Cornea




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Utility of In Vivo Confocal Microscopy in Diagnosis of Acanthamoeba Keratitis: A Comparison of Patient Outcomes.

Lee, Hyunjoo J. MD, PhD *,+; Alipour, Fateme MD *; Cruzat, Andrea MD *; Posarelli, Matteo MD ++; Zheng, Lixin MD ++; Hamrah, Pedram MD *,++

doi : 10.1097/ICO.0000000000003184

Volume 42(2) pgs. 135-260,e3-e4 February 2023

The aim of this study was to compare outcomes between cases of Acanthamoeba keratitis (AK) diagnosed and treated with or without the use of in vivo confocal microscopy (IVCM).

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Low-Level Light Therapy Versus Intense Pulsed Light for the Treatment of Meibomian Gland Dysfunction: Preliminary Results From a Prospective Randomized Comparative Study.

Giannaccare, Giuseppe MD, PhD, FEBOphth *; Pellegrini, Marco MD, FEBOphth +,++,[S]; Carnovale Scalzo, Giovanna MD *; Borselli, Massimiliano MD *; Ceravolo, Domenico OD *; Scorcia, Vincenzo MD *

doi : 10.1097/ICO.0000000000002997

The purpose of this study was to evaluate and compare the safety and efficacy of low-level light therapy (LLLT) and intense pulsed light (IPL) for the treatment of meibomian gland dysfunction (MGD).

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Five-Year Safety and Efficacy of Femtosecond Laser-Assisted Descemet Membrane Endothelial Keratoplasty.

Sorkin, Nir MD *,+; Gouvea, Larissa MD *; Din, Nizar MBBS, BSc, FRCOphth *; Mimouni, Michael MD *; Alshaker, Sara MD *; Weill, Yishay MD *; Gendler, Shai MD *; Slomovic, Allan R. MD, FRCSC *; Chan, Clara C. MD, FRCSC, FACS *; Rootman, David S. MD, FRCSC *

doi : 10.1097/ICO.0000000000003019

The purpose of this study was to evaluate 5-year safety and efficacy outcomes of femtosecond-enabled Descemet membrane endothelial keratoplasty (F-DMEK) in patients with Fuchs' endothelial dystrophy (FED).

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Long-Term Follow-Up of Corneal Endothelial Cell Changes After Iris-Fixated Phakic Intraocular Lens Explantation.

Kim, Tae Young MD *,+; Moon, In Hee MD *,+; Park, Sung Eun MD *,++; Ji, Yong Woo MD *,[S]; Lee, Hyung Keun MD, PhD *,+,[P]

doi : 10.1097/ICO.0000000000003001

The purpose of this study was to evaluate long-term corneal endothelial cell changes and visual outcomes after iris-fixated phakic intraocular lens (pIOL) explantation in patients with endothelial damage and to investigate potential predictors of endothelial injury.

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Long-Term Zonal Average Analysis of Corneal Tomography in Keratoconus Eyes.

Lombardo, Giuseppe MEng, PhD *,+; Serrao, Sebastiano MD, PhD +,++; Lombardo, Marco MD, PhD +,++

doi : 10.1097/ICO.0000000000003016

The scope of this study was to investigate keratoconus progression using zonal average analysis of corneal tomography. Methods: The corneal tomographies of patients participating in initial baseline and all scheduled follow-up visits up to 4 years were analyzed.

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Diurnal Variation in Straylight in Patients With Fuchs Endothelial Corneal Dystrophy and Controls.

de Jong, Bram MD *; Brandi-Dohrn, Franziska +; van der Meulen, Ivanka J. E. MD, PhD *; van den Berg, Thomas J. T. P. PhD ++; Wacker, Katrin MD +

doi : 10.1097/ICO.0000000000003002

The goal of this study was to investigate diurnal changes in intraocular straylight in relation to other corneal parameters and subjective complaints in patients with Fuchs endothelial dystrophy and healthy controls.

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Randomized Prospective Evaluation of Microblepharoexfoliation BlephEx as Adjunctive Therapy in the Treatment of Chalazia.

Zhu, Daniel MD *; Gupta, Rohun R. BS *; Stein, Rebecca L. MD +; Quintero, Jose MD +; Morcos, Marcelle M. MD ++; Link, Timothy J. MD ++; Perry, Henry D. MD *,+,++

doi : 10.1097/ICO.0000000000003090

Chalazia are benign eyelid lesions caused by the obstruction and inflammatory reaction of the meibomian glands. Demodex mites are one potential cause of chalazia leading to mechanical obstruction of the meibomian gland.

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Binocular Visual Function Changes After Corneal Collagen Cross-linking in Patients With Keratoconus.

Fasciani, Romina MD *,+; Crincoli, Emanuele MD *,+; Fedeli, Chiara OD *,+; Rebecchi, Maria Teresa OD *,+; Senneca, Marco OD +; Mosca, Luigi MD *,+; Guccione, Laura MD *,+; Rizzo, Stanislao MD *,+,++

doi : 10.1097/ICO.0000000000003053

High-order aberrations (HOAs) have been demonstrated to profoundly affect both visual acuity and stereoacuity in patients with keratoconus. Corneal collagen cross-linking (CXL) has been proven to significantly lower HOAs in keratoconus.

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Cryopreserved Amniotic Membrane Using the TissueTuck Technique: A Sutureless Approach for Pterygium Surgery.

Desai, Neel R. MD; Adams, Bryan MS3

doi : 10.1097/ICO.0000000000003111

The purpose of this study was to evaluate the clinical outcomes of the TissueTuck technique in the management of pterygium. Methods: This was a single-center, retrospective review of patients with primary or recurrent pterygium that underwent surgical excision followed by application of cryopreserved amniotic membrane (AM) using the TissueTuck technique.

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The Relationship Between Caffeine Intake and Dry Eye Disease.

Magno, Morten Schjerven *,+,++; Utheim, Tor P. PhD *,[S]; Morthen, Mathias Kaurstad *,++; Snieder, Harold PhD [P]; Jansonius, Nomdo M. PhD ++; Hammond, Christopher J. MD ||,**; Vehof, Jelle PhD ++,++++,[S][S]

doi : 10.1097/ICO.0000000000002979

The aim of this study was to determine the association between caffeine intake and dry eye disease (DED) in the large, population-based LifeLines cohort in the Netherlands.

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Possible Synergistic Role of Cryo-Alcohol Therapy in Infectious Scleritis-Scope and Rationale for Expanding Indications and Review of the Literature.

Agarwal, Shweta MD, FRCS (Ed) *; Pandey, Sunita MD *; Srinivasan, Bhaskar MD *; Anand, Appakkudal R. PhD +; Iyer, Geetha MD, FRCS (Glasgow), FRCS (Ed), FRC Ophth *

doi : 10.1097/ICO.0000000000003007

The purpose of this study was to highlight the use of topical ethanol as an adjunct to cryotherapy, termed cryo-alcohol therapy, in the management of fungal/acanthamoeba scleritis along with a review of the literature.

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Establishing a Biomarker for the Prediction of Short-Term Graft Detachment After Descemet Membrane Endothelial Keratoplasty.

Muijzer, Marc B. MSc *; Noordmans, Herke-Jan PhD +; Delbeke, Heleen MD ++; Dickman, Mor M. MD, PhD [S]; Nuijts, Rudy M. M. A. MD, PhD [S]; Dunker, Suryan MD [S]; Imhof, Saskia M. MD, PhD *; Wisse, Robert P. L. MD, PhD *

doi : 10.1097/ICO.0000000000003006

The purpose of this study was to investigate the predictive value of pachymetry mapping 1 day after Descemet membrane endothelial keratoplasty (DMEK) as a biomarker for early graft detachment.

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Tear Cytokines Associated With Therapeutic Effects in Chronic Ocular Graft-Versus-Host Disease.

Ma, Jiao PhD *,+; Shen, Zhan MM *,+; Peng, Rongmei MD, PhD *,+; Li, Chendi PhD *,+; Zhao, Yinghan MB *,+; Hu, Bohao MB *,+; Hong, Jing MD, PhD *,+

doi : 10.1097/ICO.0000000000003081

The local application of antiinflammatory and immunosuppressive agents is an effective method for the treatment of ocular graft-versus-host disease (oGVHD); however, we noticed that some patients with oGVHD did not respond to topical therapy as well as many others.

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Prediction of Visual Acuity in Patients With Microbial Keratitis.

Woodward, Maria A. MD, MSc *,+; Niziol, Leslie M. MS *; Ballouz, Dena MD *; Lu, Ming-Chen MS *; Kang, Linda BS *; Thibodeau, Alexa MD *; Singh, Karandeep MD, MMSc ++,[S]

doi : 10.1097/ICO.0000000000003129

The purpose of this study was to predict visual acuity (VA) 90 days after presentation for patients with microbial keratitis (MK) from data at the initial clinical ophthalmic encounter.

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A Novel Murine Model of Endothelial Keratoplasty.

Nakagawa, Hayate MD, PhD; Blanco, Tomas PhD; Kahale, Francesca MD; Wang, Shudan MD; Musayeva, Aytan MD; Alemi, Hamid MD, MPH; Dohlman, Thomas H. MD; Dana, Reza MD, MPH, MSc

doi : 10.1097/ICO.0000000000003047

The purpose of this study was to establish a murine model of endothelial keratoplasty. Methods: Endothelial keratoplasty (EK) was performed using C57BL/6 donor and BALB/c recipient mice.

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Acceleration of Regeneration of the Corneal Endothelial Layer After Descemet Stripping Induced by the Engineered FGF TTHX1114 in Human Corneas in Organ Culture.

Pizzuto, Sarah BA; Duffey, Grace BA; Weant, Jessica BA; Eveleth, David PhD

doi : 10.1097/ICO.0000000000003098

Descemet stripping only (DSO, descemetorhexis without endothelial keratoplasty) is increasing in clinical use but can impose long recovery times. The objective of this research was to determine whether TTHX1114, an engineered analog of FGF1, could accelerate healing in corneas after DSO.

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Endodiathermal Tautening of Floppy or Irregular Iris in Endothelial Keratoplasty (Iridodiathermy).

Jacob, Soosan MS, FRCS, DNB *,+; Agarwal, Amar MS, FRCS, FRCO *; Rechichi, Miguel MD, PhD ++; Parker, Jack MD [S],[P]; Kumar, Dhivya Ashok MD *; Kumar, Arun BE *,+

doi : 10.1097/ICO.0000000000003153

AB Floppy or irregular irides may be seen during endothelial keratoplasty in complex cases or in eyes with damaged irides and may cause uneven air fill, retro-pupillary air escape, anterior bowing of iris, forward movement of lens-iris diaphragm, shallowing of anterior chamber (AC), bellowing and floppiness of iris, uneven AC depth, difficulty in inserting and opening graft, iris trauma, intraoperative bleeding, and iridodialysis.

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Comparison of the Modified Jones Tube Technique and the DMEK EndoGlide Technique With and Without Viscoelastic Material for DMEK Tissue Preparation.

Christopher, Karen L. MD *; Terrin, Staci CEBT +; Lohmeier, John BA, CEBT +; Hartman, Matthew MD *; Davidson, Richard S. MD *; Taravella, Michael J. MD *

doi : 10.1097/ICO.0000000000003178

The aim of this study was to compare endothelial cell loss for DMEK (Descemet membrane endothelial keratoplasty) tissue preparation techniques using the modified Jones tube and the DMEK EndoGlide with and without viscoelastic material to protect the endothelium.

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Accelerated Corneal Collagen Cross-Linking Protocols for Progressive Keratoconus: Systematic Review and Meta-analysis.

Karam, Mohammad MBChB *; Alsaif, Abdulmalik MBChB +; Aldubaikhi, Ahmed MBBS ++,[S]; Aljebreen, Meshaal MBBS [P]; Alazaz, Rand MBBS [P]; Alkhowaiter, Nahlaa MD [forms double vertical]; Almudhaiyan, Tariq MD **,++; Aljassar, Faisal FRCS *

doi : 10.1097/ICO.0000000000003124

The aim of this study was to compare the outcomes of 18 mW/cm2 (5 minutes) versus 9 mW/cm2 (10 minutes) accelerated corneal collagen cross-linking protocols in patients with progressive keratoconus.

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Regarding Treatment and Features of a Case Series of Patients With Hereditary Benign Intraepithelial Dyskeratosis.

Dandar, Rachel MD *; Cheung, Albert Y. MD *,+

doi : 10.1097/ICO.0000000000003173

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Reply.

Seely, Mason BS *; Jackson, Kevin MD +; Meeker, Austin MD +; Daluvoy, Melissa MD +

doi : 10.1097/ICO.0000000000003188

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