia, Australia and the United Kingdom: a multinational population-based study
Hyesung Lee, Yeon-Hee Baek, Ju Hwan Kim, Tzu-Chi Liao, Wallis C Y Lau, Kenneth K C Man, Xiwen Qin, Stephen Wood, Jenni Ilomäki, J Simon Bell, Edward Chia-Cheng Lai, Miriam T Y Leung, Adrienne Y L Chan, Celine S L Chui, Ian C K Wong, Ju-Young Shin
doi : 10.1093/ageing/afad014
Age and Ageing, Volume 52, Issue 2, February 2023, afad014
Polypharmacy among older people represents a global challenge due to its association with adverse drug events. The reported prevalence of polypharmacy varies widely across countries, and is particularly high in Asian countries.
