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Preliminary Evidence for the Sequentially Mediated Effect of Racism-Related Stress on Pain Sensitivity Through Sleep Disturbance and Corticolimbic Opioid Receptor Function
Janelle E. Letzen,* Carly Hunt,* Hiroto Kuwabara,y Lakeya S. McGill,z Matthew J. Reid,* Katrina R. Hamilton,* Luis F. Buenaver,* Emily Burton,* Rosanne Sheinberg,x Dean F. Wong,{ Michael T. Smith,* and Claudia M. Campbell
doi : 10.1016/j.jpain.2022.09.004
Volume 24, Issue 1, January 2023, Pages 1-18
Antiracism CoaliTION in Pain Research (ACTION-PR): Guiding Principles for Equity in Reporting
Anna M. HoodCalia A. Morais,PhDEdwin N. ArokeStaja Q. BookerLisa C. CampbellClaudia M. CampbellBurel R. GoodinMary R. JanevicFlavia P. KaposVani A. MathurEricka N. MerriwetherJanelle E. Letzen
doi : 10.1016/j.jpain.2022.11.002
Volume 24, Issue 1, January 2023, Pages 19-21
Editorial: Introducing New Reporting Guidelines to Address Inclusion, Diversity, Equity, Antiracism, and Accessibility: Implementation at The Journal of Pain
Tonya M. Palermo
doi : 10.1016/j.jpain.2022.11.001
Volume 24, Issue 1, January 2023, Pages 22-23
Perspectives on Participation in Clinical Trials Among Individuals With Pain, Depression, and/or Anxiety: An ACTTION Scoping Review
McKenzie C. Ferguson,* Ewan McNicol,y Bethea A. Kleykamp,z Karin Sandoval,* Simon Haroutounian,x Katherine J. Holzer,x Robert D. Kerns,{ Christin Veasley,k Dennis C. Turk,** and Robert H. Dworkin
doi : 10.1016/j.jpain.2022.09.001
Volume 24, Issue 1, January 2023, Pages 24-37
For individuals experiencing pain, the decision to engage in clinical trials may be influenced by a number of factors including current and past care, illness severity, physical functioning, financial stress, and caregiver support. Co-occurring depression and anxiety may add to these challenges.
Patient Reported Outcome Measures in Chronic Neuropathic Pain Clinical Trials – A Systematic Literature Review
Juliane Sachau,* Manon Sendel,* Marie Pechard,y Kathrin Schnabel,z Iris Schmieg,z Terkia Medkour,y Laurent Ecochard,x Markus Woischnik,{ Hiltrud Liedgens,k Esther Pogatzki-Zahn,z Ralf Baron,* and Didier Bouhassira
doi : 10.1016/j.jpain.2022.09.003
Volume 24, Issue 1, January 2023, Pages 38-54
In neuropathic pain clinical trials, the patient's perspective is often insufficiently reflected focusing mainly on pain intensity. Comparability of outcome assessment is limited due to heterogenous patient reported outcome measures (PROMs).
An Analysis of the Role of Mental Health in a Randomized Trial of a Walking Intervention for Black Veterans With Chronic Pain
Patrick J. Hammett,* ,y Johanne Eliacin,z,x,{ Una E. Makris,â•‘, **,yy,zz Kelli D. Allen,xx,{{ Robert D. Kerns,â•‘â•‘, *** Alicia Heapy,â•‘â•‘, *** Elizabeth S. Goldsmith,* ,y Laura A. Meis,*,y Brent C. Taylor,*,y Michael Saenger,yyy,zzz Lee J.S. Cross,* Tam Do,* Mariah Branson,* and Diana J. Burgess
doi : 10.1016/j.jpain.2022.07.002
Volume 24, Issue 1, January 2023, Pages 55-67
Black patients and those with co-occurring mental health disorders are disproportionately affected by chronic pain, but few interventions target these populations.
Small Synthetic Hyaluronan Disaccharide BIS014 Mitigates Neuropathic Pain in Mice
Juan-Fernando Padın,* ,y,z,1 Marcos Maroto,*,1 Jose Manuel Entrena,x Javier Egea,{ Eulalia Montell,k, * Josep Verges,k,y Manuela G. Lopez,* ,y,{,2 Enrique J. Cobos,*,2 and Antonio G. Garcıa*
doi : 10.1016/j.jpain.2022.07.014
Volume 24, Issue 1, January 2023, Pages 68-83
Neuropathic pain (NP) is a challenging condition to treat, as the need for new drugs to treat NP is an unmet goal. We investigated the analgesic potential of a new sulfated disaccharide compound, named BIS014.
Perturbations in Neuroinflammatory Pathways Are Associated With a Worst Pain Profile in Oncology Patients Receiving Chemotherapy
Joosun Shin, RN, MSN* Kord M. Kober, PhD*,# Carolyn Harris, RN, BSN, PhDc* Kate Oppegaard, RN, MS* Alejandra Calvo-Schimmel, RN, PhD* Steven M. Paul, PhD* Bruce A. Cooper, PhD* Adam Olshen, PhDy Vasuda Dokiparthi,* Yvette P. Conley, PhDz Marilyn Hammer, RN, PhDx Jon D. Levine, MD, PhDy and Christine Miaskowski, RN, PhD
doi : 10.1016/j.jpain.2022.08.007
Volume 24, Issue 1, January 2023, Pages 84-97
Unrelieved pain occurs in 55% of cancer patients. Identification of molecular mechanisms for pain may provide insights into therapeutic targets. Purpose was to evaluate for perturbations in neuroinflammatory pathways between oncology patients with and without severe pain. Worst pain severity was rated using a 0 to 10 numeric rating scale six times over two cycles of chemotherapy.
Cannabidiol and Delta-9-Tetrahydrocannabinol Interactions in Male and Female Rats With Persistent Inflammatory Pain
Stevie C. Britch,*,y and Rebecca M. Craft
doi : 10.1016/j.jpain.2022.09.002
Volume 24, Issue 1, January 2023, Pages 98-111
Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC), 2 of the primary constituents of cannabis, are used by some individuals to self-treat chronic pain. It is unclear whether the pain-relieving effects of CBD alone and in combination with THC are consistent across genders and among types of pain.
A Comparison of Self-reported Pain Measures Between Sensory Phenotypes in HIV-associated Sensory Neuropathy
Harriet I. Kemp,* Jan Vollert,*,x,{,k Nicholas W.S. Davies,y Graeme J. Moyle,z and Andrew S.C. Rice*
doi : 10.1016/j.jpain.2022.09.005
Volume 24, Issue 1, January 2023, Pages 112-127
Painful HIV-associated neuropathy (HIV-SN) is a prevalent co-morbidity of HIV infection. Sensory phenotyping, using quantitative sensory testing (QST) could allow for improved stratification to guide personalized treatment. However, previous methods of QST interpretation have demonstrated limited association with self-reported pain measures.
High Blood Glucose and Excess Body fat Enhance Pain Sensitivity and Weaken Pain Inhibition in Healthy Adults: A Single-blind Cross-over Randomized Controlled Trial
Di Ye,* Timothy J. Fairchild,y Lechi Vo,* and Peter D. Drummond
doi : 10.1016/j.jpain.2022.09.006
Volume 24, Issue 1, January 2023, Pages 128-144
To investigate links between blood glucose, body fat mass and pain, the effects of acute hyperglycaemia on pain sensitivity and pain inhibition were examined in healthy adults with normal (n = 24) or excess body fat (n = 20) determined by dual-energy X-ray absorptiometry.
Twenty-year Outcomes of a Pediatric Chronic Abdominal Pain Cohort: Early Adulthood Health Status and Offspring Physical and Behavioral Health
Amanda L. Stone,* ,y Isabel Epstein,* ,z Stephen Bruehl,* Judy Garber,x Craig A. Smith,x and Lynn S. Walker
doi : 10.1016/j.jpain.2022.09.007
Volume 24, Issue 1, January 2023, Pages 145-156
Chronic abdominal pain (CAP) represents a common pediatric primary pain disorder that can have long-term effects on physical and mental health into adulthood.
Potential Misfortunes in ‘Making Sense’: A Cross-Sectional Study in People with Chronic Pain
Lance M. McCracken,* and Whitney Scott
doi : 10.1016/j.jpain.2022.09.008
Volume 24, Issue 1, January 2023, Pages 157-166
Making sense of one's circumstances is normally regarded as helpful, including in the context of chronic pain. However, sense-making may be associated with adverse impacts in daily functioning.
The Effect of Observing High or Low Pain on the Development of Central Sensitization
Diana M. Torta,* Elke Meyers,* Klaartje Polleunis,* Sarah De Wolf,* Ann Meulders,*,y and Emaneul N van den Broeke
doi : 10.1016/j.jpain.2022.09.009
Volume 24, Issue 1, January 2023, Pages 167-177
It is unknown whether watching other people in high pain increases mechanical hypersensitivity induced by pain. We applied high-frequency electrical stimulation (HFS) on the skin of healthy volunteers to induce pinprick mechanical hypersensitivity.
Considering Precision and Utility When we Talk About Pain. Comment on Cohen et al
Graham L. MoseleyNeil PearsonRoland ReezigtVictoria J. MaddenMark R. HutchinsonMartin DunbarAnneke J. BeetsmaHayley B. LeakePete MooreLaura SimonsLauren HeathcoteCormac RyanCarolyn BerrymanAmelia K. MardonBenedict M. Wand
doi : 10.1016/j.jpain.2022.05.010
Volume 24, Issue 1, January 2023, Pages 178-181
Reply to: “Pain is Not a “thing�: How That Error Affects Language and Logic in Pain Medicine�
Simon van Rysewyk
doi : 10.1016/j.jpain.2022.08.006
Volume 24, Issue 1, January 2023, Pages 182-183
Response to van Rysewyk S and Moseley GL et al.’s Comments on Cohen et al. J Pain 2022; 23(8):1283-1293
Milton CohenAsaf WeismanJohn Quintner
doi : 10.1016/j.jpain.2022.11.003
Volume 24, Issue 1, January 2023, Pages 184-185
