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NEW ARTIFICIAL INTELLIGENCE ANALYSIS FOR PREDICTION OF LONG-TERM VISUAL IMPROVEMENT AFTER EPIRETINAL MEMBRANE SURGERY.

Crincoli, Emanuele MD *,+; Savastano, Maria Cristina MD, PhD *,+; Savastano, Alfonso MD *,+; Caporossi, Tomaso MD, PhD *,+; Bacherini, Daniela MD, PhD ++; Miere, Alexandra MD, PhD [S]; Gambini, Gloria MD *,+; De Vico, Umberto MD *,+; Baldascino, Antonio MD *,+; Minnella, Angelo Maria MD *,+; Scupola, Andrea MD *,+; DAmico, Guglielmo MD *,+; Molle, Fernando MD *,+; Bernardinelli, Patrizio MD *,+; De Filippis, Alessandro MD *,+; Kilian, Raphael MD [P]; Rizzo, Clara MD **; Ripa, Matteo MD +; Ferrara, Silvia MD *,+; Scampoli, Alessandra MD *,+; Brando, Davide MD *,+; Molle, Andrea MD *,+; Souied, Eric H. MD, PhD [S]; Rizzo, Stanislao MD *,+,++

doi : 10.1097/IAE.0000000000003646

Volume 43(2) pgs. 173-369,e6-e12 February 2023

To predict improvement of best-corrected visual acuity (BCVA) 1 year after pars plana vitrectomy for epiretinal membrane (ERM) using artificial intelligence methods on optical coherence tomography B-scan images.

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EPIRETINAL MEMBRANE WITH FOVEAL HERNIATION: Visual and Surgical Outcomes.

Shah, Saumya M. MD *; Eliott, Dean MD +; Cox, Jacob T. MD, MPhil +; Yonekawa, Yoshihiro MD ++; Mahmoudzadeh, Raziyeh MD ++; Peck, Travis J. MD ++; Regillo, Carl D. MD ++; Ho, Allen C. MD ++; Oellers, Patrick MD [S]; Choudhury, Mahin BS [S]; Arboleda, Nathan BS [S]; Gentile, Ronald C. MD [P],**; Sun, Vincent MD [P]; Iezzi, Raymond MD, MS *

doi : 10.1097/IAE.0000000000003669

Foveal herniation occurs when neuroretinal tissue protrudes through and above the level of an epiretinal membrane. This study describes the visual symptoms and spectral domain optical coherence tomography findings associated with foveal herniation and evaluates the postoperative visual, anatomical, and surgical outcomes.

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PEELED INTERNAL LIMITING MEMBRANE REPOSITION FOR IDIOPATHIC MACULAR HOLES: A Pilot Randomized Controlled Trial.

Tian, Tian MD, PhD *; Tan, Hongsheng PhD +; Zhu, Xiuyu MD *; Zhang, Xiang MD *; Zhao, Peiquan MD, PhD *

doi : 10.1097/IAE.0000000000003645

To compare the functional and anatomical outcomes of peeled internal limiting membrane reposition and traditional internal limiting membrane peeling for the treatment of idiopathic macular hole.

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EXCESSIVE GLIOSIS AFTER VITRECTOMY FOR THE HIGHLY MYOPIC MACULAR HOLE: A Spectral Domain Optical Coherence Tomography Study.

Ye, Xin MD, PhD *; Wang, Jun MD *; Qiu, Wangli MD *; Chen, Yiqi MD, PhD +; Shen, Lijun MD, PhD *,+

doi : 10.1097/IAE.0000000000003657

To investigate different modes of foveal regeneration after the closure of idiopathic macular hole (IMH) or highly myopic macular hole (HMMH) by vitrectomy with internal limiting membranes peeling or flap techniques.

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VOLUMETRIC ANALYSIS OF LAMELLAR MACULAR HOLE: An Optical Coherence Tomography Study.

Tasl[latin dotless i]p[latin dotless i]nar Uzel, Ayse Guzin MD *; Gelisken, Faik MD +; Kuhlewein, Laura MD +; Neubauer, Jonas MD +

doi : 10.1097/IAE.0000000000003665

To investigate the cavity of lamellar macular holes (LMH-CV) by using volumetric analysis of optical coherence tomography images. Methods: Single-center, retrospective, observational case series.

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FULL-THICKNESS MACULAR HOLE WITH PERSISTENT BROAD VITREOMACULAR ATTACHMENT: Clinical Characteristics and Surgical Outcomes.

Uemura, Akinori MD *; Yamakiri, Keita MD *; Santo, Kyoko MD *; Hamada, Takuto MD *; Miyake, Shoki MD *; Sakamoto, Taiji MD +

doi : 10.1097/IAE.0000000000003671

To describe the characteristics and surgical outcomes of full-thickness macular holes (FTMHs) with persistent broad vitreomacular attachment. Methods: This was a retrospective, observational case series.

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DIFFERENCES IN ANATOMICAL AND VISUAL OUTCOMES AMONG THREE INTERNAL LIMITING MEMBRANE TECHNIQUES TREATING EXTRA-LARGE IDIOPATHIC MACULAR HOLES.

Liu, Lingzi MD *,+; Yu, Yanping MD *,+; Yang, Xiaohan MD *,+; Wang, Zengyi MD *,+; Qi, Biying MD *,+; Zhang, Ke MD *,+; Wu, Xijin MD *,+; Wang, Xinbo MD *,+; Liu, Wu MD, PhD *,+

doi : 10.1097/IAE.0000000000003672

To compare the anatomical and visual outcomes of extra-large idiopathic macular holes treated with internal limiting membrane peeling and two inverted internal limiting membrane flap techniques, namely insertion and cover technique.

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PRENATAL MATERNAL CHARACTERISTICS ASSOCIATED WITH RETINOPATHY OF PREMATURITY.

Strawbridge, Jason C. BA *; Chu, Alison MD +; Dammann, Olaf MD, SM, PhD ++,[S],[P]; Hanson, Justin BA *; Janzen, Carla MD, PhD **; Tsui, Irena MD ++

doi : 10.1097/IAE.0000000000003674

Determine whether prenatal maternal characteristics such as sociodemographic characteristics, comorbidities, or pregnancy complications affect retinopathy of prematurity (ROP) development.

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27-GAUGE PARS PLANA/PLICATA VITRECTOMY FOR PEDIATRIC VITREORETINAL SURGERY.

Ung, Cindy MD *; Yonekawa, Yoshihiro MD +; Chung, Mina M. MD ++; Berrocal, Audina M. MD [S]; Kusaka, Shunji MD [P]; Oshima, Yusuke MD **; Chan, R. V. Paul MD ++; Inoue, Makoto MD ++++; Read, Sarah P. MD, PhD [S][S]; Kuriyan, Ajay E. MD +; Todorich, Bozho MD, PhD [P][P]; Thanos, Aristomenis MD ***; Thomas, Benjamin J. MD +++; Wolfe, Jeremy D. MD ++++++; Hassan, Tarek S. MD ++++++; Capone, Antonio Jr MD ++++++

doi : 10.1097/IAE.0000000000003662

To report on the feasibility of 27-gauge (G) vitrectomy for pediatric patients. Methods: This study is an international, multicenter, retrospective, interventional case series.

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THE REPORTING QUALITY OF NONINFERIORITY TRIALS USING INTRAVITREAL VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITORS.

Jia, Huixun PhD *; Li, Tong MD *; Wan, Hongli PhD +; Wu, Zhenyu PhD +; Sun, Xiaodong MD, PhD *

doi : 10.1097/IAE.0000000000003649

Noninferiority trials (NIFTs) are widely used to study intravitreal vascular endothelial growth factor inhibitors for the treatment of ocular diseases. Thus, this trial design deserves greater attention.

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INCIDENCE OF NEW DIABETIC MACULAR EDEMA IN FELLOW EYES OF PATIENTS IN THE VISTA AND VIVID STUDIES.

Dhoot, Dilsher S. MD *; Moini, Hadi PhD +; Reed, Kimberly OD +; Silva, Fabiana Q. MD +; Berliner, Alyson MD, PhD +; Du, Weiming MS +; Sharma, Sumit MD ++

doi : 10.1097/IAE.0000000000003658

To characterize diabetic macular edema (DME) incidence in fellow eyes of patients treated for DME in the study eye. Methods: This post hoc analysis of VISTA/VIVID data evaluated fellow eyes without DME at baseline through Week 100.

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TRANSPLANTATION OF SUBRETINAL STEM CELL-DERIVED RETINAL PIGMENT EPITHELIUM FOR STARGARDT DISEASE: A Phase I Clinical Trial.

Brant Fernandes, Rodrigo A. MD, PHD *; Lojudice, Fernando H. PHD +; Zago Ribeiro, Lucas MD *; Santos da Cruz, Natasha Ferreira MD *; Polizelli, Murilo Ubukata MD *; Cristovam, Priscila C. PHD *; Innocenti, Francesco *,+; Morimoto, Lisangela *; Magalhaes, Octaviano Jr MD, PHD *; Ferraz Sallum, Juliana Maria MD, PhD *; Penha, Fernando Marcondes MD, PHD *; Sogayar, Mari C. PhD +; Belfort, Rubens Jr MD, PHD *; Maia, Mauricio MD, PHD *

doi : 10.1097/IAE.0000000000003655

To assess the safety of injecting human embryonic stem cell retinal pigment epithelial cell dose to treat Stargardt disease. Methods: In this prospective, Phase I clinical trial, human embryonic stem cell retinal pigment epithelial cells in suspension were injected into the subretinal space in eyes with the worse best-corrected visual acuity (BCVA).

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RISK FACTORS OF VISION LOSS AND MULTIPLE RECURRENCES IN MYOPIC MACULAR NEOVASCULARIZATION.

Cicinelli, Maria Vittoria MD *,+; L T De Felice, Elisabetta MD *; La Franca, Lamberto MD *,+; Rabiolo, Alessandro MD +; Marchese, Alessandro MD *,+; Battaglia Parodi, Maurizio MD *,+; Introini, Ugo MD +; Bandello, Francesco MD *,+

doi : 10.1097/IAE.0000000000003673

To investigate the factors associated with maximum visual improvement (peak vision) gain and the risk factors of peak vision loss and multiple recurrences in myopic macular neovascularization undergoing antivascular endothelial growth factor therapy.

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CHORIOCAPILLARIS STRUCTURE IN THE FELLOW EYES OF PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: An OCT Angiography Image Averaging Study.

Kamei, Takuro MD; Ooto, Sotaro MD; Uji, Akihito MD; Ichioka, Ai MD; Tsujikawa, Akitaka MD

doi : 10.1097/IAE.0000000000003660

Histological choriocapillaris abnormalities have been reported in age-related macular degeneration (AMD). Averaging multiple en face optical coherence tomography angiography improves the quality of imaging of the choriocapillaris.

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FIVE-YEAR INCIDENCE OF FELLOW EYE NEOVASCULAR INVOLVEMENT IN AGE-RELATED MACULAR DEGENERATION AND POLYPOIDAL CHOROIDAL VASCULOPATHY IN AN ASIAN POPULATION.

Teo, Kelvin Yi Chong PhD *,+; Vyas, Chinmayi MS(Ophth) *; Sun, Christopher MMed(Ophth) *; Cheong, Kai Xiong MPH *; Chakravarthy, Usha PhD ++

doi : 10.1097/IAE.0000000000003666

To assess 5-year cumulative incidence and risk factors of fellow eye involvement in Asian neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy. Methods: In a prospective cohort study of Asian nAMD and polypoidal choroidal vasculopathy, the fellow eyes were evaluated for exudation. The 5-year incidence of exudation was compared between nAMD and polypoidal choroidal vasculopathy.

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PATTERN AND CHARACTERISTICS OF DRUSEN SUBTYPES IN CHINESE AND INDIAN POPULATIONS IN SINGAPORE.

Takahashi, Kengo MD, PhD *,+; Song, Youngseok MD, PhD *,+; Cheong, Kai Xiong MBBS *; Fenner, Beau J. MD, PhD *,++; Teo, Kelvin Yi Chong MBBS, MMed(Ophth) *,++; Chee, Miao Li BSc *; Li, Hengtong MS *; Tham, Yih-Chung PhD *,+; Cheung, Chui Ming Gemmy MBBS, FRCOphth *,++; Cheng, Ching-Yu MD, PhD *,++,[S]; Wong, Tien Yin MBBS, PhD *,++,[S]; Yanagi, Yasuo MD, PhD *; Tan, Anna C. S. MBBS, MMed(Ophth) *,++

doi : 10.1097/IAE.0000000000003651

To report the pattern and characteristics of drusen subtypes in Asian populations and the association with choroidal thickness. Methods: This is the cross-sectional analysis of the population-based cohort study.

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NONPERFORATING INTRASCLERAL STABBING FOR SUTURELESS 23G SCLEROTOMY CLOSURE.

Yalcinbayir, Ozgur MD *,+; Ucan Gunduz, Gamze MD *; Nizam, Sema *; Yildiz, Meral MD *

doi : 10.1097/IAE.0000000000003648

The need for suturing leaking sclerotomies have not been eliminated completely in transconjunctival sutureless vitrectomy (TSV). This study aims to describe a novel technique for 23-gauge (G) sclerotomy closure in TSV surgery and discuss its effectiveness.

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SPONTANEOUS REATTACHMENT OF RHEGMATOGENOUS RETINAL DETACHMENT: Observations of the Vitreoretinal Interface.

Son, Ki Young MD; Hwang, Sungsoon MD; Kang, Se Woong MD, PhD; Kim, Sang Jin MD, PhD; Choi, Jae Hwan MD; Choi, Kyung Jun MD; Park, Hansol MD

doi : 10.1097/IAE.0000000000003650

To describe the clinical characteristics and posterior vitreous findings of spontaneous reattachment of rhegmatogenous retinal detachment (SRRRD).

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LONG-TERM CHANGES IN VISUAL FUNCTION AND EN FACE OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN FOVEA-OFF RETINAL DETACHMENT: A 2-Year Prospective Study.

Thomseth, Vilde M. MD *,+; Lindtjorn, Birger MD *,++; Ushakova, Anastasia PhD [S]; Forsaa, Vegard A. MD, PhD *,+

doi : 10.1097/IAE.0000000000003670

To investigate the long-term changes in visual function and outer retinal abnormalities on en face optical coherence tomography after fovea-off rhegmatogenous retinal detachment and to assess associations between functional outcomes and outer retinal abnormalities.

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COMBINED HAMARTOMA OF THE RETINA AND RETINAL PIGMENT EPITHELIUM AT PEDIATRIC AGE: Surgical Versus Conservative Approach.

Ozdek, Sengul MD, FEBO, FASRS *; Ucgul, Ahmet Yucel MD, FICO, FEBO *,+; Hartnett, M. Elizabeth MD, FACS, FARVO ++; Akdogan, Muberra MD [S]; Sen, Parveen MS [P]; Bhende, Muna MS [P]; Besirli, Cagri Giray MD; PhD **; Karacorlu, Murat MD; MSc, FEBO ++; Dedania, Vaidehi MD ++++; Parolini, Barbara MD [S][S]; Mittal, Sangeet MD [P][P]; Banker, Alay MD ***; El Rayes, Ehab MD, PhD +++; Tawfik, Mohamed MD, FRCSed ++++++; Wu, Wei-Chi MD, PhD [S][S][S]; Attiku, Yamini MD [P]; Hansen, Eric MD ++; Portney, David BS **; Sarvaiya, Chintan MD ***; Sahin, Ozlem MD [P][P][P]; Ozdemir, Huseyin Baran MD, FICO, FEBO *; Gurelik, Gokhan MD *

doi : 10.1097/IAE.0000000000003652

To report outcomes of pediatric patients with combined hamartoma of the retina and the retina pigment epithelium followed up conservatively or after pars plana vitrectomy.

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SYMPTOMATIC EARLY-ONSET X-LINKED RETINOSCHISIS: Clinical Presentation and Outcomes.

Piquin, Gwendoline MD *; Abdelmassih, Youssef MD *; Martin, Gilles MD *; Edelson, Catherine MD *; Metge, Florence MD *; Caputo, Georges MD *; Chapron, Thibaut MD *,+

doi : 10.1097/IAE.0000000000003667

To describe clinical characteristics and outcomes of children with early-onset X-linked retinoschisis. Methods: In this retrospective consecutive case series, we included children diagnosed with symptomatic X-linked retinoschisis younger than 2 years.

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Controlling a Digital Cursor With a Sterile Gyroscopic Mouse in Digitally Assisted Vitreoretinal Surgery.

Bausili, Montserrat M. FEBO, PhD; Gilhotra, Jagjit S. FRANZCO, MMed (Clin Epi); Durkin, Shane R. MBBS(Hons), FRANZCO; Chan, Weng Onn FRANZCO, MPhil

doi : 10.1097/IAE.0000000000002801

To describe our experience using the gyroscopic mouse in digitally assisted vitreoretinal surgery. Methods: We used a commercially available gyroscopic mouse to control the on-screen cursor of the NGENUITY System for digitally assisted vitreoretinal surgery.

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Intraoperative Three-Dimensional Fluorescein Angiography-Guided Pars Plana Vitrectomy for the Treatment of Proliferative Diabetic Retinopathy: The Maximized Utility of the Digital Assisted Vitrectomy.

Imai, Hisanori MD, PhD; Tetsumoto, Akira MD; Inoue, Saki MD; Takano, Fumio MD; Yamada, Hiroko MD; Hayashida, Mayuka MD; Otsuka, Keiko MD, PhD; Miki, Akiko MD, PhD; Kusuhara, Sentaro MD, PhD; Nakamura, Makoto MD, PhD

doi : 10.1097/IAE.0000000000002805

To show the usefulness of the intraoperative three-dimensional fluorescein angiography (3D-FA)-guided pars plana vitrectomy. Methods: The NGENUITY 3D visualization system was used for the digital assisted vitrectomy.

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Scleral Buckling Using Chandelier and Releasable Suture: A Useful Surgical Variant.

Savastano, Alfonso MD *; Weinberg, Tamir MD +; Faraldi, Francesco MD ++; Caporossi, Tomaso MD [S]; Rizzo, Stanislao MD *,[P],**

doi : 10.1097/IAE.0000000000002823

To describe a surgical variant for scleral buckling technique using a chandelier and scleral releasable suture. Methods: We collected retrospectively 20 eyes of 20 patients who underwent to scleral buckling for retinal detachment.

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Diagnostic and Therapeutic Challenges.

Ding, Xiaohu PhD; Yuan, Zhaohui PhD; Lin, Xiaofeng PhD; Brodie, Frank L.

doi : 10.1097/IAE.0000000000003511

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Multimodal Imaging and Microperimetry of Retinal Pigment Epithelium Tear-Associated Resurfacing Tissue.

Ramtohul, Prithvi MD *; Cabral, Diogo MD *; Freund, K. Bailey MD *,+

doi : 10.1097/IAE.0000000000003668

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Correspondence.

Patton, Niall MD, FRCOphth *; Jalil, Assad MB, BS, FRCOphth *; Stavrakis, Panagiotis MD, PhD, FEBO +; Dhawahir-Scala, Felipe FRCSEd *

doi : 10.1097/IAE.0000000000003653

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Reply.

El Rayes, Ehab N. MD, PhD, FASRS *,+; Habib, Ahmed M. MD, FRCS ++; Soliman, Ashraf H. MD, FRCS ++; Ibrahim, Ola M. MD, FRCS ++; El Sawwah, Karim M. H. MSC, OPHTH *

doi : 10.1097/IAE.0000000000003654

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Correspondence.

Chen, Nelson BHSc *,+; Hsiao, Meng-Chang PhD ++; Wang, Nan-Kai MD, PhD +

doi : 10.1097/IAE.0000000000003664

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Reply.

Chen, Ta-Ching MD, PhD *,+; Chen, Pei-Lung MD, PhD ++,[S],[P]; Chen, Yi-Chieh MS *; Yang, Chang-Hao MD, PhD *,**; Yang, Chung-May MD *,**

doi : 10.1097/IAE.0000000000003663

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