Circulation




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What Is the Future of Factor XI Inhibitors?.

Weitz, Jeffrey I. MD; Eikelboom, John W. MBBS

doi : 10.1161/CIRCULATIONAHA.122.061132

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Clinical Characteristics, Incidences, and Mortality Rates for Type A and B Aortic Dissections: A Nationwide Danish Population-Based Cohort Study From 1996 to 2016.

Obel, Lasse M. MD; Lindholt, Jes S. MD, PhD, DMSc; Lasota, Anne N. MD, PhD; Jensen, Henrik K. MD, PhD, DMSc; Benhassen, Leila L. MD, PhD; Morkved, Amalie L. MD; Srinanthalogen, Reshaabi MD; Christiansen, Malina BMSc; Bundgaard, Henning MD, PhD, DMSc; Liisberg, Mads MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.061065

Population-based epidemiologic studies of aortic dissections (ADs) are needed. This study aimed to report clinical characteristics, incidences, and mortality rates for adult patients admitted to Danish hospitals with type A AD (TAAD) or type B AD (TBAD) from 1996 through 2016.

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Single High-Sensitivity Point-of-Care Whole-Blood Cardiac Troponin I Measurement to Rule Out Acute Myocardial Infarction at Low Risk.

Apple, Fred S. PhD; Smith, Stephen W. MD; Greenslade, Jaimi H. PhD; Sandoval, Yader MD; Parsonage, William DM; Ranasinghe, Isuru MBChB, MMed, PhD; Gaikwad, Niranjan MD, MMed, PhD; Schulz, Karen DC; Stephensen, Laura RN; Schmidt, Christian W. MS; Okeson, Brynn MS; Cullen, Louise MBBS; on behalf of the SAMIE Investigators; Brownlee, Emily; Fincher, Gavin; Hall, Emma; Hancock, Rebecca; Gangathimmaiah, Vinay; Hamilton-Craig, Christian; Hobbins-King, Andrew; Keijzers, Gerben; Bayat, Maryam Khorramshahi; McCormick, Ellyse; Mahmoodi, Ehsan; Perez, Siegfried; Staib, Andrew; Zournazi, Anna; Than, Martin

doi : 10.1161/CIRCULATIONAHA.122.061148

High-sensitivity cardiac troponin (hs-cTn) laboratory assays are used to rule out myocardial infarction (MI) on presentation, but prolonged result turnaround times can delay patient management.

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Circulating c-Met-Expressing Memory T Cells Define Cardiac Autoimmunity.

Fanti, Silvia MSc ,*; Stephenson, Edward MD, PhD ,,*; Rocha-Vieira, Etel PhD; Protonotarios, Alexandros MD; Kanoni, Stavroula PhD; Shahaj, Eriomina PhD; Longhi, M. Paula PhD; Vyas, Vishal S. MD; Dyer, Carlene PhD; Pontarini, Elena PhD; Asimaki, Angeliki PhD; Bueno-Beti, Carlos PhD; De Gaspari, Monica MD; Rizzo, Stefania MD, PhD; Basso, Cristina MD, PhD; Bombardieri, Michele MD, PhD; Coe, David PhD; Wang, Guosu BSc; Harding, Daniel MD; Gallagher, Iain PhD; Solito, Egle PhD; Elliott, Perry MD; Heymans, Stephane MD, PhD; Sikking, Maurits MD; Savvatis, Konstantinos MD, PhD; Mohiddin, Saidi A. MD ,,*; Marelli-Berg, Federica M. MD, PhD ,,*

doi : 10.1161/CIRCULATIONAHA.121.055610

Autoimmunity is increasingly recognized as a key contributing factor in heart muscle diseases. The functional features of cardiac autoimmunity in humans remain undefined because of the challenge of studying immune responses in situ.

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Straight to the Heart: T Cells That Specifically Target Cardiac Tissue.

Abplanalp, Wesley T. PhD ,,,,*; Merten, Maximilian MS ,,,,*; Dimmeler, Stefanie PhD

doi : 10.1161/CIRCULATIONAHA.122.061324

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Metabolic Changes Associated With Cardiomyocyte Dedifferentiation Enable Adult Mammalian Cardiac Regeneration.

Cheng, Yuan-Yuan PhD; Gregorich, Zachery PhD; Prajnamitra, Ray P. PhD; Lundy, David J. PhD; Ma, Ting-Yun BS; Huang, Yu-Hsuan BS; Lee, Yi-Chan MS; Ruan, Shu-Chian BS; Lin, Jen-Hao MS; Lin, Po-Ju MS; Kuo, Chiung-Wen PhD; Chen, Peilin PhD; Yan, Yu-Ting PhD; Tian, Rong MD, PhD; Kamp, Timothy J. MD, PhD; Hsieh, Patrick C.H. MD, PhD

doi : 10.1161/CIRCULATIONAHA.122.061960

Cardiac regeneration after injury is limited by the low proliferative capacity of adult mammalian cardiomyocytes (CMs). However, certain animals readily regenerate lost myocardium through a process involving dedifferentiation, which unlocks their proliferative capacities.

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Shortness of Breath and Near Syncope During Exertion in a Child: When-Patients-Worry Syndrome.

Hattendorf, Brandy MD; Reddy, S. Chandra Bose MD

doi : 10.1161/CIRCULATIONAHA.122.062620

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Cannabis Inhalation Acutely Reduces Muscle Sympathetic Nerve Activity in Humans.

Cheung, Christian P. MSc ,*; Nardone, Massimo MSc ,*; Lee, Jordan B. MSc; Baker, Ryleigh E.; Millar, Philip J. PhD ,,+; Burr, Jamie F. PhD ,+

doi : 10.1161/CIRCULATIONAHA.122.062564

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2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces.

Wyckoff, Myra H. MD; Greif, Robert MD, MME; Morley, Peter T. MBBS; Ng, Kee-Chong MBBS, Mmed(Peds); Olasveengen, Theresa M. MD, PhD; Singletary, Eunice M. MD; Soar, Jasmeet MA, MB, BChir; Cheng, Adam MD; Drennan, Ian R. ACP, PhD; Liley, Helen G. MBChB; Scholefield, Barnaby R. MBBS, MRCPCH, PhD; Smyth, Michael A. BSc(Hons), MSc, PhD; Welsford, Michelle MD, BSc; Zideman, David A. LVO, QHP(C), MBBS; Acworth, Jason MBBS, FRACP(PEM); Aickin, Richard MBChB; Andersen, Lars W. MD, MPH, PhD, DMSc; Atkins, Diane MD; Berry, David C. PhD, MHA; Bhanji, Farhan MD, MSc(Ed); Bierens, Joost MD, PhD, MCDM, MCPM; Borra, Vere PhD; Bottiger, Bernd W. MD, ML, DEAA; Bradley, Richard N. MD; Bray, Janet E. RN, PhD; Breckwoldt, Jan MD, MME; Callaway, Clifton W. MD, PhD; Carlson, Jestin N. MD, MS; Cassan, Pascal MD; Castren, Maaret MD, PhD; Chang, Wei-Tien MD, PhD; Charlton, Nathan P. MD; Chung, Sung Phil MD, PhD; Considine, Julie RN, PhD; Costa-Nobre, Daniela T. MD, MHS, PhD; Couper, Keith RN, PhD; Couto, Thomaz Bittencourt MD, PhD; Dainty, Katie N. MSc, PhD; Davis, Peter G. MBBS, MD; de Almeida, Maria Fernanda MD, PhD; de Caen, Allan R. MD; Deakin, Charles D. MA, MD; Djarv, Therese MD, PhD; Donnino, Michael W. MD; Douma, Matthew J. PhD(c), MN, RN; Duff, Jonathan P. MD; Dunne, Cody L. MD; Eastwood, Kathryn PhD, BParamedicStud, BNurse; El-Naggar, Walid MD; Fabres, Jorge G. MD, MSPH; Fawke, Joe MBChB; Finn, Judith PhD, RN; Foglia, Elizabeth E. MD, MA, MSCE; Folke, Fredrik MD, PhD; Gilfoyle, Elaine MD, MMEd; Goolsby, Craig A. MD, MEd *; Granfeldt, Asger MD, PhD, DMSc; Guerguerian, Anne-Marie MD, PhD; Guinsburg, Ruth MD, PhD; Hirsch, Karen G. MD; Holmberg, Mathias J. MD, MPH, PhD; Hosono, Shigeharu MD, PhD; Hsieh, Ming-Ju MD, MSc, PhD; Hsu, Cindy H. MD, PhD; Ikeyama, Takanari MD; Isayama, Tetsuya MD, MSc, PhD; Johnson, Nicholas J. MD; Kapadia, Vishal S. MD, MSCS; Kawakami, Mandira Daripa MD, PhD; Kim, Han-Suk MD, PhD; Kleinman, Monica MD; Kloeck, David A. MBBCh, FCPaed, Crit Care (SA); Kudenchuk, Peter J. MD; Lagina, Anthony T. MD; Lauridsen, Kasper G. MD, PhD; Lavonas, Eric J. MD, MS; Lee, Henry C. MD, MS; Lin, Yiqun (Jeffrey) MD, MHSc, PhD; Lockey, Andrew S. MBChB, PhD; Maconochie, Ian K. MBBS, LMSSA, PhD; Madar, R. John MBBS; Malta Hansen, Carolina MD, PhD; Masterson, Siobhan PhD; Matsuyama, Tasuku MD, PhD; McKinlay, Christopher J.D. MBChB, PhD, DipProfEthics; Meyran, Daniel MD; Morgan, Patrick MBChB, DipIMC, RCSEd; Morrison, Laurie J. MD, MSc; Nadkarni, Vinay MD +; Nakwa, Firdose L. MBBCh, MMed (Paeds); Nation, Kevin J. NZRN; Nehme, Ziad PhD; Nemeth, Michael MA; Neumar, Robert W. MD, PhD; Nicholson, Tonia MBBS, BScPsych; Nikolaou, Nikolaos MD; Nishiyama, Chika RN, DrPH; Norii, Tatsuya MD; Nuthall, Gabrielle A. MBChB; O'Neill, Brian J. MD; Ong, Yong-Kwang Gene MBBS, MRCPCH; Orkin, Aaron M. MD, MSc, PHH, PhD; Paiva, Edison F. MD, PhD; Parr, Michael J. MBBS; Patocka, Catherine MDCM, MHPE; Pellegrino, Jeffrey L. PhD, MPH; Perkins, Gavin D. MBChB, MMEd, MD; Perlman, Jeffrey M. MBChB; Rabi, Yacov MD; Reis, Amelia G. MD, PhD; Reynolds, Joshua C. MD, MS; Ristagno, Giuseppe MD, PhD; Rodriguez-Nunez, Antonio MD, PhD; Roehr, Charles C. MD, PhD; Rudiger, Mario MD, PhD; Sakamoto, Tetsuya MD, PhD; Sandroni, Claudio MD; Sawyer, Taylor L. DO, Med; Schexnayder, Steve M. MD; Schmolzer, Georg M. MD, PhD; Schnaubelt, Sebastian MD; Semeraro, Federico MD; Skrifvars, Markus B. MD, PhD; Smith, Christopher M. MD, MSc; Sugiura, Takahiro MD, PhD; Tijssen, Janice A. MD, MSc; Trevisanuto, Daniele MD; Van de Voorde, Patrick MD, PhD; Wang, Tzong-Luen MD, PhD, JM; Weiner, Gary M. MD; Wyllie, Jonathan P. MBChB; Yang, Chih-Wei MD, PhD; Yeung, Joyce PhD, MBChB; Nolan, Jerry P. MBChB; Berg, Katherine M. MD; Collaborators; Burdick, Madeline C. MD; Cartledge, Susie BN(Hons), PhD; Dawson, Jennifer A. RN, PhD; Elgohary, Moustafa M. MBChB; Ersdal, Hege L. MD, PhD; Finan, Emer MBBCh, MEd; Flaatten, Hilde I.; Flores, Gustavo E. MD, NRP; Fuerch, Janene MD; Garg, Rakesh MD; Gately, Callum MBChB; Goh, Mark SL, MBBS; Halamek, Louis P. MD; Handley, Anthony J. MD, FRCP; Hatanaka, Tetsuo MD, PhD; Hoover, Amber MSN, RN; Issa, Mohmoud MD; Johnson, Samantha MA; Kamlin, C. Omar MBBS, DMedSci; Ko, Ying-Chih MD; Kule, Amy MD; Leone, Tina A. MD; MacKenzie, Ella BSc; Macneil, Finlay MB, BS; Montgomery, William MD; O'Dochartaigh, Domhnall MSc, RN; Ohshimo, Shinichiro MD, PhD; Palazzo, Francesco Stefano MBBS, BSc; Picard, Christopher CD, BSN, RN; Quek, Bin Huey MMed (Paeds), MRCP (Paeds); Raitt, James MbChB(Hons); Ramaswamy, Viraraghavan V. MD, DM; Scapigliati, Andrea MD; Shah, Birju A. MD, MPH, MBA; Stewart, Craig BSc, BMBS, MRCPCH; Strand, Marya L. MD, MS; Szyld, Edgardo MD, MSc; Thio, Marta MD, PhD; Topjian, Alexis A. MD, MSCE; Udaeta, Enrique MD; Vaillancourt, Christian MD, MSc; Wetsch, Wolfgang A. MD; Wigginton, Jane MD, MSCS; Yamada, Nicole K. MD, MS; Yao, Sarah HW, MBBS; Zace, Drieda PhD; Zelop, Carolyn M. MD

doi : 10.1161/CIR.0000000000001095

AB This is the sixth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

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An Overview of Telehealth in the Management of Cardiovascular Disease: A Scientific Statement From the American Heart Association.

Takahashi, Edwin A. MD, Chair; Schwamm, Lee H. MD, FACC, Vice Chair; Adeoye, Opeolu M. MD, FACC; Alabi, Olamide MD; Jahangir, Eiman MD, MPH, FACC; Misra, Sanjay MD, FACC; Still, Carolyn H. PhD, MSM; on behalf of the American Heart Association Council on Cardiovascular Radiology and Intervention, Council on Hypertension, Council on the Kidney in Cardiovascular Disease, and Stroke Council

doi : 10.1161/CIR.0000000000001107

AB Telehealth enables the remote delivery of health care through telecommunication technologies and has substantially affected the evolving medical landscape. The COVID-19 pandemic accelerated the utilization of telehealth as health care professionals were forced to limit face-to-face in-person visits.

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Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2022 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2022.

doi : 10.1161/CIR.0000000000001116

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