Aging




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Isoaspartate and neurodegeneration

Jijing Wang, Sourav Mukherjee, Roman A. Zubarev

doi : 10.18632/aging.204420

Volume 14, Issue 22

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Racial and ethnic disparities in Alzheimer’s dementia

Unhee Lim, Song-Yi Park

doi : 10.18632/aging.204421

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Phosphoglycerate kinase 1 protects against ischemic damage in the gerbil hippocampus

Kyu Ri Hahn, Hyun Jung Kwon, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang

doi : 10.18632/aging.204343

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Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice

Matthew Triolo, Debasmita Bhattacharya, David A. Hood

doi : 10.18632/aging.204365

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Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model

Kento Takaya, Tatsuyuki Ishii, Toru Asou, Kazuo Kishi

doi : 10.18632/aging.204391

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The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study

Takehiko Yamanashi, Zoe-Ella EM Anderson, Manisha Modukuri, Gloria Chang, Tammy Tran, Pedro S. Marra, Nadia E. Wahba, Kaitlyn J. Crutchley, Eleanor J. Sullivan, Sydney S. Jellison, Katie R. Comp, Cade C. Akers, Alissa A. Meyer, Sangil Lee, Masaaki Iwata, Hyunkeun R. Cho, Eri Shinozaki, Gen Shinozaki

doi : 10.18632/aging.204393

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JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models

Geun-Hyoung Ha, Eun Ji Kim, Jee Soo Park, Ji Eun Kim, Hyun Nam, Je Young Yeon, Sun-Ho Lee, Kyunghoon Lee, Chung Kwon Kim, Kyeung Min Joo

doi : 10.18632/aging.204410

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Antrodia Camphorata Polysaccharide activates autophagy and regulates NLRP3 degradation to improve liver injury-related inflammatory response

Shuiliang Ruan, Yi Yang, Wenyan Li

doi : 10.18632/aging.204330

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Protective effect of total saponins of ginseng stems and leaves (GSLS) on chlorpyrifos-induced brain toxicity in mice through the PTEN/PI3K/AKT axis

Hong Wu, Hongyan Pei, Jinze Liu, Jianning Zeng, Silu Liu, Weijia Chen, Zhongmei He, Rui Du

doi : 10.18632/aging.204374

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NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway

Rui Zhao, Yuzhen Ge, Yongjun Gong, Bo Li, Benli Xiao, Shi Zuo

doi : 10.18632/aging.204377

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Molecular subtypes identified by pyroptosis-related genes are associated with tumor microenvironment cell infiltration in colon cancer

Yiting Ling, Yinda Wang, Chenxi Cao, Lianzhong Feng, Binzhong Zhang, Senjuan Li

doi : 10.18632/aging.204379

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Development and validation of a novel model for predicting the survival of bladder cancer based on ferroptosis-related genes

Lianjun Li, Leizuo Zhao, Bin Li, Tengteng Wang, Weiting Kang, Zilian Cui, Dongjian Liu, Da Gu

doi : 10.18632/aging.204385

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Circadian rhythm-related factors of PER and CRY family genes function as novel therapeutic targets and prognostic biomarkers in lung adenocarcinoma

Chin-Chou Wang, Wei-Hsun Lin, Su-Chi Ku, Wan-Jou Shen, Hoang Dang Khoa Ta, Gangga Anuraga, Fang-Wen Liu, Chiu-Fan Shen, Shu-He Wang, Chia-Chen Yang, Chih-Yang Wang, Wei-Jan Wang

doi : 10.18632/aging.204386

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A novel risk score model based on four angiogenesis long non-coding RNAs for prognosis evaluation of pancreatic adenocarcinoma

Guangbiao Cao, Yihang Chang, Guang Yang, Yong Jiang, Keqiang Han

doi : 10.18632/aging.204387

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Exploring the mechanisms underlying the therapeutic effect of the Radix Bupleuri-Rhizoma Cyperi herb pair on hepatocellular carcinoma using multilevel data integration and molecular docking

Luzhi Qing, Botao Pan, Yanjun He, Yu Liu, Minhong Zhao, Bo Niu, Xiuan Gao

doi : 10.18632/aging.204388

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Prognostic value and immunological role of FOXM1 in human solid tumors

Guohua Wei, Xin Yang, Huangzhou Lu, Lan Zhang, Yong Wei, Hai Li, Mingxia Zhu, Xin Zhou

doi : 10.18632/aging.204394

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LINC00629, a KLF10-responsive lncRNA, promotes the anticancer effects of apigenin by decreasing Mcl1 stability in oral squamous cell carcinoma

Chun Shi, Changhong Ma, Chunmei Ren, Na Li, Xiaotong Liu, Yahan Zhang, Yulong Wang, Xiaodong Li, Peng Lv, Chuanchun Han, Xiaojie Li

doi : 10.18632/aging.204396

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Minichromosome maintenance gene family: potential therapeutic targets and prognostic biomarkers for lung squamous cell carcinoma

Xuejie Yang, Chunrong Wang, Hui Nie, Jianhua Zhou, Xiaoyun He, Chunlin Ou

doi : 10.18632/aging.204399

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Restraint stress of female mice during oocyte development facilitates oocyte postovulatory aging

Ren-Ren Chen, Jia Wang, Min Zhang, Qiao-Qiao Kong, Guang-Yi Sun, Chun-Hui Jin, Ming-Jiu Luo, Jing-He Tan

doi : 10.18632/aging.204400

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Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humans

Qiyu Yang, Juan Hu, Meng Wang, Na Guo, Liu Yang, Qingsong Xi, Lixia Zhu, Lei Jin

doi : 10.18632/aging.204401

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Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers

Mingzhou Gao, Hao Zhang, Zhan Gao, Ya Sun, Guanghao Xu, Fengqin Wei, Jieqiong Wang, Dongmei Gao

doi : 10.18632/aging.204402

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Comprehensive analysis of the expression profile and clinical implications of regulator of chromosome condensation 2 in pan-cancers

Xuanxuan Li, Kuo Kang, Yuanhao Peng, Lin Shen, Liangfang Shen, Yangying Zhou

doi : 10.18632/aging.204403

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System analysis based on the ER stress-related genes identifies WFS1 as a novel therapy target for colon cancer

Xianguang Yang, Chaoyang Zhang, Cheng Yan, Liukai Ma, Jiahao Ma, Xiaoke Meng

doi : 10.18632/aging.204404

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CD229 interacts with RASAL3 to activate RAS/ERK pathway in multiple myeloma proliferation

Zigen Lin, Xiaozhu Tang, Yuhao Cao, Lijin Yang, Mingmei Jiang, Xinying Li, Jie Min, Bing Chen, Ye Yang, Chunyan Gu

doi : 10.18632/aging.204405

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The circRNA expression profile of colorectal inflammatory cancer transformation revealed potential predictive biomarkers

Lu Lu, Yujing Liu, Guangtao Zhang, Yangxian Xu, Dan Hu, Guang Ji, Hanchen Xu

doi : 10.18632/aging.204406

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The roles of CPSF6 in proliferation, apoptosis and tumorigenicity of lung adenocarcinoma

Yukun Zu, Dao Wang, Wei Ping, Wei Sun

doi : 10.18632/aging.204407

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High SURF4 expression is associated with poor prognosis of breast cancer

Jingtong Zhai, Jiashu Han, Cong Li, Fengzhu Guo, Fei Ma, Binghe Xu

doi : 10.18632/aging.204409

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Organotypic cultures as aging associated disease models

Martina M. Sanchez, Isabella A. Bagdasarian, William Darch, Joshua T. Morgan

doi : 10.18632/aging.204361

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