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Message From the Editors to Our Reviewers
José G. Merino, Olga Ciccarelli, Bradford B. Worrall, Anthony A. Amato, Rebecca Burch, Jonathan Graff-Radford, Jennifer Graves, Peter Hedera, Linda A. Hershey, Barbara C. Jobst, Renée A. Shellhaas
doi : 10.1212/WNL.0000000000012241
vol. 97 no. 1 3-11
Intrathecal Production of MOG-IgG
Yael Hacohen, View ORCID ProfileWesley Kerr, View ORCID ProfilePatrick Waters
doi : 10.1212/WNL.0000000000012215
vol. 97 no. 1 12-13
National Estimates of Subarachnoid Hemorrhage Burden Need to Account for Within-Country Variations
Valery L. Feigin
doi : 10.1212/WNL.0000000000012241
vol. 97 no. 1 14-15
Autoimmune Encephalitis in First Episode Psychoses
Maarten J. Titulaer, View ORCID ProfileGregory S. Day
doi : 10.1212/WNL.0000000000012177
vol. 97 no. 1 16-17
Difference in the Source of Anti-AQP4-IgG and Anti-MOG-IgG Antibodies in CSF in Patients With Neuromyelitis Optica Spectrum Disorder
Tetsuya Akaishi, Toshiyuki Takahashi, Tatsuro Misu, Kimihiko Kaneko, Yoshiki Takai, Shuhei Nishiyama, Ryo Ogawa, Juichi Fujimori, Tadashi Ishii, Masashi Aoki, Kazuo Fujihara, Ichiro Nakashima
doi : 10.1212/WNL.0000000000012131
vol. 97 no. 1 e1-e12
To elucidate the differences in the source and in the level of intrathecal synthesis between anti–aquaporin-4 antibodies (AQP4-IgG) and anti-myelin oligodendrocyte glycoprotein antibodies (MOG-IgG).
Breast Cancer Survival in Multiple Sclerosis
Ruth Ann Marrie, Colleen Maxwell, Alyson Mahar, Okechukwu Ekuma, Chad McClintock, Dallas Seitz, Patti Groome
doi : 10.1212/WNL.0000000000012195
vol. 97 no. 1 e13-e22
To test the hypotheses that overall survival and cancer-specific survival after breast cancer diagnosis would be lower in persons with multiple sclerosis (MS) as compared to persons without MS using a retrospective matched cohort design.
Association of Central Hypersomnia and Fatigue in Patients With Multiple Sclerosis
Anne-Laure Dubessy, Sophie Tezenas du Montcel, Frederique Viala, Rana Assouad, Michel Tiberge, Caroline Papeix, Catherine Lubetzki, Michel Clanet, Isabelle Arnulf, Bruno Stankoff
doi : 10.1212/WNL.0000000000012175
vol. 97 no. 1 e23-e33
To evaluate sleepiness and central hypersomnia in multiple sclerosis (MS)–associated fatigue, we performed long-term polysomnography in patients with MS and healthy controls.
Association of Migraine With Incident Hypertension After Menopause
Conor James MacDonald, Douae El Fatouhi, Anne-Laure Madika, Guy Fagherazzi, Tobias Kurth, Gianluca Severi, Marie-Christine Boutron-Ruault
doi : 10.1212/WNL.0000000000012127
vol. 97 no. 1 e34-e41
Migraine has been identified as a potential risk factor for hypertension in prospective studies. In women, migraine prevalence decreases after menopause, but no studies have determined whether migraine is associated with hypertension after menopause. This study sought to determine whether history of migraine was associated with an increased risk of hypertension among menopausal women.
Stroke Prediction Based on the Spontaneous Nystagmus Suppression Test in Dizzy Patients
Georgios Mantokoudis, Thomas Wyss, Ewa Zamaro, Athanasia Korda, Franca Wagner, Thomas C. Sauter, Hassen Kerkeni, Roger Kalla, Miranda Morrison, Marco Domenico Caversaccio
doi : 10.1212/WNL.0000000000012120
vol. 97 no. 1 e42-e51
Failure of fixation suppression of spontaneous nystagmus is sometimes seen in patients with vestibular strokes involving the cerebellum or brainstem; however, the accuracy of this test for the discrimination between peripheral and central causes in patients with an acute vestibular syndrome (AVS) is unknown.
Substantial Within-Country Variation in the Incidence of Subarachnoid Hemorrhage
Ilari Rautalin, Joni Valdemar Lindbohm, Jaakko Kaprio, Miikka Korja
doi : 10.1212/WNL.0000000000011986
vol. 97 no. 1 e52-e60
To study whether the incidence of subarachnoid hemorrhage (SAH) varies between geographic regions of Finland.
Clinical, Neuroimmunologic, and CSF Investigations in First Episode Psychosis
Mar Guasp, Eloi Giné-Servén, Estibaliz Maudes, Mireia Rosa-Justicia, Eugenia Mart?nez-Hern?ndez, Ester Boix-Quintana, Miquel Bioque, Virginia Casado, Yasmina M?dena-Ouarzi, Nicolau Guanyabens, Desiree Muriana, Gisela Sugranyes, Isabella Pacchiarotti, Eva Davi-Loscos, Cristina Torres-Rivas, José R?os, Lidia Sabater, Albert Saiz, Francesc Graus, Josefina Castro-Fornieles, Eduard Parellada, Josep Dalmau
doi : 10.1212/WNL.0000000000012176
vol. 97 no. 1 e61-e75
To report the neuropsychiatric features and frequency of NMDA receptor (NMDAR) and other neuronal immunoglobulin G antibodies in patients with first episode psychosis (FEP) and to assess the performance of reported warning signs and criteria for autoimmune psychosis (AP).
Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease
Anna H. Boerwinkle, Julie K. Wisch, Charles D. Chen, Brian A. Gordon, Omar H. Butt, Suzanne E. Schindler, Courtney Sutphen, Shaney Flores, Aylin Dincer, Tammie L.S. Benzinger, Anne M. Fagan, John C. Morris, Beau M. Ances
doi : 10.1212/WNL.0000000000012129
vol. 97 no. 1 e76-e87
To evaluate temporal correlations between CSF and neuroimaging (PET and MRI) measures of amyloid, tau, and neurodegeneration in relation to Alzheimer disease (AD) progression.
Primary Progressive Aphasia Associated With GRN Mutations
Dario Saracino, Sophie Ferrieux, Marie Noguès-Lassiaille, Marion Houot, Aurélie Funkiewiez, Leila Sellami, Vincent Deramecourt, Florence Pasquier, Philippe Couratier, Jérémie Pariente, Amandine Géraudie, Stéphane Epelbaum, David Wallon, Didier Hannequin, Olivier Martinaud, Fabienne Clot, Agnès Camuzat, Simona Bottani, Daisy Rinaldi, Sophie Auriacombe, Marie Sarazin, Mira Didic, Claire Boutoleau-Bretonnière, Christel Thauvin-Robinet, Julien Lagarde, Carole Roué-Jagot, François Sellal, Audrey Gabelle, Frédérique Etcharry-Bouyx, Alexandre Morin, Cinzia Coppola, Richard Levy, Bruno Dubois, Alexis Brice, Olivier Colliot, Maria Luisa Gorno-Tempini, Marc Teichmann, Raffaella Migliaccio, Isabelle Le Ber, on behalf of the French Research Network on FTD/FTD-ALS
doi : 10.1212/WNL.0000000000012191
vol. 97 no. 1 e88-e102
To determine relative frequencies and linguistic profiles of primary progressive aphasia (PPA) variants associated with GRN (progranulin) mutations and to study their neuroanatomic correlates.
SARS-CoV-2 Encephalitis Presenting as a Clinical Cerebellar Syndrome
Katryn Oosthuizen, Elizabeth Christina Steyn, Lawrence Tucker, Innocent Vusumusi Ncube, Diana Hardie, Suzaan Marais
doi : 10.1212/WNL.0000000000012123
vol. 97 no. 1 27-29
Current Status and Future Strategies for Mentoring Women in Neurology
Amtul S. Farheen, Ilena C. George, Divya Singhal, Regina M. Troxell, Jyoti Pillai, Logan Schneider, Catherine Lomen-Hoerth, Jennifer S. Graves, Stefano Sandrone, Christa O'Hana S. Nobleza
doi : 10.1212/WNL.0000000000012174
vol. 97 no. 1 30-37
The American Academy of Neurology's (AAN) 2017 Gender Disparity Report identified improving mentorship as a key intervention to fill the leadership and pay gaps for women in neurology. Here we summarize the literature on mentoring women, provide an outline of ideal components of programs geared toward closing gender gaps, and present a mentoring program for AAN members. The strategies discussed share similarities with those for closing gaps related to race, ethnicity, and religion. Developing effective mentorship and sponsorship programs is essential to ensure a sufficiently diverse pool of academic faculty and private practitioners and to establish equal representation in leadership roles in this field.
Cerebellar Syringocephaly Following Surgery for Chiari Malformation
Ismaël Mahazou, Mohamed Choukri, Fabrice Parker, Steven Knafo
doi : 10.1212/WNL.0000000000012051
vol. 97 no. 1 38-39
Child Neurology: Hereditary Folate Malabsorption
Akshata Huddar, Shwetha Chiplunkar, Madhu Nagappa, Periyasamy Govindaraj, Sanjib Sinha, Arun B. Taly, Bindu Parayil Sankaran
doi : 10.1212/WNL.0000000000012242
vol. 97 no. 1 40-43
Educational Research: Why Medical Students Choose Neurology
Sarah Grzebinski, Helen Cheung, Charles Sanky, Jessica Ouyang, Stephen Krieger
doi : 10.1212/WNL.0000000000012128
vol. 97 no. 1 e103-e108
To understand medical students' motivations for choosing neurology and how applicants conceptualize the field, as this information can be used to enhance interest in neurology and develop educational programs to help identify, support, and recruit future neurologists.
Teaching NeuroImages: Neuroimaging Findings in Inosine Triphosphate Pyrophosphohydrolase Deficiency
Karthik Muthusamy, Suzanne Boyer, Marc Patterson, Jorgen Bierau, Saskia Wortmann, Eva Morava
doi : 10.1212/WNL.0000000000012083
vol. 97 no. 1 e109-e110
Teaching Video NeuroImages: Infratentorial Multiple Sclerosis Relapse Presenting as Continuous Hemifacial Myokymia
Manuel Salavisa, Filipa Serrazina, Pedro Pires, Ana Sofia Correia
doi : 10.1212/WNL.0000000000011753
vol. 97 no. 1 e111-e112
Editors' Note: White Matter Hyperintensities Mediate the Association of Nocturnal Blood Pressure With Cognition
Ariane Lewis, Steven Galetta
doi : 10.1212/WNL.0000000000011719
vol. 97 no. 1 44
Reader Response: White Matter Hyperintensities Mediate the Association of Nocturnal Blood Pressure With Cognition
Mark J. Fisher, Annlia Paganini-Hill, Claudia H. Kawas, Maria M. Corrada, Evan Fletcher
doi : 10.1212/WNL.0000000000012052
vol. 97 no. 1 44-45
Reader Response: White Matter Hyperintensities Mediate the Association of Nocturnal Blood Pressure With Cognition
Nevio Cimolai
doi : 10.1212/WNL.0000000000012213
vol. 97 no. 1 45
Author Response: White Matter Hyperintensities Mediate the Association of Nocturnal Blood Pressure With Cognition
Anthony G. Chesebro, Jesus D. Melgarejo, Reinier Leendertz, Kay C. Igwe, Patrick J. Lao, Krystal K. Laing, Batool Rizvi, Mariana Budge, Irene B. Meier, Gustavo Calmon, Joseph H. Lee, Gladys Maestre, Adam M. Brickman
doi : 10.1212/WNL.0000000000012214
vol. 97 no. 1 46
Editors' Note: Teaching NeuroImages: Pseudopathologic Brain Parenchymal Enhancement due to Vascular Compression in Parotid Tumor
Ariane Lewis, Steven Galetta
doi : 10.1212/WNL.0000000000012216
vol. 97 no. 1 46-47
Reader Response: Teaching NeuroImages: Pseudopathologic Brain Parenchymal Enhancement due to Vascular Compression in Parotid Tumor
Lizhang Chen, Hongbo Zheng
doi : 10.1212/WNL.0000000000012217
vol. 97 no. 1 47-48
Author Response: Teaching NeuroImages: Pseudopathologic Brain Parenchymal Enhancement due to Vascular Compression in Parotid Tumor
Bernardo C.A. Teixeira, Zeferino Demartini, Debora B. Bertholdo, Luiz O.M. Coelho, Dante L. Escuissato
doi : 10.1212/WNL.0000000000012218
vol. 97 no. 1 48-49
