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Anesthesiology.
doi : 10.1097/ALN.0000000000004493
Volume 138(2) pgs. A3-A11,129-233 February 2023
Ring Around the Rocuronium: Sugammadex Encapsulation Explained BIT by BIT.
Ende, Holly B. 1; Rathmell, James P. 2; Wanderer, Jonathan P. 3
Instructions for Obtaining ANESTHESIOLOGY Continuing Medical Education (CME) Credit.
Anesthesia, Coming of Age in the World of Modern In Silico Drug Design.
Bertaccini, Edward J. M.D. 1
2023 American Society of Anesthesiologists Practice Guidelines for Preoperative Fasting: Carbohydrate-containing Clear Liquids with or without Protein, Chewing Gum, and Pediatric Fasting Duration-A Modular Update of the 2017 American Society of Anesthesiologists Practice Guidelines for Preoperative Fasting*.
Joshi, Girish P. M.B.B.S., M.D.; (Co-Chair); Abdelmalak, Basem B. M.D.; (Co-Chair); Weigel, Wade A. M.D.; Harbell, Monica W. M.D.; Kuo, Catherine I. M.D.; Soriano, Sulpicio G. M.D.; Stricker, Paul A. M.D.; Tipton, Tommie B.S.N., R.N., C.N.O.R.; Grant, Mark D. M.D., Ph.D.; Marbella, Anne M. M.S.; Agarkar, Madhulika M.P.H.; Blanck, Jaime F. M.L.I.S., M.P.A.; Domino, Karen B. M.D., M.P.H.
doi : 10.1097/ALN.0000000000004381
AB These practice guidelines are a modular update of the "Practice guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: Application to healthy patients undergoing elective procedures." The guidance focuses on topics not addressed in the previous guideline: ingestion of carbohydrate-containing clear liquids with or without protein, chewing gum, and pediatric fasting duration. Copyright (C) by 2023, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. All Rights Reserved.
Encapsulation Dynamics of Neuromuscular Blocking Drugs by Sugammadex.
Irani, Amir Hossein Ph.D. 1; Voss, Logan Ph.D. 2; Whittle, Nicola M.B.Ch.B. 3; Sleigh, Jamie W. M.D. 4
doi : 10.1097/ALN.0000000000004442
The clinical actions of sugammadex have been well studied, but the detailed molecular mechanism of the drug encapsulation process has not been systematically documented.
Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial.
Shin, Hyun-Jung M.D., Ph.D. 1; Woo Nam, Sun M.D. 2; Kim, Heeyeon M.D. 3; Yim, Subin M.D. 4; Han, Sung-Hee M.D., Ph.D. 5; Hwang, Jung-Won M.D., Ph.D. 6; Do, Sang-Hwan M.D., Ph.D. 7; Na, Hyo-Seok M.D., Ph.D. 8
doi : 10.1097/ALN.0000000000004438
Delirium is a critical postoperative complication in older patients. Based on the hypothesis that intraoperative dexmedetomidine sedation would lower postoperative delirium than propofol sedation would, the authors compared the incidence of postoperative delirium in older adults, using the mentioned sedatives.
Prevention of Postoperative Cognitive Dysfunction by Minocycline in Elderly Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Clinical Trial.
Takazawa, Tomonori M.D., Ph.D. 1; Horiuchi, Tatsuo M.D., Ph.D. 2; Orihara, Masaki M.D., Ph.D. 3; Nagumo, Kazuhiro M.D. 4; Tomioka, Akihiro M.D., Ph.D. 5; Ideno, Yuki Ph.D. 6; Hayashi, Kunihiko Ph.D. 7; Yashima, Hideaki Ph.D. 8; Araki, Takuya Ph.D. 9; Hatayama, Kazuhisa M.D., Ph.D. 10; Terauchi, Masanori M.D., Ph.D. 11; Ikeda, Yoshio M.D., Ph.D. 12; Saito, Shigeru M.D., Ph.D. 13
doi : 10.1097/ALN.0000000000004439
There are no effective pharmacologic interventions for preventing postoperative cognitive dysfunction in daily practice. Since the antibiotic minocycline is known to suppress postoperative neuroinflammation, this study hypothesized and investigated whether minocycline might have a preventive effect on postoperative cognitive dysfunction after noncardiac surgery.
Postoperative Acute Kidney Injury by Age and Sex: A Retrospective Cohort Association Study.
Privratsky, Jamie R. M.D., Ph.D. 1; Fuller, Matthew M.S. 2; Raghunathan, Karthik M.B.B.S., M.P.H. 3; Ohnuma, Tetsu M.D., M.P.H. 4; Bartz, Raquel R. M.D. 5; Schroeder, Rebecca M.D. 6; Price, Thomas M. M.D. 7; Martinez, Michael R. M.D. 8; Sigurdsson, Martin I. M.D., Ph.D. 9; Mathis, Michael R. M.D. 10; Naik, Bhiken M.B.B.Ch., M.S.C.R. 11; Krishnamoorthy, Vijay M.D., M.P.H., Ph.D. 12
doi : 10.1097/ALN.0000000000004436
Acute kidney injury (AKI) after noncardiac surgery is common and has substantial health impact. Preclinical and clinical studies examining the influence of sex on AKI have yielded conflicting results, although they typically do not account for age-related changes.
Nonopioid Analgesic Prescriptions Filled after Surgery among Older Adults in Ontario, Canada: A Population-based Cohort Study.
Jivraj, Naheed K. M.B.B.S., M.Sc. 1; Ladha, Karim S. M.D., M.Sc. 2; Goel, Akash M.D., M.Sc. 3; Hill, Andrea Ph.D. 4; Wijeysundera, Duminda N. M.D., Ph.D. 5; Bateman, Brian T. M.D., M.Sc. 6; Neuman, Mark M.D., M.Sc. 7; Wunsch, Hannah M.D., M.Sc. 8
doi : 10.1097/ALN.0000000000004443
The objective was to assess changes over time in prescriptions filled for nonopioid analgesics for older postoperative patients in the immediate postdischarge period.
For Science and Humanity: Vivisection and the Rise of Experimental Physiology.
Modulation of Cerebral Function by Muscle Afferent Activity, with Reference to Intravenous Succinylcholine.
Lanier, William L. M.D. 1
doi : 10.1097/ALN.0000000000004437
AB Cerebral Function and Muscle Afferent Activity Following Intravenous Succinylcholine in Dogs Anesthetized with Halothane: The Effects of Pretreatment with a Defasciculating Dose of Pancuronium. By WL Lanier, PA Iaizzo, and JH Milde.
Coronary Artery Air Embolism in the Non-operating room Anesthesia Setting.
Oesterling, Anne Elizabeth M.D. 1; Kenlan, Dasha E. M.D. 2; Cizman, Ziga M.D. 3
Cold-stored Platelets for Bleeding Patients: Comment.
Choi, Warren M.D.; Liang, Yafen M.D. 1
Cold-stored Platelets for Bleeding Patients: Comment.
Grocott, Hilary P. M.D., F.R.C.P.C., F.A.S.E. 1; Grant, Laurel M.D.
Pectoral Nerve Blocks for Breast Augmentation Surgery: Comment.
Sethuraman, Raghuraman M. M.D. 1
Pectoral Nerve Blocks for Breast Augmentation Surgery: Comment.
Xue, Fu-Shan M.D. 1; He, Nong M.D.; Li, Cheng-Wen M.D.
N-Acetylcysteine and Postoperative Atrial Fibrillation: Comment.
Kinoshita, Hiroyuki M.D., Ph.D. 1; Kawashima, Shingo M.D., Ph.D.
N-Acetylcysteine and Postoperative Atrial Fibrillation: Comment.
Wen, Junlin Ph.D. 1; Huang, Weizhao M.D.; Li, Binfei M.D.
N-Acetylcysteine and Postoperative Atrial Fibrillation: Reply.
Amar, David M.D. 1; Chung, Mina K. M.D.; Jones, David R. M.D.
Liposomal Bupivacaine versus Dexamethasone: Comment.
Yu, Vincent Ph.D.; DiGiorgi, Mary M.P.H., Ph.D. 1; Winston, Roy M.D.
Liposomal Bupivacaine versus Dexamethasone: Reply.
Kim, David H. M.D. 1; Liu, Jiabin M.D., Ph.D.; Wu, Christopher L. M.D.; Memtsoudis, Stavros G. M.D., Ph.D., M.B.A.
Liposomal Bupivacaine versus Dexamethasone: Comment.
Karim, Habib Reazaul Md M.D., D.N.B., I.D.C.C.M., F.N.I.V. 1; Bhakta, Pradipta M.D., D.N.B., F.C.A.I., E.D.R.A., E.D.I.C.; O'Brien, Brian F.C.A.R.C.S.I., F.J.F.I.C.M.I., F.C.I.C.M. (A.N.Z.).
Liposomal Bupivacaine versus Dexamethasone: Reply.
Kim, David H. M.D. 1; Liu, Jiabin M.D., Ph.D.; Wetmore, Douglas M.D.; Kim, Sang Jo M.D.
The Desperate Hours: One Hospital's Fight to Save a City on the Pandemic's Front Lines.
McGoldrick, Kathryn Elizabeth M.D., F.C.A.I. (Hon). 1
Prophylactic Penehyclidine Inhalation for Prevention of Postoperative Pulmonary Complications in High-risk Patients: A Double-blind Randomized Trial: Erratum.
Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial: Erratum.
