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Pathogenesis, immunology, and immune-targeted management of the multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS): EAACI Position Paper
Wojciech Feleszko, Magdalena Okarska-NapieraÅ‚a, Emilie Pauline Buddingh, Marketa Bloomfield, Anna Sediva, Carles Bautista-Rodriguez, Helen A. Brough, Philippe A. Eigenmann, Thomas Eiwegger, Andrzej Eljaszewicz, Stefanie Eyerich, Cristina Gomez-Casado, Alain Fraisse, Jozef Janda, Rodrigo Jiménez-Saiz, Tilmann Kallinich, Inge Kortekaas Krohn, Charlotte G. Mortz, Carmen Riggioni, Joaquin Sastre, Milena Sokolowska, Ziemowit Strzelczyk, Eva Untersmayr, Gerdien Tramper-Stranders, for the Immunology Section and Working Group Infections of the EAACI
doi : 10.1111/pai.13900
Multisystem inflammatory syndrome in children (MIS-C) is a rare, but severe complication of coronavirus disease 2019 (COVID-19). It develops approximately 4 weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and involves hyperinflammation with multisystem injury, commonly progressing to shock.
Mode of delivery and offspring atopic dermatitis in a Swedish nationwide study
Mwenya Mubanga, Cecilia Lundholm, Elin S. Rohlin, Gustaf Rejnö, Bronwyn K. Brew, Catarina Almqvist
doi : 10.1111/pai.13904
Atopic dermatitis is a common chronic childhood disease associated with significant morbidity and healthcare costs. There is a known association between caesarean section and asthma, but the relationship between caesarean section and offspring atopic dermatitis remains uncertain.
Ambient prenatal air pollution exposure is associated with low cord blood IL-17a in infants
Olga Gorlanova, Heide Oller, Andrea Marten, Loretta Müller, Jessica Laine-Carmelli, Fabienne Decrue, Yasmin Salem, Danielle Vienneau, Kees de Hoogh, Amanda Gisler, Jakob Usemann, Insa Korten, Sophie Yammine, Uri Nahum, Noemi Künstle, Pablo Sinues, Sven Schulzke, Philipp Latzin, Oliver Fuchs, Martin Röösli, Bianca Schaub, Urs Frey, the BILD study group
doi : 10.1111/pai.13902
Editorial comments on: “The mode of delivery and offspring atopic dermatitis in a Swedish nationwide study�
Victoria X. Soriano, Philippe Eigenmann, Rachel L. Peters
doi : 10.1111/pai.13906
“Inborn errors of immunity: An expanding horizon through a multitude of biological pathways�
Fabio Candotti, Philippe Eigenmann
doi : 10.1111/pai.13908
Phenotype-specific signatures of systems-level gut microbiome associated with childhood airway allergies
Chih-Yung Chiu, Ko-Chun Chang, Lun-Ching Chang, Chia-Jung Wang, Wen-Hung Chung, Wen-Ping Hsieh, Shih-Chi Su
doi : 10.1111/pai.13905
Perturbation of gut symbiosis has been linked to childhood allergic diseases. However, the underlying host–microbe interaction connected with specific phenotypes is poorly understood.
Dysfunctional breathing and its impact on asthma control in children and adolescents
Signe Vahlkvist, Louise Jürgensen, Tine Detlefsen Hell, Thomas Houmann Petersen, Poul-Erik Kofoed
doi : 10.1111/pai.13909
Dysfunctional breathing (DB) has been shown to negatively affect asthma control in adults, but for children and adolescents, the knowledge is scarce. DB is among others characterized by dyspnea and hyperventilation.
Preliminary pilot study results of the EAACI allergy educational needs in primary care pediatricians Task Force in managing allergic disorders
Martha Cabrera, Dermot Ryan, Michel Erlewyn-Lajeunesse, Michael Eliad Levin, Ana MartÃnez-Cañavate, Carmen Villaizán Pérez, Elizabeth Angier, Juan Trujillo, José Miguel Cárdenas-Rebollo, Laura Losappio, Laura Reali
doi : 10.1111/pai.13907
Editorial comment on: Short-acting β 2-agonist use and asthma exacerbations in Swedish children: A SABINA Junior study
Cristina Boccabella, Omer Kalayci, Philippe Eigenmann
doi : 10.1111/pai.13910
