Circulation




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Cardiometabolic HFpEF: NASH of the Heart.

Capone, Federico MD; Vettor, Roberto MD; Schiattarella, Gabriele G. MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.062874

Volume 147(6) pgs. 451-518,e73-e75 February 07, 2023

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Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Results of the ECMO-CS Randomized Clinical Trial.

Ostadal, Petr MD, PhD; Rokyta, Richard MD, PhD; Karasek, Jiri MD, PhD; Kruger, Andreas MD, PhD; Vondrakova, Dagmar MD, PhD; Janotka, Marek MD; Naar, Jan MD, PhD; Smalcova, Jana MD; Hubatova, Marketa MSc; Hromadka, Milan MD, PhD; Volovar, Stefan MD; Seyfrydova, Miroslava MD; Jarkovsky, Jiri PhD; Svoboda, Michal MSc; Linhart, Ales MD, PhD; Belohlavek, Jan MD, PhD; for the ECMO-CS Investigators

doi : 10.1161/CIRCULATIONAHA.122.062949

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly being used for circulatory support in patients with cardiogenic shock, although the evidence supporting its use in this context remains insufficient.

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Extracorporeal Membrane Oxygenation for Cardiogenic Shock: When to Open the Parachute?.

Henry, Timothy D. MD; Yannopoulos, Demetri MD; van Diepen, Sean MD, MSc

doi : 10.1161/CIRCULATIONAHA.122.063190

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Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients: PROSPECT II.

Gyldenkerne, Christine MD; Maeng, Michael MD, PhD; Kjoller-Hansen, Lars DMSc; Maehara, Akiko MD; Zhou, Zhipeng MA; Ben-Yehuda, Ori MD; Erik Botker, Hans MD, PhD, DMSc; Engstrom, Thomas MD, PhD; Matsumura, Mitsuaki BS; Mintz, Gary S. MD; Frobert, Ole MD, PhD; Persson, Jonas MD, PhD; Wiseth, Rune MD, PhD; Larsen, Alf I. MD, PhD; Jensen, Lisette O. MD, PhD; Nordrehaug, Jan E. MD, PhD; Bleie, Oyvind MD, PhD; Omerovic, Elmir MD, PhD; Held, Claes MD, PhD; James, Stefan K. MD, PhD; Ali, Ziad A. MD, DPhil; Rosen, Hans C. BSc; Stone, Gregg W. MD; Erlinge, David MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.061983

Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content.

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The Effect of Lymphangiogenesis in Transplant Arteriosclerosis.

Chen, Kai MB; Mou, Rong MB; Zhu, Pengwei MB; Xu, Xiaodong MB; Wang, Han MSc; Jiang, Liujun PhD; Hu, Yanhua MD; Hu, Xiaosheng MD; Ma, Liang MD; Xiao, Qingzhong MD, PhD; Xu, Qingbo MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.060799

Transplant arteriosclerosis is a major complication in long-term survivors of heart transplantation. Increased lymph flow from donor heart to host lymph nodes has been reported to play a role in transplant arteriosclerosis, but how lymphangiogenesis affects this process is unknown.

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Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction.

Masurkar, Nihar PhD ,*; Bouvet, Marion PhD ,*; Logeart, Damien MD, PhD; Jouve, Charlene MSc; Drame, Fatou MSc; Claude, Olivier PhD; Roux, Maguelonne PhD; Delacroix, Clement PhD; Bergerot, Damien MSc; Mercadier, Jean-Jacques MD, PhD; Sirol, Marc MD, PhD; Gellen, Barnabas MD, PhD; Livrozet, Marine MD, PhD; Fayol, Antoine MD; Robidel, Estelle MSc; Tregouet, David-Alexandre PhD; Marazzi, Giovanna MD, PhD; Sassoon, David PhD; Valente, Mariana PhD; Hulot, Jean-Sebastien MD, PhD

doi : 10.1161/CIRCULATIONAHA.121.056272

Myocardial infarction (MI) induces a repair response that ultimately generates a stable fibrotic scar. Although the scar prevents cardiac rupture, an excessive profibrotic response impairs optimal recovery by promoting the development of noncontractile fibrotic areas.

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No Benefit Seen for Nighttime Dosing Over Morning Dosing for Antihypertensive Medications.

Kuehn, Bridget M.

doi : 10.1161/CIRCULATIONAHA.122.063314

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Stepwise Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction.

Shen, Mengcheng PhD ,,,*; Liu, Chun PhD ,,,*; Zhao, Shane Rui PhD; Manhas, Amit PhD; Sundaram, Laksshman PhD; Ameen, Mohamed PhD; Wu, Joseph C. MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.061770

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Letter by Sawami et al Regarding Article, "Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF)".

Sawami, Kosuke MD; Tanaka, Atsushi MD, PhD; Node, Koichi MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.062333

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Response by Schulze et al to Letter Regarding Article, "Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF)".

Schulze, P. Christian MD, PhD; Bogoviku, Jurgen MD; Westphal, Julian MD; Aftanski, Pawel MD; Haertel, Franz MD; Grund, Sissy MS; Haehling, Stephan von MD, PhD; Schumacher, Ulrike PhD; Mobius-Winkler, Sven MD, PhD; Busch, Martin MD

doi : 10.1161/CIRCULATIONAHA.122.062688

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