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Zinc supplements may prevent and treat cutaneous toxicities induced by epidermal growth factor receptor inhibitors
Margarida Gonçalo
doi : 10.1111/jdv.18835
Pioneers in Dermatology and Venereology: An Interview with Professor Annamari Ranki
Annamari Ranki
doi : 10.1111/jdv.18837
Fortuitous discoveries in dermatology
Lisa A. O'Higgins, Karen Eustace, Anne-Marie Tobin
doi : 10.1111/jdv.18507
Evaluation of risk in chronic cutaneous inflammatory conditions for malignant transformation
Teresa Ju, Loren Hernandez, Noreen Mohsin, Angelina Labib, Fabio Frech, Keyvan Nouri
doi : 10.1111/jdv.18663
Skin carcinomas are the most common form of cancer, and every year thousands of people die from skin cancer-related malignancies. Chronic inflammation is linked to the development and progression of cancer in multiple organ systems – about 20% of all human cancers are a result of chronic inflammation – skin included.
Strategies for the enhancement of nail plate permeation of drugs to treat onychomycosis
Aditya K. Gupta, Shruthi Polla Ravi, Su Yong Choi, Adarsh Konda, Elizabeth A. Cooper
doi : 10.1111/jdv.18638
Onychomycosis is caused by dermatophytes, non-dermatophytes and yeasts. It has a global prevalence of 5.5%, requires long treatment periods, and has high relapse rates following therapy.
Prevalence, comorbidities and mortality of generalized pustular psoriasis: A literature review
Jörg C. Prinz, Siew Eng Choon, Christopher E. M. Griffiths, Joseph F. Merola, Akimichi Morita, Darren M. Ashcroft, Manuelle Viguier
doi : 10.1111/jdv.18720
Generalized pustular psoriasis (GPP) is a rare auto-inflammatory skin disease characterised by acute episodes of sterile pustule formation.
Skin hyperpigmentation after sclerotherapy with polidocanol: A systematic review
Simon Bossart, Cloé Daneluzzi, Simone Cazzaniga, Albert-Adrien Ramelet, Heiko Uthoff, S. Morteza Seyed Jafari, Marc Baumgartner, Robert E. Hunger, Kristine Heidemeyer, Torsten Willenberg
doi : 10.1111/jdv.18639
Skin hyperpigmentation after sclerotherapy with polidocanol-containing sclerosants is a common local side effect. Sclerotherapists should be familiar with factors that trigger hyperpigmentation after sclerotherapy with polidocanol-containing sclerosants.
Melanoma-specific survival before and after inclusion in a familial melanoma dermatologic surveillance program in CDKN2A mutation carriers and non-carriers
Maria Pissa, Jan Lapins, Christina Sköldmark, Hildur Helgadottir
doi : 10.1111/jdv.18589
Inherited mutations in the CDKN2A gene are among the strongest known risk factors for cutaneous melanoma. Further, previous studies have reported inferior melanoma-specific survival in CDKN2A mutation carriers.
Patient presentation, skin biopsy utilization and cutaneous malignant melanoma incidence and mortality in northern Italy: Trends and correlations
Lauro Bucchi, Silvia Mancini, Federica Zamagni, Emanuele Crocetti, Luigino Dal Maso, Stefano Ferretti, Flavia Baldacchini, Orietta Giuliani, Alessandra Ravaioli, Rosa Vattiato, Angelita Brustolin, Giuseppa Candela, Simona Carone, Giuliano Carrozzi, Rossella Cavallo, Ylenia Maria Dinaro, Margherita Ferrante, Silvia Iacovacci, Guido Mazzoleni, Antonino Musolino, Roberto Vito Rizzello, Diego Serraino, Annibale Biggeri, Ignazio Stanganelli, Fabio Falcini, the AIRTUM Working Group
doi : 10.1111/jdv.18635
The global increase in incidence of cutaneous malignant melanoma (CMM) occurring in the past decades has been partly attributed to increased diagnostic scrutiny of early lesions, with a potential phenomenon of overdiagnosis. The reported positive linear relation between skin biopsy rate and incidence of early CMM is compatible with this hypothesis.
Amelanotic/hypomelanotic lentigo maligna: Dermoscopic and confocal features predicting diagnosis
Maria A. Pizzichetta, Jerry Polesel, Jean L. Perrot, Pietro Rubegni, Diletta Fiorani, Arianna Rizzo, Ignazio Stanganelli, Serena Magi, Laura Mazzoni, Matelda Medri, Michele M. Dominici, Federica Toffolutti, Francesca Farnetani, Nicola Lippolis, Gioia Pedroni, Silvana Ciardo, Alessandra G. Condorelli, Claudio Conforti, Giovanni Pellacani, Iris Zalaudek, Fabio Puglisi, Elisa Cinotti, the Italian Melanoma Intergroup (IMI), Società Italiana di Dermatologia Chirurgica, Oncologica, Correttiva ed Estetica (SIDCO), and Groupe d'imagerie cutanée non invasive de la Société Française de Dermatologie
doi : 10.1111/jdv.18636
Amelanotic/hypomelanotic lentigo maligna and lentigo maligna melanoma (AHLM/LMM) may be very difficult to diagnose at an early stage.
Impact of blood involvement on efficacy and time to response with mogamulizumab in mycosis fungoides and Sézary syndrome
Marie Beylot-Barry, Nina Booken, Carsten Weishaupt, Julia Scarisbrick, Wende Wu, Jan-Paul Rosen, Michael C. Medley
doi : 10.1111/jdv.18549
Cutaneous T-cell lymphomas (CTCL) are rare types of non-Hodgkin lymphoma, which present in skin. Mycosis fungoides (MF) and Sézary syndrome (SS) are subtypes which make up two-thirds of all CTCL cases.
Dermoscopy of haemosiderotic/aneurysmal dermatofibroma: A morphological study of 110 cases
Pedro Zaballos, Marcial Ã�lvarez-Salafranca, Àlex Llambrich, Josep Malvehy, Rosa Taberner, Carolina Medina, Giuseppe Argenziano, Luc Thomas, Ã�ngel Pizarro, Luis Javier del Pozo, Jose Antonio Avilés, Jose MarÃa Martin, Isil Karaarslan, Neus Guionnet, José Bañuls
doi : 10.1111/jdv.18664
Haemosiderotic and aneurysmal dermatofibromas are uncommon and frequently misdiagnosed lesions, which can be considered as different histopathological stages of the same tumour. A dermoscopic diagnosis testing accuracy has not been performed for these tumours to date.
Zinc deficiency associated with cutaneous toxicities induced by epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung adenocarcinoma
Chun-Wei Lu, Jong-Hwei Su Pang, Yu-Shien Ko, Chih-Jung Chang, Chuang-Wei Wang, Wei-Ti Chen, Chun-Bing Chen, Rosaline Chung-yee Hui, Shuen-Iu Hung, Lai-Ying Lu, Kun Lin Lu, Chih-Liang Wang, Chiao-En Wu, Ping-Chih Hsu, Yueh-Fu Fang, Shih-Hong Li, How-Wen Ko, Li-Chuan Tseng, Feng-Ya Shih, Mei-Jun Chen, Wen-Hung Chung
doi : 10.1111/jdv.18703
Cutaneous toxicities are common adverse effects following epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy. Zinc deficiency causes diverse diseases, including skin toxicities. Therefore, this study aimed to investigate the role of zinc deficiency in patients with EGFR-TKI-induced skin toxicities.
Mitochondrial dysfunction: The pathological link between psoriasis and insulin resistance?
Alejandra Villarreal-Martinez, Laura Elia Martinez-de-Villarreal, Minerva Gomez-Flores, Sonia Chavez-Alvarez, Ricardo Cerda-Flores, Jorge Ocampo-Candiani, Consuelo Ruiz-Herrera, Marcelo R. Rodriguez-Rivera, Jesús ZacarÃas Villarreal-Perez, José Gerardo Gonzalez-Gonzalez, Geovana Calvo-Anguiano
doi : 10.1111/jdv.18631
Psoriasis is strongly associated with insulin resistance (IR). Lipid profile disturbances and upregulation of enzymes crucial for fatty acid oxidation have been reported in patients with psoriasis. Mitochondrial ß-oxidation is altered in patients with IR. Common mitochondrial dysfunction may be involved in the origin of both diseases.
Efficacy and safety of apremilast in patients with limited skin involvement, plaque psoriasis in special areas and impaired quality of life: Results from the EMBRACE randomized trial
Ulrich Mrowietz, Jonathan Barker, Curdin Conrad, Denis Jullien, Paolo Gisondi, Andrea Flower, Jyotsna Reddy, Maria Paris, Hernan Picard, Shauna Jardon, Matthias Augustin
doi : 10.1111/jdv.18689
Manifestations of psoriasis in special areas are difficult to treat and are associated with a high disease burden and significant quality of life (QoL) impairment. Topical therapies may be inadequate for these patients, necessitating systemic treatment.
Treatment patterns and outcomes in patients with chronic urticaria during pregnancy: Results of PREG-CU, a UCARE study
Emek Kocatürk, Mona Al-Ahmad, Karoline Krause, Ana M. Gimenez-Arnau, Simon Francis Thomsen, Niall Conlon, Alexander Marsland, Ekin Savk, Roberta F. Criado, Inna Danilycheva, Daria Fomina, Kiran Godse, Maryam Khoshkhui, Aslı Gelincik, Ece Nur Degirmentepe, Semra Demir, Luis Felipe Ensina, Alicja Kasperska-Zajac, Michael Rudenko, Solange Valle, Iris Medina, Andrea Bauer, Zuotao Zhao, Petra Staubach, Laurence Bouillet, Ã–zlem Su Küçük, Arzu Baygül, Marcus Maurer
doi : 10.1111/jdv.18574
Although chronic urticaria (CU) is a common and primarily affects females, there is little data on how pregnancy interacts with the disease.
The effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis: Results from the global SECURE-AD registry
Annelie H. Musters, Conor Broderick, David Prieto-Merino, Andrea Chiricozzi, Giovanni Damiani, Ketty Peris, Sandipan Dhar, Abhishek De, Esther Freeman, Bernd W. M. Arents, Tim Burton, Angela Leigh-Ann L. Bosma, Ching-Chi Chi, Godfrey Fletcher, Aaron M. Drucker, Kenji Kabashima, Emilie F. de Monchy, Maitreyee Panda, Dmitri Robert Wall, Christian Vestergaard, Emmanuel Mahé, Laura Bonzano, Leila Kattach, Maddalena Napolitano, MarÃÂa Fernanda Ordoñez-Rubiano, Eva Haufe, Cataldo Patruno, Alan D. Irvine, Phyllis I. Spuls, Carsten Flohr
doi : 10.1111/jdv.18613
Limited data are available on the effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis (AD).
Temporal shifts of the microbiome associated with antibiotic treatment of purpuric drug eruptions related to epidermal growth factor receptor inhibitors
Paul-Chen Hsieh, Chi-Sheng Chang, Kai-Lung Chen, Yung-Tsu Cho, Chia-Yu Chu, Kuan-Yu Chen
doi : 10.1111/jdv.18640
Epidermal growth factor receptor (EGFR) inhibitors are selective and effective treatments for cancers with relevant mutations. Purpuric drug eruptions are an uncommon but clinically significant dermatological side effect related to EGFR inhibitor use that are associated with positive bacterial cultures and responsive to antibiotic treatment.
Comparison of molecular and serological assays on cerebrospinal fluid for the diagnosis of neurosyphilis
Romain Salle, Philippe A. Grange, Guillaume Ollagnier, Nadjet Benhaddou, Ugo Heller, Nicolas Dupin
doi : 10.1111/jdv.18604
Many assays are available on cerebrospinal fluid (CSF) for the diagnosis of neurosyphilis (NS) but there is no ‘gold standard’.
Development and validation of IHS4-55, an IHS4 dichotomous outcome to assess treatment effect for hidradenitis suppurativa
Thrasivoulos Tzellos, Kelsey R. van Straalen, Athanassios Kyrgidis, Afsaneh Alavi, Noah Goldfarb, Wayne Gulliver, Gregor B. E. Jemec, Michelle A. Lowes, Angelo Valerio Marzano, Errol P. Prens, Christopher J. Sayed, Hessel H. van der Zee, Christos C. Zouboulis
doi : 10.1111/jdv.18632
Validated, inclusive and easy-to-use outcomes for hidradenitis suppurativa are essential both in the clinical trial setting and clinical practice.
Epidemiology of inherited epidermolysis bullosa in Germany
Cristina Has, Moritz Hess, Waltraud Anemüller, Ulrike Blume-Peytavi, Steffen Emmert, Regina Fölster-Holst, Jorge Frank, Kathrin Giehl, Claudia Günther, Johanna Hammersen, Kathrin Hillmann, Bettina Höflein, Peter H. Hoeger, Alrun Hotz, Thuy Anh Mai, Vinzenz Oji, Holm Schneider, Kira Süßmuth, Iliana Tantcheva-Póor, Frederieke Thielking, Birgit Zirn, Judith Fischer, Antonia Reimer-Taschenbrecker
doi : 10.1111/jdv.18637
Epidermolysis bullosa (EB) is a rare genetic disorder manifesting with skin and mucosal membrane blistering in different degrees of severity.
Genotype and phenotype correlations in 441 patients with epidermolysis bullosa from China
Fuying Chen, Ruoqu Wei, Dan Deng, Xue Zhang, Yu Cao, Chaolan Pan, Yumeng Wang, Qiaoyu Cao, Jianbo Wang, Ming Zeng, Linting Huang, Yan Gu, Zhirong Yao, Ming Li
doi : 10.1111/jdv.18692
Epidermolysis bullosa (EB) is a heterogeneous group of rare and incurable genetic blistering disorders.
Porokeratosis is one of the most common genodermatoses and is associated with an increased risk of keratinocyte cancer and melanoma
Rahime Inci, Theofanis Zagoras, Despoina Kantere, Peter Holmström, Martin Gillstedt, Sam Polesie, Sirkku Peltonen
doi : 10.1111/jdv.18587
Porokeratosis is a clinically heterogeneous group of keratinization disorders with a genetic background mainly affecting the mevalonate pathway, which is involved in the synthesis of cholesterol, an essential component for the formation of the extracellular lipid lamellae in the stratum corneum.
A prospective, multicentre study to assess frailty in elderly patients with leg ulcers (GERAS study)
Nadja E. Zorge, Eveline R. Y. Scheerders, Koen Dudink, Christian Oudshoorn, Harmke A. Polinder-Bos, Rick Waalboer-Spuij, Peter M. Schlejen, Catherine van Montfrans
doi : 10.1111/jdv.18586
Although leg ulcers are a burdensome disease most common in those aged 65 years and older, frailty in this population has not yet been well established.
Superficial (nodular) thrombophlebitis as a heterogeneous entity with distinctive clinico-pathological aspects: Correlation with the underlying conditions
Lynn Gales, Bernard Cribier, Dan Lipsker, Cédric Lenormand
doi : 10.1111/jdv.18630
Superficial (nodular) thrombophlebitis, referring to a thrombo-inflammatory disorder of dermal-subcutaneous veins, encompass a spectrum of nodular lesions often associated with inflammatory, infectious, neoplastic or thrombophilic diseases.
Patient Unique Stigmatization Holistic tool in dermatology (PUSH-D): Development and validation of a dermatology-specific stigmatization assessment tool
Khaled Ezzedine, Jason Shourick, Christina Bergqvist, Laurent Misery, Bertrand Chuberre, Delphine Kerob, Bruno Halioua, Gaëlle Le Fur, Carle Paul, Marie-Aleth Richard, Charles Taieb
doi : 10.1111/jdv.18641
The skin plays an important role in establishing interpersonal relationships, and thus visible skin disorders, which have a significant impact on physical appearance, influence other people's behaviours and attitudes.
Zinc supplements may prevent and treat cutaneous toxicities induced by epidermal growth factor receptor inhibitors
Margarida Gonçalo
doi : 10.1111/jdv.18835
Pioneers in Dermatology and Venereology: An Interview with Professor Annamari Ranki
Annamari Ranki
doi : 10.1111/jdv.18837
Fortuitous discoveries in dermatology
Lisa A. O'Higgins, Karen Eustace, Anne-Marie Tobin
doi : 10.1111/jdv.18507
Evaluation of risk in chronic cutaneous inflammatory conditions for malignant transformation
Teresa Ju, Loren Hernandez, Noreen Mohsin, Angelina Labib, Fabio Frech, Keyvan Nouri
doi : 10.1111/jdv.18663
Skin carcinomas are the most common form of cancer, and every year thousands of people die from skin cancer-related malignancies. Chronic inflammation is linked to the development and progression of cancer in multiple organ systems – about 20% of all human cancers are a result of chronic inflammation – skin included.
Strategies for the enhancement of nail plate permeation of drugs to treat onychomycosis
Aditya K. Gupta, Shruthi Polla Ravi, Su Yong Choi, Adarsh Konda, Elizabeth A. Cooper
doi : 10.1111/jdv.18638
Onychomycosis is caused by dermatophytes, non-dermatophytes and yeasts. It has a global prevalence of 5.5%, requires long treatment periods, and has high relapse rates following therapy.
Prevalence, comorbidities and mortality of generalized pustular psoriasis: A literature review
Jörg C. Prinz, Siew Eng Choon, Christopher E. M. Griffiths, Joseph F. Merola, Akimichi Morita, Darren M. Ashcroft, Manuelle Viguier
doi : 10.1111/jdv.18720
Generalized pustular psoriasis (GPP) is a rare auto-inflammatory skin disease characterised by acute episodes of sterile pustule formation.
Skin hyperpigmentation after sclerotherapy with polidocanol: A systematic review
Simon Bossart, Cloé Daneluzzi, Simone Cazzaniga, Albert-Adrien Ramelet, Heiko Uthoff, S. Morteza Seyed Jafari, Marc Baumgartner, Robert E. Hunger, Kristine Heidemeyer, Torsten Willenberg
doi : 10.1111/jdv.18639
Skin hyperpigmentation after sclerotherapy with polidocanol-containing sclerosants is a common local side effect. Sclerotherapists should be familiar with factors that trigger hyperpigmentation after sclerotherapy with polidocanol-containing sclerosants.
Melanoma-specific survival before and after inclusion in a familial melanoma dermatologic surveillance program in CDKN2A mutation carriers and non-carriers
Maria Pissa, Jan Lapins, Christina Sköldmark, Hildur Helgadottir
doi : 10.1111/jdv.18589
Inherited mutations in the CDKN2A gene are among the strongest known risk factors for cutaneous melanoma. Further, previous studies have reported inferior melanoma-specific survival in CDKN2A mutation carriers.
Patient presentation, skin biopsy utilization and cutaneous malignant melanoma incidence and mortality in northern Italy: Trends and correlations
Lauro Bucchi, Silvia Mancini, Federica Zamagni, Emanuele Crocetti, Luigino Dal Maso, Stefano Ferretti, Flavia Baldacchini, Orietta Giuliani, Alessandra Ravaioli, Rosa Vattiato, Angelita Brustolin, Giuseppa Candela, Simona Carone, Giuliano Carrozzi, Rossella Cavallo, Ylenia Maria Dinaro, Margherita Ferrante, Silvia Iacovacci, Guido Mazzoleni, Antonino Musolino, Roberto Vito Rizzello, Diego Serraino, Annibale Biggeri, Ignazio Stanganelli, Fabio Falcini, the AIRTUM Working Group
doi : 10.1111/jdv.18635
The global increase in incidence of cutaneous malignant melanoma (CMM) occurring in the past decades has been partly attributed to increased diagnostic scrutiny of early lesions, with a potential phenomenon of overdiagnosis. The reported positive linear relation between skin biopsy rate and incidence of early CMM is compatible with this hypothesis.
Amelanotic/hypomelanotic lentigo maligna: Dermoscopic and confocal features predicting diagnosis
Maria A. Pizzichetta, Jerry Polesel, Jean L. Perrot, Pietro Rubegni, Diletta Fiorani, Arianna Rizzo, Ignazio Stanganelli, Serena Magi, Laura Mazzoni, Matelda Medri, Michele M. Dominici, Federica Toffolutti, Francesca Farnetani, Nicola Lippolis, Gioia Pedroni, Silvana Ciardo, Alessandra G. Condorelli, Claudio Conforti, Giovanni Pellacani, Iris Zalaudek, Fabio Puglisi, Elisa Cinotti, the Italian Melanoma Intergroup (IMI), Società Italiana di Dermatologia Chirurgica, Oncologica, Correttiva ed Estetica (SIDCO), and Groupe d'imagerie cutanée non invasive de la Société Française de Dermatologie
doi : 10.1111/jdv.18636
Amelanotic/hypomelanotic lentigo maligna and lentigo maligna melanoma (AHLM/LMM) may be very difficult to diagnose at an early stage.
Impact of blood involvement on efficacy and time to response with mogamulizumab in mycosis fungoides and Sézary syndrome
Marie Beylot-Barry, Nina Booken, Carsten Weishaupt, Julia Scarisbrick, Wende Wu, Jan-Paul Rosen, Michael C. Medley
doi : 10.1111/jdv.18549
Cutaneous T-cell lymphomas (CTCL) are rare types of non-Hodgkin lymphoma, which present in skin. Mycosis fungoides (MF) and Sézary syndrome (SS) are subtypes which make up two-thirds of all CTCL cases.
Dermoscopy of haemosiderotic/aneurysmal dermatofibroma: A morphological study of 110 cases
Pedro Zaballos, Marcial Ã�lvarez-Salafranca, Àlex Llambrich, Josep Malvehy, Rosa Taberner, Carolina Medina, Giuseppe Argenziano, Luc Thomas, Ã�ngel Pizarro, Luis Javier del Pozo, Jose Antonio Avilés, Jose MarÃa Martin, Isil Karaarslan, Neus Guionnet, José Bañuls
doi : 10.1111/jdv.18664
Haemosiderotic and aneurysmal dermatofibromas are uncommon and frequently misdiagnosed lesions, which can be considered as different histopathological stages of the same tumour. A dermoscopic diagnosis testing accuracy has not been performed for these tumours to date.
Zinc deficiency associated with cutaneous toxicities induced by epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung adenocarcinoma
Chun-Wei Lu, Jong-Hwei Su Pang, Yu-Shien Ko, Chih-Jung Chang, Chuang-Wei Wang, Wei-Ti Chen, Chun-Bing Chen, Rosaline Chung-yee Hui, Shuen-Iu Hung, Lai-Ying Lu, Kun Lin Lu, Chih-Liang Wang, Chiao-En Wu, Ping-Chih Hsu, Yueh-Fu Fang, Shih-Hong Li, How-Wen Ko, Li-Chuan Tseng, Feng-Ya Shih, Mei-Jun Chen, Wen-Hung Chung
doi : 10.1111/jdv.18703
Cutaneous toxicities are common adverse effects following epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy. Zinc deficiency causes diverse diseases, including skin toxicities. Therefore, this study aimed to investigate the role of zinc deficiency in patients with EGFR-TKI-induced skin toxicities.
Mitochondrial dysfunction: The pathological link between psoriasis and insulin resistance?
Alejandra Villarreal-Martinez, Laura Elia Martinez-de-Villarreal, Minerva Gomez-Flores, Sonia Chavez-Alvarez, Ricardo Cerda-Flores, Jorge Ocampo-Candiani, Consuelo Ruiz-Herrera, Marcelo R. Rodriguez-Rivera, Jesús ZacarÃas Villarreal-Perez, José Gerardo Gonzalez-Gonzalez, Geovana Calvo-Anguiano
doi : 10.1111/jdv.18631
Psoriasis is strongly associated with insulin resistance (IR). Lipid profile disturbances and upregulation of enzymes crucial for fatty acid oxidation have been reported in patients with psoriasis. Mitochondrial ß-oxidation is altered in patients with IR. Common mitochondrial dysfunction may be involved in the origin of both diseases.
Efficacy and safety of apremilast in patients with limited skin involvement, plaque psoriasis in special areas and impaired quality of life: Results from the EMBRACE randomized trial
Ulrich Mrowietz, Jonathan Barker, Curdin Conrad, Denis Jullien, Paolo Gisondi, Andrea Flower, Jyotsna Reddy, Maria Paris, Hernan Picard, Shauna Jardon, Matthias Augustin
doi : 10.1111/jdv.18689
Manifestations of psoriasis in special areas are difficult to treat and are associated with a high disease burden and significant quality of life (QoL) impairment. Topical therapies may be inadequate for these patients, necessitating systemic treatment.
Treatment patterns and outcomes in patients with chronic urticaria during pregnancy: Results of PREG-CU, a UCARE study
Emek Kocatürk, Mona Al-Ahmad, Karoline Krause, Ana M. Gimenez-Arnau, Simon Francis Thomsen, Niall Conlon, Alexander Marsland, Ekin Savk, Roberta F. Criado, Inna Danilycheva, Daria Fomina, Kiran Godse, Maryam Khoshkhui, Aslı Gelincik, Ece Nur Degirmentepe, Semra Demir, Luis Felipe Ensina, Alicja Kasperska-Zajac, Michael Rudenko, Solange Valle, Iris Medina, Andrea Bauer, Zuotao Zhao, Petra Staubach, Laurence Bouillet, Ã–zlem Su Küçük, Arzu Baygül, Marcus Maurer
doi : 10.1111/jdv.18574
Although chronic urticaria (CU) is a common and primarily affects females, there is little data on how pregnancy interacts with the disease.
The effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis: Results from the global SECURE-AD registry
Annelie H. Musters, Conor Broderick, David Prieto-Merino, Andrea Chiricozzi, Giovanni Damiani, Ketty Peris, Sandipan Dhar, Abhishek De, Esther Freeman, Bernd W. M. Arents, Tim Burton, Angela Leigh-Ann L. Bosma, Ching-Chi Chi, Godfrey Fletcher, Aaron M. Drucker, Kenji Kabashima, Emilie F. de Monchy, Maitreyee Panda, Dmitri Robert Wall, Christian Vestergaard, Emmanuel Mahé, Laura Bonzano, Leila Kattach, Maddalena Napolitano, MarÃÂa Fernanda Ordoñez-Rubiano, Eva Haufe, Cataldo Patruno, Alan D. Irvine, Phyllis I. Spuls, Carsten Flohr
doi : 10.1111/jdv.18613
Limited data are available on the effects of systemic immunomodulatory treatments on COVID-19 outcomes in patients with atopic dermatitis (AD).
Temporal shifts of the microbiome associated with antibiotic treatment of purpuric drug eruptions related to epidermal growth factor receptor inhibitors
Paul-Chen Hsieh, Chi-Sheng Chang, Kai-Lung Chen, Yung-Tsu Cho, Chia-Yu Chu, Kuan-Yu Chen
doi : 10.1111/jdv.18640
Epidermal growth factor receptor (EGFR) inhibitors are selective and effective treatments for cancers with relevant mutations. Purpuric drug eruptions are an uncommon but clinically significant dermatological side effect related to EGFR inhibitor use that are associated with positive bacterial cultures and responsive to antibiotic treatment.
Comparison of molecular and serological assays on cerebrospinal fluid for the diagnosis of neurosyphilis
Romain Salle, Philippe A. Grange, Guillaume Ollagnier, Nadjet Benhaddou, Ugo Heller, Nicolas Dupin
doi : 10.1111/jdv.18604
Many assays are available on cerebrospinal fluid (CSF) for the diagnosis of neurosyphilis (NS) but there is no ‘gold standard’.
Development and validation of IHS4-55, an IHS4 dichotomous outcome to assess treatment effect for hidradenitis suppurativa
Thrasivoulos Tzellos, Kelsey R. van Straalen, Athanassios Kyrgidis, Afsaneh Alavi, Noah Goldfarb, Wayne Gulliver, Gregor B. E. Jemec, Michelle A. Lowes, Angelo Valerio Marzano, Errol P. Prens, Christopher J. Sayed, Hessel H. van der Zee, Christos C. Zouboulis
doi : 10.1111/jdv.18632
Validated, inclusive and easy-to-use outcomes for hidradenitis suppurativa are essential both in the clinical trial setting and clinical practice.
Epidemiology of inherited epidermolysis bullosa in Germany
Cristina Has, Moritz Hess, Waltraud Anemüller, Ulrike Blume-Peytavi, Steffen Emmert, Regina Fölster-Holst, Jorge Frank, Kathrin Giehl, Claudia Günther, Johanna Hammersen, Kathrin Hillmann, Bettina Höflein, Peter H. Hoeger, Alrun Hotz, Thuy Anh Mai, Vinzenz Oji, Holm Schneider, Kira Süßmuth, Iliana Tantcheva-Póor, Frederieke Thielking, Birgit Zirn, Judith Fischer, Antonia Reimer-Taschenbrecker
doi : 10.1111/jdv.18637
Epidermolysis bullosa (EB) is a rare genetic disorder manifesting with skin and mucosal membrane blistering in different degrees of severity.
Genotype and phenotype correlations in 441 patients with epidermolysis bullosa from China
Fuying Chen, Ruoqu Wei, Dan Deng, Xue Zhang, Yu Cao, Chaolan Pan, Yumeng Wang, Qiaoyu Cao, Jianbo Wang, Ming Zeng, Linting Huang, Yan Gu, Zhirong Yao, Ming Li
doi : 10.1111/jdv.18692
Epidermolysis bullosa (EB) is a heterogeneous group of rare and incurable genetic blistering disorders.
Porokeratosis is one of the most common genodermatoses and is associated with an increased risk of keratinocyte cancer and melanoma
Rahime Inci, Theofanis Zagoras, Despoina Kantere, Peter Holmström, Martin Gillstedt, Sam Polesie, Sirkku Peltonen
doi : 10.1111/jdv.18587
Porokeratosis is a clinically heterogeneous group of keratinization disorders with a genetic background mainly affecting the mevalonate pathway, which is involved in the synthesis of cholesterol, an essential component for the formation of the extracellular lipid lamellae in the stratum corneum.
A prospective, multicentre study to assess frailty in elderly patients with leg ulcers (GERAS study)
Nadja E. Zorge, Eveline R. Y. Scheerders, Koen Dudink, Christian Oudshoorn, Harmke A. Polinder-Bos, Rick Waalboer-Spuij, Peter M. Schlejen, Catherine van Montfrans
doi : 10.1111/jdv.18586
Although leg ulcers are a burdensome disease most common in those aged 65 years and older, frailty in this population has not yet been well established.
Superficial (nodular) thrombophlebitis as a heterogeneous entity with distinctive clinico-pathological aspects: Correlation with the underlying conditions
Lynn Gales, Bernard Cribier, Dan Lipsker, Cédric Lenormand
doi : 10.1111/jdv.18630
Superficial (nodular) thrombophlebitis, referring to a thrombo-inflammatory disorder of dermal-subcutaneous veins, encompass a spectrum of nodular lesions often associated with inflammatory, infectious, neoplastic or thrombophilic diseases.
Patient Unique Stigmatization Holistic tool in dermatology (PUSH-D): Development and validation of a dermatology-specific stigmatization assessment tool
Khaled Ezzedine, Jason Shourick, Christina Bergqvist, Laurent Misery, Bertrand Chuberre, Delphine Kerob, Bruno Halioua, Gaëlle Le Fur, Carle Paul, Marie-Aleth Richard, Charles Taieb
doi : 10.1111/jdv.18641
The skin plays an important role in establishing interpersonal relationships, and thus visible skin disorders, which have a significant impact on physical appearance, influence other people's behaviours and attitudes.
Regression of common viral warts in an immunocompetent child and an immunosuppressed adult relative after mRNA BNT162b2 COVID-19 vaccine
Maria Dalamaga, Dimitrios Tsilingiris, Alexandros Katoulis
doi : 10.1111/jdv.18577
A case of Anti-MDA5-Positive dermatomyositis after inactivated COVID-19 vaccine
Lili Yang, Tinglu Ye, Huanyu Liu, Cong Huang, Weiwei Tian, Yueming Cai
doi : 10.1111/jdv.18653
Reply to ‘Impact of the French COVID-19 pandemic lockdown on newly diagnosed melanoma delay and severity’ by R. Molinier et al.
Angelo Ruggiero, Fabrizio Martora, Fabrizio Fornaro, Massimiliano Scalvenzi, Gabriella Fabbrocini, Alessia Villani
doi : 10.1111/jdv.18512
A cross-sectional study of dermatologists' attitudes towards COVID-19 vaccination in patients with immunobullous diseases
Michael Kasperkiewicz, Rebecca Strong, Marc Yale, Patrick Dunn, David T. Woodley
doi : 10.1111/jdv.18674
Severe bullous pemphigoid following Covid-19 vaccination resistant to rituximab and successfully treated with dupilumab
Maria E. Baffa, Roberto Maglie, Francesca Montefusco, Carlo Pipitò, Stefano Senatore, Emiliano Antiga
doi : 10.1111/jdv.18673
COVID-19 vaccine side effects in patients with and without atopic dermatitis
Leah Shin, Shahin Shahsavari, Jennifer Laborada, Claudia Lee, Jacob Pontoppidan Thyssen, Jashin J. Wu
doi : 10.1111/jdv.18710
Reply to ‘A case of pityriasis lichenoides et varioliformis acuta developed after first dose of Oxford-AstraZeneca COVID-19 vaccine’
Fabrizio Martora, Gabriella Fabbrocini, Gianluca Guerrasio, Luca Potestio
doi : 10.1111/jdv.18646
Female genital mucosal lesions associated with COVID-19 vaccination: A brief review of the literature
Antonella Tammaro, Karolina Anna Kulakowska, Carmen Cantisani, Francesca Romana Parisella, Alessandra Scarabello, Ganiyat Adenike Ralitsa Adebanjo
doi : 10.1111/jdv.18711
Gianotti-crosti syndrome after COVID-19 vaccination
Sarah Janßen, Bernhard Homey, Stephan Meller
doi : 10.1111/jdv.18626
A prospective case control study of resistance to rifampicin, dapsone and ofloxacin in Type 1 and Type 2 leprosy reactions and the therapeutic impact of modified treatment regimen on reactions
Aishwarya Muddebihal, Kabir Sardana, Ananta Khurana, Soumya Sachdeva, Itu Singh, Madhvi Ahuja, Rahul Sharma
doi : 10.1111/jdv.18709
Halo-like phenomenon in neurofibromatosis type 1: A potential new diagnostic criterion
Jia Zhang, Qianyue Xu, Jinwen Shen, Ming Li, Zhirong Yao
doi : 10.1111/jdv.18517
Can people take high-quality images using mobile dermatoscopes at home on easy-to-see and difficult-to-see body areas?
Astrid J. Rodriguez-Acevedo, Montana O'Hara, Uyen Koh, Brigid Betz-Stablein, Caitlin Horsham, H. Peter Soyer, Monika Janda
doi : 10.1111/jdv.18633
Neurofibromatosis type 1: Factors associated with flare-ups of cutaneous neurofibromas at puberty
Charbel Skayem, Laura Fertitta, Emmanuelle Diaz, Arnaud Jannic, Salah Ferkal, Philippe Ravaud, Viet-Thi Tran, Khaled Ezzedine, Pierre Wolkenstein
doi : 10.1111/jdv.18652
Dyshidrosiform pemphigoid induced by ustekinumab in a patient with ulcerative colitis
Dario Didona, Tomas Cunha, Julia Hinterseher, Hazem A. Juratli, Stefan Mühlenbein, Michael Hertl
doi : 10.1111/jdv.18686
Resilience of patients with skin diseases in France: A cross-sectional study
Bruno Halioua, Christine Patras de Campaigno, Stéphanie Merhand, Benedicte Charles, Marie France Bru, Clemence Legrand, Christopher Beausillon, Helene Raynal, Charles Taieb, Marie-Aleth Richard
doi : 10.1111/jdv.18681
A novel KRT16 frameshift variant causing pachyonychia congenita by re-initiation of translation
Sai Wang, Qianqian Bai, Mingyang Lee, Zhimiao Lin, Liangqi Cai, Huijun Wang
doi : 10.1111/jdv.18580
Topical simvastatin ointment improves xanthoma disseminatum lesions
Siyuan Zha, Yan Gu, Zhirong Yao, Xia Yu
doi : 10.1111/jdv.18659
No effect of topical digoxin and furosemide for patients with actinic keratosis
Bertine W. Huisman, Lauren E. H. Nené, Feeke L. L. Linders, Tom K. Gambrah, Tessa Niemeyer van der Kolk, Marieke L. de Kam, Jan Nico Bouwes Bavinck, Jacobus Burggraaf, Gary Feiss, Robert Rissmann
doi : 10.1111/jdv.18624
The impact of dermatitis on health-related quality of life: Data from the National Health and Nutrition Examination Survey
Yong Lee, Morgan Ye, Janell Tully, Samir Salah, Delphine Kerob, Katrina Abuabara
doi : 10.1111/jdv.18600
Prevalence of visible skin diseases: An international study of 13,138 people
Bernard Cribier, Marketa Saint Aroman, Stéphanie Merhand, Roberte Aubert, Anne Audouze, Clemence Legrand, Martine Carre, Helene Raynal, Catherine Baissac, Charles Taieb, Marie Aleth Richard
doi : 10.1111/jdv.18666
Alopecia diagnoses in patients presenting to a specialty alopecia clinic with pityriasis amiantacea
Maya S. Collins, Shaheir Ali, Kristen Kelley, Emma Stratton, Maryanne M. Senna
doi : 10.1111/jdv.18670
Liver metastases and immunotherapy: A barrier to response for metastatic melanoma
Marco Rubatto, Nicole Macagno, Ginevra Pastorin, Paolo Fava, Luca Ceroni, Simone Ribero, Pietro Quaglino
doi : 10.1111/jdv.18590
Dapsone in non-bullous skin lesions of lupus erythematosus: AÂ literature review
Gaelle Marzolf, Dan Lipsker
doi : 10.1111/jdv.18620
Risk factor-specific mortality in herpes zoster in a retrospective cohort study: The neutrophil-to-lymphocyte ratio is a useful biomarker for predicting late-onset complications resulting in death
Takenobu Yamamoto, Yumi Aoyama
doi : 10.1111/jdv.18602
Burnout among French dermatologists: A national study
Nicole Jouan, Charles Taieb, Bruno Halioua
doi : 10.1111/jdv.18492
Risk of cardiovascular diseases in pyoderma gangrenosum: A population-based study
Eran Shavit, Or Dagan, Arnon D. Cohen, Yuliya Valdman-Grinshpoun, Khalaf Kridin
doi : 10.1111/jdv.18527
Clinical utility of liquid biopsy for monitoring patients with NRAS-mutant medium-to-giant congenital melanocytic nevi
Neus Calbet-Llopart, Gemma Tell-MartÃÂ, Judit Mateu, Marta Feito, Silvestre MartÃÂnez, Susana Puig, Josep Malvehy, Cristina Carrera, Joan A. Puig-Butillé
doi : 10.1111/jdv.18584
Cutaneous vasculitis associated with mycosis fungoides
Charlée Nardin, Candice Lesage, Eléonore Goubeau, Marie-Helene Aubriot-Lorton, Vanessa Lacheretz-Szablewski, Nicolas Ortonne, Ines Saizonou, François Aubin, Olivier Dereure, Sophie Dalac-Rat
doi : 10.1111/jdv.18657
Drug-induced photosensitivity during tebentafusp treatment for metastatic uveal melanoma: A newly described occurrence
Martina Lambertini, Francesca Comito, Barbara Melotti, Maria Francesca Baracca, Emi Dika
doi : 10.1111/jdv.18625
Electrochemotherapy under analgosedation – Case report of a patient with Kaposi's sarcoma
Vanessa Pfefferle, Ulrike Leiter, Teresa Grünke, Katrin Kofler, Hans-Martin Häfner, Lukas Kofler
doi : 10.1111/jdv.18518
A novel and effective therapy for Zoon balanitis: Topical crisaborole 2% ointment
Xuping Niu, Xuyan Yang, Fang Wang, Ruixia Hou, Lifeng Yao, Qixin Han, Yeqiang Liu
doi : 10.1111/jdv.18494
Epidermolysis bullosa pruriginosa with extensive truncal involvement treated with upadacitinib
Nayoung Kim, Mihn-Sook Jue, Yun Jung Huh, Kyung Jeh Sung, Hyunsung Kim, Jeong Eun Kim, Joo Yeon Ko
doi : 10.1111/jdv.18487
A rare and challenging presentation of adult-onset pansclerotic morphea
Nathalia Chebli de Abreu, Filipe Didier Maciel, Eduardo José do Rosário e Souza, Ana Júlia Batista Perdigão Mendes, Sandra Lyon
doi : 10.1111/jdv.18522
Penile histoplasmosis in an immunocompetent host: A rare intruder in genital ulcer
Ankita Choudhary, Neha Chetan Jangid, Bela Shah
doi : 10.1111/jdv.18675
Human papilloma virus vaccine for palmoplantar warts: A retrospective study of 18 patients
Léa Merio, Johan Chanal, Marie Jachiet, Valérie Pourcher, Jean Philippe Arnault, Christelle Jouhet, Brigitte Milpied-Homsi, Isabelle Bourgault-Villada, Francois Aubin, Frédéric Caux, Sébastien Fouéré, Eric Vicaut, Marie Beylot-Barry, Olivier Chosidow, with the support of the GrIDIST
doi : 10.1111/jdv.18523
A rare case of adrenergic urticaria in a child
Benjamin Schnebert, Laurence de Montjoye, Marie Baeck
doi : 10.1111/jdv.18497
Reply to ‘A rare case of adrenergic urticaria in a child’ by Schnebert et al.
David Pesqué, Ramon Maria Pujol, Ana Maria Giménez-Arnau
doi : 10.1111/jdv.18651
Scar diastasis index: a smart and reproducible tool to evaluate long-standing scars
Stefano Astorino, Donato Di Nunno, Giorgio Troiani, Alessandro Laghi
doi : 10.1111/jdv.18610
Authors' reply to: ‘Generalized pustular figurate erythema first report in two COVID-19 patients on hydroxychloroquine’
Martina Bertello, Giovanni Rubegni, Pietro Rubegni, Linda Tognetti
doi : 10.1111/jdv.18486
Association of atopic dermatitis with new-onset migraine: AÂ nationwide population-based cohort study
Ji Hae Lee, Soo Hyung Kim, Gyu-na Lee, Kyungdo Han, Ji Hyun Lee
doi : 10.1111/jdv.18680
A challenging case of contact allergy to corticosteroids: The value of epicutaneous testing not only for etiologic diagnosis but also to prevent severe systemic reactions
Rossella Marietti, Marta Tramontana, Katharina Hansel, Leonardo Bianchi, Nicolò Malatesta, Luca Stingeni
doi : 10.1111/jdv.18658
Superficial thrombophlebitis of the lower limb after tattooing
Nicolas Kluger
doi : 10.1111/jdv.18551
Cocaine-induced plasma cell orificial mucositis
Begoña Udondo González del Tánago, David Jiménez-Gallo, Irene Navarro-Navarro, Inmaculada Catalina-Fernández, Juan José RÃÂos-MartÃÂn, Mario Linares-Barrios
doi : 10.1111/jdv.18619
Drug reaction with eosinophilia and systemic symptoms with features resembling Stevens–Johnson syndrome/toxic epidermal necrolysis related to apalutamide
Yun-Shiuan Olivia Hsu, Tyng-Shiuan Hsieh, Po-Wei Huang, Chia-Yu Chu
doi : 10.1111/jdv.18660
Anti-β4 integrin autoantibodies in patients with mucous membrane pemphigoid: A retrospective analysis from a tertiary centre in Italy
Roberto Maglie, Carolina Vieira De Almeida, Maria Efenesia Baffa, Beatrice Bianchi, Marzia Caproni, Giovanni Di Zenzo, Xiaoguang Li, Yoshiaki Hirako, Takashi Hashimoto, Ignazia Tusa, Matteo Lulli, Elisabetta Rovida, Emiliano Antiga
doi : 10.1111/jdv.18617
Increased skin pH and transepidermal water loss may serve as predictor for atopic dermatitis flares
Alessandra Marini, Natalie Aue, Anne-Laure Demessant, Samir Salah, Delphine Kerob, Thomas A. Luger
doi : 10.1111/jdv.18558
Complication rate of wide local excision in patients with pT1a melanoma
Tessa M. A. van Henten, Sandrine G. Goris, Nicole A. Kukutsch, Marieke E. Straver, Lydia E. Vos
doi : 10.1111/jdv.18583
Bendamustine monochemotherapy in aggressive or advanced-stage primary cutaneous T-cell lymphomas
Alena-Lioba Michalowitz, Sven-Niklas Burmann, Frank Oellig, Chalid Assaf, Lorenzo Cerroni, Alexander Kreuter
doi : 10.1111/jdv.18691
Should we customize the treatment with interleukin-17A inhibitors for moderate-to-severe psoriasis in the real-world setting?
Kun Hu, Mi Zhang, Jing Yang, Qiaolin Wang, Minjia Tan, Sichun Deng, Junchen Chen, Wu Zhu, Wendong Chen, Yehong Kuang, Xiang Chen
doi : 10.1111/jdv.18678
Outbreak of monkeypox in an STD clinic in Lisbon
Margarida Caldeira, Cândida Fernandes, José Neves, Alexandre João, Rebeca Calado, Ana Raquel Pinto, Maria José Borrego, Rita Cordeiro, Jorge Machado, Ana Pelerito, Isabel Lopes de Carvalho, Luis Vieira, Maria Sofia Núncio, Maria João Paiva Lopes
doi : 10.1111/jdv.18679
