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Beneficial effects of whole-body vibration exercise for brain disorders in experimental studies with animal models: a systematic review
A.L.B.D. Cardoso a,b,*, Danúbia C. S �a-Caputo b, Nasser R. Asad b, Marieke JG van Heuvelen d, Eddy A. van der Zee e, Anderson Ribeiro-Carvalho c, Mario Bernardo-Filho
doi : 10.1016/j.bbr.2022.113933
Volume 431, 5 August 2022, 113933
Brain disorders have been a health challenge and is increasing over the years. Early diagnosis and interventions are considered essential strategies to treat patients at risk of brain disease.
Blockade of the mineralocorticoid receptors in the medial prefrontal cortex prevents the acquisition of one-trial tolerance in mice
Kairo Alan Albernaz-Mariano a,b, Rimenez Rodrigues Souza c,d, Azair Canto-de-Souza a,b,e,f,*,1
doi : 10.1016/j.bbr.2022.113938
Volume 431, 5 August 2022, 113938
One-trial tolerance (OTT) is characterized by the lack of anxiolytic-like effects of benzodiazepines in animals submitted to a trial 2 in the elevated plus-maze (EPM) and is described to be influenced by learning mechanisms.
Sevoflurane inhibits histone acetylation and contributes to cognitive dysfunction by enhancing the expression of ANP32A in aging mice
Gaoshang Chai a, Jiajun Wu a, Rongfei Fang a, Yanlin Liu a, Xuechun Wang a, Xi Wang a, Jinming Zhang a, Jiali Zhou a, Zhiqian Jiang a, Haiyan Yi a, Yunjuan Nie a, Peng Zhao a, Dengxin Zhang
doi : 10.1016/j.bbr.2022.113949
Volume 431, 5 August 2022, 113949
Postoperative cognitive dysfunction (POCD) is a major clinical complication after surgery under general anesthesia, particularly in elderly patients, but the mechanisms remain unclear.
LncRNA DLX6-AS1 promotes microglial inflammatory response in Parkinson's disease by regulating the miR-223–3p/NRP1 axis
Lin Liu a, Tingting Zhou a, Tao Li a, Zhanhua Liang a,*, Xiaoguang Luo
doi : 10.1016/j.bbr.2022.113923
Volume 431, 5 August 2022, 113923
Parkinson's disease (PD) is a prevailing neurodegenerative disorder. This study discussed the mechanism of lncRNA distal-less homeobox 6 antisense 1 (DLX6-AS1) on inflammatory responses in PD.
Sequential delay and probability discounting tasks in mice reveal anchoring effects partially attributable to decision noise
Gerardo R. Rojas, Lisa S. Curry-Pochy, Cathy S. Chen, Abigail T. Heller, Nicola M. Grissom
doi : 10.1016/j.bbr.2022.113951
Volume 431, 5 August 2022, 113951
Delay discounting and probability discounting decision making tasks in rodent models have high translational potential. However, it is unclear whether the discounted value of the large reward option is the main contributor to variability in animals’ choices in either task, which may limit translation to humans.
Activation and blockade of 5-HT4 receptors in the dorsal hippocampus enhance working and hippocampus-dependent memories in the unilateral 6-hydroxydopamine lesioned rats
Jia-Wei Wang a, Jian Liu a, Zhao-Long Wang a, Feng Gao a, Jie Yang a, Xiao-Chen Wang a, Yuan Guo a, Yong Wang a, Bo-Rui Ma a, Hui-Sheng Wang a, Yi-Wei Hu a, Yu-Ming Zhang b, Yan-Ping Hui c, Li Zhang
doi : 10.1016/j.bbr.2022.113952
Volume 431, 5 August 2022, 113952
Cognitive dysfunction is a common symptom in Parkinson’s disease (PD). Serotonin4 (5-HT4) receptors are richly expressed in the dorsal hippocampus (dHIPP) and play an important role in cognitive activities. However, the mechanism underlying the role of dHIPP 5-HT4 receptors in PD-related cognitive dysfunction remains unclear.
Spatial selectivity of the visual duration aftereffect in the sub-second range: An event-related potentials study
Bingxin Lin a,b,c,d, Youguo Chen a,b,c,d, Baolin Li e, Andrew Avitt f, Yunfei Guo a,b,c,d, Li Pan a,b,c,d, Xiting Huang
doi : 10.1016/j.bbr.2022.113950
Volume 431, 5 August 2022, 113950
Prolonged adaptation to one duration biases the perception of subsequent durations in a phenomenon known as duration adaptation.
D-cycloserine rescues scopolamine-induced deficits in cognitive flexibility in rats measured by the attentional set-shifting task
Md. Abu Bokor Siddik a,b, Markus Fendt
doi : 10.1016/j.bbr.2022.113961
Volume 431, 5 August 2022, 113961
Cognitive flexibility facilitates adaptions to a changing environment in humans and animals and can be assessed with the attentional set shifting task (ASST). In various learning paradigms for laboratory rodents, the partial NMDA receptor agonist D-cycloserine has been found to have pro-cognitive effects.
Rapid decay of spatial memory acquired in rats with ventral hippocampus lesions
Juan M.J. Ramos
doi : 10.1016/j.bbr.2022.113962
Volume 431, 5 August 2022, 113962
Several memory consolidation theories have proposed that following a learning situation the hippocampus gradually stabilizes labile recent memories into long-lasting remote memories.
Testing a cascade model linking prenatal inflammation to child executive function
Marie Camerota a,1, Amanda C. Wylie a,b, Jessica Goldblum a,b, Laurie Wideman c, Carol L. Cheatham b,d, Cathi B. Propper
doi : 10.1016/j.bbr.2022.113959
Volume 431, 5 August 2022, 113959
Inflammation during pregnancy is beginning to be understood as a risk factor predicting poor infant health and neurodevelopmental outcomes. The long-term sequelae associated with exposure to prenatal inflammation are less well established.
Effects of thymoquinone on scopolamine-induced spatial and echoic memory changes through regulation of lipid peroxidation and cholinergic impairment
Deniz Kantar a,*, Alev Duygu Acun a, Betül Danıs ̧man
doi : 10.1016/j.bbr.2022.113972
Volume 431, 5 August 2022, 113972
Thymoquinone (TMQ), one of the main components active of Nigella sativa, shows very useful biomedical properties. Evidence suggests that cholinergic dysfunction and oxidative stress play role in the pathogenesis of neurodegenerative disorders such as Alzheimer’s disease (AD).
