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Brain stimulation treatment for bipolar disorder
Julian Mutz
doi : 10.1111/bdi.13283
Bipolar disorders are clinically complex, chronic and recurrent disorders. Few treatment options are effective across hypomanic, manic, depressive and mixed states and as continuation or maintenance treatment after initial symptom remission.
Genetic liability to bipolar disorder and body mass index: A bidirectional two-sample Mendelian randomization study
Lars Meinertz Byg, Maria Speed, Doug Speed, Søren Dinesen Østergaard
doi : 10.1111/bdi.13267
Bipolar disorder is associated with increased body mass index (BMI), but it remains undetermined if this association is causal and, if so, in which direction it goes. Here, we sought to answer these questions using bidirectional two-sample Mendelian randomization, a method from genetic epidemiology that uses data from genome-wide association studies (GWAS) to examine whether a risk factor is causal for an outcome
Insulin resistance disrupts white matter microstructure and amplitude of functional spontaneous activity in bipolar disorder
Elena Mazza, Federico Calesella, Marco Paolini, Camilla di Pasquasio, Sara Poletti, Cristina Lorenzi, Andrea Falini, Raffaella Zanardi, Cristina Colombo, Francesco Benedetti
doi : 10.1111/bdi.13270
Bipolar disorder (BD) is linked to several structural and functional brain alterations. In addition, BD patients have a three-fold increased risk of developing insulin resistance, which is associated with neural changes and poorer BD outcomes. Therefore, we investigated the effects of insulin and two derived measures (insulin resistance and sensitivity) on white matter (WM) microstructure, resting-state (rs) functional connectivity (FC), and fractional amplitude of low-frequency fluctuation (fALFF).
Bipolar I and bipolar II subtypes in older age: Results from the Global Aging and Geriatric Experiments in Bipolar Disorder (GAGE-BD) project
Alexandra J. M. Beunders, Federica Klaus, Almar A. L. Kok, Sigfried N. T. M. Schouws, Ralph W. Kupka, Hilary P. Blumberg, Farren Briggs, Lisa T. Eyler, Brent P. Forester, Orestes V. Forlenza, Ariel Gildengers, Esther Jimenez, Benoit H. Mulsant, Regan E. Patrick, Soham Rej, Martha Sajatovic, Kaylee Sarna, Ashley Sutherland, Joy Yala, Eduard Vieta, Luca M. Villa, Nicole C. M. Korten, Annemieke Dols
doi : 10.1111/bdi.13271
The distinction between bipolar I disorder (BD-I) and bipolar II disorder (BD-II) has been a topic of long-lasting debate. This study examined differences between BD-I and BD-II in a large, global sample of OABD, focusing on general functioning, cognition and somatic burden as these domains are often affected in OABD.
Lithium in breast milk transiently affects the renal electrolytic balance of infants
Irfan Ahmed, Muhammad Shehzad Khan, Victor Ma, Hina Magsi, Renardi Gunawan, Abdul-Mojeed Olabisi Ilyas, Najeeb ur Rehman Lashari, Naveed Wassan, Santosh Paidi, Zulfiqar Ali, Alan W. L. Law, Yanpeng Zhang, William C. Cho, Martin Alda, Veerle Bergink, Ishan Barman, Condon Lau
doi : 10.1111/bdi.13275
The use of lithium during breast-feeding has not been comprehensively investigated in humans due to concerns about lithium toxicity.
Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial
Seena George, Rituparna Maiti, Biswa Ranjan Mishra, Monalisa Jena, Debadatta Mohapatra
doi : 10.1111/bdi.13276
Lithium-induced natriuresis may lead to lithium retention and fluctuation of lithium levels during maintenance therapy. Therefore, the present study was conducted to evaluate the effect of add-on sodium chloride on serum lithium levels in bipolar disorder.
Staging the bipolar disorders: Are early stages too early a stage for intervention?
Anne Duffy, Charles Keown-Stoneman
doi : 10.1111/bdi.13281
Early clinical staging: Why does it matter, and what do we know?
Danella M. Hafeman, Tina R. Goldstein, Boris Birmaher
doi : 10.1111/bdi.13290
Progressive cognitive impairment in bipolar disorder: An assumption that holds true no matter what
Cecilia Samamé
doi : 10.1111/bdi.13289
Isoniazid-induced mania and the history of antidepressant drugs: Case report and literature review
Ana Isabel Carvalho Boavista Samouco, Sónia Pimenta Alves
doi : 10.1111/bdi.13272
First manic episode during COVID-19 infection after IVF treatment: A case report
Merve Akkus, Onur Gökçen, Erdal Pirincci
doi : 10.1111/bdi.13264
