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Issue Highlights page
doi : 10.1016/S0360-3016(22)03648-3
Volume 115, Issue 3, 1 March 2023, Pages A9-A11
Hits and Misses in Novel Pancreatic and Rectal Cancer Treatment Options
Michael D. Chuong, MD,* Christopher J. Anker, MD,y Michael H. Buckstein, MD, PhD,z Maria A. Hawkins, MD,x Jordan Kharofa, MD,â•‘ Ann C. Raldow, MD, MPH,{ Nina N. Sanford, MD, # Andrzej Wojcieszysnki, MD,** and Jeffrey R. Olsen, MD
doi : 10.1016/j.ijrobp.2022.10.022
Volume 115, Issue 3, 1 March 2023, Pages 545-552
Atypical Nodal Involvement From an Atypical Meningioma
David M. Francis, MD, and Jeffrey V. Brower, MD, PhD
doi : 10.1016/j.ijrobp.2022.07.030
Volume 115, Issue 3, 1 March 2023, Pages 553-554
Protons or Photons – Let's Get It Done
Felix Ehret, MD Helen A. Shih, MD
doi : 10.1016/j.ijrobp.2022.08.005
Volume 115, Issue 3, 1 March 2023, Page 555
Definitive Treatment of an Atypical Case
Andrew B. Barbour, MD, PhD Lia M. Halasz, MD
doi : 10.1016/j.ijrobp.2022.08.008
Volume 115, Issue 3, 1 March 2023, Pages 555-556
Modern Meningioma Methods: Molecular Diagnostics and High Dose Protons
Rupesh Kotecha, MD Minesh P. Mehta, MD
doi : 10.1016/j.ijrobp.2022.09.074
Volume 115, Issue 3, 1 March 2023, Page 556
Geographic Accessibility of Radiation Therapy Facilities in Sub-Saharan Africa
Pranay Nadella, MPhil,* Hari S. Iyer, ScD,y Achille Manirakiza, MD,z Verna Vanderpuye, MBChB,x Scott A. Triedman, MD,k,{ Lawrence N. Shulman, MD, # and Temidayo Fadelu, MD, MPH
doi : 10.1016/j.ijrobp.2022.10.018
Volume 115, Issue 3, 1 March 2023, Pages 557-563
An Introduction to Meta-Analysis
Eric J. Lehrer, MD, MS,* Ming Wang, PhD,y,z Yilun Sun, PhD,y,z and Nicholas G. Zaorsky, MD, MS
doi : 10.1016/j.ijrobp.2022.07.1831
Volume 115, Issue 3, 1 March 2023, Pages 564-571
Effects of Proton Craniospinal Radiation on Vertebral Body Growth Retardation in Children
Myrsini Ioakeim-Ioannidou, MD,* Drosoula Giantsoudi, PhD,* Andrzej Niemierko, PhD,* Roshan Sethi, MD,* Daniel W. Kim, MD, MBA,* Torunn I. Yock, MD,* Nancy J. Tarbell, MD,* F. Joseph Simeone, MD,y and Shannon M. MacDonald, MD
doi : 10.1016/j.ijrobp.2022.08.055
Volume 115, Issue 3, 1 March 2023, Pages 572-580
Pediatric Craniopharyngioma: The Effect of Visual Deficits and Hormone Deficiencies on Long-Term Cognitive Outcomes After Conformal Photon Radiation Therapy
Thomas E. Merchant, DO, PhD,* Sonal Dangda, MBBS, MS,y,z Mary Ellen Hoehn, MD,y,z Shengjie Wu, MS,x Yimei Li, PhD,x Fang Wang, MS,x Haitao Pan, PhD,x Frederick A. Boop, MD,y Niki Jurbergs, PhD,â•‘ and Heather M. Conklin, PhD
doi : 10.1016/j.ijrobp.2022.09.061
Volume 115, Issue 3, 1 March 2023, Pages 581-591
Nitroglycerin Plus Whole Intracranial Radiation Therapy for Brain Metastases in Patients With Non-Small Cell Lung Cancer: A Randomized, Open-Label, Phase 2 Clinical Trial
Oscar Arrieta, MSc,* Norma Hernandez-Pedro, PhD,*,y Federico Maldonado, PhD,z Maritza Ramos-RamÃrez, MD,* Masao Yamamoto-Ramos, MD,y Diego Lopez-MacÃas, MD,* Francisco Lozano, MD,z Zyanya Lucia Zatarain-Barron, MSc,* Jenny G. Turcott, PhD,* Pedro Barrios-Bernal, BSc,y Mario Orozco-Morales, PhD,y Diana Flores-Estrada, LSW,* Andres F. Cardona, PhD,x,â•‘ Christian Rolfo, PhD,{ and Bernardo Cacho-DÃaz, MSc*
doi : 10.1016/j.ijrobp.2022.02.010
Volume 115, Issue 3, 1 March 2023, Pages 592-607
Emerging Role of Immunomonitoring to Predict the Clinical Outcome of Patients With Malignant Pleural Mesothelioma Treated With Radical Radiation Therapy
Michela Cangemi, PhD,* Marcella Montico, MSc,y Marco Trovo, MD,z Emilio Minatel, MD,x Emanuela Di Gregorio, PhD,║ Giuseppe Corona, ScD,║ Fabiana Giordari, MLT,║ Elisa Comaro, MLT,║ Francesca Colizzi, MLT,║ Lorena Babo ̧ci, PhD,║ Agostino Steffan, MD,║ Alberto Revelant, MD,x and Elena Muraro, PhD
doi : 10.1016/j.ijrobp.2022.09.079
Volume 115, Issue 3, 1 March 2023, Pages 608-621
Outcomes of Breast Cancer Patients with High Volume of Residual Disease Following Neoadjuvant Chemotherapy
Y. Helen Zhang, MD,* Giacomo Montagna, MD, MPH,y Jessica Flynn, MS,z Erin F. Gillespie, MD,* Anita Mamtani, MD,y Zhigang Zhang, PhD,z Lior Z. Braunstein, MD,* Simon N. Powell, MD, PhD,* Monica Morrow, MD,y Andrea Barrio, MD,y and Atif J. Khan, MD*
doi : 10.1016/j.ijrobp.2022.09.065
Volume 115, Issue 3, 1 March 2023, Pages 622-628
Optimizing Preventive Adjuvant Linac-Based (OPAL) Radiation: A Phase 2 Trial of Daily Partial Breast Irradiation
Jay P. Reddy, MD, PhD,* Xiudong Lei, PhD,y Elizabeth S. Bloom, MD,* Valerie K. Reed, MD,* Pamela J. Schlembach, MD,* Isidora Arzu, MD,* Lauren Mayo, MD,* Stephen G. Chun, MD,* Neelofur R. Ahmad, MD,* Michael C. Stauder, MD,* Ramesh Gopal, MD,* Kels Kaiser, MS,* Penny Fang, MD, MBA,* and Benjamin D. Smith, MD*,y on behalf of the OPAL Trial Investigators
doi : 10.1016/j.ijrobp.2022.09.083
Volume 115, Issue 3, 1 March 2023, Pages 629-644
External Beam Radiation Therapy With or Without Brachytherapy Boost in Men With Very-High-Risk Prostate Cancer: A Large Multicenter International Consortium Analysis
Sagar A. Patel, MD,* Ting Martin Ma, MD, PhD,y Jessica K. Wong, MD,z Bradley J. Stish, MD,x Robert T. Dess, MD,k Avinash Pilar, MD,{,# Chandana Reddy, MS,** Trude B. Wedde, MD,yy Wolfgang A. Lilleby, MD, PhD,yy Ryan Fiano, MPH,zz Gregory S. Merrick, MD,zz Richard G. Stock, MD,xx D. Jeffrey Demanes, MD,y Brian J. Moran, MD,kk Phuoc T. Tran, MD, PhD,{{ Daniel J. Krauss, MD, ## Eyad I. Abu-Isa, MD,k Thomas M. Pisansky, MD,x C. Richard Choo, MD,x Daniel Y. Song, MD,*** Stephen Greco, MD,*** Curtiland Deville, MD,*** Theodore L. DeWeese, MD,*** Derya Tilki, MD,yyy Jay P. Ciezki, MD,** R. Jeffrey Karnes, MD,zzz Nicholas G. Nickols, MD, PhD,y Matthew B. Rettig, MD,xxx Felix Y. Feng, MD, PhD,kkk Alejandro Berlin, MD, MSc,{ Jonathan D. Tward, MD, PhD,{{{ Brian J. Davis, MD, PhD,x Robert E. Reiter, MD, ### Paul C. Boutros, PhD,### Tahmineh Romero, MS,**** Eric M. Horwitz, MD,z Rahul D. Tendulkar, MD,** Michael L. Steinberg, MD,y Daniel E. Spratt, MD,yyyy Michael Xiang, MD, PhD,y and Amar U. Kishan, MD
doi : 10.1016/j.ijrobp.2022.09.075
Volume 115, Issue 3, 1 March 2023, Pages 645-653
GEC-ESTRO (ACROP)–ABS–CBG Consensus Brachytherapy Target Definition Guidelines for Recurrent Endometrial and Cervical Tumors in the Vagina
Mitchell Kamrava, MD, MHDS,* Eric Leung, MD,y Francois Bachand, MD,z Sushil Beriwal, MD, MBA,x Cyrus Chargari, MD, PhD,k David D’Souza, MD,{ Beth Erickson, MD, # Lars Fokdal, MD, PhD,** Kathy Han, MD,yy Matthew Harkenrider, MD,zz Lilie Lin, MD,xx Umesh Mahantshetty, MD,kk Nicole Nesvacil, PhD,{{ Ananth Ravi, PhD,y Max Schmid, MD,{{ Eric Vigneault, MD, ## Henrike Westerveld, MD, PhD,*** Catheryn Yashar, MD,yyy and Remi Nout, MD, PhD
doi : 10.1016/j.ijrobp.2022.09.072
Volume 115, Issue 3, 1 March 2023, Pages 654-663
Online Symptom Monitoring During Pelvic Radiation Therapy: Randomized Pilot Trial of the eRAPID Intervention
Patricia Holch, PhD,*,y Kate L. Absolom, PhD,y,z Ann M. Henry, MD,y,x Katrina Walker, MSc,â•‘,1 Andrea Gibson, RN,y,x Eleanor Hudson, MSc,â•‘ Zoe Rogers, MSc,y Marie Holmes, MSc,y Rosemary Peacock, PhD,y Simon Pini, PhD,z Alexandra Gilbert, PhD,y,x,â•‘ Susan Davidson, MD,{ Jacqueline Routledge, RN,{ Anthony Murphy, RN,{ Kevin Franks, MD,x Claire Hulme, PhD,# Jenny Hewison, PhD,z Carolyn Morris, BSc,y Lucy McParland, MSc,** Julia Brown, MSc,â•‘,2 and Galina Velikova, PhDy
doi : 10.1016/j.ijrobp.2022.09.078
Volume 115, Issue 3, 1 March 2023, Pages 664-676
Phase 1 Study of the Combination of Escalated Total Marrow Irradiation Using Helical Tomotherapy and Fixed High-Dose Melphalan (140 mg/m²) Followed by Autologous Stem Cell Transplantation at First Relapse in Multiple Myeloma
Axel Cailleteau, MD,* Philippe Maingon, MD, PhD,y Sylvain Choquet, MD,z Remi Bourdais, MD,y Delphine Antoni, MD, PhD,x Bruno Lioure, MD,â•‘ Cyrille Hulin, MD,{ Stephanie Batard, MD, # Camille Llagostera, MS,** Valentine Guimas, MD,* Cyrille Touzeau, MD, PhD,yy,xx,â•‘â•‘ Philippe Moreau, MD, PhD,yy,xx,â•‘â•‘ Marc-Andre Mahe, MD, PhD,zz and Stephane Supiot, MD, PhD*,
doi : 10.1016/j.ijrobp.2022.09.069
Volume 115, Issue 3, 1 March 2023, Pages 677-685
Dose-Escalated 2-Fraction Spine Stereotactic Body Radiation Therapy: 28 Gy Versus 24 Gy in 2 Daily Fractions
K. Liang Zeng, MD,* Ahmed Abugarib, MD,*,y Hany Soliman, MD,* Sten Myrehaug, MD,* Zain A. Husain, MD,* Jay Detsky, MD, PhD,* Mark Ruschin, PhD,* Aliaksandr Karotki, PhD,* Eshetu G. Atenafu, MSc,z Jeremie Larouche, MD,x Mikki Campbell, BSc,* Pejman Maralani, MD,â•‘ Arjun Sahgal, MD,* and Chia-Lin Tseng, MDCM*
doi : 10.1016/j.ijrobp.2022.09.076
Volume 115, Issue 3, 1 March 2023, Pages 686-695
Parameters of the Lyman Model for Calculation of Normal-Tissue Complication Probability: A Systematic Literature Review
Fabio Dennst€adt, MD,* Michaela Medova, PhD,y,z Paul Martin Putora, MD, PhD,* ,y and Markus Glatzer, MD*
doi : 10.1016/j.ijrobp.2022.08.039
Volume 115, Issue 3, 1 March 2023, Pages 696-706
Diffusing Alpha-Emitters Radiation Therapy Promotes a Proimmunogenic Tumor Microenvironment and Synergizes With Programmed Cell Death Protein 1 Blockade
Sara Del Mare, PhD,* Yossi Nishri, PhD,* Amit Shai, MSc,* Margalit Efrati, MSc,* Lisa Deutsch, PhD,y Robert B. Den, MD,*,z Itzhak Kelson, PhD,x Yona Keisari, PhD,â•‘ and Vered Domankevich, PhD*
doi : 10.1016/j.ijrobp.2022.08.043
Volume 115, Issue 3, 1 March 2023, Pages 707-718
Lenvatinib Synergistically Promotes Radiation Therapy in Hepatocellular Carcinoma by Inhibiting Src/STAT3/NF-κB-Mediated Epithelial–Mesenchymal Transition and Metastasis
Yueh-Shan Weng,*,1 I-Tsang Chiang,y,z,x,â•‘,1 Jai-Jen Tsai,{,#,**,1 Yu-Chang Liu,y,x,yy and Fei-Ting Hsu,*
doi : 10.1016/j.ijrobp.2022.09.060
Volume 115, Issue 3, 1 March 2023, Pages 719-732
Radiation Therapy Exacerbates Tumor-Promoting Innervation and Nerve Signaling in Rectal Cancer
Taylor P. Uccello, PhD,* Maggie L. Lesch, BS,* Nicholas A. Ullman, MD,y Sarah A. Kintzel, BS,z Lauren B. Gradzewicz,* Trishna Velagaleti,y Fergal J. Fleming, MD,y Bradley N. Mills, PhD,y Joseph D. Murphy, PhD,* Jesse Garrett-Larsen, BS,y Haoming Qiu, MD,x Michael G. Drage, MD,â•‘ Jian Ye, PhD,y Nicholas W. Gavras, BS,y Carl J. Johnston, PhD,{ Tanzy M.T. Love, PhD,# Elizabeth A. Repasky, PhD,** David C. Linehan, MD,y Edith M. Lord, PhD,* and Scott A. Gerber, PhD*,
doi : 10.1016/j.ijrobp.2022.09.080
Volume 115, Issue 3, 1 March 2023, Pages 733-745
Radiomics and Dosiomics Signature From Whole Lung Predicts Radiation Pneumonitis: A Model Development Study With Prospective External Validation and Decision-curve Analysis
Zhen Zhang, PhD,* ,y Zhixiang Wang, PhD,y Meng Yan, MD,* Jiaqi Yu, MD,* Andre Dekker, PhD,y Lujun Zhao, PhD, MD,* and Leonard Wee, PhD
doi : 10.1016/j.ijrobp.2022.08.047
Volume 115, Issue 3, 1 March 2023, Pages 746-758
Pencil-beam Delivery Pattern Optimization Increases Dose Rate for Stereotactic FLASH Proton Therapy
Rodrigo Jose Santo, MSc,* ,y,z Steven J.M. Habraken, PhD,*,z Sebastiaan Breedveld, PhD,* and Mischa S. Hoogeman, PhD
doi : 10.1016/j.ijrobp.2022.08.053
Volume 115, Issue 3, 1 March 2023, Pages 759-767
TVL1-IMPT: Optimization of Peak-to-Valley Dose Ratio Via Joint Total-Variation and L1 Dose Regularization for Spatially Fractionated Pencil-Beam-Scanning Proton Therapy
Weijie Zhang, PhD, Wangyao Li, PhD, Yuting Lin, PhD, Fen Wang, MD, Ronald C. Chen, MD, and Hao Gao, PhD
doi : 10.1016/j.ijrobp.2022.09.064
Volume 115, Issue 3, 1 March 2023, Pages 768-778
A Deep Learning-Based Computer Aided Detection (CAD) System for Difficult-to-Detect Brain Metastases
Andrew T. Fairchild, MD,* ,y Joseph K. Salama, MD,*,z Walter F. Wiggins, MD, PhD,x Bradley G. Ackerson, MD,* Peter E. Fecci, MD, PhD,â•‘ John P. Kirkpatrick, MD, PhD,*,â•‘ Scott R. Floyd, MD, PhD,* and Devon J. Godfrey, PhD
doi : 10.1016/j.ijrobp.2022.09.068
Volume 115, Issue 3, 1 March 2023, Pages 779-793
The Effect of Stereotactic Body Radiation Therapy for Hepatocellular Cancer on Regional Hepatic Liver Function
Lise Wei, PhD,* Josiah Simeth, PhD,y Madhava P. Aryal, PhD,* Martha Matuszak,* Randall K. Ten Haken, PhD,* Kyle Cuneo, MD, PhD,* Theodore S. Lawrence, MD, PhD,* and Yue Cao, PhD
doi : 10.1016/j.ijrobp.2022.09.077
Volume 115, Issue 3, 1 March 2023, Pages 794-802
Predicting Treatment Response From Extracellular Volume Fraction for Chemoradiation Therapy of Pancreatic Cancer
George Noid, PhD,* Garrett Godfrey, PhD,* William Hall, MD,* Jainil Shah, PhD,y Eric Paulson, PhD,* Paul Knechtges, MD,z Beth Erickson, MD,* and X. Allen Li, PhD
doi : 10.1016/j.ijrobp.2022.09.084
Volume 115, Issue 3, 1 March 2023, Pages 803-808
In Regard to Trofimov et al
Aysenur Elmali, MDGozde Yazici, MD
doi : 10.1016/j.ijrobp.2022.10.021
Volume 115, Issue 3, 1 March 2023, Pages 809-810
In Reply to Elmali and Yazici
Alexei V. Trofimov, PhDMary E. Aronow, MDMarc R. Bussiere, MScEvangelos S. Gragoudas, MDFlorence K. Keane, MDIvana K. Kim, MDHelen A. Shih, MDMandar S. Bhagwat, PhD
doi : 10.1016/j.ijrobp.2022.10.020
Volume 115, Issue 3, 1 March 2023, Pages 810-811
