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The effect of bone particle size on the histomorphometric and clinical outcomes following lateral ridge augmentation procedures: A randomized double-blinded controlled trial
Hussein S. Basma, Muhammad H. A. Saleh, Nico C. Geurs, Peng Li, Andrea Ravidà, Hom-Lay Wang, Ramzi V. Abou-Arraj
doi : 10.1002/JPER.22-0212
The aim of this randomized clinical trial was to clinically and histologically compare the amount and quality of bone gained after lateral ridge augmentation (LRA) procedures performed using small-particle (SP)-size (250–1000 Î¼m) versus large-particle (LP)-size (1000–2000 Î¼m) size corticocancellous bone allografts at 6 months following surgical intervention.
High prevalence of periodontitis in children and adolescents with type 2 diabetes
Sylvia M. C. Todescan, Robert J. Schroth, Heather Dean, Brandy Wicklow, Edgard Michel-Crosato, Elizabeth Sellers
doi : 10.1002/JPER.21-0226
The aim of the present study was to determine the prevalence of periodontitis in children and adolescents with type 2 diabetes, and if poor glycemic control is associated with increasing prevalence of the disease.
Flap versus flapless alveolar ridge preservation: A clinical and histological single-blinded, randomized controlled trial
Trever L. Siu, Himabindu Dukka, Muhammad H. A. Saleh, Mustafa Tattan, Ziad Dib, Andrea Ravidà, Henry Greenwell, Hom-Lay Wang, Mauricio G. Araujo
doi : 10.1002/JPER.22-0213
The aim of this randomized clinical trial was to compare a flapless technique of alveolar ridge preservation (ARP) to a flap technique to determine if preserving the periosteal blood supply would limit loss of crestal ridge width and height.
Epidemiological and sociodemographic transitions of severe periodontitis incidence, prevalence, and disability-adjusted life years for 21 world regions and globally from 1990 to 2019: An age-period-cohort analysis
Yiran Cui, Gang Tian, Ri Li, Yan Shi, Tong Zhou, Yan Yan
doi : 10.1002/JPER.22-0241
Severe periodontitis is one of the most prevalent diseases and a global public health problem due to its high incidence and prevalence. However, there are few studies on the burden of periodontitis in different regions of the world.
Serum antibodies to periodontal pathogens are related to allergic symptoms
Mi Du, Shulan Xu, Bingjiang Qiu, Shixian Hu, Geerten-Has E. Tjakkes, An Li, Shaohua Ge
doi : 10.1002/JPER.22-0346
The association between periodontitis and allergic symptoms has been investigated. However, the difference in immune signatures between them remains poorly understood. This cross-sectional study assessed the relationship between serum immunoglobulin G (IgG) antibodies to periodontal pathogens and allergic symptoms in a nationwide population cohort.
Probiotic consumption can modify the resilience of periodontal tissues in rats under experimental periodontitis
Luiz Fernando Ferreira de Oliveira, Pedro Henrique Felix Silva, Sergio Luiz Salvador, Edilson Ervolino, Renato Casarin, Luciene Figueiredo, Milla Tavares Ricoldi, Sérgio LuÃs Scombatti de Souza, Flavia Furlaneto, Michel Reis Messora
doi : 10.1002/JPER.21-0555
This study evaluated the effects of systemic administration of Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) on experimental periodontitis (EP) in rats.
Soft tissue augmentation with a volume-stable collagen matrix or an autogenous connective tissue graft at implant sites: Five-year results of a randomized controlled trial post implant loading
Daniel S. Thoma, Thomas J. W. Gasser, Christoph H. F. Hämmerle, Franz J. Strauss, Ronald E. Jung
doi : 10.1002/JPER.22-0226
Interventions to augment the mucosal thickness around dental implants are indicated to optimize esthetics and maintain peri-implant health. However, there is a lack of clinical data on the long-term performance of soft tissue substitutes, such as volume-stable collagen matrix (VCMX), compared to autogenous grafts, such as subepithelial connective tissue grafts (SCTGs). This randomized controlled trial aimed to assess 5-year data on clinical and radiographic outcomes at implant sites previously augmented with VCMX or SCTG.
Abaloparatide outperforms teriparatide in protecting against alveolar bone loss in experimental periodontitis
Yuan Li, Yuran Qian, Hui Qiao, Weiyi Pan, Liang Xie, Yu Li
doi : 10.1002/JPER.22-0211
The aim of this study was to compare the effects of two osteoanabolic drugs, abaloparatide (ABL) and teriparatide (TPTD), on protecting alveolar bone in experimental periodontitis.
The causal effect of life course adiposity on periodontitis: A Mendelian randomization study
Wenjing Li, Ying He, Qiwen Zheng, Xuliang Deng
doi : 10.1002/JPER.21-0632
To establish whether life course adiposity, including birth weight (BW), childhood and adulthood body mass index (BMI), waist–hip ratio (WHR), and body fat percentage (BF%), has a causal influence on periodontitis.
Hertwig's epithelial root sheath cells show potential for periodontal complex regeneration
Fei Bi, Huilin Tang, Zhijun Zhang, Yun Lyu, Fangjun Huo, Guoqing Chen, Weihua Guo
doi : 10.1002/JPER.22-0072
Although researchers have been exploring therapeutic strategies of treating serious periodontal tissue loss, including the application of stem cells, tissue regeneration of the periodontal complex involving cementum, periodontium, and alveolar bone has hardly been achieved.
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling
Xue Yuan, Vedanshi Amin, Tianli Zhu, Mizuho Kittaka, Yasuyoshi Ueki, Teresita M. Bellido, Hakan Turkkahraman
doi : 10.1002/JPER.22-0192
Type 1 diabetes mellitus (T1DM) and periodontitis have long been thought to be biologically connected. Indeed, T1DM is a risk factor for periodontal disease. With the population of diabetic individuals growing, it is more important than ever to understand the negative consequences of diabetes on the periodontium and the mechanisms.
M2 macrophages with inflammation tropism facilitate cementoblast mineralization
Xin Huang, Xiaoxuan Wang, Li Ma, Huiyi Wang, Yan Peng, Heyu Liu, Junhong Xiao, Zhengguo Cao
doi : 10.1002/JPER.22-0048
Cementum regeneration was regarded as the critical goal for periodontal regeneration, and M2 macrophage-based therapy was expected to be a promising strategy. However, little is known about the effects of M2 macrophages on cementoblast mineralization and tropism, especially under inflammation. Here we investigated for the first time the crosstalk between M2 macrophages and Porphyromonas gingivalis (Pg)-stimulated cementoblasts.
