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Smartwatch-Detected Atrial Fibrillation: The "Value" in the Positive Predictive Value.
Marcus, Gregory M. MD, MAS
doi : 10.1161/CIRCULATIONAHA.122.062292
Volume 146(23) pgs. 1733-1804,e326-e330 December 06, 2022
Apixaban for Patients With Atrial Fibrillation on Hemodialysis: A Multicenter Randomized Controlled Trial.
Pokorney, Sean D. MD, MBA; Chertow, Glenn M. MD; Al-Khalidi, Hussein R. PhD; Gallup, Dianne MS; Dignacco, Pat BA; Mussina, Kurt MBA; Bansal, Nisha MD; Gadegbeku, Crystal A. MD; Garcia, David A. MD; Garonzik, Samira PharmD; Lopes, Renato D. MD, PhD; Mahaffey, Kenneth W. MD; Matsuda, Kelly PharmD; Middleton, John P. MD; Rymer, Jennifer A. MD, MBA; Sands, George H. MD; Thadhani, Ravi MD; Thomas, Kevin L. MD; Washam, Jeffrey B. PharmD; Winkelmayer, Wolfgang C. MD; Granger, Christopher B. MD; on behalf of the RENAL-AF Investigators
doi : 10.1161/CIRCULATIONAHA.121.054990
There are no randomized data evaluating the safety or efficacy of apixaban for stroke prevention in patients with end-stage kidney disease on hemodialysis and with atrial fibrillation (AF).
Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and End-Stage Renal Disease: Lessons Learned.
Benz, Alexander P. MD, MSc; Eikelboom, John W. MBBS, MSc
The Effects of Angiotensin Receptor-Neprilysin Inhibition on Major Coronary Events in Patients With Acute Myocardial Infarction: Insights From the PARADISE-MI Trial.
Mehran, Roxana MD ,*; Steg, Philippe Gabriel MD ,*; Pfeffer, Marc A. MD, PhD; Jering, Karola MD, MPH; Claggett, Brian PhD; Lewis, Eldrin F. MD, MPH; Granger, Christopher MD; Kober, Lars MD; Maggioni, Aldo MD; Mann, Douglas L. MD; McMurray, John J.V. MD; Rouleau, Jean-Lucien MD; Solomon, Scott D. MD; Ducrocq, Gregory MD; Berwanger, Otavio MD, PhD; De Pasquale, Carmine G. MD; Landmesser, Ulf MD; Petrie, Mark MD; Leng, David Sim Kheng MD; van der Meer, Peter MD, PhD; Lefkowitz, Martin MD; Zhou, Yinong MD; Braunwald, Eugene MD
doi : 10.1161/CIRCULATIONAHA.122.060841
In patients who survive an acute myocardial infarction (AMI), angiotensin-converting enzyme inhibitors decrease the risk of subsequent major cardiovascular events. Whether angiotensin-receptor blockade and neprilysin inhibition with sacubitril/valsartan reduce major coronary events more effectively than angiotensin-converting enzyme inhibitors in high-risk patients with recent AMI remains unknown.
Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage.
Ercu, Maria PhD ,,*; Mucke, Michael B. MD ,,,*; Pallien, Tamara MS ,,*; Marko, Lajos MD, PhD ,,,*; Sholokh, Anastasiia MS; Schachterle, Carolin PhD; Aydin, Atakan PhD; Kidd, Alexa MD; Walter, Stephan MD; Esmati, Yasmin; McMurray, Brandon J. BSc; Lato, Daniella F. PhD; Yumi Sunaga-Franze, Daniele PhD; Dierks, Philip H.; Flores, Barbara Isabel Montesinos; Walker-Gray, Ryan PhD; Gong, Maolian MD; Merticariu, Claudia BS; Zuhlke, Kerstin PhD; Russwurm, Michael PhD; Liu, Tiannan MD; Batolomaeus, Theda U.P. MS; Pautz, Sabine MS; Schelenz, Stefanie; Taube, Martin; Napieczynska, Hanna PhD; Heuser, Arnd MD; Eichhorst, Jenny Dipl.-Ing. (FH); Lehmann, Martin PhD; Miller, Duncan C. PhD; Diecke, Sebastian PhD; Qadri, Fatimunnisa PhD; Popova, Elena PhD; Langanki, Reika BS; Movsesian, Matthew A. MD; Herberg, Friedrich W. PhD; Forslund, Sofia K. PhD; Muller, Dominik N. PhD; Borodina, Tatiana PhD; Maass, Philipp G. PhD; Bahring, Sylvia PhD; Hubner, Norbert MD; Bader, Michael PhD; Klussmann, Enno PhD
doi : 10.1161/CIRCULATIONAHA.122.060210
Phosphodiesterase 3A (PDE3A) gain-of-function mutations cause hypertension with brachydactyly (HTNB) and lead to stroke. Increased peripheral vascular resistance, rather than salt retention, is responsible.
Activation of Phosphodiesterase 3A: New Hope for Cardioprotection.
Chiong, Mario PhD; Houslay, Miles D. PhD; Lavandero, Sergio PhD
Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.
Manta, Calin-Petru Dr biol hum ,,*; Leibing, Thomas MD ,,,*; Friedrich, Mirco MSc; Nolte, Hendrik Dr rer nat; Adrian, Monica; Schledzewski, Kai Dr rer nat; Krzistetzko, Jessica MSc; Kirkamm, Christof; David Schmid, Christian MD; Xi, Yannick; Stojanovic, Ana PhD; Tonack, Sarah Dr rer nat; de la Torre, Carolina PhD; Hammad, Seddik Dr med vet; Offermanns, Stefan MD; Kruger, Marcus PhD; Cerwenka, Adelheid PhD; Platten, Michael MD; Goerdt, Sergij MD ,,+; Geraud, Cyrill MD ,,,+
doi : 10.1161/CIRCULATIONAHA.121.058615
Scavenger receptors Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are preferentially expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating plasma molecules controlling distant organ homeostasis.
Potassium Intake Linked With Heart Benefits.
Kuehn, Bridget M.
Yield of Cardiac Magnetic Resonance Imaging in a Preparticipation Cohort of Young Asian Males With T Wave Inversion.
Thiagarajan, Nishanth MBBS; Ho, Wilbert H.H. MBBS; Lim, Daniel Y.Z. MBBS; Loo, Wesley T.W. MBBS; Shen, Goy MBBS; Sundar, Vahul MBBS; Lim, Huai Yang MBBS; Lim, Lian Kiat MBBS; Chua, Terrance S.J. MBBS; Lim, Paul C.Y. MBBS; Tang, Hak Chiaw MBBS; Koh, Choong Hou MBBS; Yeo, Tee Joo MBBS; Chong, Daniel T.T. MBBS
Letter by Song et al Regarding Article, "Associations of Dietary Cholesterol, Serum Cholesterol, and Egg Consumption With Overall and Cause-Specific Mortality: Systematic Review and Updated Meta-Analysis".
Song, Yuxuan MS ,*; Ding, Congcong MS ,*; Xu, Tao MD
Response by Zhao et al to Letter Regarding Article, "Associations of Dietary Cholesterol, Serum Cholesterol, and Egg Consumption With Overall and Cause-Specific Mortality: Systematic Review and Updated Meta-Analysis".
Zhao, Bin PhD; Albanes, Demetrius MD; Huang, Jiaqi PhD
Correction to: A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction.
