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A Shared Genetic Signature for Common Chronic Pain Conditions and its Impact on Biopsychosocial Traits
Scott F. Farrell,* ,y,z Pik-Fang Kho,x,{,k Mischa Lundberg,**,yy Adrian I. Campos,zz,xx Miguel E. Renterıa,xx Rutger M.J. de Zoete,{{ Michele Sterling,*,y Trung Thanh Ngo,*,2 and Gabriel Cuellar-Partida
doi : 10.1016/j.jpain.2022.10.005
Volume 24, Issue 3, March 2023, Pages 369-386
The multiple comorbidities & dimensions of chronic pain present a formidable challenge in disentangling its aetiology.
Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks−American Pain Society−American Academy of Pain Medicine Pain Taxonomy Diagnostic Criteria for Acute Needle Pain
William T. Zempsky,*,y Marsha Campbell-Yeo,z,x,{ Christine T. Chambers,x,{ Lindsey L. Cohen,k Lucia Gagliese, #, **,yy Charlie H.T. Kwok,zz Tuan Trang,zz Bonnie Stevens,xx,{{ Anna Taddio,kk Terri Voepel-Lewis, ##, *** and Neil L. Schechter
doi : 10.1016/j.jpain.2022.09.018
Volume 24, Issue 3, March 2023, Pages 387-402
Needle procedures are among the most common causes of pain and distress for individuals seeking health care. While needle pain is especially problematic for children needle pain and associated fear also has significant impact on adults and can lead to avoidance of appropriate medical care.
Definitions of Chronic Low Back Pain From a Scoping Review, and Analyses of Narratives and Self-Reported Health of Adults With Low Back Pain
Patricia M. Herman,* Nabeel Qureshi,* Susan D. Arick,* Maria O. Edelen,y Ron D. Hays,*,z Anthony Rodriguez,y Rebecca L. Weir,* and Ian D. Coulter
doi : 10.1016/j.jpain.2022.10.012
Volume 24, Issue 3, March 2023, Pages 403-412
Among those with low back pain (LBP), individuals with chronic LBP (CLBP) face different treatment recommendations and incur the majority of suffering and costs. However, the way CLBP has been defined varies greatly.
Nocturnal Delta Power is Associated With Lower Next-Day Pain But Not Pain Catastrophizing: Results From a Cohort of Female Participants With Temporomandibular Joint Pain
Matthew J. Reid,* Abhishek Dave,y Darlynn M. Rojo-Wissar,z Chung Jung Mun,* ,x Sheera F. Lerman,* Luis Buenaver,* Howard Tennen,{ Jennifer Haythornthwaite,* Claudia M. Campbell,* Patrick Finan,* and Michael T. Smith
doi : 10.1016/j.jpain.2022.10.002
Volume 24, Issue 3, March 2023, Pages 413-425
Existing data demonstrate reduced delta power during sleep in patients with depression and chronic pain. However, there has been little examination of the relationship between delta power and pain-reports, or pain-catastrophizing.
Path Analysis Models Integrating Psychological, Psycho-physical and Clinical Variables in Individuals With Tension-Type Headache
Bernard X.W. Liew,* Marıa Palacios-Ce~na,y Marco Scutari,z Stella Fuensalida-Novo,y Angel Guerrero-Peral,x Carlos Ordas-Bandera,{ Juan A. Pareja,k and Cesar Fernandez-de-las-Pe~nas
doi : 10.1016/j.jpain.2022.10.003
Volume 24, Issue 3, March 2023, Pages 426-436
Tension type headache (TTH) is a prevalent but poorly understood pain disease. Current understanding supports the presence of multiple associations underlying its pathogenesis. Our aim was to compare competing multivariate pathway models that explains the complexity of TTH.
Chronic Struggle: An Institutional Ethnography of Chronic Pain and Marginalization
Fiona Webster,*,y Laura Connoy,* Abhimanyu Sud,y,z,x Kathleen Rice,{ Joel Katz,k,** Andrew D. Pinto,y,z,yy Ross Upshur,y,z and Craig Dale
doi : 10.1016/j.jpain.2022.10.004
Volume 24, Issue 3, March 2023, Pages 437-448
There have been several recent calls to re-think chronic pain in response to the growing awareness of social inequities that impact the prevalence of chronic pain and its management. This in turn has resulted in new explorations of suffering as it relates to pain. While laudable, many of these clinically oriented accounts are abstract and often fail to offer a critical theoretical understanding of social and structural inequities.
LncRNA XR_351665 Contributes to Chronic Pain-Induced Depression by Upregulating DNMT1 via Sponging miR-152-3p
Xiaobao Ding,*,# Yuwen Lin,*,# Binbin Yan,*,# Xiaowei Jiao,* Qiang Liu,y Huihui Miao,z Yuqing Wu,y and Chenghua Zhou*
doi : 10.1016/j.jpain.2022.10.006
Volume 24, Issue 3, March 2023, Pages 449-462
Chronic pain is frequently comorbid with depression. However, the mechanisms underlying chronic pain-induced depression remain unclear.
Spinal CircKcnk9 Regulates Chronic Visceral Hypersensitivity of Irritable Bowel Syndrome
Zhong Chen,y Yuan Liu,y Xianhe Wu,y Wei Lin,z Zihan Liu,y Yang Huang,y Yu Chen,y Ying Tang,y Aiqin Chen,y and Chun Lin
doi : 10.1016/j.jpain.2022.10.007
Volume 24, Issue 3, March 2023, Pages 463-477
Dysregulation of circular RNAs (circRNAs) has been reported to be functionally associated with chronic pain, but it is unknown whether and how circRNAs participate in visceral hypersensitivity.
Circulating Polyunsaturated Fatty Acids and Pain Intensity in Five Chronic Pain Conditions
Anne E. Sanders,* E. Diane Weatherspoon,y Brandie M. Ehrmann,y Paul S. Soma,y Saame R. Shaikh,z John S. Preisser,x Richard Ohrbach,{ Roger B. Fillingim,k, ** and Gary D. Slade
doi : 10.1016/j.jpain.2022.10.008
Volume 24, Issue 3, March 2023, Pages 478-489
Pain intensity is well-known to be influenced by a wide range of biobehavioral variables. Nutritional factors, however, have not been generally considered for their potential importance.
The Effects of Recovery Sleep on Experimental Pain
Cindy Stroemel-Scheder, and Stefan Lautenbacher
doi : 10.1016/j.jpain.2022.10.009
Volume 24, Issue 3, March 2023, Pages 490-501
Prevalence of Phantom Phenomena in Congenital and Early-Life Amputees
Martin Diers,*,y Xaver Fuchs,*,z Robin Bekrater-Bodmann
doi : 10.1016/j.jpain.2022.10.010
Volume 24, Issue 3, March 2023, Pages 502-508
Phantom limb pain (PLP) is a common consequence of the amputation of a limb. Persons with congenital limb absence (congenital amputees) or an acquired limb amputation at an early age seem to rarely experience PLP. However, the number of available studies and their sample sizes are low.
Green Light Exposure Elicits Anti-inflammation, Endogenous Opioid Release and Dampens Synaptic Potentiation to Relieve Post-surgical Pain
Laurent F. Martin,*,y Kevin Cheng,* Stephanie M. Washington,y Millie Denton,y Vasudha Goel,{ Maithili Khandekar,y Tally M. Largent-Milnes,* Amol Patwardhan,*,y,z,x and Mohab M. Ibrahim
doi : 10.1016/j.jpain.2022.10.011
Volume 24, Issue 3, March 2023, Pages 509-529
Light therapy improves multiple conditions such as seasonal affective disorders, circadian rhythm dysregulations, and neurodegenerative diseases. However, little is known about its potential benefits in pain management.
Responsiveness and Minimal Important Change of the PROMIS Pain Interference Item Bank in Patients Presented in Musculoskeletal Practice
Wouter Schuller,* ,y,z Caroline B. Terwee,* ,y Berend Terluin,x Daphne C. Rohrich,{ Raymond W.J.G. Ostelo,â•‘, ** and Henrica C.W. de Vet
doi : 10.1016/j.jpain.2022.10.013
Volume 24, Issue 3, March 2023, Pages 530-539
We evaluated the responsiveness of the Patient Reported Outcome Information System Pain Interference item bank in patients with musculoskeletal pain by testing predefined hypotheses about the relationship between the change scores on the item bank, change scores on legacy instruments and Global Ratings of Change (GRoC), and we estimated Minimal Important Change (MIC).
Suppression of the Excitability of Rat Nociceptive Primary Sensory Neurons Following Local Administration of the Phytochemical, Quercetin
Ryou Toyota, Haruka Ito, Yukito Sashide, and Mamoru Takeda
doi : 10.1016/j.jpain.2022.10.014
Volume 24, Issue 3, March 2023, Pages 540-549
Although the modulatory effect of quercetin on voltage-gated Na, K, and Ca channels has been studied in vitro, the in vivo effect of quercetin on the excitability of nociceptive primary neurons remains to be determined.
Pain-Related Suffering
Zakir Uddin
doi : 10.1016/j.jpain.2022.11.012
Volume 24, Issue 3, March 2023, Pages 550-551
Moving Closer to An Inclusive Definition of Pain-related Suffering and Targeted Care
Peter StilwellAnne HudonKeith MeldrumM. Gabrielle PagVirginia McIntyreTimothy H. Wideman
doi : 10.1016/j.jpain.2022.11.011
Volume 24, Issue 3, March 2023, Pages 552-553
