Bipolar Disorders




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Issue Information

doi : 10.1111/bdi.13219

Volume 24, Issue 7

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Linking scientific research to the bipolar consumer patient

Katrin I. Kutlucinar, Kathryn Burrows

doi : 10.1111/bdi.13265

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Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative

Katherine E. Burdick, Caitlin E. Millett, Anastasia K. Yocum, Cara M. Altimus, Ole A. Andreassen, Valerie Aubin, Raoul Belzeaux, Michael Berk, Joanna M. Biernacka, Hilary P. Blumberg, Anthony J. Cleare, Claudia Diaz-Byrd, Caroline Dubertret, Bruno Etain, Lisa T. Eyler, Brent P. Forester, Janice M. Fullerton, Mark A. Frye, Sébastien Gard, Ophelia Godin, Emmanuel Haffen, Federica Klaus, Trine Vik Lagerberg, Marion Leboyer, Anabel Martinez-Aran, Susan McElroy, Philip B. Mitchell, Emilie Olie, Phebe Olorunfemi, Christine Passerieux, Amy T. Peters, Daniel L. Pham, Mircea Polosan, Julia R. Potter, Martha Sajatovic, Ludovic Samalin, Raymund Schwan, Megan Shanahan, Brisa Solé, Rebecca Strawbridge, Amanda L. Stuart, Ivan Torres, Torrill Ueland, Eduard Vieta, Lana J. Williams, Anna L. Wrobel, Lakshmi N. Yatham, Allan H. Young, Andrew A. Nierenberg, Melvin G. McInnis

doi : 10.1111/bdi.13208

Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate and compare the influence of key factors on community function in multiple cohorts of well-characterized samples of individuals with BD.

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Risk factors for early recurrence after discontinuing lithium in bipolar disorder

Ross J. Baldessarini, Marco Pinna, Martina Contu, Gustavo H. Vázquez, Leonardo Tondo

doi : 10.1111/bdi.13206

Time to a new episode of bipolar disorder (BD) is shorter after discontinuing lithium rapidly. We now address this and other factors associated with the risk of early illness after discontinuing lithium.

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The nosological status of unipolar mania and hypomania within UK Biobank according to objective and subjective measures of diurnal rest and activity

Natasha Sangha, Laura Lyall, Cathy Wyse, Breda Cullen, Heather C. Whalley, Daniel J. Smith

doi : 10.1111/bdi.13237

There is uncertainty whether unipolar mania is a discrete sub-type of bipolar disorder. Disrupted rest/activity rhythms are a key feature of bipolar disorder (BD) but have not been well characterised in unipolar mania/hypomania (UM). We compared subjective and objective rest/activity patterns, demographic and mental health outcomes across BD, UM and control groups.

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Lithium replacement dose recommendations using Monte Carlo simulations

Janthima Methaneethorn, Zola Mannie, Erica Bell, Gin S. Malhi

doi : 10.1111/bdi.13241

Missed medication doses are a common clinical problem, and cause consternation when prescribing lithium because its plasma levels must be kept within a narrow therapeutic window. Therefore, this study set out to determine the potential impact of missed lithium doses on its pharmacokinetics, and to explore the optimal compensatory dosing scheme. This is difficult to determine clinically and in research because of ethical constraints and therefore we modelled the effects using simulations.

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A risk calculator to predict suicide attempts among individuals with early-onset bipolar disorder

Tina R. Goldstein, John Merranko, Danella Hafeman, Mary Kay Gill, Fangzi Liao, Craig Sewall, Heather Hower, Lauren Weinstock, Shirley Yen, Benjamin Goldstein, Martin Keller, Michael Strober, Neal Ryan, Boris Birmaher

doi : 10.1111/bdi.13250

To build a one-year risk calculator (RC) to predict individualized risk for suicide attempt in early-onset bipolar disorder.

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Case reports are valuable for psychiatry

Kuan Tsee Chee, Qin Xiang Ng

doi : 10.1111/bdi.13252

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Future directions: A comment on the recommendations for the management of patients with mixed presentations

Jared K. O'Garro-Moore, Jessica L. Hamilton

doi : 10.1111/bdi.13260

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Acute onset psychosis�the diagnosis lies in your ‘hands’

Urmi Khanna, Kavish Singh

doi : 10.1111/bdi.13253

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Bipolar maelstrom: Diagnostic uncertainties and treatment challenges

Verinder Sharma, Shannon Brauen

doi : 10.1111/bdi.13238

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Possible association of 5-HT4 receptor agonist prucalopride in a 52-year-old man with an index manic episode

Evguenia Makovkina, Benjamin D. Brody, Charles Shaffer

doi : 10.1111/bdi.13245

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Medical comorbidities leading to hypernatremia during COVID-19 pandemic in patients with mood disorders on long-term lithium therapy

Kyohei Otani, Kaori Mogi, Atsumi Miura, Hiroyuki Miyai, Haruko Fukushima, Kunitaka Matsuishi

doi : 10.1111/bdi.13195

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