Clinical and Translational Gastroenterology




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Colorectal Cancer After Screening Colonoscopy: 10-Year Incidence by Site and Detection Rate at First Repeat Colonoscopy.

Schwarz, Sarina MSc 1; Hornschuch, Michel MSc 1; Pox, Christian MD 2; Haug, Ulrike PhD 1,3

doi : 10.14309/ctg.0000000000000535

Volume 14(1) pgs. e00535-e00557 January 2023

We aimed to describe cumulative colorectal cancer (CRC) incidence after screening colonoscopy stratified by tumor location, age, and sex as well as CRC detection rate at first repeat colonoscopy.

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Quantitative Radiomic Features From Computed Tomography Can Predict Pancreatic Cancer up to 36 Months Before Diagnosis.

Chen, Wansu PhD 1; Zhou, Yichen MS 1; Asadpour, Vahid PhD 1; Parker, Rex A. MD 2; Puttock, Eric J. PhD 1; Lustigova, Eva MPH 1; Wu, Bechien U. MD, MPH 3

doi : 10.14309/ctg.0000000000000548

Pancreatic cancer is the third leading cause of cancer deaths among men and women in the United States. We aimed to detect early changes on computed tomography (CT) images associated with pancreatic ductal adenocarcinoma (PDAC) based on quantitative imaging features (QIFs) for patients with and without chronic pancreatitis (CP).

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Efficacy of a Digital Personalized Elimination Diet for the Self-Management of Irritable Bowel Syndrome and Comorbid Irritable Bowel Syndrome and Inflammatory Bowel Disease.

Jactel, Samuel N. MBA 1,2; Olson, Joseph M. PhD 3; Wolin, Kathleen Y. ScD 2; Brown, Jordan MS, RD 4; Pathipati, Mythili P. MD 5,6; Jagiella, Valerie J. MD 7; Korzenik, Joshua R. MD 6,8

doi : 10.14309/ctg.0000000000000545

Most patients with irritable bowel syndrome (IBS) and dual-diagnosis IBS and inflammatory bowel disease (IBD) report that symptoms originate from or are exacerbated by trigger foods.

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Clinical Course of Medically Managed Patients With Large and Small Duct Chronic Pancreatitis.

Mahdi, Marco B. BM 1; Steinkohl, Emily MD, PhD 2; Singh, Vikesh K. MD, MSc 3; Drewes, Asbjorn M. MD, PhD, DMSc 1,4; Frokjaer, Jens B. MD, PhD 2,4; Olesen, Soren S. MD, PhD 1,4

doi : 10.14309/ctg.0000000000000537

Pancreatic duct obstruction is the primary indication for endoscopic and/or surgical therapy in patients with chronic pancreatitis (CP). However, the clinical course of medically managed patients in relation to pancreatic duct obstruction is largely unknown.

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Associations of Fecal Short Chain Fatty Acids With Colonic Transit, Fecal Bile Acid, and Food Intake in Irritable Bowel Syndrome.

Waseem, Mohammed Rayyan BS 1; Shin, Andrea MD, MSc 1; Siwiec, Robert MD 1; James-Stevenson, Toyia MD 1; Bohm, Matthew DO 1; Rogers, Nicholas MD 1; Wo, John MD 1; Waseem, Lina 1; Gupta, Anita MBBS 1; Jarrett, Megan BS 1; Kadariya, Jhalka MPH 1; Xu, Huiping PhD 2

doi : 10.14309/ctg.0000000000000541

Short-chain fatty acids (SCFAs) correlate with colonic transit time (CTT) and may influence irritable bowel syndrome (IBS) pathophysiology. However, the clinical significance of fecal SCFAs, relationships between SCFAs and other metabolites (bile acids [BAs]), and real-time diet effects on SCFAs in IBS are uncertain.

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Routine Reflux Testing Guides Timely Antireflux Treatment to Reduce Acute and Chronic Rejection After Lung Transplantation.

Lo, Wai-Kit MD, MPH 1,2,3; Goldberg, Hilary J. MD, MPH 3,4; Sharma, Nirmal MD 3,4; Wee, Jon O. MD 3,5; Chan, Walter W. MD, MPH 1,3

doi : 10.14309/ctg.0000000000000538

Gastroesophageal reflux has been associated with poorer lung transplantation outcomes, although no standard approach to evaluation/management has been adopted.

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Impact of the Second Examination of the Proximal Colon on the Adenoma Detection Rate: A Prospective Randomized Controlled Trial.

Yang, Qinyu MD, PhD 1,*; Zhu, Xiaojia MD 2,*; Wu, Zhangxuan MD 2; Leng, Fang MD 2; Shu, Xu MD, PhD 1; Yang, Li MD 2

doi : 10.14309/ctg.0000000000000557

Interval colorectal cancer identified before the next surveillance colonoscopy was more likely to be located in the proximal colon. This study aimed to determine whether a second examination of the proximal colon could increase the adenoma detection rate (ADR).

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