European Heart Journal




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The far-reaching beneficial effects of sodium–glucose co-transporter 2 inhibitors in heart failure

Filippo Crea

doi : 10.1093/eurheartj/ehac437

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2907–2910

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What cardiologists should know about sleep 

Martino Francesco Pengo, Sogol Javaheri, Manuel Sanchez-de-la-Torre, Esther Irene Schwarz

doi : 10.1093/eurheartj/ehac349

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2911–2913

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Frankfurt scientists lead the way with funding for three visionary research projects 

Judith Ozkan

doi : 10.1093/eurheartj/ehac316

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2914–2915

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A multinational European network to implement integrated care in elderly multimorbid atrial fibrillation patients: the AFFIRMO Consortium 

Søren P Johnsen, Marco Proietti, Aldo P Maggioni, Gregory Y H Lip

doi : 10.1093/eurheartj/ehac265

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2916–2918

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The UK TAVI trial: an independent, pragmatic study extending the evidence for the treatment of symptomatic severe aortic stenosis 

Rocco Vergallo, Massimo Volpe

doi : 10.1093/eurheartj/ehac345

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2919–2920

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Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease 

Maarten van Smeden, Georg Heinze, Ben Van Calster, Folkert W Asselbergs, Panos E Vardas, Nico Bruining, Peter de Jaegere, Jason H Moore, Spiros Denaxas, Anne Laure Boulesteix, Karel G M Moons

doi : 10.1093/eurheartj/ehac238

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2921–2930

The medical field has seen a rapid increase in the development of artificial intelligence (AI)-based prediction models. With the introduction of such AI-based prediction model tools and software in cardiovascular patient care, the cardiovascular researcher and healthcare professional are challenged to understand the opportunities as well as the limitations of the AI-based predictions.

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Non-steroidal mineralocorticoid receptor antagonists in cardiorenal disease 

Arjun K Pandey, Deepak L Bhatt, Francesco Cosentino, Nikolaus Marx, Ori Rotstein, Bertram Pitt, Ambarish Pandey, Javed Butler, Subodh Verma

doi : 10.1093/eurheartj/ehac299

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2931–2945

Despite existing treatments, patients with heart failure and chronic kidney disease (CKD) remain at high risk for adverse outcomes and progression to end-stage disease. Steroidal mineralocorticoid receptor antagonists (MRAs) such as spironolactone and eplerenone reduce mortality but remain under-prescribed due to the perceived risk of hyperkalaemia and hormonal side effects.

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Anti-interleukin-1 agents for pericarditis: a primer for cardiologists 

Massimo Imazio, George Lazaros, Marco Gattorno, Martin LeWinter, Antonio Abbate, Antonio Brucato, Allan Klein

doi : 10.1093/eurheartj/ehab452

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2946–2957

Anti-interleukin (IL)-1 agents have been developed for the treatment of autoinflammatory and rheumatic conditions, where overproduction of IL-1 is an important pathophysiologic process.

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Obesity and effects of dapagliflozin on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus in the DECLARE–TIMI 58 trial 

Kazuma Oyama, Itamar Raz, Avivit Cahn, Julia Kuder, Sabina A Murphy, Deepak L Bhatt, Lawrence A Leiter, Darren K McGuire, John P H Wilding, Kyong Soo Park, Assen Goudev, Rafael Diaz, Jindřich Špinar, Ingrid A M Gause-Nilsson, Ofri Mosenzon, Marc S Sabatine, Stephen D Wiviott

doi : 10.1093/eurheartj/ehab530

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2958–2967

We investigated the associations between obesity, cardiorenal events, and benefits of dapagliflozin in patients with type 2 diabetes mellitus (T2DM).

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Obesity, heart failure, and SGLT2 inhibition: DECLARE-TIMI 58 provides insights 

Naveed Sattar, Stefan D Anker, Javed Butler, Subodh Verma

doi : 10.1093/eurheartj/ehab709

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2968–2970

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Post-operative atrial fibrillation and risk of heart failure hospitalization 

Parag Goyal, Michael Kim, Udhay Krishnan, Stephen A Mccullough, Jim W Cheung, Luke K Kim, Ambarish Pandey, Barry A Borlaug, Evelyn M Horn, Monika M Safford, Hooman Kamel

doi : 10.1093/eurheartj/ehac285

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2971–2980

Post-operative atrial fibrillation (POAF) is associated with stroke and mortality. It is unknown if POAF is associated with subsequent heart failure (HF) hospitalization. This study aims to examine the association between POAF and incident HF hospitalization among patients undergoing cardiac and non-cardiac surgeries.

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Post-operative AF and heart failure hospitalizations: what remains hidden in patients undergoing surgery  

Melissa E Middeldorp, Christine M Albert

doi : 10.1093/eurheartj/ehac335

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2981–2983

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Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled 

João Pedro Ferreira, Faiez Zannad, Javed Butler, Gerasimos Filipattos, Ivana Ritter, Elke Schüler, Bettina J Kraus, Stuart J Pocock, Stefan D Anker, Milton Packer

doi : 10.1093/eurheartj/ehac306

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2984–2993

Hyperkalaemia frequently leads to interruption and discontinuation of neurohormonal antagonists, which may worsen heart failure prognosis. Some studies suggested that sodium-glucose cotransporter 2 inhibitors reduce hyperkalaemia, an effect that may have important clinical implications. This analysis evaluates the effect of empagliflozin on the occurrence of hyper- and hypokalaemia in HF.

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Emerging role for SGLT2 inhibitors in mitigating the risk of hyperkalaemia in heart failure 

Subodh Verma, Nitish K Dhingra, Arjun K Pandey, Francesco Cosentino

doi : 10.1093/eurheartj/ehac304

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Pages 2994–2996

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The sounds of silence 

Alessandro Parolari, Rui M S Almeida, William E Boden,

doi : 10.1093/eurheartj/ehac333

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Page 2997,

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Left main revascularization: breaking through the sounds of silence 

Mario Gaudino, Michael E Farkouh, Gregg W Stone

doi : 10.1093/eurheartj/ehac340

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Page 2998

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Paroxysmal massive mitral regurgitation

Xin Wei, Minggang Zhou, Yong Chen, Mao Chen

doi : 10.1093/eurheartj/ehac318

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Page 2999

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Popeye’s sign and transthyretin amyloidosis

Nobuhiro Tahara, Akihiro Honda, Mitsuharu Ueda, Yoshihiro Fukumoto

doi : 10.1093/eurheartj/ehac330

European Heart Journal, Volume 43, Issue 31, 14 August 2022, Page 3000

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