Journal of Cosmetic Dermatology




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Issue Information

doi : 10.1111/jocd.15054

Volume 22, Issue 3

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JCD March 2023 Editorial

Michael H. Gold M.D.

doi : 10.1111/jocd.15687

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Clinical course of psoriasis patients that discontinued biologics during the COVID-19 pandemic

Filiz TopaloÄŸlu Demir MD, Algün Polat Ekinci MD, Sema Aytekin MD, Zeynep Topkarcı MD, Melek Aslan Kayıran MD, TuÄŸba Özkök Akbulut MD, Ä°lteriÅŸ OÄŸuz Topal MD, Sezgi Sarıkaya Solak MD, Asude Kara Polat MD, AyÅŸe Serap KaradaÄŸ MD

doi : 10.1111/jocd.15638

Since psoriasis is a chronic disease, it is not recommended to discontinue the treatment agents used. However, in real life, the treatment of psoriasis patients may be interrupted for various reasons. During the pandemic period, the treatment of many patients was also interrupted.

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Comment on “Cutaneous adverse reactions of COVID-19 vaccines: A systematic review�

Orla McFeely MB, BAO, BCh, MRCPI, Liana Victory MB, BAO, BCh, Emily Pender MB, BAO, BCh, MRCPI, Emma Shudell MB, BAO, BCh, MRCPI

doi : 10.1111/jocd.15612

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Pediatric alopecia areata following COVID-19 infection

Astrid Herzum MD, Gianmaria Viglizzo MD, Lodovica Gariazzo MD, Ehab Garibeh MD, Corrado Occella MD

doi : 10.1111/jocd.15618

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Rethinking of positive effects of eggs on hair in East Asia

Jina Jung BA, Ki Han Kwon PhD

doi : 10.1111/jocd.15469

Our bodies are a collection of nutrients. For healthy body production and activities, good nutrients must be balanced and supplied steadily. However, as modern people eat more irregular meals and fast food, they are running out of nutrients needed by the human body.

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Subcision in acne scarring: A review of clinical trials

Najmeh Ahramiyanpour MD, Fatemeh Rastaghi MD, Seyed Yasamin Parvar MS, Ali Karimi Sisakht MS, Seyed Ali Hosseini MD, Maliheh Amani MD

doi : 10.1111/jocd.15480

Post-acne scarring is the most common permanent consequence of acne vulgaris. Subcision is an intervention in which a needle or blunt cannula is inserted under the scar and moved back and forth to cut fibrotic strands and form new connective tissue, thereby elevating the atrophic scars.

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Determinants of consumer adoption of halal cosmetics: A systematic literature review

Raihan Mohd Isa BA, Saadan Man PhD, Noor Naemah Abdul Rahman PhD, Atiqah Aziz MSc

doi : 10.1111/jocd.15486

The global halal cosmetics market is projected to grow during the forecast period. However, the factors that influenced consumers in the world to opt for halal cosmetics remain ambiguous.

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“The efficacy and adverse effects of treatment options for facial pores: A review article�

Seyedeh Yasamin Parvar, Maliheh Amani MD, Mohadeseh Shafiei MD, Fatemeh Rastaghi MD, Seyed Ali Hosseini MD, Najmeh Ahramiyanpour MD

doi : 10.1111/jocd.15502

Skin pores are enlarged openings of the pilosebaceous follicles that can be affected by age, gender, genetics, exposure to UV light, ethnicity, and sebum secretion. Many treatment modalities reduce facial pores’ count and area, including oral and topical medications as well as different wavelengths of lasers.

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A narrative review on subcutaneous injection components used for alopecia

Jung Hyun Kim PhD

doi : 10.1111/jocd.15522

Studies reporting the development and effectiveness of topical agents for alopecia are available. However, it was difficult to demonstrate a direct advantage of subcutaneous injection rather than topical application. Since existing articles lack information, future studies are needed to solve these problems and to narrow the knowledge gap.

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Case series of tongue necrosis from vascular complications after chin augmentation with hyaluronic acid: Potential pathophysiology and management

Wilai Thanasarnaksorn MD, Apichaya Thanyavuthi MD, Piyatida Prasertvit MD, Siwakorn Rattanakuntee DDS, MSc, FRCDS, Benrita Jitaree PhD, Atchima Suwanchinda MD, MSc

doi : 10.1111/jocd.15475

Even though the chin is considered a safe injection area for facial filler augmentation, tongue necrosis is a rare complication in this area.

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The effect of combined of hyaluronic acid dermal filler and microfocused ultrasound treatment: A clinicopathological study

Vasanop Vachiramon MD, MSc, Suthinee Rutnin MD, Chanikarn Patcharapojanart MD, MSc, Natthaphon Chittasirinuvat MD, MSc

doi : 10.1111/jocd.15498

Microfocused ultrasound (MFU) and hyaluronic acid (HA) filler injection are increasingly popular aesthetic procedures. HA filler injection is generally recommended after MFU if combined treatment is required in a single visit. However, data regarding the safe and optimal time of MFU treatment after HA injection is still limited.

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The effect of combined hyaluronic acid filler injection and radiofrequency treatment: A clinic histological analysis

Natthachat Jurairattanaporn MD, MSc, Watinee Amornpetkul MD, MSc, Suthinee Rutnin MD, Vasanop Vachiramon MD

doi : 10.1111/jocd.15509

Hyaluronic acid (HA) filler injections have increased in popularity. They are usually performed in combination with other treatment modalities, including lasers and energy-based devices, to enhance cosmetic results.

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Association of PDO threads and technologies�Facial treatment protocols

Clessya Rocha Miranda MD

doi : 10.1111/jocd.15530

Aging is part of the immutable characteristics of the human being, and the search for treatments to alleviate the undesirable effects of aging is frequent in the dermatological office.

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Efficacy and safety of micro-needling combined with topical 5-fluorouracil and excimer light vs. excimer light alone in treatment of non-segmental vitiligo: A comparative study

Mohammad A. Saad MSc, Khaled Mohamed Tawfik MD, Hazem L. Abdelaleem MD

doi : 10.1111/jocd.15481

Vitiligo is one of the most challenging dermatological diseases with little improvement promises. Various modalities of treatment both medical and surgical have been used in the treatment of vitiligo.

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A combination treatment of drug-laser-photon for melasma: A retrospective study of clinical cases

Ying Li BSMed, Wei-Na Shao BSMed, Qing-Qing Fang PhD, Wan-yi Zhao MSc, Shi-qin Wang BSMed, Li-Hong Wu MSc, Yan-Yan Hu BSMed, Xiao-feng Wang PhD, Ya-Nan Xue MSc, Li Chen MSc, Wei-Qiang Tan MD

doi : 10.1111/jocd.15488

Combinational therapy such as taking tranexamic acid while using laser treatment has been proved potential efficacy by many experiments. However, there is few research which contains large samples and consistent observations.

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The efficacy and safety of the combination of photobiomodulation therapy and pulsed electromagnetic field therapy on androgenetic alopecia

Mi Soo Choi MD, Byung Cheol Park MD, PhD

doi : 10.1111/jocd.15490

Photobiomodulation therapy (PBMT) appears to be safe and effective for hair loss. Pulsed electromagnetic field therapy (PEMF) also has a positive biological effect on hair re-growth.

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Fractional carbon dioxide laser versus combined fractional CO2 laser and platelet rich plasma in treatment of facial wrinkles: A comparative split face study

Wael M. Seoudy MD, Haitham S. El Messallamy Msc, Sahar S. Youssef MD, Marwa S. E. Zaki MD

doi : 10.1111/jocd.15500

Wrinkles are the most visible sign in skin aging and for which many people seek different aesthetic procedures. Treatment options varies from invasive to non-invasive procedures.

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Safety and efficacy of CO2 dot matrix laser combined with platelet-rich plasma on depressed scar after acne vulgaris and influencing factors of its repair effect: A retrospective analysis

Rong Guo MM, Wenxia Xuan MM, Xiao He MM, Kai Xu MM

doi : 10.1111/jocd.15501

Acne vulgaris (AV) is the most pervasive inflammatory disease of hair follicle and sebaceous gland in the dermatology department, and depressed scar (DS) is the most common and serious sequela of AV.

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Directions of hyaluronic acid application in cosmetology

Piotr Ratajczak PhD, Oliwia Maciejak BSc, Dorota Kopciuch PhD, Anna Paczkowska PhD, Tomasz Zaprutko PhD, Krzysztof Kus PhD

doi : 10.1111/jocd.15485

Hyaluronic acid is a naturally occurring substance in the human body. It is a component of the intercellular matrix of the dermis and is often used as a raw material in cosmetology.

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Applying sunscreen SPF 50 with high antioxidant capacity during fifteen days improves the dermis echogenicity and reduces the reddish skin undertone

Victor Hugo Pacagnelli Infante PhD, Patrícia Maria Berardo Gonçalves Maia Campos PhD

doi : 10.1111/jocd.15528

Of the many effects induced by UV radiation on the skin, erythema is one of the most well-known features, which is a cutaneous inflammatory reaction correlated with acute photodamage. The utilization of sunscreen may reduce this process.

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Efficacy and safety of innovative acne scar serum in Indian patients (ESTEEM India study)

Sanjiv Kandhari MD, Anil Ganjoo MD, Abhay Talathi MD, DNB, Sanjeev Aurangabadkar MD, Satish Bhatia MD, Apratim Goel MD, DNB, Chetan Y. Patil MD

doi : 10.1111/jocd.15536

Scarring is a common and undesirable outcome of acne vulgaris. There are limited effective topical formulations for acne scar treatment. The investigational product, acne scar serum (HEXILAK® Acne Scar Serum) is latest topical formulation developed for treatment of acne scar with unique ingredients, Kollaren and Exo-T.

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Reliability of a standardized tool for evaluating severity of cellulite in the female posterior thigh

Thellie Ponto PhD, Heather A. E. Benson PhD, Anthony Wright PhD

doi : 10.1111/jocd.15487

Numerous products and minimally-invasive procedures are available to reduce cellulite. However, there are a limited number of tools to evaluate the effects of these interventions and some are relatively complex to implement.

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Stab access fascia suspension lift: A facelift technique without skin excision and visible scar

Xi Fu MD, Jia Qiao MD, Jianfeng Liu MD, Ying Chen MD, Qi Jin MD, Shixing Xu MD, Bing Yu MD, Lai Gui MD, Feng Niu MD

doi : 10.1111/jocd.15496

Traditional middle and lower facelifts are not suitable for patients with mild skin laxity or who wish to avoid incision scars.

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Flexible application of scar tissue flaps in scar contracture release surgery: A retrospective study

Xiaojing Ge MD, Yute Sun MD, Youzhi Tang MD, Fang Zhou MD, Gang Yao MD, Xin Su MD

doi : 10.1111/jocd.15505

Complete release of scar contracture often relies on surgery, but if the surgery injures normal skin tissue triggers new wounds and scarring, which adds insult to injury for the patient.

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Topical garlic treatment for verruca plana triggers Koebner phenomenon: A case report

Tianhang Yu MD, Jiaozi Che MD, Jikai Song MD, Xinsuo Duan MD, Jie Yang MD, PhD

doi : 10.1111/jocd.15507

Verruca plana is a benign proliferation of the skin caused by human papilloma virus (HPV) infection. Fresh garlic can serve as an alternative therapy, and it has shown considerable effectiveness as a topical treatment for verruca plana.

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Comparative study between nail retraining with gauze bandaging and the nail remodeling with acrylics as a conservative treatment for stage I and IIa onychocryptosis

María Teresa García Martínez DP, Beatriz Gómez-Gabriel DP, Alfonso Martínez-Nova PhD, Pilar Nieto Gil PhD

doi : 10.1111/jocd.15512

Onychocryptosis is one of the most prevalent onychopathies, being a frequent reason for consultation in podiatric clinical practice. Conservative treatments are the first therapeutic choice, with nail remodeling using clotrimazole gel emerging as an alternative, although its medium-term effectiveness is unknown.

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Comparing the application of various engineered xenografts for skin defects: A systematic review

Antoine Salloum MD, Nagham Bazzi MD, Stephen Squires MD, Thomas Chu MD, Paul Benedetto MD, FAAD, Anthony Benedetto DO, FACP, FACMS

doi : 10.1111/jocd.15517

Xenografts are a now a cornerstone in the management of wound dressings. Promising results were achieved since 1960 in the application of skin substitute for skin defects.

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Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids

Alexa J. Cohen BS, Sahithi Talasila BS, Bojan Lazarevic BA, Lauren Banner BS, Laura Gleason BS, Kabir Malkani MD, Jouni Uitto MD, PhD, Neda Nikbakht MD, PhD

doi : 10.1111/jocd.15520

Keloids are common and have significant negative effects on quality of life. There is a need for more effective treatment approaches for keloids.

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Pyramidal multiple-theory (multi-type, multi-method and multi-layer) for facial fat grafting

Hao Hu MD, Yingshen Shi MD, Yuxin Qian MD, Xiaoyan Yu MD, Antang Liu MD, Facheng Li MD, Hua Jiang MD, Hui Wang MD

doi : 10.1111/jocd.15525

Age-related changes to the face pertinent anatomy and important aspects of autologous fat grafting have been widely applied in facial rejuvenation. Various types of autologous fat products (Macrofat, Microfat, SEFF, nanofat, and SVF-gel) with different properties and applicabilities have been introduced and available for surgeons.

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Acquired port-wine stains: A report of two cases and review of the literature

Elie Saliba MD, Sara Yumeen MD, Zeina Tannous MD

doi : 10.1111/jocd.15526

Acquired port-wine stains (APWS) are rare vascular malformations that share the same clinical and histological features as their congenital counterparts. Rare cases of AWPS secondary to trauma or in association with medications have been reported in the literature.

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Differences in clinical characteristics of rosacea across age groups: A retrospective study of 840 female patients

Fengjuan Yang MD, Lian Wang PhD, Huidi Shucheng PhD, Xian Jiang PhD

doi : 10.1111/jocd.15470

Aging remains a common influencing factor for many diseases. Previous studies have shown that age is significantly associated with rosacea among female cases and that the incidence of rosacea increases with age. However, previous studies did not specifically analyze the clinical characteristics of different age groups.

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Flow cytometry as an alternative method to evaluate genotoxicity of natural cosmetic actives

Andreza R. Ueoka MD, Bianca S. Sufi MD, Wagner V. Magalhães MD, Liliam Fernandes PhD, Newton Andreo-Filho PhD, Vania R. Leite-Silva PhD, Patricia S. Lopes PhD

doi : 10.1111/jocd.15473

Alternative in vitro methods are important, as there is a call to ban the use of animals in cosmetics research.

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Association between vitamin D receptor polymorphisms and vitiligo susceptibility: An updated meta-analysis

Young Ho Lee MD, PhD, Gwan Gyu Song MD, PhD

doi : 10.1111/jocd.15474

Vitamin D receptor (VDR) polymorphisms may play an important role in the vitiligo susceptibility. There have been many studies looking at the associations between VDR polymorphisms and vitiligo risk, but the conclusions are still up for debate.

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The structural relationship between job satisfaction and organizational commitment of beauty industry employees

Eun Jung Shin MA, Ki Han Kwon PhD

doi : 10.1111/jocd.15479

Based on the analysis results that can further enhance organizational satisfaction and response to changes in the employment environment of cosmetic employees and workers through organizational commitment and turnover intention of cosmetic.

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Evaluation of subclinical atherosclerosis in rosacea patients by flow-mediated dilatation method

Nazlı Caf MD, TuÄŸba Özkök Akbulut MD, Mehmet Mustafa Can MD, Mustafa Sarı MD, AyÅŸe Nilhan Atsü MD, Zafer TürkoÄŸlu MD

doi : 10.1111/jocd.15492

Rosacea may contribute to the development of cardiovascular (CV) diseases by causing endothelial dysfunction (ED), which is known to be the initial step of atherosclerosis, due to its inflammatory features.

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Evaluation of plasma zonulin level and its relationship with inflammatory cytokines in patients with vitiligo

Selami Arslan MD, Nihal Altunisik MD, Dursun Turkmen MD, Muhammed M. Uremis PhD, Serpil Sener MD, Yusuf Turkoz MD

doi : 10.1111/jocd.15493

It has been proven that there is an increase in intestinal permeability in some autoimmune diseases. In our study, we purposed to assess intestinal permeability in vitiligo disease by looking at zonulin levels. At the same time, we aimed to examine the correlation of inflammatory cytokines and lipopolysaccharide (LPS) levels with zonulin.

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Liquiritigenin reverses skin aging by inhibiting UV-induced mitochondrial uncoupling and excessive energy consumption

Qi Lu BSc, Lin-feng Zou BSc, Yuan-zhen Gao BSc, Ting Ye Bsc, Meng-jiao Li BSc, Yu-Kun Zhang BSc, Bing Liang PhD, Wenshe Sun PhD, Dong-ming Xing PhD

doi : 10.1111/jocd.15506

The accumulation of reactive oxygen species (ROS) generated by UV radiation can lead to lipid, protein, nucleic acid, and organelle damage, one of the core mechanisms mediating skin aging. In the photoaging process, how ROS drives the imbalance of the body's complex repair system to induce senescence-like features is not fully understood.

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Characterization of a live Cutibacterium acnes subspecies defendens strain XYCM42 and clinical assessment as a topical regimen for general skin health and cosmesis

Mun Su Rhee PhD, Mona L. Alqam MD, Brian C. Jones PhD, Sasima Phadungpojna PhD, Doris Day MD, Thomas M. Hitchcock PhD

doi : 10.1111/jocd.15510

When formulating topical products to treat skin diseases and addressing general skin health and cosmesis, most of the focus has traditionally been placed on how any given ingredient may impact the structure, function, and health of human skin elements.

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Enhanced intradermal delivery of Dragon's blood in biocompatible nanosuspensions hydrogel patch for skin photoprotective effect

Shasha Wang, Yuxin Shi, Jiapeng Ma, Zhuofei Ye, Miaomiao Yao, Jing Shang, Jianping Liu

doi : 10.1111/jocd.15515

Dragon's Blood is a member of the Chinese medicinal herb, having anti-oxygen and anti-inflammatory activity for the photoprotective effect. However, the poor water solubility of raw Dragon's Blood powder has limited its intradermal delivery process.

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Abnormal nuclear expression of aquaporin-3 in lesional and perilesional skin of vitiligo patients: A novel immunohistochemical finding

Hend Gamil MD, Magda Assaf MD, Mohamad Khater MD, Manal Fawzy MD

doi : 10.1111/jocd.15518

Vitiligo is a skin disease characterized by a complex etiopathogenesis. Keratinocyte apoptosis may play a role in vitiligo pathogenesis. Aquaporin-3 (AQP-3) is an aqua-glyceroporin that controls keratinocyte proliferation and differentiation.

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Results of the patch tests with European baseline series in children: Five years of experience from a single center in Turkey and a review of the literature

Sümeyye Altıntaş Kakşi MD, Filiz Cebeci Kahraman MD, Necmettin Akdeniz MD, Tunç Özen MD

doi : 10.1111/jocd.15531

Pediatric allergic contact dermatitis (ACD) is increasingly prevalent. Patch testing is the gold-standard diagnostic method.

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Evaluation of hematological parameters in patients using systemic isotretinoin with diagnosis of acne vulgaris

Elif Demirci Saadet MD, Ugur Sahin MD

doi : 10.1111/jocd.15532

Oral isotretinoin is the most effective treatment option in patients with acne. However, it can cause various hematologic and biochemical abnormalities. This study aimed to evaluate hematologic abnormalities during oral isotretinoin treatment in patients with acne.

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Comparison of NB-UVB combination therapy regimens for vitiligo: A systematic review and network meta-analysis

Baohua Zhu MD, Chengjiang Liu MD, Ph.D, Lan Zhang MD, Jun Wang MS, Mingling Chen MD, Yuegang Wei BM

doi : 10.1111/jocd.15534

Vitiligo was an autoimmune disease and some guidelines for the management of vitiligo encouraged the use of NB-UVB combination therapies to enhance repigmentation.

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Impulsivity in patients with acne excoriee

Çağrı Öğüt MD, Neslihan Demirel Öğüt MD

doi : 10.1111/jocd.15535

Impulsivity is the tendency to make decisions and act quickly without adequate planning and anticipating risks. Impulsivity is among the core symptoms of many psychiatric disorders. In addition, impulsivity can affect the course of various diseases shaped by behaviors.

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The use of Janus kinase inhibitors and narrowband ultraviolet B combination therapy in non-segmental vitiligo

Faraz Yousefian DO, Sujitha Yadlapati MD, John C. Browning MD, FAAD, FAAP, MBA

doi : 10.1111/jocd.15537

Vitiligo is a depigmentation disorder of the skin that occurs secondary to the destruction of melanocytes by an immune-mediated process. Vitiligo clinically presents with depigmented macules and patches, most commonly on the face, acral sites, and genitalia.

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Exploring the mechanism of MP gel against skin photoaging based on network pharmacology, molecular docking, and experimental validation

Jinfan Xu MSc, Guodong Wu MMed, Xianglin Yu MSc, Zhiheng Dong PhD, Jibiao Yan BSc, Lan Wu MSc, Lidao Bao PhD, Quanli Liu MSc

doi : 10.1111/jocd.15542

Long-term and high exposure to UV radiation can lead to the development of skin photoaging diseases. Therefore, there is an ongoing need for more natural and safe drugs to prevent or treat skin photoaging diseases.

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Atypical case of cutaneous Rosai-Dorfman disease

Teresa Battista MD, Gabriella Fabbrocini Prof-MD, Lorenzo Martora MD, Fabrizio Martora MD

doi : 10.1111/jocd.15478

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“Filter dysmorphia�: An emerging phenomenon in cosmetic dermatology

Maryam Sadat Sadati MD, Roya Radanfar MD

doi : 10.1111/jocd.15483

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Eruptive syringomas: Summary of ninety cases and a brief literature review

Hao Lei MM, Ziyang Wang MD, Xinyu Ma MM, Zhaohan Zhang MM, Yiguo Feng MD, PhD, Yan Zheng MD, PhD

doi : 10.1111/jocd.15489

Eruptive syringomas is a rare variant of syringoma, which is a benign adenoma differentiated from the terminal ducts of the eccrine glands. Nowadays, it's widely valued because of obvious skin lesions, large scope of influence, and high misdiagnosis rate.

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Using methotrexate in the treatment of advanced vitiligo

Alana Tavitova PhD, Yan Valle PhD, Konstantin Lomonosov PhD

doi : 10.1111/jocd.15524

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Unraveling the hidden epidemic of mask related acne/maskne: An observational study

Aakanksha Arora MBBS, Alpana Mohta MD, DNB, Rajesh Datt Mehta MD

doi : 10.1111/jocd.15527

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Idiopathic hemifacial atrophy successfully treated with hyaluronic acid filler: About two new cases

Kouki Chaima MD, Mseddi Madiha PhD, Turki Hamida PhD

doi : 10.1111/jocd.15529

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A case of erythrodermic psoriasis rapidly and successfully treated with Bimekizumab

Matteo Megna MD, Teresa Battista MD, Luca Potestio MD, Angelo Ruggiero MD, Virginia Ventura MD, Gabriella Fabbrocini MD, Vincenzo Picone MD

doi : 10.1111/jocd.15543

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