Journal of Herbal Medicine




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Phytochemical standardization of Eucalyptus tereticornis Smith (Myrtaceae) used in Green Pharmacy from Northeastern Brazil

Marina Arruda de Castro a,1, Igor Lima Soares b,2, Patrícia Georgina Garcia do Nascimento c,3, Karla do Nascimento Magalh ̃aes c,4, Ronald Targino Nojosa d,5, Said Gonçalves da Cruz Fonseca e,6, Sikiru Olaitan Balogun f,g,*,7, Mary Anne

doi : 10.1016/j.hermed.2022.100590

Volume 36, December 2022, 100590

Eucalyptus tereticornis Smith. is used in the Green Pharmacies Project in the state of Ceará, Brazil, for the treatment of respiratory ailments. Its major essential oil content is 1,8-cineole.

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Effects of saffron supplementation on serum inflammatory markers and quality of life in patients with ulcerative colitis: A double blind randomized controlled clinical trial

Azadeh Heydarian a, Amir Hossein Faghihi Kashani b, Mohsen Masoodi b, Naheed Aryaeian a,*, Mohammadreza Vafa a, Negin Tahvilian a, Agha Fatemeh Hosseini c, Soudabeh Fallah d, Nariman Moradi e, Farnaz Farsi

doi : 10.1016/j.hermed.2022.100593

Volume 36, December 2022, 100593

Ulcerative Colitis (UC) is accompanied by an increase in inflammation and oxidative stress. Saffron supplementation could improve inflammation status due to its anti-inflammatory and antioxidative effects. The aim of the present study was to investigate the effect of saffron tablets on serum concentration of inflammatory and anti-inflammatory markers and the quality of life in patients with UC.

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In Vitro hair growth and hair tanning activities of mangosteen pericarp extract on hair dermal papilla cells

Ying Fang Tan a, Yin Shin Koay a,c, Razauden Mohamed Zulkifli b, Mariani Abdul Hamid c

doi : 10.1016/j.hermed.2022.100594

Volume 36, December 2022, 100594

remature hair graying and hair loss in men and women can cause a serious aesthetic problem. However, not much effective treatment is available, especially from natural sources.

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The efficacy of the traditional Thai remedy “Ya-Ha-Rak� against dengue virus type 2

Wiyada Kwanhian Klangbud a,b,*, Jirarat Songsri a,b, Kingkan Bunluepuech c, Peechanika Chopjit

doi : 10.1016/j.hermed.2022.100595

Volume 36, December 2022, 100595

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Carob effects on antioxidant enzyme and elements level in infertile men: Secondary data analysis from a randomized controlled trial

Maryam Abolghasemi a,b, Mir Mohammad Reza Aghajani c, Faraz Mojab d, Neda Mahdinezhad Gorji c, Seyed Jafar Zakariayi c, Parvaneh Mirabi

doi : 10.1016/j.hermed.2022.100596

Volume 36, December 2022, 100596

Antioxidants play important roles in sperm quality. Carob (Ceratonia siliqua) is a natural source of antioxidants and it is used traditionally to improve the quality of semen. The current study aimed to evaluate the effect of carob syrup administration on the copper/zinc superoxide dismutase (Cu/Zn-SOD) activity and Zn and selenium (Se) levels in the serum of infertile men. Based on the authors knowledge, this is the first study on this topic.

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Prescription patterns of herbal medicines at a Brazilian Living Pharmacy: The Farmácia da Natureza experience, 2013–2019

Fabio Carmona a,c,*, Ana Maria Soares Pereira

doi : 10.1016/j.hermed.2022.100597

Volume 36, December 2022, 100597

Herbal medicines are an important part of healthcare worldwide. In Brazil, the national authorities issued the concept of “living pharmacies�, that produce and offer herbal medicines in the Brazilian unified public health system.

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Ethanolic extract, solvent fractions, and bio-oils from Urtica subincisa: Chemical composition, toxicity, and anti-IL-17 activity on HaCaT keratinocytes

Roberto Esquivel-García a,b, Ayca Seker c, Nehal I. Abu-Lail d, Manuel García-P �erez c, Alejandra Ochoa-Zarzosa b, Martha-Estrella García-P �erez

doi : 10.1016/j.hermed.2022.100599

Volume 36, December 2022, 100599

Urtica subincisa Benth has been used to treat skin inflammation for centuries by Purépechas, an ancient people that has left an important legacy to Mexican folk medicine.

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Formulation optimization and characterization of Pistacia atlantica Desf. essential oil-loaded nanostructured lipid carriers on the proliferation of human breast cancer cell line SKBR3 (in vitro studies)

Negin Najjari a, Soyar Sari a,*, Mostafa Saffari b, Hamidreza Kelidari c, Ali Nokhodchi

doi : 10.1016/j.hermed.2022.100600

Volume 36, December 2022, 100600

Breast cancer is among the most prevalent type of cancer in women across the world. The essential oils of Pistacia atlantica Desf. have been utilized as a medicine owing to their antibacterial, antioxidant, anti-inflammatory, and anticancer effects. The current research aims to enhance the anticancer effect of the essential oil of Pistacia atlantica Desf. by incorporating it in a nanostructured lipid carrier (NLC), a lipid-based drug delivery system.

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A phylogenetic perspective of antiviral species of the genus Artemisia (Asteraceae-Anthemideae): A proposal of anti SARS-CoV-2 (COVID-19) candidate taxa

Adil Hussain

doi : 10.1016/j.hermed.2022.100601

Volume 36, December 2022, 100601

Different classes of disease-causing viruses are widely distributed universally. Plant-based medicines are anticipated to be effective cures for viral diseases including the COVID-19, instigated by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). This study displays the phylogenetic perspective of Artemisia and proposes some candidate taxa against different viral diseases, including SARS-CoV-2.

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Cranberry (Vaccinium macrocarpon) as a prophylaxis for urinary tract infections in women: A systematic review with meta-analysis

Jessica Valente, Barbara A. Pendry, Eva Galante

doi : 10.1016/j.hermed.2022.100602

Volume 36, December 2022, 100602

Urinary tract infection (UTI) is a commonly acquired bacterial infection mostly in young, healthy women. Cranberry (Vaccinium macrocarpon) has historically been used for the treatment and prevention of UTIs; however, research has found conflicting evidence regarding its effectiveness for the prophylaxis of UTIs. The aim of this work is to evaluate the effectiveness of cranberry on the risk of UTI occurrences in women.

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Herbal products of Plantago species: International patents survey

Maria Helena Vendruscolo a, Gilsane Lino von Poser a, Am �elia Terezinnha Henriques a, Marina Cardoso Nemitz

doi : 10.1016/j.hermed.2022.100603

Volume 36, December 2022, 100603

The genus Plantago (Plantaginaceae) encompasses 250 species distributed worldwide, many of them used in traditional medicine. Technological advances regarding this genus are constantly being proposed. The target of this study was to carry out a patent survey of Plantago-based products and processes.

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Phenolic compounds and antimicrobial properties of mint and thyme

Mohsen Soleimani a, Ahmad Arzani b, Vida Arzani c,*, Thomas H. Roberts

doi : 10.1016/j.hermed.2022.100604

Volume 36, December 2022, 100604

Mint (Mentha spp.) and thyme (Thymus spp.) are two of the foremost aromatic herbs used in food and beverage products for their flavor, aromatic and medicinal qualities.

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Quercus infectoria gall loaded patches for wound dressing: A comparison of fabrication methods

Sema Tu ̆gçe Aydın a,d, Ilter Demirhan c, Mustafa S ̧ eng ̈or

doi : 10.1016/j.hermed.2022.100605

Volume 36, December 2022, 100605

Increasing antibiotic resistance leads wound care specialists to promote chronic wound healing with plant-based sources. The aim of this study is to extract Quercus infectoria gall and to investigate the performance of the extracted QIG wound dressings produced by three different fabrication techniques.

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Effects of phonophoresis of Aloe vera gel and ultrasound on knee osteoarthritis: A randomized controlled trial

Farzaneh Haghighat a, Sobhan Arjomand a, Samira Ghasemi a, Elnaz Afkhami a, Hashem Montaseri b, Alireza Motealleh

doi : 10.1016/j.hermed.2022.100606

Volume 36, December 2022, 100606

The present study aimed to investigate the effect of phonophoresis of Aloe vera gel (PHA) on pain intensity and functional status in patients with knee osteoarthritis (OA).

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Ethnopharmacological survey of plants prescribed by herbalists for traditional treatment of hypercholesterolemia in Casablanca, Morocco

Asma Arrout *,1,2, Yassine El Ghallab, Ibrahim Sbai El Otmani, Amal Ait Haj Said

doi : 10.1016/j.hermed.2022.100607

Volume 36, December 2022, 100607

The conventional treatments for hypercholesterolemia are too atomistic to effectively handle the condition. A phytotherapy which is rich in bioactive compounds could be a more effective approach. This study highlights plants prescribed against high cholesterol by herbalists in Casablanca, Morocco, and investigates their clinical effectiveness through a literature review.

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Network pharmacology-based analysis of the mechanism of Guben Sanjie Pill in the treatment of lung cancer

Kai Wang a,*, Lu Zhai a, Feng Li a, Yunyun Cao a, Pan Lu a, Xiaoning Liu a, Yarong Liu a, Na Li a, Xinhan Zhao

doi : 10.1016/j.hermed.2022.100608

Volume 36, December 2022, 100608

Lung cancer (LC) is a malignant tumor with the highest morbidity and mortality in the world. A traditional Chinese medicine formula, Guben Sanjie Pill (GBSJP), is an effective method for the clinical treatment of LC patients, but its molecular mechanism is unclear. Here, the aim was to detect the potential molecular mechanism of GBSJP in LC.

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A randomized comparative study of Kakrasingi (Pistacia integerrima J. L. Stewart ex Brandis) and metronidazole in bacterial vaginosis

Kahkashan Baig a, Arshiya Sultana a,*, Khaleequr Rahman

doi : 10.1016/j.hermed.2022.100609

Volume 36, December 2022, 100609

To determine and compare the efficacy of Kakrasingi (Pistacia integerrima J.L. Stewart ex Brandis) with metronidazole in bacterial vaginosis (BV).

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Clinical course of patients with severe SARS-CoV-2 infection co-treatment with Jin Si Herbal Tea in Eastern Taiwan: A retrospective cohort study

Pei-Chen Li a, Hui-Sheng Wang b, Marthandam Asokan Shibu c, Jhen Wang a, Shiau-Huei Huang a, Jeng-Hung Wang d, Ji-Hung Wang e,f,g, Chih-Yang Huang h,i,j,k,l, Chien-Yi Chiang c, Yu-Jung Lin c, Tsung-Jung Ho m,n,o, Shinn-Zong Lin p, Hui-Chun Chung q,r, Hsin-Yuan Yu m, San-Hua Su m, Ying-Fang Chou q,s, Chia-Hui Tai q,s, Dah-Ching Ding a,t,*, Cheng Yen Shih

doi : 10.1016/j.hermed.2022.100610

Volume 36, December 2022, 100610

Coronavirus disease-2019 (COVID-19) has affected more than 608 million people and has killed 6.5 million people in the world. A few studies showed traditional Chinese medicine can be beneficial for COVID-19 treatment.

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Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach

Abhay Tiwari a, Sushil Kumar b, Gourav Choudhir a, Garima Singh a, Upanshu Gangwar c, Vasudha Sharma d, Rupesh K. Srivastava e, Satyawati Sharma

doi : 10.1016/j.hermed.2022.100611

Volume 36, December 2022, 100611

Androgenic alopecia (AGA), scalp hair loss, occurs due to the hyperactivity of steroid 5α-reductase2 (SRD5A2), which metabolizes testosterone into 5α-dihydroxytestosterone. Finasteride, an FDA-approved drug producing many side effects, is a commonly used competitive inhibitor for SRD5A2 to treat AGA.

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Taraxacum spp. in vitro and in vivo anticancer activity – A review

Ana Isabel Oliveira a,1, Cl �audia Pinho a,1, Filipa Quintela Vieira b,c, Regina Silva b, Agostinho Cruz

doi : 10.1016/j.hermed.2022.100612

Volume 36, December 2022, 100612

Cancer is one of the major causes of death universally. Conventional chemotherapeutic agents are associated with severe side effects which limit their general acceptability and leads to a search for alternative efficient and safe options.

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Evaluation of anticoagulant and inflammatory effects of Tanacetum parthenium (L.) in a randomized controlled clinical trial

Mohammadreza Ataollahi a,1, Ebrahim Akrami b,2, Mehdi Kalani c,3, Malek Zarei d,4, Mahsa Rostami Chijan e,5, Massih Sedigh-Rahimabadi f,6, Hiva Alipanah

doi : 10.1016/j.hermed.2022.100613

Volume 36, December 2022, 100613

The use of aspirin in the primary prevention of diseases is debatable. Herbal products might be considered potential substitutes for synthetic chemicals in many situations.

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Corrigendum to “Evaluating the efficacy of Achillea millefolium ointment in the treatment of recurrent idiopathic epistaxis; A randomized double-blind clinical trial� [J. Herb. Med. 29 (2021) 100468]

Farnaz Hashemian a, Maliheh Akbarpour b, Keyvan Razaghi c, Amirhossein Emam d, Mohammadali Seiferabiei e, Farshad Hashemian

doi : 10.1016/j.hermed.2022.100552

Volume 36, December 2022, 100552

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