Nature Reviews Urology




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Is it time to rethink the current patient-reported outcome measures?

Findlay MacAskill, Arun Sahai, Majed Shabbir, Guy’s Post Pelvic Surgery Research Group & Tet Yap 

doi : 10.1038/s41585-022-00661-7

Volume 20 Issue 1, January 2023

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Understanding and managing the cardiovascular risks of androgen deprivation therapy for prostate cancer

Kerem Atalar & Prabhakar Rajan 

doi : 10.1038/s41585-022-00671-5

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PSMA-PET to detect prostate cancer recurrence after radiotherapy

Omar Alghazo & Michael O’Callaghan 

doi : 10.1038/s41585-022-00672-4

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A new vaccine for UTI

Louise Stone 

doi : 10.1038/s41585-022-00709-8

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Microfluidic sperm selection

Louise Stone 

doi : 10.1038/s41585-022-00689-9

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Urine microbiota differ in bladder cancer

Louise Stone 

doi : 10.1038/s41585-022-00690-2

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Effect of high glucose on E. coli

Louise Stone 

doi : 10.1038/s41585-022-00691-1

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Texture analysis for patient selection

Louise Stone 

doi : 10.1038/s41585-022-00692-0

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FOXA2–KIT-driven lineage plasticity in NEPC

Maria Chiara Masone 

doi : 10.1038/s41585-022-00694-y

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A new surgical procedure to treat BPH

Maria Chiara Masone 

doi : 10.1038/s41585-022-00695-x

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Single-cell and spatial sequencing of kidney cancer

Maria Chiara Masone 

doi : 10.1038/s41585-022-00697-9

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The prognostic role of stroma in UTUC

Maria Chiara Masone 

doi : 10.1038/s41585-022-00698-8

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Quality checkpoints in the MRI-directed prostate cancer diagnostic pathway

Tristan Barrett, Maarten de Rooij, Francesco Giganti, Clare Allen, Jelle O. Barentsz & Anwar R. Padhani 

doi : 10.1038/s41585-022-00648-4

Multiparametric MRI of the prostate is now recommended as the initial diagnostic test for men presenting with suspected prostate cancer, with a negative MRI enabling safe avoidance of biopsy and a positive result enabling MRI-directed sampling of lesions.

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Using PSMA imaging for prognostication in localized and advanced prostate cancer

Matthew J. Roberts, Tobias Maurer, Marlon Perera, Matthias Eiber, Thomas A. Hope, Piet Ost, Shankar Siva, Michael S. Hofman, Declan G. Murphy, Louise Emmett & Wolfgang P. Fendler 

doi : 10.1038/s41585-022-00670-6

The use of prostate-specific membrane antigen (PSMA)-directed applications in modern prostate cancer management has evolved rapidly over the past few years, helping to establish new treatment pathways and provide further insights into prostate cancer biology.

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Fatty acid metabolism reprogramming in ccRCC: mechanisms and potential targets

Sze Kiat Tan, Helen Y. Hougen, Jaime R. Merchan, Mark L. Gonzalgo & Scott M. Welford 

doi : 10.1038/s41585-022-00654-6

Lipid droplet formation is a defining histological feature in clear-cell renal cell carcinoma (ccRCC) but the underlying mechanisms and importance of this biological behaviour have remained enigmatic. De novo fatty acid (FA) synthesis, uptake and suppression of FA oxidation have all been shown to contribute to lipid storage, which is a necessary tumour adaptation rather than a bystander effect.

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