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Clinical Images: Severe interstitial lung disease in Sjögren disease � What happens in the lungs? Inflammation or fibrosis?
Tobias Hoffmann, Nikolaus Gassler, Ulf Teichgräber, Tim Sandhaus, Peter Oelzner, Gunter Wolf, Alexander Pfeil
doi : 10.1002/acr2.11516
Selective Inhibition of the MK2 Pathway: Data From a Phase IIa Randomized Clinical Trial in Rheumatoid Arthritis
David Gordon, Alan Kivitz, Atul Singhal, David Burt, Madison C. Bangs, Emma E. Huff, Heidi Rath Hope, Joseph B. Monahan
doi : 10.1002/acr2.11517
The study objective was to evaluate the safety, tolerability, pharmacodynamics, and preliminary efficacy of ATI-450 with methotrexate in patients with rheumatoid arthritis (RA).
Subclinical Systemic Sclerosis Primary Heart Involvement by Cardiovascular Magnetic Resonance Shows No Significant Interval Change
Raluca B. Dumitru, Lesley-Anne Bissell, Bara Erhayiem, Graham Fent, Ananth Kidambi, Giuseppina Abignano, John P. Greenwood, John Biglands, Francesco Del Galdo, Sven Plein, Maya H. Buch
doi : 10.1002/acr2.11515
Subclinical systemic sclerosis (SSc) primary heart involvement is commonly described. Whether these findings progress over time is not clear. The study aimed to investigate cardiovascular magnetic resonance (CMR) interval change of subclinical SSc primary heart involvement.
Giant Cell Arteritis: A Systematic Review and Meta-Analysis of Test Accuracy and Benefits and Harms of Common Treatments
doi : 10.1002/acr2.11519
Vaccination Rates, Perceptions, and Information Sources Used by People With Inflammatory Arthritis
Andrea Lyon, Alannah Quinlivan, Susan Lester, Claire Barrett, Samuel L. Whittle, Debra Rowett, Rachel Black, Premarani Sinnathurai, Lyn March, Rachelle Buchbinder, Catherine L. Hill
doi : 10.1002/acr2.11525
To determine vaccination rates, perceptions, and information sources in people with inflammatory arthritis.
Transcriptome Profiling of Immune Cell Types in Peripheral Blood Reveals Common and Specific Pathways Involved in the Pathogenesis of Myositis-Specific Antibody-Positive Inflammatory Myopathies
Yusuke Sugimori, Yukiko Iwasaki, Yusuke Takeshima, Mai Okubo, Satomi Kobayashi, Hiroaki Hatano, Saeko Yamada, Masahiro Nakano, Ryochi Yoshida, Mineto Ota, Yumi Tsuchida, Yasuo Nagafuchi, Kenichi Shimane, Ken Yoshida, Daitaro Kurosaka, Shuji Sumitomo, Hirofumi Shoda, Kazuhiko Yamamoto, Tomohisa Okamura, Keishi Fujio
doi : 10.1002/acr2.11521
Idiopathic inflammatory myopathies (IIM) demonstrate characteristic clinical phenotypes depending on the myositis-specific antibody (MSAs) present. We aimed to identify common or MSA-specific immunological pathways in different immune cell types from peripheral blood by transcriptome analysis.
