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Ralph L. Sacco, 65, Dies: Stroke Expert With a Talent for Architectural Design.
Avitzur, Orly MD, MBA
doi : 10.1161/CIR.0000000000001127
Volume 147(9) pgs. 697-777,e625-e649 February 28, 2023
Cardiac Myosin Inhibitors: Unlocking Potential to Improve Treatment in Hypertrophic Cardiomyopathy.
Turer, Aslan Teyfik MD, MHS, MBA; Wang, Andrew MD
Incidental Coronary Artery Calcium: Opportunistic Screening of Previous Nongated Chest Computed Tomography Scans to Improve Statin Rates (NOTIFY-1 Project).
Sandhu, Alexander T. MD, MS; Rodriguez, Fatima MD, MPH; Ngo, Summer BS; Patel, Bhavik N. MD, MBA; Mastrodicasa, Domenico MD; Eng, David MS; Khandwala, Nishith MS; Balla, Sujana MBBS; Sousa, Doug BS; Maron, David J. MD
doi : 10.1161/CIRCULATIONAHA.122.062746
Coronary artery calcium (CAC) can be identified on nongated chest computed tomography (CT) scans, but this finding is not consistently incorporated into care. A deep learning algorithm enables opportunistic CAC screening of nongated chest CT scans.
When Opportunity Knocks: Capitalizing on Incidental Coronary Arterial Calcification.
Joshi, Parag H. MD, MHS; Nasir, Khurram MD, MPH, MSc; Navar, Ann Marie MD, PhD
The Prevalence and Association of Exercise Test Abnormalities With Sudden Cardiac Death and Transplant-Free Survival in Childhood Hypertrophic Cardiomyopathy.
Conway, Jennifer MD; Min, Sandar MBBS, MPH; Villa, Chet MD; Weintraub, Robert G. MD; Nakano, Stephanie MD; Godown, Justin MD; Tatangelo, Mark BA, PhD, MBA; Armstrong, Kathryn MBChB, MD; Richmond, Marc MD, MS; Kaufman, Beth MD; Lal, Ashwin K. MD; Balaji, Seshadri MBBS, PhD; Power, Alyssa MD; Baez Hernandez, Nathanya MD; Gardin, Letizia MD; Kantor, Paul F. MBBCh; Parent, John J. MD, MS; Aziz, Peter F. MD; Jefferies, John L. MD, MPH; Dragulescu, Andreea MD, PhD; Jeewa, Aamir MD; Benson, Lee MD; Russell, Mark W. MD; Whitehill, Robert MD; Rossano, Joseph MD; Howard, Taylor MD; Mital, Seema MD
doi : 10.1161/CIRCULATIONAHA.122.062699
Hypertrophic cardiomyopathy (HCM) can be associated with an abnormal exercise response. In adults with HCM, abnormal results on exercise stress testing are predictive of heart failure outcomes.
Peptide Vaccine Against ADAMTS-7 Ameliorates Atherosclerosis and Postinjury Neointima Hyperplasia.
Ma, Zihan PhD ,,*; Mao, Chenfeng PhD ,,,*; Chen, Xiao PhD; Yang, Shiyu BS; Qiu, Zhihua PhD; Yu, Baoqi PhD; Jia, Yiting PhD; Wu, Chao PhD; Wang, Yiyi PhD; Wang, Yuhui PhD; Gu, Rui PhD; Yu, Fang MSc; Yin, Yanhui PhD; Wang, Xian PhD; Xu, Qingbo PhD; Liu, Chuanju PhD; Liao, Yuhua PhD; Zheng, Jingang PhD; Fu, Yi MBBS, PhD; Kong, Wei MD, PhD
doi : 10.1161/CIRCULATIONAHA.122.061516
The metalloprotease ADAMTS-7 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 7) is a novel locus associated with human coronary atherosclerosis.
Targeting ADAMTS-7: A Vaccination Against Atherosclerosis-and Its Complications?.
Kessler, Thorsten MD; Schunkert, Heribert MD
Interleukin-33 Mediates Cardiomyopathy After Acute Kidney Injury by Signaling to Cardiomyocytes.
Florens, Nans MD, PhD; Kasam, Rajesh K. PhD; Rudman-Melnick, Valeria PhD; Lin, Suh-Chin PhD; Prasad, Vikram PhD; Molkentin, Jeffery D. PhD
doi : 10.1161/CIRCULATIONAHA.122.063014
Acute kidney injury (AKI) is a short-term life-threatening condition that, if survived, can lead to renal insufficiency and development of chronic kidney disease. The pathogenesis of AKI and chronic kidney disease involves direct effects on the heart and the development of hypertrophy and cardiomyopathy.
Declining Risk of Sudden Cardiac Death in Heart Failure: Fact or Myth?.
Leyva, Francisco MD; Israel, Carsten W. PhD; Singh, Jagmeet MD, PhD
doi : 10.1161/CIRCULATIONAHA.122.062159
AB The notion that the risk of sudden cardiac death (SCD) in patients with heart failure (HF) is declining seems to be gaining traction. Numerous editorials and commentaries have suggested that SCD, specifically arrhythmic SCD, is no longer a significant risk for patients with HF on guideline-directed medical therapy.
Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice.
Pan, Chang MD; Herrero-Fernandez, Beatriz MSc; Borja Almarcha, Celia MSc; Gomez Bris, Raquel MSc; Zorita, Virginia MSc; Saez, Angela PhD; Maas, Sanne Lidewij MSc; Perez-Olivares, Laura MSc; Herrero-Cervera, Andrea PhD; Lemnitzer, Patricia BSc; van Avondt, Kristof PhD; Silvestre-Roig, Carlos PhD; Gonzalez-Granado, Jose Maria PhD; Chevre, Raphael PhD *,,; Soehnlein, Oliver MD, PhD *,,,
Letter by Du et al Regarding Article, "Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults".
Du, Lixin MD; Wang, Pan BS; Chen, Hongwei BS
Response by Lee and Giovannucci to Letter Regarding Article, "Long-Term Leisure-Time Physical Activity Intensity and All-Cause and Cause-Specific Mortality: A Prospective Cohort of US Adults".
Lee, Dong Hoon ScD; Giovannucci, Edward L. MD, ScD
Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association.
Goldberg, Joshua B. MD, Chair; Giri, Jay MD, MPH, FAHA, Vice Chair; Kobayashi, Taisei MD; Ruel, Marc MD, MPH, FRCSC, FAHA; Mittnacht, Alexander J.C. MD; Rivera-Lebron, Belinda MD, MS; DeAnda, Abe Jr MD, FAHA; Moriarty, John M. MD; MacGillivray, Thomas E. MD; on behalf of the American Heart Association Council on Cardiovascular Surgery and Anesthesia; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease
doi : 10.1161/CIR.0000000000001117
AB Acute pulmonary embolism is the third leading cause of cardiovascular death, with most pulmonary embolism-related mortality associated with acute right ventricular failure.
Correction to: A New Era in Cardiac Rehabilitation Delivery: Research Gaps, Questions, Strategies, and Priorities.
Correction to: Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2022 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2022.
