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Side effect profile of pharmacologic therapies for liver fibrosis in nonalcoholic fatty liver disease: a systematic review and network meta-analysis.
Li, Yilin a,*; Lei, Rong b,*; Lei, Honglin a; Xiong, Qin a; Xie, Fengjiao a; Yao, Chengjiao a; Feng, Peimin a
doi : 10.1097/MEG.0000000000002471
AB Several studies have found that antifibrosis treatment for nonalcoholic fatty liver disease (NAFLD) can cause a variety of side effects. No network meta-analysis (NMA) analyzes the adverse events of antifibrotic drugs for NAFLD.
Active smoking is associated with the development of adverse events of biological therapy in patients with inflammatory bowel disease.
Theodoraki, Eirini; Orfanoudaki, Eleni; Petroulaki, Eleni; Foteinogiannopoulou, Kalliopi; Koutroubakis, Ioannis E.
doi : 10.1097/MEG.0000000000002445
Smoking has been associated with lower levels of anti-TNF agents, higher antibodies and a reduced response to anti-TNF in patients with inflammatory bowel disease (IBD).
Alcohol and cannabis consumption in patients with inflammatory bowel disease: prevalence, pattern of consumption and impact on the disease.
Martinho-Grueber, Maude a,*; Kapoglou, Ioannis a,*; Bravo, Francisco a; Sarraj, Riad a; Benz, Eileen a; Restellini, Sophie b; Biedermann, Luc c; Rogler, Gerhard c; Vavricka, Stephan R. c,d; Schoepfer, Alain e; Maillard, Michel H. e,f; Michetti, Pierre e,f; Brunner, Felix g; Clair, Carole h; Barry, Mamadou Pathe i; Pittet, Valerie i; von Kanel, Roland j; Juillerat, Pascal a
doi : 10.1097/MEG.0000000000002453
There is little guidance regarding the impact of alcohol and cannabis on the clinical course of inflammatory bowel disease. The aim of this study was to assess the prevalence, sociodemographic characteristics and impact of alcohol and cannabis use on the clinical course of the disease.
Accuracy of narrow-band imaging in predicting the histology of anal intraepithelial lesions.
Pecere, Silvia a,b; Hassan, Cesare c,d; La Milia, Daniele e; Villani, Valeria f; Fuccio, Lorenzo g; Costamagna, Guido a,b; Petruzziello, Lucio a,b; Gizzi, Giuseppe f
doi : 10.1097/MEG.0000000000002457
Anal intraepithelial neoplasia (AIN) is the precursor of anal squamous carcinoma, frequently underappreciated by most gastroenterologists. Purpose of the study is to assess the diagnostic accuracy of narrow-band imaging (NBI) in predicting the histology of anal lesions, considering a new NBI classification.
Prediction of acute lung injury in severe acute pancreatitis by routine clinical data.
Jia, Mengyu; Xu, Xiaorong; Zhou, Shu; Liu, Hua; Zhao, Yan; Xu, Yaping; Tang, Maochun; Wu, Deqing
doi : 10.1097/MEG.0000000000002458
Acute lung injury (ALI) is a common complication of severe acute pancreatitis (SAP) with a high mortality. Early prediction of patients at risk in initial stage can improve the long-term survival.
Retreatment with anti-tumor necrosis factor therapy in combination with an immunomodulator for recurrence of Crohn's disease after ileocecal resection results in prolonged continuation as compared to anti-tumor necrosis factor monotherapy.
ten Bokkel Huinink, Sebastiaan. a; Beelen, Evelien M.J. a; ten Bokkel Huinink, Thomas b; Hoentjen, Frank c,d,m; G. L. Bodelier, Alexander e; Dijkstra, Gerard f; Romberg-Camps, Marielle g; de Boer, Nanne K. h; Stassen, Laurents P.S. i; van der Meulen, Andrea E. j; West, Rachel k; van Ruler, Oddeke l; van der Woude, C. Janneke a; de Vries, Annemarie C. a; On behalf of the Dutch Initiative on Crohn and Colitis (ICC)
doi : 10.1097/MEG.0000000000002474
A considerable proportion of Crohn's disease patients that undergo ileocecal resection (ICR) have failed anti-tumor necrosis factor (TNF) therapy preoperatively. This study aimed to assess the effectiveness of retreatment of anti-TNF therapy in patients with postoperative recurrence.
Oral omeprazole and diclofenac intake is associated with increased faecal calprotectin levels: a randomised open-label clinical trial.
Rendek, Zlatica a,b; Falk, Magnus c,d; Grodzinsky, Ewa b; Kechagias, Stergios e,c; Hjortswang, Henrik f,c
doi : 10.1097/MEG.0000000000002473
Nonsteroidal anti-inflammatory drugs and proton pump inhibitors are known to affect the diagnostics of gastrointestinal disorders. The aim of this study was to investigate to what extent omeprazole, diclofenac or co-administration of these affects faecal calprotectin levels and the normalisation interval after cessation.
Incidence and predisposing factors for de novo post-COVID-19 irritable bowel syndrome.
Postinfectious irritable bowel syndrome (IBS) is a known entity. We evaluated the incidence of post-COVID-19 IBS in patients discharged from the hospital and analyzed its correlation with the clinical and laboratory parameters, and treatment during the hospital stay.
DQA1*0102 DQB1*0602 haplotype distinguishes coeliac disease and its complications from gluten unrelated enteropathies.
De Silvestri, Annalisa a; Schiepatti, Annalisa b,c; Fowler, Bryce D b; Badulli, Carla d; Belvisi, Fabrizio d; Cacciatore, Rosalia e; Pasi, Annamaria e; Zingone, Fabiana f; Goodwin, John g; Key, Tim g; Rej, Anupam h; Sanders, David S h; Biagi, Federico b,c
doi : 10.1097/MEG.0000000000002480
Duodenal villous atrophy is due not only to coeliac disease and its complications but also to other rare enteropathies unrelated to gluten consumption, defined as noncoeliac enteropathies.
Role of endoscopic ultrasound in the evaluation of unexplained extrahepatic bile duct dilatation.
Chen, Long-Jiang a,*; Wang, Xiao-Yi b,*; Dai, Jian-Hua b,+; Tang, Zhi-Gang a,+
doi : 10.1097/MEG.0000000000002485
This study was performed to assess the diagnostic performance of endoscopic ultrasonography (EUS) in patients with extrahepatic bile duct (EBD) dilatation and develop a novel model incorporating EUS-based signature with clinical parameters for distinguishing the malignant dilation of EBD.
Can albumin reduce the mortality of patients with cirrhosis and ascites? A meta-analysis of randomized controlled trials.
Xu, Taichuan a; Liu, Wanjiang a; Huang, Ruizhen b
doi : 10.1097/MEG.0000000000002447
Albumin therapy in patients with decompensated liver cirrhosis has always been a controversial issue. This study aimed to investigate the efficacy and safety of albumin in reducing mortality and controlling complications in patients with liver cirrhosis and provide a reference for relevant decision-making.
Prognostic value and morphological findings of overexpression of glypican-3 in hepatocellular carcinoma.
Karaogullarindan, Umit; Gumurdulu, Yuksel; Uskudar, Oguz; Odabas, Emre; Guler, Hasan Selim; Tozluklu, Nur; Bagir, Emine; Kuran, Sedef
doi : 10.1097/MEG.0000000000002452
Hepatocellular carcinoma (HCC) is the seventh most common cancer all worldwide and is second in cancer-related deaths. In HCC, whose prognosis is still not good despite current treatments, there is a need for prognostic markers as well as early diagnosis.
Elevated serum levels of diamine oxidase, D-lactate and lipopolysaccharides are associated with metabolic-associated fatty liver disease.
Zhang, Ruike a,b,*; Chen, Ya-nan a,b,*; Zhang, Jixia a,b; Liu, Jing a,b
doi : 10.1097/MEG.0000000000002456
Studies have suggested an association between metabolic-associated fatty liver disease (MAFLD) and intestinal barrier function. The present study aims to investigate the association between MAFLD and intestinal barrier impairment in humans and identify potential risk factors for MAFLD.
Pharmacotherapeutic efficacy on noninvasive fibrosis progression in nonalcoholic fatty liver disease: a systematic review and network meta-analysis.
Kovalic, Alexander J. a; Gozar, Martin b; Da, Ben L. b; Bernstein, David b; Satapathy, Sanjaya K. b
doi : 10.1097/MEG.0000000000002463
Fibrosis impacts long-term outcomes among patients with nonalcoholic fatty liver disease (NAFLD). Due to well-documented flaws associated with liver biopsy, there has been a recent emphasis on prioritizing noninvasive testing over liver biopsy for the assessment of fibrosis.
Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe.
Murillo Perez, Carla F. a,b; Gerussi, Alessio c; Trivedi, Palak J. d; Corpechot, Christophe e; van der Meer, Adriaan J. b; Maria Battezzati, Pier f; Lindor, Keith D. g; Nevens, Frederik h; Kowdley, Kris V. i; Bruns, Tony j,k; Cazzagon, Nora l; Floreani, Annarosa l,m; Tanaka, Atsushi n; Ma, Xiong o; Mason, Andrew L. p; Gulamhusein, Aliya a; Ponsioen, Cyriel Y. q; Carbone, Marco c; Lleo, Ana r; Mayo, Marlyn J. s; Dalekos, George N. t; Gatselis, Nikolaos K. t; Thorburn, Douglas u; Verhelst, Xavier v; Pares, Albert w; Janssen, Harry L.A. a; Hirschfield, Gideon M. a; Hansen, Bettina E. a,x; Invernizzi, Pietro c; Lammers, Willem J. b; on behalf of the GLOBAL PBC Study Group
doi : 10.1097/MEG.0000000000002464
The are geographic variations in the incidence and prevalence of primary biliary cholangitis (PBC). The aim was to explore whether clinical outcomes of patients within Western Europe differ according to geographical region.
Efficacy evaluation and prognostic risk factors analysis of precise hepatectomy in the treatment of intermediate and advanced hepatocellular carcinoma.
Zhang, Junhong; Zeng, Qiang; Zhang, Pengfei; Chen, Yajie; Cao, Jinglin
doi : 10.1097/MEG.0000000000002460
To investigate the efficacy of precise hepatectomy in the treatment of patients with intermediate and advanced hepatocellular carcinoma and analyze the risk factors affecting prognosis.
Letter to the editor: response to 'Epidemiology and seasonal pattern in hospitalizations for microscopic colitis'.
Sohal, Aalam a; Chaudhry, Hunza b; Chintanaboina, Jayakrishna c
