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The challenge of predicting sudden cardiac death: complementary role of risk scores, genetic testing, and clinical judgement
Filippo Crea
doi : 10.1093/eurheartj/ehac451
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3001–3004
An update on global epidemiology in heart failureÂ
Peter Moritz Becher, Lars H Lund, Andrew J S Coats, Gianluigi Savarese
doi : 10.1093/eurheartj/ehac248
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3005–3007
Cardiovascular meta-analyses: fool’s gold or gold for fools?Â
Giuseppe Biondi-Zoccai, Stephan Windecker, Peter Juni, Deepak L Bhatt
doi : 10.1093/eurheartj/ehac312
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3008–3013
Cardiac xenotransplantation: a new path for the treatment of advanced heart failure?Â
Eugene Braunwald
doi : 10.1093/eurheartj/ehac276
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3014–3015
The absolute cardiovascular benefits of PCSK9 inhibitors and ezetimibe added to maximally tolerated statin therapy depend on individual baseline cardiovascular riskÂ
Giovanna Liuzzo, Carlo Patrono
doi : 10.1093/eurheartj/ehac360
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3016–3017
Electromechanical reciprocity and arrhythmogenesis in long-QT syndrome and beyondÂ
Katja E Odening, Henk J van der Linde, Michael J Ackerman, Paul G A Volders, Rachel M A ter Bekke
doi : 10.1093/eurheartj/ehac135
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3018–3028
An abundance of literature describes physiological and pathological determinants of cardiac performance, building on the principles of excitation–contraction coupling.
Implantable defibrillators in primary prevention of genetic arrhythmias. A shocking choice?Â
Domenico Corrado, Mark S Link, Peter J Schwartz
doi : 10.1093/eurheartj/ehac298
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3029–3040
Many previously unexplained life-threatening ventricular arrhythmias and sudden cardiac deaths (SCDs) in young individuals are now recognized to be genetic in nature and are ascribed to a growing number of distinct inherited arrhythmogenic diseases.
Arrhythmic risk prediction in arrhythmogenic right ventricular cardiomyopathy: external validation of the arrhythmogenic right ventricular cardiomyopathy risk calculatorÂ
Paloma Jordà , Laurens P Bosman, Alessio Gasperetti, Andrea Mazzanti, Jean Baptiste Gourraud, Brianna Davies, Tanja Charlotte Frederiksen, Zoraida Moreno Weidmann, Andrea Di Marco, Jason D Roberts, Ciorsti MacIntyre, Colette Seifer, Antoine Delinière, Wael Alqarawi, Deni Kukavica, Damien Minois, Alessandro Trancuccio, Marine Arnaud, Mattia Targetti, Annamaria Martino, Giada Oliviero, Daniel C Pipilas, Corrado Carbucicchio, Paolo Compagnucci, Antonio Dello Russo, Iacopo Olivotto, Leonardo Calò, Steven A Lubitz, Michael J Cutler, Philippe Chevalier, Elena Arbelo, Silvia Giuliana Priori, Jeffrey S Healey, Hugh Calkins, Michela Casella, Henrik Kjærulf Jensen, Claudio Tondo, Rafik Tadros, Cynthia A James, Andrew D Krahn, Julia Cadrin-Tourigny
doi : 10.1093/eurheartj/ehac289
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3041–3052
Arrhythmogenic right ventricular cardiomyopathy (ARVC) causes ventricular arrhythmias (VAs) and sudden cardiac death (SCD). In 2019, a risk prediction model that estimates the 5-year risk of incident VAs in ARVC was developed (ARVCrisk.com).
Importance of genotype for risk stratification in arrhythmogenic right ventricular cardiomyopathy using the 2019 ARVC risk calculatorÂ
Alexandros Protonotarios, Riccardo Bariani, Chiara Cappelletto, Menelaos Pavlou, Alba GarcÃa-GarcÃa, Alberto Cipriani, Ioannis Protonotarios, Adrian Rivas, Regitze Wittenberg, Maddalena Graziosi, Zafeirenia Xylouri, José M Larrañaga-Moreira, Antonio de Luca, Rudy Celeghin, Kalliopi Pilichou, Athanasios Bakalakos, Luis Rocha Lopes, Konstantinos Savvatis, Davide Stolfo, Matteo Dal Ferro, Marco Merlo, Cristina Basso, Javier Limeres Freire, Jose F Rodriguez-Palomares, Toru Kubo, Tomas Ripoll-Vera, Roberto Barriales-Villa, Loizos Antoniades, Jens Mogensen, Pablo Garcia-Pavia, Karim Wahbi, Elena Biagini, Aris Anastasakis, Adalena Tsatsopoulou, Esther Zorio, Juan R Gimeno, Jose Manuel Garcia-Pinilla, Petros Syrris, Gianfranco Sinagra, Barbara Bauce, Perry M Elliott
doi : 10.1093/eurheartj/ehac235
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3053–3067
To study the impact of genotype on the performance of the 2019 risk model for arrhythmogenic right ventricular cardiomyopathy (ARVC).
Arrhythmogenic right ventricular cardiomyopathy: the never-ending quest for a risk calculatorÂ
Estelle Gandjbakhch, Annina S Vischer
doi : 10.1093/eurheartj/ehac324
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3068–3070,
Importance of genetic testing in unexplained cardiac arrestÂ
Steffany Grondin, Brianna Davies, Julia Cadrin-Tourigny, Christian Steinberg, Christopher C Cheung, Paloma Jorda, Jeffrey S Healey, Martin S Green, Shubhayan Sanatani, Wael Alqarawi, Paul Angaran, Laura Arbour, Pavel Antiperovitch, Habib Khan, Richard Leather, Peter G Guerra, Lena Rivard, Christopher S Simpson, Martin Gardner, Ciorsti MacIntyre, Colette Seifer, Anne Fournier, Jacqueline Joza, Michael H Gollob, Guillaume Lettre, Mario Talajic, Zachary W Laksman, Jason D Roberts, Andrew D Krahn, Rafik Tadros
doi : 10.1093/eurheartj/ehac145
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3071–3081
Genetic testing is recommended in specific inherited heart diseases but its role remains unclear and it is not currently recommended in unexplained cardiac arrest (UCA). We sought to assess the yield and clinical utility of genetic testing in UCA using whole-exome sequencing (WES).
Explaining the unexplained: applying genetic testing after cardiac arrest and sudden deathÂ
Elijah R Behr
doi : 10.1093/eurheartj/ehac172
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages 3082–3084
Superior vena cava obstruction induced by pacemaker leads resulting in downhill esophageal varices
Kazuya Mori, Kenichiro Yamagata, Hiroki Horinouchi, Kengo Kusano
doi : 10.1093/eurheartj/ehac281
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Page 3085
Catastrophic atrial tachycardia-induced cardiomyopathy in a teenager treated by extracorporeal membrane oxygenation and stereotactic arrhythmia radioablation
Qingyong Chen, Bai Sen, Xu Feng, Qing Yang
doi : 10.1093/eurheartj/ehac325
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Page 3086
A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathyÂ
Julia Cadrin-Tourigny, Laurens P Bosman, Anna Nozza, Weijia Wang, Rafik Tadros, Aditya Bhonsale, Mimount Bourfiss, Annik Fortier, Øyvind H Lie, Ardan M Saguner, Anneli Svensson, Antoine Andorin, Crystal Tichnell, Brittney Murray, Katja Zeppenfeld, Maarten P van den Berg, Folkert W Asselbergs, Arthur A M Wilde, Andrew D Krahn, Mario Talajic, Lena Rivard, Stephen Chelko, Stefan L Zimmerman, Ihab R Kamel, Jane E Crosson, Daniel P Judge, Sing Chien Yap, Jeroen F van der Heijden, Harikrishna Tandri, Jan D H Jongbloed, Marie Claude Guertin, J Peter van Tintelen, Pyotr G Platonov, Firat Duru, Kristina H Haugaa, Paul Khairy, Richard N W Hauer, Hugh Calkins, Anneline S J M te Riele, Cynthia A James
doi : 10.1093/eurheartj/ehac180
European Heart Journal, Volume 43, Issue 32, 21 August 2022, Pages e1–e9
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is characterized by ventricular arrhythmias (VAs) and sudden cardiac death (SCD). We aimed to develop a model for individualized prediction of incident VA/SCD in ARVC patients.
