European Heart Journal




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Heart failure in cardio-oncology and adult congenital heart disease: new challenges and therapeutic targets

Filippo Crea

doi : 10.1093/eurheartj/ehac621

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4443–4446

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From the garden to the clinic: how Mendelian randomization is shaping up atherosclerotic cardiovascular disease prevention strategies 

Benoit J Arsenault

doi : 10.1093/eurheartj/ehac394

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4447–4449

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CureHeart wins Big Beat Challenge, a £30 million research award from the British Heart Foundation 

Metin Avkiran

doi : 10.1093/eurheartj/ehac510

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4450–4452

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Bioelectronic medicine and its applications in cardiology 

Alberto Giannoni, Francesco Gentile, Claudio Passino

doi : 10.1093/eurheartj/ehac343

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4453–4455

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Antiplatelet therapy to prevent graft failure after coronary artery bypass graft: aspirin monotherapy for most, DAPT for selected few 

Rocco Vergallo, Carlo Patrono

doi : 10.1093/eurheartj/ehac503

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4456–4457

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Cardiovascular complications of immune checkpoint inhibitors for cancer 

Franck Thuny, Jarushka Naidoo, Tomas G Neilan

doi : 10.1093/eurheartj/ehac456

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4458–4468,

Over the last decade or so, there has been a paradigm shift in the oncologic care of patients with a range of solid tumour and haematologic malignancies, away from traditional cytotoxic chemotherapy and towards personalized cancer treatments, using both targeted therapy and immunotherapy.

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Predicting stroke in heart failure and reduced ejection fraction without atrial fibrillation 

Toru Kondo, Azmil H Abdul-Rahim, Atefeh Talebi, William T Abraham, Akshay S Desai, Kenneth Dickstein, Silvio E Inzucchi, Lars Køber, Mikhail N Kosiborod, Felipe A Martinez, Milton Packer, Mark Petrie, Piotr Ponikowski, Jean L Rouleau, Marc S Sabatine, Karl Swedberg, Michael R Zile, Scott D Solomon, Pardeep S Jhund, John J V McMurray

doi : 10.1093/eurheartj/ehac487

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4469–4479

Patients with heart failure with reduced ejection fraction (HFrEF) are at significant risk of stroke. Anticoagulation reduces this risk in patients with and without atrial fibrillation (AF), but the risk-to-benefit balance in the latter group, overall, is not favourable.

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Stroke risk stratification in patients with heart failure and sinus rhythm 

Dimitrios Sagris, Eduard Shantsila, Gregory Y H Lip

doi : 10.1093/eurheartj/ehac493

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4480–4482

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Last year of life of adults with congenital heart diseases: causes of death and patterns of care 

Liesbet Van Bulck, Eva Goossens, Lucas Morin, Koen Luyckx, Fouke Ombelet, Ruben Willems, Werner Budts, Katya De Groote, Julie De Backer, Lieven Annemans, Stéphane Moniotte, Michèle de Hosson, Arianne Marelli, Philip Moons, BELCODAC consortium

doi : 10.1093/eurheartj/ehac484

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4483–4492

Although life expectancy in adults with congenital heart diseases (CHD) has increased dramatically over the past five decades, still a substantial number of patients dies prematurely.

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A view from the end: what the last year of life can teach us about palliative care on the adult congenital heart disease journey 

Jill M Steiner, James N Kirkpatrick

doi : 10.1093/eurheartj/ehac492

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4493–4495

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A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity 

Dongchao Lu, Shambhabi Chatterjee, Ke Xiao, Isabelle Riedel, Cheng-Kai Huang, Alessia Costa, Sarah Cushman, Dimyana Neufeldt, Laura Rode, Arne Schmidt, Malte Juchem, Julia Leonardy, Gwen Büchler, Jonas Blume, Olivia-Luise Gern, Ulrich Kalinke, Wilson Lek Wen Tan, Roger Foo, Aryan Vink, Linda W van Laake, Peter van der Meer, Christian Bär, Thomas Thum

doi : 10.1093/eurheartj/ehac337

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4496–4511

Cardiotoxicity leading to heart failure (HF) is a growing problem in many cancer survivors. As specific treatment strategies are not available, RNA discovery pipelines were employed and a new and powerful circular RNA (circRNA)-based therapy was developed for the treatment of doxorubicin-induced HF.

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‘Circulating’ RNA-based therapies in Cardio-Oncology 

Carlo G Tocchetti, Alessandra Ghigo, Emilio Hirsch

doi : 10.1093/eurheartj/ehac407

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4512–4514

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Pulmonary haemodynamics and pulmonary congestion: where are we now? 

Nicole K Bart, Eugene Kotlyar, Anne M Keogh

doi : 10.1093/eurheartj/ehac499

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Page 4515

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Pulmonary vascular reserve with exercise in heart failure 

Kazunori Omote, Barry A Borlaug

doi : 10.1093/eurheartj/ehac540

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Pages 4516–4517

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Hypertrophic cardiomyopathy with extreme outflow tract obstruction 

Jeffrey B Geske, Elizabeth H Stephens, Joseph A Dearani

doi : 10.1093/eurheartj/ehac439

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Page 4518

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Inflammatory infiltration of the cardiac conduction system in acute lymphocytic myocarditis

Juan Caro-Codón, Samuel López Muñoz, Esteban López-de-Sa

doi : 10.1093/eurheartj/ehac507

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Page 4519

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Corrigendum to: 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC)

doi : 10.1093/eurheartj/ehac458

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Page 4468

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Corrigendum to: Tigray Siege and its impact on cardiology services in Mekelle University Hospital: a call to action

doi : 10.1093/eurheartj/ehac529

European Heart Journal, Volume 43, Issue 42, 7 November 2022, Page 4482

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