Journal of Herbal Medicine




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Efficacy of Salvadora persica root extract as an endodontic irrigant – An in-vitro evaluation

Fahd Aljarbou a,*,1, Abdurahman A. Niazy b,c,1, Rhodanne Nicole A. Lambarte c, Ramzi A. Mothana d, Abdulaziz Binrayes e, Mohammad Al-Obaida a, Hadi M. Alamri

doi : 10.1016/j.hermed.2022.100564

Volume 34, July 2022, 100564

The main reason for endodontic failure is bacteria and chemical irrigation using chemicals in the form of irrigation has been deemed effective. The objectives of this study were to evaluate the in vitro antimicrobial effects of Salvadora persica extract as an endodontic irrigant and to compare it with sodium hypochlorite (NaOCl).

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Effect of Alhagi maurorum distillate on ureteral stone expulsion: A single-blind randomized trial

Mohammad Reza Aryaeefar a, Ali Khakbaz b, Saeed Akbari b, Ali Movahedi c, Akram Gazerani a, Mohammad Bidkhori d, Vahid Moeini

doi : 10.1016/j.hermed.2022.100567

Volume 34, July 2022, 100567

The aim of this trial was to examine the effect of Alhagi maurorum distillate on ureteral stone expulsion.

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The effect of nettle root extract on urinary problems in older men with benign prostatic hyperplasia: A randomized clinical trial

Asieh Khalafi-Kheydani a,1, Hosein Mahmoodi b,2, Zohreh Sadat c,3, Ismail Azizi-Fini

doi : 10.1016/j.hermed.2022.100568

Volume 34, July 2022, 100568

Benign prostatic hyperplasia is one of the most common benign tumor in men. Due to frequent side effects associated with medications used to treat prostatic hyperplasia, the use of herbal plants such as nettle has increased for the management of this ailment.

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Study on heavy metals in some Ayurvedic herbal products and risk assessment of their calculated average daily dose intake in humans

Meena Deswal a,*, Pawan Deswal b, J.S. Laura

doi : 10.1016/j.hermed.2022.100569

Volume 34, July 2022, 100569

According to the World Health Organisation, 80% of the world population relies on plant material based herbal medicines for primary health care. Nine herbal products used in Ayurvedic medicine were studied for heavy metal content and assessed for their health risks.

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Effects of cordyceps sinensis supplementation during 12 weeks in amateur marathoners: A randomized, double-blind placebo-controlled trial

Fellipe Pinheiro Savioli a,*, Paulo Zogaib b, Eduardo Franco b, Fernando Cezar Alves de Salles b, Guilherme Vieira Giorelli c, Carlos Vicente Andreoli

doi : 10.1016/j.hermed.2022.100570

Volume 34, July 2022, 100570

Different substances have been tested for improving sports performance. One of these, Cordyceps sinensis (Ophiocordyceps sinensis), a fungus that only grows in high-altitude regions, caught the attention of the scientific community in 1993 when Chinese athletes broke world records in track and field. Since then, few papers have been published evaluating this supplement in an active population.

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Meta-analysis of the effects of quinoa (Chenopodium quinoa) interventions on blood lipids

Masoumeh Atefi a, Solmaz Mirzamohammadi b, Mina Darand c, Mohammad Javad Tarrahi

doi : 10.1016/j.hermed.2022.100571

Volume 34, July 2022, 100571

The purpose of the current study is to conduct a meta-analysis of published randomized controlled trials to explore the quantitative effect of quinoa supplementation on serum lipid concentrations.

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Brewed chicory leaf consumption has unexpected side effects along beneficial effects on liver enzymes in non-alcoholic fatty liver disease patients

Samira Faraji a,b, Mohammad Reza Mohammad Hosseini Azar c,*,1, Mohammad Alizadeh

doi : 10.1016/j.hermed.2022.100572

Volume 34, July 2022, 100572

Introduction: This randomized controlled trial study aimed to find the benefits and possible side effects of brewed chicory leaf consumption in non-alcoholic fatty liver disease (NAFLD) patients.

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An updated review on the antimicrobial and pharmacological properties of Uncaria (Rubiaceae)

Rehman Abdul , Mei-Rong Wang , Chao-Jie Zhong , Yuan-Yuan Liu , Wei Hou *, Hai-Rong Xiong

doi : 10.1016/j.hermed.2022.100573

Volume 34, July 2022, 100573

Rapidly emerging diseases, such as viral infections, cancer, and autoimmune disorders are becoming an increasing global health concern. Natural products, including plant extracts and compounds, possess an enormous spectrum of pharmacological activities, including antiviral, anticancer, immunomodulatory, anti-asthma, anti-diabetic, anti-hypertension, and anti-rheumatism activities.

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Saffron reduces some inflammation and oxidative stress markers in donepezil-treated mild-to-moderate Alzheimer's Disease patients: A randomized double-blind placebo-control trial

Leila Rasi Marzabadi a,b,1, Seyyed Mohammad Bagher Fazljou b,2, Mostafa Araj-Khodaei c,3,4, Saeed Sadigh-Eteghad a,b,5,6, Amirreza Naseri d,7,8, Mahnaz Talebi

doi : 10.1016/j.hermed.2022.100574

Volume 34, July 2022, 100574

Mounting evidence indicates the possible positive effects of Crocus sativus (saffron) on cognitive function in patients with Alzheimer’s Disease (AD). This study assessed the effects of saffron on cognitive outcomes and circulatory markers in patients with mild-to-moderate AD.

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Chemical characterization and in vitro biological evaluation of aqueous extract of Althaea officinalis L. flower grown in Lebanon

Cyrine Farhat a, Hicham Younes a, Osama A. Alyamani b, Marguerite Mrad c,d, Nancy Hourani c, Hala Khalifeh e, Yolla El-Makhour f, Ghassan Dbaibo c,d, Rouba Hage-Sleiman

doi : 10.1016/j.hermed.2022.100575

Volume 34, July 2022, 100575

Herbal medicine is extensively used in various therapeutic strategies. Althaea officinalis L. of the family Malvaceae exhibits many biological activities through its phenolic acids, flavonoids, coumarins and polysaccharides. In Lebanon, the flowers are consumed in hot infusions.

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Izkhar [Cymbopogon martinii (Roxb.)] Wats.: An evidence-based review on its phytochemical aspect and hepatoprotective traditional use in Unani medicine

Shabnam Anjum Ara *, Bilal Ahmad, Mohammad Fazil, Shaheen Akhlaq, Usama Akram, Merajul Haque, Asim Ali Khan

doi : 10.1016/j.hermed.2022.100576

Volume 34, July 2022, 100576

The therapeutic approach to medicine has witnessed a shift during the last few decades and herbal drugs are now in great demand globally. Valuable research is being carried out to evaluate the safety and efficacy of herbal drugs, in search of a holistic cure for various ailments. Liver diseases, for instance, are a serious health issue.

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Therapeutic evaluation of herbal formulation in acne vulgaris and its influence on quality of life—A single-arm clinical trial

Meenu Doni a, Mohammad Iliyas Patel a, Mohd Khalid a, Nazim Husain a,*, Mohd Qudrathullah Khan a, Bibi Ayesha

doi : 10.1016/j.hermed.2022.100577

Volume 34, July 2022, 100577

Acne vulgaris is a disease of the pilosebaceous unit that primarily affects teenagers and young adults. It relates to significant psychological morbidity and, on rare occasions, fatality due to suicidal tendencies.

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A socio-ecological critique on India’s local health traditions amidst rising incidence of global pandemics

Praveen Kumar Sharma a, Anchal Singh b, Naveen K. Sharma

doi : 10.1016/j.hermed.2022.100578

Volume 34, July 2022, 100578

The COVID-19 crisis has exposed inadequacy to deal with such health emergencies. The state of healthcare facilities in India is shambolic, which is further exacerbated by the exclusivity of modern health systems. The authors argue for vertical and horizontal expansion of the existing system to include traditional medicine systems, in favor of an urgently needed holistic and more inclusive healthcare system.

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Chinese and western herbal medicines for the topical treatment of psoriasis – A critical review of efficacy and safety

Wen-Hsin Tsou a,*, Michael Heinrich a, Anthony Booker

doi : 10.1016/j.hermed.2022.100579

Volume 34, July 2022, 100579

This critical review of randomized controlled trials (RTCs) was conducted to evaluate the efficacy and safety of herbal products used in the topical treatment of psoriasis.

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Honey with added value – enriched with rutin and quercetin from Sophora flower

Sofija �orđevi �c a,*, Nebojˇsa Nedi �c b, Aleksandra Pavlovi �c c, Duˇsanka Milojkovi �c-Opsenica c, ˇZivoslav Teˇsi �c c, Uroˇs Gaˇsi �c

doi : 10.1016/j.hermed.2022.100580

Volume 34, July 2022, 100580

The aim of this study was to find the best conditions for the extraction of rutin and quercetin from Sophora flower in acacia honey as an extractant, and to formulate a new product – honey with added value.

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Correlation of chemical composition and anticoagulant activity in different accessions of Brazilian Lippia alba (Verbenaceae)

Paula Mendonça Leite a,*,1, Ana Paula Nader Miranda a, Juliana Mendes Amorim a, Letícia Barbosa Santos a, Rita Carolina Figueiredo Duarte b, Vinícius Gonçalves Maltarollo a, Lyderson Facio Viccini c, Andr �e Augusto Gomes Faraco a, Maria das Graças Carvalho b, Rachel Oliveira Castilho

doi : 10.1016/j.hermed.2022.100581

Volume 34, July 2022, 100581

Lippia alba, popularly known as “cidreira� (lemon balm) is used to treat gastrointestinal disorders, anxiety, and insomnia. However, this species is known for its phenotypic plasticity and genome variation, resulting in variation of the chemical composition that can alter the pharmacological effect.

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Herbal medicine as a first-line choice of complementary medicine for South Indian parents/caregivers in the management of ASD children

Debi Ann Abraham a, Narasimhan Udayakumar b, Lavanya Rajendran a, Ramya Rajendran a, Muhasaparur Ganesan Rajanandh

doi : 10.1016/j.hermed.2022.100583

Volume 34, July 2022, 100583

Parents/caregivers of children with Autism Spectrum Disorder (ASD) try different approaches to manage their child’s condition, of which one of the popular approaches is using Complementary and Alternative Medicine (CAM) treatment.

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