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For-Profit Medical Schools — Concerns about Quality and Oversight
Robert Shireman, M.Ed., M.P.A.
doi : 10.1056/NEJMp2117605
Vol. 387 No. 23
Closing the Gap in Cancer Genomic Testing
Richard L. Schilsky, M.D., and Dan L. Longo, M.D.
doi : 10.1056/NEJMp2210638
Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma
Maartje W. Rohaan, M.D., Troels H. Borch, M.D, Ph.D., Joost H. van den Berg, Ph.D., Özcan Met, Ph.D., Rob Kessels, Ph.D., Marnix H. Geukes Foppen, M.D., Ph.D., Joachim Stoltenborg Granhøj, M.D., Bastiaan Nuijen, Ph.D., Cynthia Nijenhuis, Ph.D., Inge Jedema, Ph.D., Maaike van Zon, BSc, Saskia Scheij, BSc,
doi : 10.1056/NEJMoa2210233
Immune checkpoint inhibitors and targeted therapies have dramatically improved outcomes in patients with advanced melanoma, but approximately half these patients will not have a durable benefit. Phase 1–2 trials of adoptive cell therapy with tumor-infiltrating lymphocytes (TILs) have shown promising responses, but data from phase 3 trials are lacking to determine the role of TILs in treating advanced melanoma.
Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only
Jonas Hugosson, M.D., Ph.D., Marianne Månsson, Ph.D., Jonas Wallström, M.D., Ph.D., Ulrika Axcrona, M.D., Ph.D., Sigrid V. Carlsson, M.D, Ph.D., M.P.H., Lars Egevad, M.D., Ph.D., Kjell Geterud, M.D., Ph.D., Ali Khatami, M.D., Ph.D., Kimia Kohestani, M.D., Ph.D., Carl-Gustaf Pihl, M.D., Andreas Socratous, M.D., Johan Stranne, M.D., Ph.D.,
doi : 10.1056/NEJMoa2209454
Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial
Kevin D. Hill, M.D., M.S.C.I., Prince J. Kannankeril, M.D., M.S.C.I., Jeffrey P. Jacobs, M.D., H. Scott Baldwin, M.D., Marshall L. Jacobs, M.D., Sean M. O’Brien, Ph.D., David P. Bichel, M.D., Eric M. Graham, M.D., Brian Blasiole, M.D., Ph.D., Ashraf Resheidat, M.D., Adil S. Husain, M.D., S. Ram Kumar, M.D., Ph.D.,
doi : 10.1056/NEJMoa2212667
Although perioperative prophylactic glucocorticoids have been used for decades, whether they improve outcomes in infants after heart surgery with cardiopulmonary bypass is unknown.
In Utero Enzyme-Replacement Therapy for Infantile-Onset Pompe’s Disease
Jennifer L. Cohen, M.D., Pranesh Chakraborty, M.D., Karen Fung-Kee-Fung, M.D., Marisa E. Schwab, M.D., Deeksha Bali, Ph.D., Sarah P. Young, Ph.D., Michael H. Gelb, Ph.D., Hamid Khaledi, Ph.D., Alicia DiBattista, Ph.D., Stacey Smallshaw, R.N., Felipe Moretti, M.D., Derek Wong, M.D.,
doi : 10.1056/NEJMoa2200587
Filarial Dance Sign in Lymphatic Filariasis of the Scrotum
Amit K. Sahu, M.B., B.S., D.N.B., and Bharat Aggarwal, M.B., B.S., M.D.
doi : 10.1056/NEJMicm2022348
Case 37-2022: A 55-Year-Old Man with Fatigue, Weight Loss, and Pulmonary Nodules
Matthew B. Roberts, M.B., B.S., Jarone Lee, M.D., M.P.H., Mark C. Murphy, M.D., Arthur Y. Kim, M.D., Erin E. Coglianese, M.D., and Caroline Hilburn, M.D.
doi : 10.1056/NEJMcpc2211357
Audio Interview: Covid-19 and Health Equity
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., Matifadza Hlatshwayo Davis, M.D., M.P.H., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2215782
