Cornea




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Keratoplasty Registries: Lessons Learned.

Chu, Hsiao-Sang MD *,+,++,[S]; Hu, Fung-Rong MD *,+; Liu, Hsin-Yu MD *,+,++; Srikumaran, Divya MD [S]

doi : 10.1097/ICO.0000000000003088

AB Clinical registries have been developed for decades in the field of ophthalmology, and they are especially well-suited to the study of keratoplasty practices. A comprehensive donor/recipient registry system can provide insight into donor, recipient, and surgical factors associated with immediate and long-term outcomes and adverse reactions.

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Mini-DMEK for the Treatment of Chronic Focal Corneal Endothelial Decompensation.

Handel, Alexander MD *; Siebelmann, Sebastian MD, PhD *; Matthaei, Mario MD, PhD *; Cursiefen, Claus MD, PhD *,+; Bachmann, Bjorn MD, PhD *

doi : 10.1097/ICO.0000000000003048

The purpose of the study was to evaluate the feasibility of mini-descemet membrane endothelial keratoplasty ("Mini-DMEK," graft diameter <5 mm) for the treatment of chronic focal corneal endothelial decompensation for reasons other than acute hydrops in patients with keratoconus.

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Development of a Nomogram to Predict Graft Survival After Descemet Stripping Endothelial Keratoplasty.

Cherkas, Elliot BS *; Cinar, Yasin MD +; Zhang, Qiang PhD, MPH, MS ++; Sharpe, James MS ++; Hammersmith, Kristin M. MD *,[S]; Nagra, Parveen K. MD *,[S]; Rapuano, Christopher J. MD *,[S]; Syed, Zeba A. MD *,[S]

doi : 10.1097/ICO.0000000000002958

The purpose of this study was to analyze Descemet stripping endothelial keratoplasty (DSEK) outcomes and develop a nomogram to compute the probability of 3- and 5-year DSEK graft survival based on risk factors.

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Yogurt Technique for Descemet Membrane Endothelial Keratoplasty Graft Preparation: Early Clinical Outcomes.

Moramarco, Antonio MD *,+,++,[S],[P],||; Romano, Vito MD +,++; Modugno, Rocco Luigi MD *; Coco, Giulia MD ++,[S]; Viola, Pietro MD [P]; Fontana, Luigi MD, PhD ||

doi : 10.1097/ICO.0000000000002995

The aim of this study was to evaluate the efficacy and safety of the Yogurt technique for Descemet membrane endothelial keratoplasty (DMEK) graft preparation.

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DMEK Without Postoperative Supine Posturing.

Parker, Jack S. MD, PhD *,+; Parker, John S. MD *; Tate, Hudson BS *; Melles, Gerrit R. J. MD, PhD +,++

doi : 10.1097/ICO.0000000000003000

The purpose of this study was to describe the incidence of graft detachment after Descemet membrane endothelial keratoplasty (DMEK) without postoperative supine posturing

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Trends in Keratoplasty Procedures During 2 Decades in a Major Tertiary Referral Center in Finland: 1995 to 2015.

Ala-Fossi, Olli MD *; Krootila, Kari MD, FEBO +; Kivela, Tero T. MD, FEBO *

doi : 10.1097/ICO.0000000000002990

The purpose of this study was to analyze trends in number, age-adjusted frequency, and type of keratoplasty in a major tertiary referral center, relative to patient and graft characteristics.

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Role of Blepharoexfoliation in Demodex Blepharitis: A Randomized Comparative Study.

Mohammad-Rabei, Hossein MD *; Arabi, Amir MD, MPH *; Shahraki, Toktam MD *; Rezaee-alam, Zahra MD *; Baradaran-rafii, Alireza MD *,+

doi : 10.1097/ICO.0000000000003046

The purpose of this study was to evaluate the safety and efficacy of blepharoexfoliation in the treatment of Demodex blepharitis. Methods: Patients with microscopically approved Demodex blepharitis were enrolled.

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Surgical Management of Intraocular Pressure With Ab Interno Canaloplasty in Postkeratoplasty Patients: 12-Month Results.

Riaz, Kamran M. MD *; Gill, Mohsain S. MD *; Murphy, David A. MD *; Ding, Kai PhD +; Khaimi, Mahmoud A. MD *

doi : 10.1097/ICO.0000000000003009

The purpose of this study was to report clinical outcomes of ab interno canaloplasty (ABiC) with the iTrack microcatheter (Nova Eye Medical, Fremont, CA) for surgical management of intraocular pressure (IOP) in postkeratoplasty patients.

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Socioeconomic Correlates of Keratoconus Severity and Progression.

Ahmad, Tessnim R. MD *; Kong, Alan W. BS +; Turner, Marcus L. BS +; Barnett, Jackson BA +; Kaur, Gurbani MS, BA +; O'Brien, Kieran S. PhD, MPH *,++; Pasricha, Neel D. MD *; Indaram, Maanasa MD *

doi : 10.1097/ICO.0000000000002993

The purpose of this study was to investigate the social determinants of health for keratoconus. Methods: In this retrospective cohort study of patients with keratoconus, the electronic health record was reviewed for keratometry, treatments received, clinical comorbidities, and social characteristics.

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Microbial Keratitis in Patients With Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Experience From a Tertiary Centre in Taiwan.

Tsai, Tsung-Ying MD *; Adiyabazar, Doyodmaa MD +; Hsiao, Ching-Hsi MD, PhD *,++; Pan, Li-Yen MD *; Chen, Shin-Yi MD [S]; Tsai, Yueh-Ju MD *,++; Chen, Chun-Bing MD ++,[P],[forms double vertical],**,++,++++,[S][S]; Chung, Wen-Hung MD, PhD ++,[P],[forms double vertical],**,++,++++,[S][S]; Ma, David Hui-Kang MD, PhD *,[P][P],[forms double vertical][forms double vertical],***

doi : 10.1097/ICO.0000000000003063

The purpose of this study was to analyze the clinical features, causative microorganisms, antibiotic susceptibility, and treatment outcomes in culture-proven microbial keratitis (MK) in patients with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and to analyze the potential risk factors.

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Validation and Repeatability of the Epidermolysis Bullosa Eye Disease Index in Dystrophic Epidermolysis Bullosa.

Chen, Vicki M. MD *; Kumar, V. S. Senthil PhD +; Noh, Elizabeth BA *; Perloff, Jennifer PhD +

doi : 10.1097/ICO.0000000000003017

Dystrophic epidermolysis bullosa (DEB) is a devastating condition that causes painful corneal abrasions and vision loss. Epidermolysis Bullosa Eye Disease Index (EB-EDI) for the first time captures and quantifies EB-specific assessment of ocular symptoms and activities of daily living scales.

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Deep Anterior Lamellar Keratoplasty: Can All Ruptures Be Fixed?.

Sarnicola, Caterina MD *,+; Sarnicola, Enrica MD +,++; Cheung, Albert Y. MD; [S]; Sarnicola, Vincenzo MD +

doi : 10.1097/ICO.0000000000003054

The aim of this study was to report our experience in managing different types of Descemet membrane (DM) ruptures during deep anterior lamellar keratoplasty (DALK).

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COVID-19 and Eye Banking: Ongoing Impacts of the Pandemic.

Ballouz, Dena MD *; Issa, Rafik BS *; Sawant, Onkar B. PhD +; Hurlbert, Susan CEBT ++; Titus, Michael S. CEBT ++; Zhou, Yunshu MS *,[S]; Musch, David C. PhD, MPH *,[P],||; Majmudar, Parag A. MD [P],||; Kumar, Ashok PhD **; Mian, Shahzad I. MD *

doi : 10.1097/ICO.0000000000003137

The purpose of this study was to assess the impact of ongoing waves of the COVID-19 pandemic and resulting guidelines on the corneal donor pool with resumption of clinical operations.

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In Situ-forming Collagen Hydrogels Crosslinked by Multifunctional Polyethylene Glycol as a Matrix Therapy for Corneal Defects: 2-Month Follow-up In Vivo.

Logan, Caitlin M. MD, PhD *; Fernandes-Cunha, Gabriella Maria PhD *; Chen, Fang PhD *,+; Le, Peter *,+; Mundy, David *; Na, Kyung Sun PhD ++; Myung, David MD, PhD *,+

doi : 10.1097/ICO.0000000000003104

We recently showed that in situ-forming collagen gels crosslinked through multifunctional polyethylene glycol (PEG) supported corneal epithelialization 7 days after treatment of lamellar keratectomy wounds.

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"Groove and Peel" Deep Anterior Lamellar Keratoplasty: How Deep Can You Go?.

Son, Hyeck-Soo MD *,+; Rigi, Mohammed MD *; Srikumaran, Divya MD *; Eberhart, Charles G. MD, PhD *; Jun, Albert S. MD, PhD *; Soiberman, Uri S. MD *

doi : 10.1097/ICO.0000000000003103

The aim of the current research was to measure the thickness of the residual central corneal bed after performing the manual "Groove and Peel" deep anterior lamellar keratoplasty (GP-DALK) technique on human cadaveric eyes.

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Antiamoebic Susceptibility in Acanthamoeba Keratitis: Comparison of Isolates From South India and Northern California.

Richardson, Quintin R. BS *; Prajna, Lalitha MD, DNB +; Elakkiya, Shanmugam MSc +; Kamal, Fathima Sulthana MSc +; Talbott, Maya MHS *; Prajna, Namperumalsamy Venkatesh MBBS, DO, DNB, FRCOphth ++; Rajaraman, Revathi MBBS, DO, MS [S]; Cevallos, Vicky MT *; Seitzman, Gerami D. MD *,[P]; Lietman, Thomas M. MD *,[P]; Keenan, Jeremy D. MD, MPH *,[P]

doi : 10.1097/ICO.0000000000003060

Outcomes of Acanthamoeba keratitis are often worse in India than in the United States. The goal of this study was to determine whether antiamoebic susceptibility patterns were different when comparing Acanthamoeba isolates from India with those of the United States.

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Unintentional Descemet Cleft Introduces Novel Mechanism of Maintenance of Corneal Clarity.

Sherif, Noha A. BA *; Fleischman, David MD, MS, FACS +; Knight, O'Rese J. MD +

doi : 10.1097/ICO.0000000000003099

The purpose of this study was to report a case of corneal transparency for 7 months after the formation and persistence of a Descemet fluid cleft. Methods: We report the case of a 64-year-old woman undergoing anterior chamber reformation 2 months after Baerveldt implantation of the right eye.

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Infectious Crystalline Keratopathy Secondary to Mycobacterium chelonae.

Bonnet, Clemence MD *,+; Onishi, Alex C. MD *; Aldave, Anthony J. MD *

doi : 10.1097/ICO.0000000000003125

The aim of this study was to describe the clinical presentation and multimodal imaging of a patient diagnosed with infectious crystalline keratitis (ICK) secondary to Mycobacterium chelonae.

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Ligneous Conjunctivitis Secondary to Viral Conjunctivitis.

Quintero-Estades, Jose A. MD *,+; Iacob, Codrin E. MD ++; Donnenfeld, Eric D. MD +,[S]; Perry, Henry D. MD +,[S]

doi : 10.1097/ICO.0000000000003154

AB Ligneous conjunctivitis is a rare cause of chronic conjunctivitis that may be triggered by ocular insults such as trauma or infections. We present an interesting case of ligneous conjunctivitis caused by a viral infection that responded well to conservative management.

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Sural Nerve Vertical Cross-Face Graft for Lacrimal Gland Neurotization to Improve Tear Secretion in Neurodeprivative Dry Eye.

Giannaccare, Giuseppe MD, PhD, FEBOphth *; Bolognesi, Federico MD +,++; Fogagnolo, Paolo MD [S]; Allevi, Fabiana MD [P]; Ruggiero, Federica MD +,++; Filipov, Iulian MD ||; Marchetti, Claudio MD +,++; Scorcia, Vincenzo MD *; Biglioli, Federico MD [P]

doi : 10.1097/ICO.0000000000003126

No specific interventions have been reported for the treatment of severe neurodeprivative dry eye disease owing to facial nerve palsy. We describe herein the feasibility of a novel surgical procedure to reinnervate the lacrimal gland and report the preliminary outcomes of the first series of patients who were treated accordingly.

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Clinically Based Automated Tracing and Tortuosity Estimation of Corneal Nerve Fibers From Confocal Microscopy Images.

Colonna, Alessia MSc; Scarpa, Fabio PhD

doi : 10.1097/ICO.0000000000003148

The purpose of this study was the development of an algorithm able to automatically trace corneal nerves and to estimate a nerve tortuosity index that is useful in clinical practice.

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Inadvertent Injection of Botox Into the Anterior Chamber of the Eye With Crystalline Deposition.

Bloomquist, Ryan F. PhD, DMD, MBA *; Fowler, Teresa E. MD +; Bloomquist, Doan T. MD ++

doi : 10.1097/ICO.0000000000003151

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