Journal of Cosmetic Dermatology




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doi : 10.1111/jocd.15596

Volume 21, Issue 12

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JCD Editorial – December 2022

Michael H. Gold MD

doi : 10.1111/jocd.15549

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The significant value of sustainable cosmetics fragrance in the spotlight after COVID-19

Jinkyung Lee MS, Ki Han Kwon PhD

doi : 10.1111/jocd.15166

The coronavirus disease 2019 (COVID-19) pandemic has brought major changes to the world's population. This has led to increased wearing of masks to prevent infectious diseases, which can contribute to exacerbation of stress and the emergence of mental illness due to a physical health crisis.

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Nineteen months into the pandemic, what have we learned about COVID-19-related outcomes in patients with psoriasis?

Khalaf Kridin MD, PhD, Yochai Schonmann MD, MSc, Erez Onn MD, MHA, Dana Tzur Bitan PhD, Orly Weinstein MD, MPH, Eran Shavit MD, Arnon D. Cohen MD, MPH, PhD

doi : 10.1111/jocd.15351

The impact of psoriasis on the outcomes of Coronavirus disease 2019 (COVID-19) is yet to be precisely delineated.

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Lichen spinulosus following COVID-19 infection: Another possible cutaneous manifestation of COVID-19?

Aysel Cakir MD, Ecem Bostan MD, Ozay Gokoz MD

doi : 10.1111/jocd.15379

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The COVID-19 pandemic and its impact on esthetic dermatology

Zeinab Aryanian MD, Amirhooshang Ehsani MD, Zahra Razavi MD, Shahin Hamzelou MD, Zeinab Mohseni Afshar MD, Parvaneh Hatami MD

doi : 10.1111/jocd.15386

In general, the world population interest has increased for maintaining youthfulness and having better appearance since this leads to a better mental wellbeing and self-estimate.

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Effect of the COVID-19 vaccine on facial aesthetic injectables and suspension threads among patients treated by the Philippine Dermatological Society (PDS) dermatologists

Krisinda Clare C. Dim-Jamora MD, FPDS, Zharlah Gulmatico-Flores MD, FPDS, Ma. Cricelda Rescober-Valencia MD, FPDS, Stephen Lacson MD, FPDS, Michelle Ingente-Tablante MD, FPDS, Irene Gaile Robredo-Vitas MD, FPDS, Charlene Ang-Tiu MD, FPDS, Francesca Mari S. Sy-Alvarado MD, DPDS, Teresita S. Ferrariz MD, FPDS, Agnes Espinoza-Thaebtharm MD, FPDS

doi : 10.1111/jocd.15417

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COVID-19 vaccines and filler reactions: Should it be considered as a concern?

Zeinab Aryanian MD, Kamran Balighi MD, Seyed Naser Emadi MD, Zahra Razavi MD, Parvaneh Hatami MD, Zeinab Mohseni Afshar MD

doi : 10.1111/jocd.15428

Any implant or external material used in the body tissues can potentially be followed by autoimmune or inflammatory reactions. With the global vaccination program against COVID-19, the reports of tissue filler reactions would be increasingly demonstrated.

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COVID vaccine recommendations in dermatologic patients on immunosuppressive agents: Lessons learned from pandemic

Zeinab Aryanian MD, Kamran Balighi MD, Zeinab Mohseni Afshar MD, Mohammad Hossein Zamanian MD, Zahra Razavi MD, Parvaneh Hatami MD

doi : 10.1111/jocd.15448

Since SARS-CoV2 vaccines were approved without enough long-term monitoring due to emergent situations, some issues have been raised about timing and protocol of receiving them by patients treated by different immunosuppressive agents.

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Delayed nonlocal cutaneous reactions after inactive COVID-19 vaccinations

Öner Özdemir MD

doi : 10.1111/jocd.15455

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The significant transformation of life into health and beauty in metaverse era

Jinkyung Lee MS, Ki Han Kwon PhD

doi : 10.1111/jocd.15151

In 2019, coronavirus disease-19 (COVID-19) continues, and it is evolving and starting again. It is a situation to keep in mind that now is the era of With Corona (WC) and Long-COVID. “WC� will be a transformation of the quarantine system. The current situation is associated with health and beauty. Sustainability of healthy beauty is giving new meaning to well-being and well-dying.

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Novel pathway regarding good cosmetics brands by NFT in the metaverse world

Jinkyung Lee MS, Ki Han Kwon PhD

doi : 10.1111/jocd.15277

Globally, the coronavirus disease-19 (COVID-19) is an incomplete homework task. The society has transitioned into a non-face-to-face society due to COVID-19. Thus, research was conducted focusing on a new market in the cosmetic market using non-fungible token (NFT) in the metaverse era, a virtual world that is starting anew.

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A popularization of curation service for dermatological condition in Republic of Korea

Eunjeong Park BA, Ki Han Kwon PhD

doi : 10.1111/jocd.15340

Consumer and advanced consumption culture in modern society is an era that focuses on individual personality and value, and “my own customized products�, or customized marketing strategies, are actively being developed throughout the industry.

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Employing hyaluronic acid-based mesotherapy for facial rejuvenation

Behzad Iranmanesh MD, Maryam Khalili MD, Saman Mohammadi MD, Rezvan Amiri MD, Mahin Aflatoonian MD

doi : 10.1111/jocd.15341

Mesotherapy is a method of treatment in which biocompatible substances are injected in small aliquots into different levels of skin. This technique can be used for facial rejuvenation.

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Future perspective safe cosmetics: Focused on associated with ISO natural organic index

Jinkyung Lee MS, Ki Han Kwon PhD

doi : 10.1111/jocd.15398

As we enter the era of long COVID, recent studies on the relationship between coronavirus disease-19 (COVID-19) and skin are being conducted from various angles. Awareness of the safety of healthy skin is increasing.

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The applicability of scarcity, originality, and transaction tracking characteristics of the dermatological industry and non-fungible token

Hyejeong Koo MS, Ki Han Kwon PhD

doi : 10.1111/jocd.15406

The K-beauty industry has entered the global market and encompasses the global economy. In the future, it is necessary to recognize the need for rapid recognition and application of digital technologies such as non-fungible token (NFT) in a continuously changing and shared society.

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Applications of bakuchiol in dermatology: Systematic review of the literature

Carolina Puyana MD, MSPH, Neha Chandan MD, MPH, Maria Tsoukas MD, PhD

doi : 10.1111/jocd.15420

Bakuchiol (BAK), a meroterpene phenol abundant in the plant Psoralea corylifolia, is an emerging cosmeceutical agent with promising anti-aging, anti-inflammatory, and antibacterial properties.

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Efficacy and safety of tofacitinib for treatment of alopecia areata in children: A systematic review and meta-analysis

Elham Behrangi MD, Mahdieh Shokrollahi Barough PhD, Malihe Khoramdad MD, Pardis Hejazi MD, Masoud Pourghahramani Koltapeh MD, Azadeh Goodarzi MD

doi : 10.1111/jocd.15425

Tofacitinib, a potent JAK inhibitor, has gained increasing interest, in recent years, among dermatologists for the management of refractory alopecia areata.

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A cannabinoid Hairy-Tale: Hair loss or hair gain?

Aditya K. Gupta MD PhD, Mesbah Talukder PhD

doi : 10.1111/jocd.15427

Few studies have reported on the use of cannabinoid products to treat hair loss.

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The ubiquitin-proteasome system in melanin metabolism

Jingpei Shi MD, Yanfang Guo MD, Hanying Wang MD, Yun Xiao MD, Weimin Liu MD, Lechun Lyu MD

doi : 10.1111/jocd.15433

The ubiquitin-proteasome system (UPS) is a highly conserved way of regulating intracellular protein balance. UPS mediates proteolysis and disruption of variation or misfolding, while finely regulating proteins involved in differentiation and other biological processes.

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Potential application of natural bioactive compounds as skin-whitening agents: A review

Wei Zhao BE, Anquan Yang BE, Jing Wang MSc, Dan Huang BE, Yankang Deng BE, Xiaoli Zhang BE, Qingli Qu PhD, Wenjing Ma PhD, Ranhua Xiong PhD, Miaomiao Zhu PhD, Chaobo Huang PhD

doi : 10.1111/jocd.15437

Melanin is a skin pigment that gives color to the skin, hair, and eyes. The accumulation or over production of melanin can lead to aesthetic problems as well as serious diseases associated with hyperpigmentation.

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Irritant contact dermatitis caused by cosmetics containing excessive mercury

Sihao Sun MS, Jinxiu Chang MS, Xin Jiang MS, Hua Gu PhD

doi : 10.1111/jocd.15010

Irritant contact dermatitis (ICD) is a localized, nonimmune-induced inflammatory skin reaction, characterized by multiform skin lesions, including erythema, scaling, edema, blisters, and erosion. Mercury and its related compounds are highly allergic agents that can induce allergic contact dermatitis.

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Diversity trends in the leadership of the American Society for Laser Medicine And Surgery, 1996–2021

Jennifer C. Chen BA, Roy G. Geronemus MD, Hao Feng MD, MHS

doi : 10.1111/jocd.15361

To evaluate the temporal trends in diversity within the ASLMS board of directions from 1996 to 2021.

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Alopecia due to hair extensions successfully treated with hair transplantation

Esmeralda Lopez MD, Alexandre Catarino MD, Enrique Poblet MD, PhD, Francisco Jimenez MD

doi : 10.1111/jocd.15380

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Severe persistent urticaria following laser hair reduction

Noelle Dorgham MS III, Benjamin Witkoff DO, Eduardo Weiss MD, Brad Glick DO

doi : 10.1111/jocd.15390

Laser hair reduction is a common practice that utilized light-based therapy to prevent future hair growth. Complications following laser hair reduction treatment include thermal burns, which may lead to hyper- or hypopigmentation, hair stimulation, scar, or transient erythema of treated areas.

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Case report of possible iatrogenic Cushing's disease with low-dose prednisone to treat dermal filler hypersensitivity

Ricardo Grillo MSc

doi : 10.1111/jocd.15391

The aim of this article is to report a case of iatrogenic Cushing's disease associated with a delayed inflammatory response due to a facial dermal filler procedure.

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Social–economic impact of infection after cosmetic facial injection: A retrospective study

Shaoluan Zheng MD, Zihao Feng PhD, Chenxi Chen MSc, Anqi He MD, Jiaqi Liu PhD

doi : 10.1111/jocd.15012

The overwhelming interest in economically cost-effective treatments had led to an increase in the development of cosmetic facial injections. Concomitantly, complications have been also on the increasing trend. This article aimed to investigate the social–economic impact caused by infection after cosmetic facial injection.

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Lifting the midface using a hyaluronic acid filler with lidocaine: A randomized multi-center study in a Chinese population

Xiaojun Wang MD, Yan Wu MD, Bi Li MD, Xiongzheng Mu MD, Li Li MD

doi : 10.1111/jocd.15286

Soft-tissue augmentation of the midface is increasingly requested by patients, and hyaluronic acid (HA) fillers are frequently used in treatment.

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Evaluation of supratrochlear artery depth and course variations by Doppler ultrasonography along the glabellar frown lines for safer filler injections

Ulaş Güvenç MD, Barış Ten MD, Tamer İrfan Kaya MD, Hasan Hüsnü Yüksek MD, Ümit Türsen MD

doi : 10.1111/jocd.15338

Hyaluronic acid (HA) injection is a popular nonsurgical, rejuvenating procedure to treat glabellar frown lines, which has devastating complications such as blindness and skin necrosis due to the arterial occlusion of supratrochlear artery (STA).

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Clinical and histological comparative outcomes after injections of poly-L-lactic acid and calcium hydroxyapatite in arms: A split side study

Rosemarie Mazzuco MD, Cristiane Evangelista MD, Daniela Orso Gobbato MD, Luiz Mauricio de Almeida MD

doi : 10.1111/jocd.15356

Although much has been published on the use of poly-L-lactic acid (PLLA) and calcium hydroxyapatite (CaHA) for off-face indications, questions remain regarding their exact mechanisms of action in subcutaneous tissue and their comparative efficacy.

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Microbotox (Mesobotox) versus microneedling as a new therapeutic modality in the treatment of atrophic post-acne scars

Noha E. Mohamed MD, Samar N. Shabaan MD, Amel H. Raouf MSc

doi : 10.1111/jocd.15419

Given that most patients with moderate to severe acne develop post-acne scars, many treatment modalities can be used to ameliorate scaring; chemical peels, surgical excision, dermabrasion, fat transfer, autologous collagen, punch grafting, diverse filler injection, and lasers.

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Fractional microneedle radiofrequency treatment for enlarged facial pores: A real-world retrospective observational study on 75 patients

Kehui Ren BS, Houfang Liu BS, Bingyan Li BS, Bingrong Zhou MD, PhD

doi : 10.1111/jocd.15339

This study aimed to analyze the clinical results and influencing factors of the fractional microneedle radiofrequency (FMR) treatment for enlarged facial pores on different facial sites.

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Meta-analysis of fractional radiofrequency treatment for acne and/or acne scars

Jing Li MD, PhD, Fangfang Duan PhD, Jie Kuang MD

doi : 10.1111/jocd.15348

Fractional radiofrequency (FRF) is increasingly used for acne scars. The common coexistence of acne scars and active acne is a challenge in the timely management of acne scarring.

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Novel technique for rosacea treatment using optimal pulse technology: In vivo and clinical studies

Jiachen Yuan MD, iD, Yang Gao MD, Longquan Pi MD, PhD, Zhouna Li MD, PhD, Meilan Nan MD, PhD, Zhehu Jin MD, PhD, Chenglong Jin MD, PhD

doi : 10.1111/jocd.15384

Rosacea is a chronic inflammatory skin disease affecting the face, and the current treatment effect is not satisfactory.

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Q-switched frequency-doubled Nd:YAG (532 nm) laser versus trichloroacetic acid 35% peeling in the treatment of dorsal hand solar lentigo: An assessor-blind split-hand randomized controlled trial

Fariba Iraji MD, Azam Mousavi MD, Nazila Poostiyan MD, Mina Saber MD

doi : 10.1111/jocd.15385

Solar lentigo (SL) is a benign hyperpigmented spot occurring due to ultraviolet exposure, most commonly in the elderly. We aimed to compare the safety and efficacy of trichloroacetic acid (TCA) peeling with Q-switched laser in the treatment of SLs.

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Beneficial UVB phototherapy preceding a fractional CO2 laser-UVB protocol in refractory non-segmental vitiligo

Josiane Helou MD, Boutros Soutou MD, Ismael Maatouk MD, Reine Merhy MD, Joy Assaf MD, Anne-Sophie Sarkis MD, Rita Jabbour MD, Jérôme Kaikati MD, Roland Tomb MD, PhD

doi : 10.1111/jocd.15396

To explore the short- and long-term effects of UVB phototherapy preceding a fractional CO2 laser-UVB protocol in patients with resistant nonsegmental vitiligo.

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Efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of keloid: A randomized controlled trial

Atchima Suwanchinda MD, MSc, Thamthiwat Nararatwanchai MD, PhD

doi : 10.1111/jocd.15397

Keloid (KD) treatment is challenging for both physicians and patients. It can be functional debilitating and psychologically distressing. Available current therapeutics modalities give inconsistently effective results.

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Optimizing parameters of the Pulsed Dye Laser (PDL, 585-nm) for hemangioma treatment using diffuse reflectance spectroscopy

Ehsan Allahdadi MSc, Afshan Shirkavand PhD, Ezeddin Mohajerani PhD, Parvin Mansouri MD, Ali Almasi MSc, Somayeh Jahani Sherafat PhD

doi : 10.1111/jocd.15430

The lack of objectivity options for a specific individualized therapy might cause challenges in laser treatment. In other words, we need optimally determined laser parameters for less side effects.

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The efficacy and safety of the innovative cold atmospheric-pressure plasma technology in the treatment of striae distensae: A randomized controlled trial

Atchima Suwanchinda MD, MSc, Thamthiwat Nararatwanchai MD

doi : 10.1111/jocd.15458

Available current therapeutics modalities for striae distensae (SD) provide inconsistently effective outcomes. There is ongoing research on innovative treatment modalities to find better treatment solutions.

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Facial acne causes stigmatization among adolescents: A cross-sectional study

Marta Szepietowska, Alicja DÄ…browska, Bernadetta Nowak, Katarzyna Skinderowicz, Bartosz WilczyÅ„ski, Piotr K. Krajewski MD, Alina Jankowska-Konsur MD, PhD

doi : 10.1111/jocd.15268

Stigmatization is defined as a discrediting mark which sets the person from others and hindering interpersonal relationships. Literature data on stigma in acne subjects are scarce.

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Clinical evaluation of the brightening effect of chitosan-based cationic liposomes

Mi So Lee BA, Su Ji Kim MS, Jun Bae Lee PhD, Hyuk Sang Yoo PhD

doi : 10.1111/jocd.15350

Cationic liposomes can enhance the permeability of drugs in 3-D skin. Chitosan is considered a safe material for percutaneous delivery; thus, this study uses chitosan-incorporated cationic liposomes.

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Clinical evaluation of anti-aging effects of combined therapy�Azelaic acid, phytic acid, and vitamin C applied layer by layer in females with Fitzpatrick skin types II and III

Agata Markiewicz-Tomczyk MSc, Elżbieta Budzisz PhD, Anna Erkiert-Polguj MD, PhD

doi : 10.1111/jocd.15359

Vitamins C, E, and A and substances of plant origin, including azelaic acid and phytic acid are frequently used in cosmetic preparations to counteract oxidative stress and negative effects of free radicals.

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Safety and efficacy of a new hydrogel based on hyaluronic acid as cosmeceutical for xerosis

Nam Gyoung Ha MD, Seon Hwa Lee MD, Eun Hye Lee MD, Minyoul Chang PhD, Jeongsoo Yoo PhD, Weon Ju Lee MD, PhD

doi : 10.1111/jocd.15368

Hyaluronic acid (HA) is among the most effective and safe ingredients frequently used in cosmetics. However, a more economical and efficient formulation is still required.

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Whitening effect of kojic acid dipalmitate loaded nanosized ethosomal gel for the treatment of hyperpigmentation: In vitro and in vivo characterization

Nishma Tanveer PhD, Haji Muhammad Shoaib Khan PhD, Naveed Akhtar PhD

doi : 10.1111/jocd.15408

In recent years, the demands of depigmenting agents in cosmetics have been increased to treat skin conditions such as hyperpigmentation and melasma.

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Design and development of tranexamic acid loaded film-forming gel to alleviate melasma

Naga Thirumalesh Chevala M. Pharm, PhD, Jenica Alwin Dsouza B. Pharm, Hitesh Saini B. Pharm, Lalit Kumar M. Pharm, PhD

doi : 10.1111/jocd.15426

Melasma is a skin condition that causes increased epidermal pigmentation, enlarged melanocytes, increased melanosomes, solar elastosis, dermal blood vessels, and, occasionally, perivascular lymph histiocytic infiltrates.

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Status of cosmetic safety in Malaysia market: Mercury contamination in selected skin whitening products

Che Wan Jasimah Wan Mohamed Radzi PhD, Fatin Nur Majdina Nordin MPhil

doi : 10.1111/jocd.15429

Concern on cosmetic safety has been a subject of interest in recent years and is commonly associated with the exposure of the consumers to chemicals and impurities such as mercury contamination.

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Effects of perceived quality on consumer attitudes and satisfaction: Focus on lip products

Suyeun Lim MS, Ki Han Kwon PhD

doi : 10.1111/jocd.15457

Growth of national and economic development industrial and economic standards has raised women's social status, and the consumption value of aesthetic pursuit, which is the mainstream among women's diverse needs as consumers, has been increasing in quantities.

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A bibliometric and visualized research on global trends of abdominoplasty, 2011–2021

Tingting Xi MS, Rong Guo MD, Xuemei Wu MS, Hua Jiang MD, Jiachao Xiong MD

doi : 10.1111/jocd.15342

Patients with multiple pregnancies, multiple pregnancies, and a history of severe obesity, the abdominal wall muscles, and skin exhibit rectus abdominis separation and skin laxity due to prolonged overstretching, which causes damage to both the patient's appearance and health.

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Microliposuction and radiofrequency combined with the thread technique as a new method used in lower face lifting

Bo Yin MD, PhD, Xinyu Zhang MD, Facheng Li MD, PhD, Xuefeng Han MD, PhD

doi : 10.1111/jocd.15343

Minimally invasive facial rejuvenation is a popular and well-established treatment for patients seeking facial lifting.

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Alternative approach to treating dark circles: A case report

Ricardo Grillo MSc, Francisco Ubiratan Ferreira de Campos PhD, Tarley Eloi Pessoa de Barros PhD, Claudio Roberto Pacheco Jodas PhD

doi : 10.1111/jocd.15349

Dark circles under the eyes are a common condition worldwide with multiple treatment options. The aim of this paper is to report a case of dark circles treated with ozone therapy, which showed a very reasonable clinical improvement.

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Acne and its post-inflammatory hyperpigmentation treatment by applying anti-acne dissolving microneedle patches

Meiling Tai MS, Chenggong Zhang ME, Yonghao Ma PhD, Jian Yang MM, Zhuoxian Mai MChem, Chengguo Li PhD, Gang Leng PhD

doi : 10.1111/jocd.15352

Acne is a significant problem in young people. At present, most acne treatment products are topically applied cosmetics, whose efficacy is limited by the stratum corneum.

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Frequency of skin cancer and evaluation of risk factors: A hospital-based study from Turkey

Arzu FerhatosmanoÄŸlu MD, Leyla Baykal Selcuk MD, Deniz Aksu Arıca MD, Åžafak Ersöz MD, SavaÅŸ Yaylı MD

doi : 10.1111/jocd.15355

Skin cancers are the most common type of cancer with a significantly increasing incidence.

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Evaluating the effectiveness of stromal-vascular fraction (SVF) cells along with subcision method in the treatment of acne scars: A double-blind randomized controlled clinical trial study

Masoumeh Roohaninasab MD, Azadeh Seifadini MD, Najmolsadat Atefi MD, Afsaneh Sadeghzadeh-Bazargan MD, Azadeh Goodarzi MD, Amir Reza Hanifnia MD, Maryam Nouri MD, Sona Zare PhD, Sepideh Moradi MD, Abbas Dehghani MD, Mohammad Ali Nilforoushzadeh MD, Elham Behrangi MD

doi : 10.1111/jocd.15375

Subcision method is one of the main techniques for treatment of acne scars or stromal-vascular fraction (SVF) and combined therapy can improve treatment strategy.

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Decellularized human amniotic membrane engraftment in combination with adipose-derived stem cells transplantation, synergistically improved diabetic wound healing

Sima Davoodi, Roohollah Ebrahimpour-Malekshah, Ã–mer Ayna, Mitra Akbari, Amir Raoofi, Hossein Mokhtari, Mostafa Izanlu, Faezeh Modanloo, Davood Nasiry

doi : 10.1111/jocd.15394

One of the most important and common complications of diabetes is a disorder and defect in diabetic wound healing.

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The influence of wearing a mask on the projected first impressions and attractiveness levels of smiling individuals

Steven Dayan MD, Sabrina Fabi MD, Nimit Gandhi MD, Isabel Scharf BS, Alexea Resner BA, Lien Lian, Eljona Kola MS, Zainab Jabri

doi : 10.1111/jocd.15395

To evaluate the effect of mask wearing on facial attractiveness and projected first impressions during the COVID-19 pandemic.

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Evaluation of clinical efficacy and laboratory indicators of non-cultured epidermal cell suspension and hair follicle cell suspension in surgical management of stable vitiligo: A randomized comparative trial

Apoorva Challa MSc, Suman Chauhan MSc, Rashi Pangti MD, Sudheer Kumar Arava MD, Sapna Prajapati PhD, Anjali Pandey PhD, Somesh Gupta MD

doi : 10.1111/jocd.15407

Non-cultured epidermal cell suspension (ECS) and hair follicle cell suspension (HFCS) are well-established methods of surgical treatment of stable vitiligo.

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Picture-based acne lesion counts: A validation study to assess accuracy and reliability of acne lesion counts via photography

Michael H. Gold MD, Ashish Bhatia MD, Arshdeep Kaur MS, Margot Doucette BS, Amogh Kothare MS

doi : 10.1111/jocd.15413

Acne lesion counting (ALC) is widely used to evaluate efficacy of new acne treatments. Although such evaluations are precise and highly discriminative, if assessed live, it can be a time-consuming and intrusive measurement.

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Aesthetic considerations for treating the North American multi-ethnic patient: Thriving in diversity international roundtable series

Sabrina Guillen Fabi MD, FAAD, FAACS, Valerie D. Callender MD, Wendy W. Lee MD, Steven Dayan MD

doi : 10.1111/jocd.15422

The United States is becoming increasingly diverse, and between 2016 and 2019, an increase of 945 832 aesthetic procedures was recorded for Hispanic, African American, and Asian American patients combined.

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Randomized trial of microneedling combined with 2% minoxidil topical solution for the treatment of female pattern hair loss in a Chinese population

Yao Zhang MD, Youyu Sheng MD, Yibin Zeng MD, Ruiming Hu MD, Jun Zhao MD, Wuqing Wang MD, Qinping Yang MD

doi : 10.1111/jocd.15424

To evaluate the efficacy and safety of 2% minoxidil combined with microneedling in the treatment of female pattern hair loss.

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The modified inframammary fold suture method and its clinical significance in primary augmentation mammoplasty

Feng Qin MD, Ang Zeng MD, Nanze Yu MD, Ruijia Dong MD, Fei Long MD, Zenan Xia MD, Wenchao Zhang MD, Xiao Long MD, Xiaojun Wang MD

doi : 10.1111/jocd.15432

The inframammary approach is one of the most commonly used incisions in breast augmentation.

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Comparison of two devices for facial skin analysis

Madison K. Cook BS, Margaret A. Kaszycki BS, Irma Richardson MHA, Sarah L. Taylor MD, MPH, Steven R. Feldman MD, PhD

doi : 10.1111/jocd.15434

The use of quantitative measures to assess patients' skin has turned the subjective nature of dermatology into an objective one.

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Basal cell skin cancers: Retrospective analysis of 67 cases

Rafet Ozbey MD

doi : 10.1111/jocd.15441

Basal cell carcinoma (BCC) is the most common skin cancer and originates from the basal layer of the epidermis. It is most common in the head and neck region. It usually grows slowly and rarely metastasizes. The gold standard treatment is surgical excision.

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An assessment for measuring loneliness, anxiety, and depression in male patients with androgenetic alopecia undergoing hair transplantation surgery: A before-after study

Mohammad Ali Nilforoushzadeh MD, Maryam Golparvaran PhD

doi : 10.1111/jocd.15452

Androgenetic alopecia has a significant influence on the patients' loneliness, anxiety, and depression, although there are numerous strategies to improve the patients' loneliness, anxiety, and depression.

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Metabolic syndrome and dyslipidemia in xanthelasma palpebrarum and associated risk–2 factors–A case-control study

Komal Agarwal MD, Padmaja Saikia MD, Indrashis Podder MD, DNB

doi : 10.1111/jocd.15353

Xanthelasma palpebrarum (XP) primarily causes cosmetic disfigurement. However, systemic associations like metabolic syndrome (MetS) and dyslipidemia need consideration.

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Protective role of Caesalpinia sappan extract and its main component brazilin against blue light–induced damage in human fibroblasts

Jong Il Park PhD, Sung Jae Kim MD, Yong Jae Kim MD, Seung Ji Lee PhD

doi : 10.1111/jocd.15354

Ultraviolet (UV) radiation is a well-known factor that causes skin aging. Recently, with the development of technology, the skin has been exposed to not only the UV radiation but also the blue light from electronic devices.

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Interleukin-18 serum level before and after intralesional immunotherapy with tuberculin purified protein derivative in patients with cutaneous and genital warts

Hadeer Hazem Abo Korsa MSc, Hebat-Allah Hassan Nashaat MD, Halim Maher Halim MD, Mona A. Atwa MD, Radwa El-Sayed Mahmoud Marie MD

doi : 10.1111/jocd.15358

Several studies demonstrated the efficacy of intralesional purified protein derivative (PPD) immunotherapy in warts eradication.

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Study on the correlation of high expression level of HuD with seborrheic keratosis and skin aging

Juping Chen MD, Jun Liu BM, Zheng Wang MD, Jiandan Xu MM, Jia Tao MM, Hualing Li MD

doi : 10.1111/jocd.15360

Currently, most studies of ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-like protein 4 (Hu antigen D, HuD) focus on nervous system-related diseases; the role of HuD in the occurrence of skin aging and seborrheic keratosis (SK) has not been reported.

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Evaluation of serum TWEAK, TRAIL, and oxidative stress markers in rosacea patients

Imge Durmaz MD, Dursun Turkmen MD, Nihal Altunisik MD, Nuray Uremis PhD, Muhammed Mehdi Uremis PhD, Serpil Sener MD, Yusuf Turkoz MD

doi : 10.1111/jocd.15365

Rosacea is a chronic inflammatory skin disease of unknown pathogenesis. TWEAK and TRAIL are two cytokines thought to have a role in the pathogenesis of some inflammatory and autoimmune diseases.

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Analysis of risk factors for quality management to blepharoplasty based on DEMATEL-ISM

Jianfei Zhang MD, Pengpeng Han MCH, Hui Yuan MCH, Yujun Tang MD, Feng Yang MCH

doi : 10.1111/jocd.15366

Blepharoplasty is a typical complex structural system, which involves many factors and the interaction among them.

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Correlation of skin cancer and actinic keratosis-related knowledge and sun protection behaviors and sunscreen use among a sample of Jordanian population

Mais M. Saleh PhD, Oriana Awwad PhD, Mariam Hantash Abdel Jalil PhD, Walid Al-Qerem PhD, Maen Saleh MD, Yazan Al Thaher PhD, Sharif Abdelghany PhD

doi : 10.1111/jocd.15377

The incidence of skin cancer and actinic keratosis has increased worldwide. Measuring the public awareness, attitude, and knowledge about these diseases and the skin protection behaviors are highly important to undertake preventive measures.

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Nitric oxide synthase activity: A novel potential biomarker for predicting Alopecia areata

Seyhan Taskin PhD, Hakim Celik PhD, Gokhan Cakirca MD, Vildan Manav MD, Abdullah Taskin PhD

doi : 10.1111/jocd.15378

Alopecia areata is a dermatological disease characterized by nonscarring type hair loss. The cause of Alopecia areata not known exactly but studies support that it has an autoimmune etiology in which oxidative stress play an important role.

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Influence of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid on facial skin lipidome among seborrhea participants

Chanidapa Wongtada MD, Putthamas Pewlong BSc, Pravit Asawanonda MD, DSc, Nopadon Noppakun MD, Pornkanok Pongpamorn PhD, Atchara Paemanee PhD, Supaart Sirikantaramas PhD, Chanat Kumtornrut MD, MSc

doi : 10.1111/jocd.15381

A better understanding of skin lipidomics and its alteration under treatment administration might offer therapeutic solutions for seborrhea.

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Glycyrrhizic acid suppresses atopic dermatitis-like symptoms by regulating the immune balance

Dian-Dong Hou PhD, Xin-Xin Wang PhD, Si-Jia Li PhD, De-Cheng Wang MD, Yuan Niu BS, Zi-Ran Xu BS, Zhuo-Qun Jin BS

doi : 10.1111/jocd.15383

Glycyrrhiza is one of the most widely used traditional Chinese medicines in China. Its main bioactive ingredient glycyrrhizic acid (GA) has the potential to be used as a treatment for atopic dermatitis (AD) because it has similar actions to steroids, but with relatively few side effects.

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Evaluation of serum levels of interleukins 1-beta, 10 and 12 in patients with acne vulgaris

Marwa Mohamed MD, Hanan Abdel Aaty Shehata MBBCH, Nahed Fathallah Fahmy MD, Ramadan Saleh MD

doi : 10.1111/jocd.15399

One of the most prevalent skin disorders is acne vulgaris. It is a distressing problem among young adults and adolescents. The pathophysiology of AV is significantly influenced by certain immune response cells.

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The effect of patient characteristics on illness perception and sun protection behaviors in melasma

Ecem Cantürk Nazli MD, Ceylan Avcı MD, Sevgi Akarsu MD

doi : 10.1111/jocd.15401

Melasma, a significant cosmetic problem, has been accepted by some authors as a photoaging illness in recent times. There is no published study evaluating the effects of the clinical and sociodemographic findings on illness perception and sun protection behaviors (SPBs) in patients with melasma.

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Formulation and characterization of Anacyclus Pyrethrum Emulgels and its in vitro and in vivo evaluation as cosmeceutical product

Muhammad Saleem Qureshi PhD, Qazi Adnan Jamil PhD, Naveed Akhtar PhD, Naheed Akhtar PhD

doi : 10.1111/jocd.15404

Plants containing high phenolic and flavonoids contents used widely as antioxidant agent by reducing skin photo damaging effects and play important role in skin rejuvenating.

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An improved explants culture method: Sustainable isolation of keloid fibroblasts with primary characteristics

Yan He MD, Shengpeng Zhang MD, Wu Bao MD, Yi Xue MD, Bin Yin MD, Xialin Cheng MD, Zexin Zhang MD, Chiyu Jia MD, PhD

doi : 10.1111/jocd.15416

Keloid (KD) is a complex fibroproliferative disease, but the exact mechanisms underlying keloid pathogenesis remain to be elucidated. The primary keloid fibroblasts (KFs) culture in vitro has always been a fundamental measure to study the pathogenesis of keloid. However, the traditional primary culture methods have some limitations, such as a long culture cycle, low specimen utilization rate and so on.

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Observation of the clinical efficacy of isotope phosphorus-32 dressing combined with diprospan and mucopolysaccharide polysulphate cream in the treatment of keloids

Bin-yu Zhuang MD, Fang-chi Hu MM, Yan You MD, Liang Zhang MM

doi : 10.1111/jocd.15418

The present study aims to investigate the effectiveness, recurrence, and adverse reaction rates of isotope phosphorus-32 dressings combined with diprospan and mucopolysaccharide polysulphate cream in the treatment of keloids.

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Transplantation of autologous epidermal melanocyte–keratinocyte cells suspension for cell therapy of vitiligo: A clinical evaluation and biometric assessment

Mohammad Ali Nilforoushzadeh MD, Susan Farshi MD, MPH, Maryam Nouri MD, Shiva Alavi MD, Batool Bayat Tork MSC, Fariba Jaffary MD, Sona Zare PHD

doi : 10.1111/jocd.15423

Among several surgical treatments, the use of transplantation of epidermal cultured melanocytes or melanocytes–keratinocytes cell suspension has gained many researchers and dermatologists' attention as a new technique for the treatment of vitiligo.

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Assessment of Brassica oleraceae L. (Brassicaceae) extract loaded ethosomal gel as a versatile vesicular carrier system for dermocosmetic application: A noninvasive split-faced study

Palwasha Khan PharmD, MPhil, Naveed Akhtar PhD, Haji Muhammad Shoaib Khan PhD, Rabia Tasneem PharmD, MPhil, Hafiz Saqib Zaka PharmD, MPhil, Naheed Akhtar PhD, Arfa Sharif PhD

doi : 10.1111/jocd.15436

Plant extracts with rich ascorbic acid contents have greater antioxidant capability; extensively employed in skin beautifying products and protect skin from detrimental photodamaging environmental effects.

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Clinical outcomes of hereditary angioedema on multiparous women

Esra Karabiber MD, Reşat Kendirlinan MD, Pamir Çerçi MD

doi : 10.1111/jocd.15438

Significant concerns for patients with hereditary angioedema (HAE) include hormonal fluctuations and drug safety during pregnancy. The impact of the disease on childbearing in multiparous women remains to be elucidated. We aimed to investigate the clinical course and impacts of multiparity on HAE patients.

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Different vitiligo characteristics as predictors of increased risk of metabolic syndrome and insulin resistance: A case–control study

Sarah Ibrahim MD, Samar El-Tahlawi MD, Rania M. Mogawer MD, Mervat El Ansary MD, Samia Esmat MD, Marwa El-Hawary MD

doi : 10.1111/jocd.15446

Autoimmune and metabolic disturbances have been reported in association with vitiligo, highlighting possible systemic associations that should be considered.

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Does trigonelline help skin tone? Molecular docking studies of trigonelline on the human tyrosinase, formulation, optimization, and characterization of an emulgel-containing Trigonella foenum-graecum L. fenugreek standardized hydroalcoholic extract

Moein Masjedi PhD, Aida Solhjoo PhD

doi : 10.1111/jocd.15453

This study aimed to perform molecular docking studies to identify possibilities of the inhibitory potential of the trigonelline present in fenugreek seeds on the human tyrosinase, standardize fenugreek extract, formulate, and characterize an emulgel-containing fenugreek extract-entrapped niosomal vesicles.

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Evaluation of the serum C-reactive protein–albumin ratio and its relationship with disease severity IN alopecia areata: A prospective case–control study

Bülent Nuri Kalaycı MD, Ä°lknur Balta MD

doi : 10.1111/jocd.15460

Alopecia areata (AA) is an autoimmune and inflammatory disease characterized by localized or diffuse non-scarring hair loss. The serum C-reactive protein (CRP)/albumin ratio (CAR) is a novel inflammatory marker and a significant prognostic indicator in several diseases.

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Comment on: Bicalutamide and the new perspectives for female pattern hair loss treatment: What dermatologists should know

Ralph M. Trüeb MD, Ngoc-Nhi C. Luu MD, Natalia Caballero Uribe MD, Antonia Régnier MD

doi : 10.1111/jocd.14936

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Proton pump inhibitors-related subacute cutaneous lupus erythematosus: Clinical characteristics, management, and outcome

Zhenzhen Deng MD, Aiyuan Guo PhD, Cuifang Wu MD, Chunjiang Wang PhD

doi : 10.1111/jocd.15450

Previous knowledge about the association between proton pump inhibitors (PPIs) exposure and subacute cutaneous lupus erythematosus (SCLE) was mainly based on limited case reports or few review studies. We aim to evaluate the clinical characteristics, management, and outcome in patients with PPIs-induced SCLE.

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Mean platelet volume may not be a marker of inflammation in patients with seborrheic dermatitis

Cengiz Beyan MD, Esin Beyan MD

doi : 10.1111/jocd.15045

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Comment on “intralesional injection of MMR, BCG, and candida albicans antigen in treatment of multiple recalcitrant warts�

Rujittika Mungmunpuntipantip PhD, Viroj Wiwanitkit MD

doi : 10.1111/jocd.15119

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Erythema papulatum centrifugum: A probably underdiagnosed cause of annular erythema

Muazzez Cigdem Oba MD, Tugba Akin MD, Filiz Yilmaz MD

doi : 10.1111/jocd.15132

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Complete blood cell count parameters and seborrheic dermatitis: Preanalytical and analytical considerations

John L. Frater MD, Maria Yadira Hurley MD

doi : 10.1111/jocd.15289

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Concerning the characterization of metabolic syndrome in epidemiologic studies. Comments on “metabolic syndrome in melasma: A case–control study�

Maria Paula Barbieri D'Elia MD, Daniel Cassiano MD, Ana Cláudia Cavalcante Esposito MD, MSc, Hélio Amante Miot MD, PhD

doi : 10.1111/jocd.15347

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Can hair cast be a helpful dermoscopic diagnostic clue in telogen effluvium?

Robabeh Abedini MD, Mohammad Jafferany MD, Azadeh Goodarzi MD, Mahshid Sadat Ansari MD, Mahsa Ansari MD, Sepehr Khosravi MD, Samaneh Mozafarpoor MD

doi : 10.1111/jocd.15362

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Reply to Correspondence

Havva Hilal Ayvaz, Mehmet Emre Sivrice, Emrah Atay

doi : 10.1111/jocd.15364

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New diagnostic approach in seborrheic keratosis: Cryosign

Aslan Yürekli MD, Bengü Nisa Akay MD

doi : 10.1111/jocd.15367

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Use of the rapid scoop biopsy forceps to perform biopsies in difficult-to-reach areas

Elie Saliba MD, Abrar A. Qureshi MD, MPH

doi : 10.1111/jocd.15371

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Permanent leukotrichia after picosecond laser treatment for tattoo removal

Yujin Han MD, Suyeun Kim MD, Yu Ri Woo MD, PhD, Sang Hyun Cho MD, PhD, Jeong Deuk Lee MD, PhD, Hei Sung Kim MD, PhD

doi : 10.1111/jocd.15372

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Reply to the letter “cutaneous adverse events following the inactivated and mRNA COVID-19 vaccines: Correspondence�

Ecem Bostan MD, Beril Yel MD, Aysen Karaduman MD

doi : 10.1111/jocd.15376

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A case of multiple pyogenic granulomas of the trunk successfully treated with topical β-blockers

Anissa Zaouak MD, Refka Frioui MD, Amal Chamli MD, Imen Helal MD, Ehsen Ben Brahim MD, Samy Fenniche MD, Houda Hammami MD

doi : 10.1111/jocd.15382

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Granulomatous deposition after calcium hydroxylapatite filler injection

Kyohei Itamura MD, Adrian E. House MD, Henry Pokress, Babak Larian MD, Babak Azizzadeh MD

doi : 10.1111/jocd.15387

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Iatrogenic arsenicosis in a young female causing cosmetic distress

Tanvi Dev MD, Nikhil Mehta MD, Mohamad Goldust MD, Ejaz Khan MBBS, Somesh Gupta MD

doi : 10.1111/jocd.15388

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Inflammatory reaction to recently applied red tattoo ink after COVID-19

Uwe Wollina MD

doi : 10.1111/jocd.15389

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Generalized pruritic skin erythema with scales on an old man

Kun-E. Lu MD, Wei Li MD, PhD, Sui-Qing Cai MD, PhD

doi : 10.1111/jocd.15392

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Quantitative skin pigmentation analysis among North Indians

Prashita Dabas MSc, Himanshu Khajuria PhD, Sonal Jain PhD, Sarjana Dutt PhD, Kallur Nava Saraswathy PhD, Biswa Prakash Nayak PhD

doi : 10.1111/jocd.15403

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Fractional Erbium: Yag laser versus combination of fractional Erbium: Yag laser with topical platelet-rich plasma for facial rejuvenation

Sahar Dadkhahfar MD, Arash Rahbar MD, Zohreh Tehranchinia MD, Hamideh Moravvej MD

doi : 10.1111/jocd.15410

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Multilevel suture treatment can be used for regression or disappearance of the double-eyelid folds

Shuai Jin MM, Xiaowei Jing MB, Zhongmin Jin MB

doi : 10.1111/jocd.15412

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Facial Bier spots: What to consider in this atypical localization?

Muazzez Cigdem Oba MD, Defne Özkoca MD, Deniz Mutlu MD, Burhan Engin MD

doi : 10.1111/jocd.15440

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Dystrophic xanthomization secondary to lichen planus pigmentosus associated with frontal fibrosing alopecia

Alejandro Lobato-Berezo MD, Mónica Gonzalez-Farré MD, Orianna Marcantonio MD, Ramon M. Pujol MD, PhD

doi : 10.1111/jocd.15444

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Retracted: Metabolic Syndrome in Melasma: A case-control study

doi : 10.1111/jocd.15076

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