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Fibroblast A20 and its suppressor DREAM regulate fibrosis in SSc
Sarah OnuoraÂÂ
doi : 10.1038/s41584-022-00886-1
Volume 19 Issue 1, January 2023
Pre-RA autoantibodies recognize arthritogenic gut bacterium
Robert PhillipsÂÂ
Targeting the DNA damage response attenuates SLE-associated B cell characteristics
Robert PhillipsÂÂ
Reversal of inflammatory priming prevents arthritic flares
Jessica McHughÂÂ
Mapping the immune landscape of MDA5+ dermatomyositis
Jessica McHughÂÂ
Understanding synovial cell diversity in post-traumatic OA
Jason S. Rockel & Mohit KapoorÂÂ
Hydroxychloroquine dose: balancing toxicity and SLE flare risk
Tiphaine Lenfant & Nathalie Costedoat-ChalumeauÂÂ
Can molecular dynamics facilitate the design of protein–protein-interaction inhibitors?
Masashi Honma & Hiroshi SuzukiÂÂ
Cartilage calcification in osteoarthritis: mechanisms and clinical relevance
Ilaria Bernabei, Alexander So, Nathalie Busso & Sonia NasiÂÂ
doi : 10.1038/s41584-022-00875-4
Pathological calcification of cartilage is a hallmark of osteoarthritis (OA). Calcification can be observed both at the cartilage surface and in its deeper layers.
Glycobiology of rheumatic diseases
Theresa Kissel, René E. M. Toes, Thomas W. J. Huizinga & Manfred WuhrerÂÂ
doi : 10.1038/s41584-022-00867-4
Glycosylation has a profound influence on protein activity and cell biology through a variety of mechanisms, such as protein stability, receptor interactions and signal transduction. In many rheumatic diseases, a shift in protein glycosylation occurs, and is associated with inflammatory processes and disease progression.
Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia
Ana Margarida Pinto, Rinie Geenen, Tor D. Wager, Mark A. Lumley, Winfried Häuser, Eva Kosek, Jacob N. Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J. Crofford, Mary-Ann Fitzcharles, Marina López-Solà, Mariana LuÃÂs, Tiago Reis Marques, Philip J. Mease, Filipe Palavra, Jamie L. Rhudy, Lucina Q. Uddin, Paula Castilho, Johannes W. G. Jacobs & José A. P. da SilvaÂÂ
doi : 10.1038/s41584-022-00873-6
Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other symptoms, and has a substantial socioeconomic impact.
