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COVID-19 and cutaneous manifestations: A review of the published literature
Fabrizio Martora MD, Alessia Villani MD, Gabriella Fabbrocini PROF-MD, Teresa Battista MD
doi : 10.1111/jocd.15477
COVID-19 is a highly contagious respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2. COVID-19 outbreak, which caused thousands of deaths, has been declared a pandemic by the World Health Organization in March 2020.
COVID-19 and artificial intelligence: Experts and dermatologists perspective
Yaser Goldust PhD, Farah Sameem MD, Samia Mearaj MD, Atula Gupta MD, Anant Patil MD, Mohamad Goldust MD
doi : 10.1111/jocd.15310
Artificial intelligence (AI) has an important role to play in future healthcare offerings. Machine learning and artificial neural networks are subsets of AI that refer to the incorporation of human intelligence into computers to think and behave like humans.
Body care activities and its consequences related to COVID-19 pandemic
Patrycja Mościcka MSc
doi : 10.1111/jocd.15314
Symptoms of illnesses related to COVID-19 disease include also dermatological changes. Moreover, modification of cosmetic and hygenic habits are widely noted.
Dermatological impact of hand hygiene practices during COVID-19: A cross-sectional web-based survey among doctors in a tertiary care hospital in Eastern India
Gaurav Dash MD, Nibedita Patro MD, Binayak Chandra Dwari MD, Kumar Abhishek MD
doi : 10.1111/jocd.15508
The COVID-19 pandemic continues to persist throughout the world with intermittent exacerbation. The changing trend of hand hygiene practices during this pandemic has led to new onset or aggravation of pre-existing hand eczema, especially among doctors. There is a paucity of studies regarding skin changes seen with changing hand hygiene practices in the Indian subcontinent.
Safely use of omalizumab during SARS-CoV-2 infection in patients with chronic spontaneous urticaria
Öner Özdemir MD, Ãœmmügülsüm Dikici MD
doi : 10.1111/jocd.15544
Cutaneous reactions following COVID-19 vaccination: The evidence says “less fear�
Luca Potestio MD, Gabriella Fabbrocini MD, Michela D'Agostino MD, Ilaria Piscitelli MD, Fabrizio Martora MD
doi : 10.1111/jocd.15533
Pemphigus vulgaris and COVID-19 vaccination: Management and treatment
Fabrizio Martora MD, Teresa Battista MD, Paola Nappa MD, Gabriella Fabbrocini PROF-MD, Matteo Megna MD
doi : 10.1111/jocd.15374
COVID-19 vaccination and inflammatory skin diseases
Fabrizio Martora MD, Alessia Villani MD, Teresa Battista MD, Gabriella Fabbrocini MD, Luca Potestio MD
doi : 10.1111/jocd.15414
Can mRNA COVID-19 vaccines induce flares of chronic urticaria?
Silada Kanokrungsee MD, Chananchida Naruenatwanich MD
doi : 10.1111/jocd.15443
Herpes zoster and alopecia areata following mRNA BNT162b2 COVID-19 vaccine: Controversial immune effects
Fabrizio Martora MD, Luigi Fornaro MD, Vincenzo Picone MD, Dario Marasca MD, Maurizio Gargiulo MD, Maria Carmela Annunziata MD, Gabriella Fabbrocini PROF-MD, Claudio Marasca MD
doi : 10.1111/jocd.15465
Letter to the editor regarding article “Hlaca N, Zagar T, Kastelan M, Peternel S, Brajac I, Prpic-Massari L. New-onset lichen planus and lichen planus flare in elderly women after COVID-19 vaccination. J Cosmet Dermatol. 2022;10.1111/jocd.15185�
Luca Potestio MD, Alessia Villani MD, Gabriella Fabbrocini MD, Fabrizio Martora MD
doi : 10.1111/jocd.15491
Erosive pustular dermatosis of the scalp in the COVID-19 era
Nesrine Ben Salah MD, Amina Aounallah MD, Lella Douh MD, Khaoula Trimeche MD, Badreddine Sriha PhD, Mohamed Denguesli PhD
doi : 10.1111/jocd.15495
Expert consensus on holistic skin care routine: Focus on acne, rosacea, atopic dermatitis, and sensitive skin syndrome
Chee-Leok Goh MD, MBBS, MRCP(UK), MMed(Int Med), FACD(Hon), Yan Wu MD, PhD, Belinda Welsh MBBS, MMed, FACD, Ma Flordeliz Abad-Casintahan MD, FPDS, Chung-Jen Tseng MD, Jaishree Sharad MBBS, DDV, IFAAD, SungKyu Jung MD, MS, Jinda Rojanamatin MD, Irma Bernadette S. Sitohang MD, PhD, Hau Ngai Kingsley Chan MBBS (HK), MRCP (UK), Dip Derm (Glas), FHKCP, FHKAM (Medicine), FRCP (Glasg), FRCP (Edin)
doi : 10.1111/jocd.15519
Treatment, cleansing, moisturizing, and photoprotection are four major components of holistic skin care for dermatological conditions. While treatment (T) is recognized as a key component in the management of dermatological conditions, there is a lack of practical guidance on the adjunctive role of cleansing, moisturizing, and photoprotection (“CMP�).
Treatment of bruising after injection to reduce cellulite
Michael H. Gold MD
doi : 10.1111/jocd.15471
Cellulite 80%–98% of post-pubertal women and results in cutaneous dimples in the affected area.
Biologic and targeted therapeutics in vitiligo
Priyanka Karagaiah MD, Robert A. Schwartz MD, Torello Lotti MD, Uwe Wollina MD, Stephan Grabbe MD, Mohamad Goldust MD
doi : 10.1111/jocd.14770
Vitiligo is a long-standing progressive autoimmune disease with depigmented macules/patches with significant psychological morbidity to the patients. From being one of the most poorly understood diseases in the past, there has been a rampant advance in determining the molecular and genetic factors influencing the disease process.
Non-laser treatment for tattoo removal
Gaurav Dash MD, Anant Patil MD, Martin Kassir MD, Mitchel P. Goldman MD, Michael H. Gold MD, Maurice Adatto MD, Stephan Große-Büning MD, Stephan Grabbe MD, Mohamad Goldust MD
doi : 10.1111/jocd.14819
Tattoos are increasingly gathering attention in the young population, especially in second to fourth decade of life. With such trends, rate of its removal also has been on the rise.
In search of the perfect tan: Chemical activity, biological effects, business considerations, and consumer implications of dihydroxyacetone sunless tanning products
Josh Turner MChem, PhD, Danielle A. O’Loughlin MEng, PhD, Phill Green BSc, Tom O. McDonald BSc, MSc, PhD, Kevin J. Hamill BSc, PhD
doi : 10.1111/jocd.14968
As the desire and popularity of a tanned appearance continues, the social effects of UV-free tanning are becoming more important. Dihydroxyacetone (DHA) has seen extensive use as the main tanning agent in sunless tanners. The DHA-induced tan is a result of brown melanoidins formed by a non-enzymatic Maillard reaction between DHA and amino acid species found in the stratum corneum.
The psychological consequences of androgenetic alopecia: A systematic review
Erica L. Aukerman BS, Mohammad Jafferany MD
doi : 10.1111/jocd.14983
Androgenetic alopecia is the most common cause of hair loss in both males and females. In a society that places significant value on hair and associates it with attractiveness, a lack there of can have damaging psychological consequences.
Review of the microbiome in skin aging and the effect of a topical prebiotic containing thermal spring water
Heather Woolery-Lloyd MD, FAAD, Anneke Andriessen PhD, Doris Day MD, Noelani Gonzalez MD, Lawrence Green MD, Elizabeth Grice PhD, Michelle Henry MD, FAAD
doi : 10.1111/jocd.15464
Interest in the skin microbiome and the cosmetic benefits of probiotics, prebiotics, and postbiotics is increasing.
Benefits and safety of Oxymetazoline cream 1% on rosacea-associated erythema: A systematic review and analysis of clinical evidence
Xin Yuan MD, Dan Yin MD
doi : 10.1111/jocd.15467
Facial persistent erythema is recognized as difficult feature to treat in rosacea. Topical Oxymetazoline cream 1% has been used to treat persistent facial erythema in rosacea patients for some years.
Cosmetic gynecology�An emerging field for the dermatologist
Anuradha Jindal MBBS, MD, FRGUHS, Venkataram Mysore MBBS, DVD, MD, DNB, DipRCPath, FRCP, FISHRS, Jayashree Venkataram Mysore MBBS, FRCOG
doi : 10.1111/jocd.15484
Cosmetic gynecology is an expanding field with a steep rise in awareness and demand for procedures to enhance the aesthetic appearance of female genitalia.
Clinical outcomes after lip injection procedures�Comparison of two hyaluronic acid gel fillers with different product properties
Said Hilton MD, Konstantin Frank MD, Michael Alfertshofer MD, Sebastian Cotofana MD, PhD
doi : 10.1111/jocd.15548
Transient swelling is common after lip injections with hyaluronic acid (HA) based fillers. Swelling and other injection-site reactions may relate to the injection procedure itself, or to gel properties, which differ between fillers due to differences in manufacturing methods.
Botulinum toxin for cosmetic treatments in young adults: An evidence-based review and survey on current practice among aesthetic practitioners
Alain Michon MD, MSc, CCFP-EM
doi : 10.1111/jocd.15513
Botulinum toxin A (BoNTA) treatments are popular worldwide. Young adults, less than 41 years of age, are an important cohort of patients seen in practice, and the optimal dosage of BoNTA in this age group remains poorly defined.
Eyebrow lifting with barbed threads: A simple, safe, and effective ambulatory procedure
Adriano Santorelli MD, Pierfrancesco Cirillo MD, Salvatore Piero Fundarò MD, Maurizio Cavallini MD, Giovanni Salti MD, Stefano Avvedimento MD
doi : 10.1111/jocd.15006
Changes in brow positioning are one of the first facial aging signs. A more beautiful and younger look can be achieved by repositioning the tissues involved in brow descent and sagging eyelids.
Clinical efficacy and safety of polynucleotides highly purified technology (PN-HPT®) and cross-linked hyaluronic acid for moderate to severe nasolabial folds: A prospective, randomized, exploratory study
Antonino Araco MD, Francesco Araco MD, PhD, Mauro Raichi MD
doi : 10.1111/jocd.15064
The mandibular profile undergoes progressive wasting with aging, and the deepening of nasolabial folds (NLFs) has a leading role. Hyaluronic acid (HA) efficiently controls tissue hydration and permeability to small and large molecules.
Effect of a hyaluronic acid-based mesotherapeutic injectable on the gene expression of CLOCK and Klotho proteins, and environmentally induced oxidative stress in human skin cells
Aleksei Prokopov MD, PhD, Anna Drobintseva PhD, Igor Kvetnoy MD, Zarema Gazitaeva MD, Anna Sidorina MD
doi : 10.1111/jocd.15078
Normal circadian rhythms are essential to the repair mechanisms of oxidative stress implicated in skin aging. Given reports that hyaluronic acid (HA) homeostasis exhibits a different profile in chronological skin aging, as compared to environmental or extrinsic aging, an improved understanding of the way HA interacts with its surroundings, and the impact of HA injectables in replacing lost HA and encouraging rejuvenation, is of key benefit to skin aging treatments. The objectives of these current studies were twofold.
Filler injections in the pre-auricular space: Be aware of the parotid gland
Leonie Schelke MD, PhD, Tamar Schoonen BSc, Peter J. Velthuis MD, PhD, BSc
doi : 10.1111/jocd.15319
In recent years the pre-auricular area is increasingly used for filler injections.
Real-world effectiveness and safety of collagenase clostridium histolyticum-aaes injections for the treatment of thigh cellulite in women: An open-label study interim analysis
John H. Joseph MD, Steven H. Dayan MD, Ashish C. Bhatia MD, Sabrina G. Fabi MD, Sachin M. Shridharani MD, Lisa Donofrio MD, Jose R. Montes MD, Melanie D. Palm MD, MBA, Genzhou Liu PhD, David Hernandez MD, Jill Edgecombe BS, Saji Vijayan MBBS, Deanne Mraz Robinson MD
doi : 10.1111/jocd.15451
Collagenase clostridium histolyticum-aaes (CCH-aaes) is approved in the United States for moderate-to-severe cellulite in the buttocks of adult women.
Locking the line of convergence by botulinum toxin type A for the treatment of dynamic forehead wrinkles
Yehia F. El-Garem MD, Amira Abulfotooh Eid MD, Tahra M. Leheta MD
doi : 10.1111/jocd.15468
Treatment of horizontal forehead lines with botulium toxin type A is a common procedure that helps achieve a youthful and rejuvenated look. Adequate knowledge of the anatomy and an individualized treatment approach is the key to successful treatment outcome.
Concomitant use of radiofrequency and high intensity focused electromagnetic field energies for full-body remodeling: MRI evidence-based prefatory trial
Bruce Katz MD
doi : 10.1111/jocd.14736
Radiofrequency and HIFEM have been used as standalone modalities in body contouring. The novel device allows their synchronous emission simultaneously in a single applicator.
Effectiveness of combined use of targeted pressure energy, radiofrequency, and high-intensity focused electromagnetic fields to improve skin quality and appearance of fat and muscle tissue in different body parts
Diane Irvine Duncan MD, FACS, Mariano Busso MD
doi : 10.1111/jocd.15280
Inevitable signs of aging are especially noticeable in middle to elder age when stretch marks, loose skin, cellulite, and body-contour changes naturally appear.
Efficacy and tolerability of a microneedling device for treating wrinkles on the face
Mona Alqam MD, Christine E. Wamsley BA, Thomas M. Hitchcock PhD, Brian C. Jones PhD, Yucel Akgul MD, PhD, Jeffrey M. Kenkel MD, FACS
doi : 10.1111/jocd.14985
A microneedling pen has been cleared by the US Food and Drug Administration, indicated for improving the appearance of adult facial acne scars. The objective of this study was to assess the device's effectiveness for treating wrinkles of the face area.
Clinical evaluation of the efficacy of fractional radiofrequency for the treatment and reduction of stretch marks: AÂ prospective study
Maurice Adatto MD
doi : 10.1111/jocd.15463
Skin resurfacing with fractional radiofrequency results in reepithelization, collagen shrinkage, fibroblast stimulation, and neocollagenesis which may be beneficial for the improvement of various skin lesions. This clinical study was conducted to evaluate the safety and efficacy of fractional radiofrequency device (FRF) for the treatment of striae.
The growing importance of ultrasonography in cosmetic dermatology: An update after the 23rd IMCAS Annual World Congress (2022)
Diala Haykal MD, Hugues Cartier MD, Michael Benzaquen MD, Giovanni Damiani MD, Sayed Meelad Habib MD, PhD
doi : 10.1111/jocd.15503
Ultrasound (US) has been used for many years in the field of medicine. Many specialties have embraced US as a quick, painless, and relatively inexpensive tool to assist the clinician in determining anatomy, pathology, and aid in diagnostic or therapeutic procedures.
A Rejuvenating treatment targeting “tech neck� lines and wrinkles in Chinese women: A prospective, open-label, single-center study
Morgann B. Young MS, Wei Lai MD, Tatiana Kononov BS, MBA, Alisar S. Zahr PhD
doi : 10.1111/jocd.15497
Aging of neck and jawline skin is caused by intrinsic and extrinsic factors and is evidenced by wrinkling, laxity, skin dyspigmentation, loss of the mandibular contour, accumulation of submental fat, density loss, and prominent platysma bands.
Improvements in skin quality parameters in postmenopausal participants after use of topical growth factor serum
Michael H. Gold MD, April Wilson RN, BSN, Elizabeth Makino MBA, Rahul Mehta PhD
doi : 10.1111/jocd.15472
Photodamage can induce skin aging processes that can be particularly concerning for postmenopausal women. Growth factors from hypoxic human fibroblast-conditioned media have demonstrated improvements in skin quality parameters.
Protective effects of a day/night dual-antioxidant serum on skin: A randomized, regimen-controlled study in Chinese women exposed to air pollution
Wei Liu MD, Liyun Jie MM, Dan Liu MA Sc, MM, Elizabeth T. Makino BS, CCRA, MBA, Jean Krutmann MD, Rahul C. Mehta PhD
doi : 10.1111/jocd.14839
To assess the efficacy of the LUMIVIVE® System (LVS), a skincare system consisting of individual day and night serums, in Chinese women exposed to air pollution.
Effects of repeated use of a commercial topical lotion on subcutaneous fat thickness in resistance-trained male athletes
Jackson J Peos, Julian Ong
doi : 10.1111/jocd.14853
This study tested whether subcutaneous fat loss is enhanced via application of a popular topical fat loss lotion.
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Emmanuel Martin MS, Anson Zhang MS, Remo Campiche PhD
doi : 10.1111/jocd.14913
Scalp conditions such as flaky or oily scalp affect people across ethnicities and age groups. In addition to flaking, increased sebum secretion, itching, and compromised scalp barrier function were described.
Peptide-pro complex serum: Investigating effects on aged skin
Melissa Moy MS, Isabel Diaz BA, Ewelina Lesniak BA, Giorgiana Giancola PhD
doi : 10.1111/jocd.14992
Ex vivoand clinical tests have evaluated the efficacy of a topical facial serum containing a proprietary blend of neuropeptides, proteins, amino acids, and marine extracts on aged skin.
Determinants of the influence and experiences of cosmetic and aesthetics profiling on interpersonal relationships among Indian patients
Debraj Shome MD, FRCS (Glasgow), FACS, MBA, Vaibhav Kumar MDS, FRSPH, René R. W. J. Van Der Hulst MD, PhD, Darren I. Booi MD, PhD, Harshal Tandel BDS, Shiva Ram Male M. Optom, PGDCL&IPR, Rinky Kapoor MD
doi : 10.1111/jocd.15511
The notion of facial beauty is a fast-expanding field in many different disciplines. The determinants and the nature of inter-personal relationships remain a controversial issue.
The burden of gout in acne keloidalis nuchae�Insights from a population-based study
Eran Shavit MD, Arnon Cohen MD, PhD, Lilach Zoller MD, MHA, Erez Onn MD, MHA, Khalaf Kridin MD, PhD
doi : 10.1111/jocd.15476
The risk of gout amid patients with acne keloidalis nuchae (AKN) has not been investigated in the past.
Standards for aseptic techniques in medical aesthetic practices in the Benelux: Consensus recommendations
Samira Baharlou MD, Koenraad De Boulle MD, Ivar van Heijningen MD, Isabella Cervini MD, Peter Termohlen MD
doi : 10.1111/jocd.15077
While the demand for aesthetic procedures is rising, complications are rising alongside. Infection is a frequent complication, there is therefore an increased need for strict aseptic technique, particularly in procedures breaching the skin. The level of training of practitioners carrying out these procedures varies and there are no comprehensive guidelines on aseptic aesthetic practice in the Benelux region.
Exploring the quality of life of cosmetic users: A cross-sectional analysis from eight Arab countries in the Middle East
Ali Haider Mohammed MD, Bassam Abdul Rasool Hassan PhD, Abdulrasool M. Wayyes PhD, Haydar F. Al-Tukmagi PhD, Ali Blebil PhD, Juman Dujaili PhD, Muhammed Hassan Nasr PhD, Maguy Saffouh El Hajj PhD, Diana Malaeb PhD, Sara Abu Alhija MD, Elham Kateeb PhD, Ahmad Amro PhD, Dalal Al-Taweel PhD, Muna Arif Al Juma PhD, Omar Abdulwahid Al-Ani MD, Sinan Subhi Farhan PhD, Rula M. Darwish PhD, Ahmed Talib Al-Zaabi MPharm
doi : 10.1111/jocd.15085
The use of cosmetic products is growing in dominance in the Arab population, making it essential to measure its effects on users. The production of cosmetics has been largely driven by consumerism and a bid to keep abreast with the latest trends in the beauty industry with less attention on how the users' quality of life (QoL) is affected.
Relationship between α-genus human papillomavirus and non-genital seborrheic keratosis: Report of new cases and updated review
Tobias Nellessen, Rui Aoki MD, PhD, Claudia Kammerbauer, Benjamin M. Clanner-Engelshofen MD, Lars E. French MD, Markus Reinholz MD, PhD, FEBDV
doi : 10.1111/jocd.14759
Seborrheic keratoses (SK) are the most common acquired benign tumor that affects middle-aged or older adults with great cosmetic concern. Clinical and histopathological similarities of SK and common warts have been addressed by investigating the possible presence of human papillomavirus (HPV) DNA in SK.
Effect of A. polygama APEE (Actinidia polygama ethanol extract) or APWE (Actinidia polygama water extract) on wrinkle formation in UVB-irradiated hairless mice
Yu-jin Kim MS, Jung Ok Lee PhD, Su-Young Kim MS, Jung Min Lee MS, Esther Lee MS, Jungtae Na PhD, Kwang-Ho Yoo MD, Su-Jin Park PhD, Beom Joon Kim MD, PhD
doi : 10.1111/jocd.14925
Actinidia polygama (silver vine) is considered a medical plant which has been used in oriental medicine. It has been used for the treatment of pain, gout, rheumatoid arthritis, and inflammation. Few studies reported on the effect of Actinidia polygama (silver vine) on skin photoaging.
2-kDa hyaluronan ameliorates human facial wrinkles through increased dermal collagen density related to promotion of collagen remodeling
Yukina Abe, Satoshi Seino PhD, Hitoshi Kurihara, Madoka Kage PhD, Yoshihiro Tokudome PhD
doi : 10.1111/jocd.15097
Hyaluronan (HA) oligosaccharides are involved in several biological processes, primarily collagen remodeling and wound healing. Collagen remodeling is retarded in aging skin and causes wrinkles. The aim of this study was to evaluate the effect of 2-kDa HA oligosaccharides (HA2k) on wrinkles by permeation through the stratum corneum and promotion of collagen remodeling.
Anti-wrinkle properties of Angelica gigas Nakai root extracts using mineral-rich water
Jung-Wook Kang MS, Hang-Eui Cho PhD, Ho-Min Choi BS, In-Chul Lee PhD
doi : 10.1111/jocd.15017
Angelica gigas Nakai is used as an herbal pharmaceutical material in Korea.
Unilateral rosacea, unilateral demodicidosis, unitaleral Demodex sp. folliculitis: Three names for the same disease
Stefano Veraldi MD, PhD, Armando Pisapia MD, Gianluca Nazzaro MD, Vinicio Boneschi MD
doi : 10.1111/jocd.14863
Uncovering the roots of skin bleaching: Colorism and its detrimental effects
Karishma Daftary BA, Neha S. Krishnam BS, Roopal V. Kundu MD
doi : 10.1111/jocd.15049
